IMP: Integrative Multi-species Prediction

Danio rerio

56 genes annotated in zebrafish

Multi-species View

positive regulation of signaling

GO:0023056

Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.

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Known genes in the process in zebrafishInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of signaling"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of signaling" (in gray)

Name	Description	Probability	Func Analog Organism
bmp2b	bone morphogenetic protein 2b	0.952	Human Mouse
dharma	dharma	0.864
bmp2a	bone morphogenetic protein 2a	0.858	Human Mouse
plcg1	phospholipase C, gamma 1	0.805
dkk1b	dickkopf 1b	0.777	Mouse
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.711	Zebrafish
ndr2	nodal-related 2	0.677	Zebrafish
evx1	even-skipped homeobox 1	0.640
fgf3	fibroblast growth factor 3	0.609
chd	chordin	0.600
fn1	fibronectin 1	0.562
shha	sonic hedgehog a	0.546	Mouse Fly
klf4	Kruppel-like factor 4	0.532
sulf1	sulfatase 1	0.493	Human Fly
tbx16	T-box gene 16	0.492
gli1	GLI-Kruppel family member 1	0.455
tbx1	T-box 1	0.447	Mouse
fgf8a	fibroblast growth factor 8 a	0.429
efnb2a	ephrin B2a	0.425
acvr1b	activin A receptor, type IB	0.417	Human Rat Fly
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.411	Mouse
sox9a	SRY-box containing gene 9a	0.408	Mouse
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.406
ntla	no tail a	0.394
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.389
tnfrsfa	tumor necrosis factor receptor superfamily, member a	0.386	Human
sox32	SRY-box containing gene 32	0.384
ptch1	patched 1	0.367
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.336
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.335
neurog1	neurogenin 1	0.324
rag1	recombination activating gene 1	0.309
sparc	secreted acidic cysteine rich glycoprotein	0.306
cdx4	caudal type homeo box transcription factor 4	0.296
nrg1	neuregulin 1	0.281	Mouse
pkd2	polycystic kidney disease 2	0.279	Human
cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.272
nadl1.2	neural adhesion molecule L1.2	0.267	Mouse
foxa2	forkhead box A2	0.266	Mouse
gli2a	GLI-Kruppel family member GLI2a	0.265	Zebrafish
ywhaba	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a	0.261	Fly
eve1	even-skipped-like1	0.258
bmp7a	bone morphogenetic protein 7a	0.256	Human Zebrafish
bbc3	BCL2 binding component 3	0.251	Human
fzd7a	frizzled homolog 7a	0.251
tbx6	T-box gene 6	0.247
wnt4a	wingless-type MMTV integration site family, member 4a	0.246	Zebrafish
eya1	eyes absent homolog 1	0.237	Mouse
wnt10a	wingless-type MMTV integration site family, member 10a	0.234	Zebrafish
appb	amyloid beta (A4) precursor protein b	0.231
cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.227	Mouse Fly
acvr2a	activin receptor IIa	0.213	Human Rat
disp1	dispatched homolog 1 (Drosophila)	0.212
ywhae1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1	0.212	Fly
klf4a	Kruppel-like transcription factor 4a	0.211
rarab	retinoic acid receptor, alpha b	0.209
trim3a	tripartite motif-containing 3a	0.199
cd63	Cd63 antigen	0.197
zbtb4	zinc finger and BTB domain containing 4	0.196
dync1h1	dynein, cytoplasmic 1, heavy chain 1	0.193
lft1	lefty1	0.192
robo3	roundabout homolog 3	0.188	Zebrafish
brd4	bromodomain containing 4	0.188
yap1	Yes-associated protein 1	0.178	Mouse
ahr2	aryl hydrocarbon receptor 2	0.176
mespb	mesoderm posterior b	0.175	Mouse
cdh2	cadherin 2, neuronal	0.175	Mouse
ryk	receptor-like tyrosine kinase	0.175	Human
igf1	insulin-like growth factor 1	0.174
dusp6	dual specificity phosphatase 6	0.172
angptl2	angiopoietin-like 2	0.172
ihha	Indian hedgehog homolog a	0.169	Mouse Fly
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.168
ywhai	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide	0.166	Fly
spry4	sprouty (Drosophila) homolog 4	0.163
fgfr1b	fibroblast growth factor receptor 1b	0.162	Human Mouse Fly
jag1b	jagged 1b	0.162	Mouse
boc	brother of CDO	0.161
map3k4	mitogen activated protein kinase kinase kinase 4	0.161	Human Mouse Fly
mga	MAX gene associated	0.160
frem3	Fras1 related extracellular matrix 3	0.156
spry2	sprouty homolog 2	0.155
robo2	roundabout homolog 2	0.155	Zebrafish
dlx5a	distal-less homeobox gene 5a	0.153	Mouse
psen1	presenilin 1	0.152	Mouse Worm
fgfr1a	fibroblast growth factor receptor 1a	0.152	Human Mouse Fly
ldb1a	LIM-domain binding factor 1a	0.151
hmx1	H6 homeo box 1	0.151
flt4	fms-related tyrosine kinase 4	0.150	Human Fly
fezf2	FEZ family zinc finger 2	0.148
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.147
itgb1a	integrin, beta 1a	0.145
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.145
fzd7b	frizzled homolog 7b	0.145
col1a1a	collagen, type I, alpha 1a	0.143	Human
nog1	noggin 1	0.142
ext2	exostoses (multiple) 2	0.142
vent	ventral expressed homeobox	0.139
egr2b	early growth response 2b	0.139
runx2b	runt-related transcription factor 2b	0.139
dcn	decorin	0.138
nrg2a	neuregulin 2a	0.137
furina	furin (paired basic amino acid cleaving enzyme) a	0.137
mbtps1	membrane-bound transcription factor protease, site 1	0.136
bdnf	brain-derived neurotrophic factor	0.135
socs3a	suppressor of cytokine signaling 3a	0.132
flh	floating head	0.132
wnt3a	wingless-type MMTV integration site family, member 3A	0.129	Human Zebrafish Mouse
alas2	aminolevulinate, delta-, synthetase 2	0.128
mc4r	melanocortin 4 receptor	0.127
ywhabl	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like	0.126	Fly
si:ch211-212m21.5	si:ch211-212m21.5	0.125
csnk1da	casein kinase 1, delta a	0.124	Human
nf1a	neurofibromin 1a	0.123	Mouse
cltca	clathrin, heavy polypeptide a (Hc)	0.122	Fly
ins	preproinsulin	0.121	Mouse
oxtl	oxytocin-like	0.121
extl3	exostoses (multiple)-like 3	0.120
six4.3	sine oculis homeobox homolog 4.3	0.120
cpsf6	cleavage and polyadenylation specific factor 6	0.119
twist3	twist3	0.118
cdh23	cadherin-like 23	0.117
rhoaa	ras homolog gene family, member Aa	0.117	Yeast Worm
th	tyrosine hydroxylase	0.117
fgf13b	fibroblast growth factor 13b	0.117	Zebrafish
ptpra	protein tyrosine phosphatase, receptor type, A	0.116
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.116
sfrp1b	secreted frizzled-related protein 1b	0.111	Human Mouse
ift88	intraflagellar transport 88 homolog	0.110
dag1	dystroglycan 1	0.109
wnt5b	wingless-type MMTV integration site family, member 5b	0.108	Human Zebrafish Mouse
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.108	Mouse
atp1a3a	ATPase, Na+/K+ transporting, alpha 3a polypeptide	0.108
dld	deltaD	0.108	Mouse
sfrp5	secreted frizzled-related protein 5	0.108
admp	anti-dorsalizing morphogenic protein	0.108	Zebrafish
vsx1	visual system homeobox 1 homolog, chx10-like	0.108
tp53bp2	tumor protein p53 binding protein, 2	0.106
pcdh8	protocadherin 8	0.105
brd2a	bromodomain-containing 2a	0.105
otpa	orthopedia homolog a	0.104
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.103	Rat
irx4a	iroquois homeobox protein 4a	0.103
tnfsf10l2	tumor necrosis factor (ligand) superfamily, member 10 like 2	0.103	Human Zebrafish
fos	v-fos FBJ murine osteosarcoma viral oncogene homolog	0.102
fzd3a	frizzled homolog 3a	0.101
dlc	deltaC	0.101
foxo3b	forkhead box O3b	0.100	Fly
mxtx2	mix-type homeobox gene 2	0.100
hes6	hairy and enhancer of split 6 (Drosophila)	0.100
ywhabb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b	0.099
phox2a	paired-like homeobox 2a	0.099
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.099
ptk2.1	protein tyrosine kinase 2a	0.098	Human Rat
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.098
pou5f1	POU domain, class 5, transcription factor 1	0.098
nog2	noggin 2	0.097
fgf17	fibroblast growth factor 17	0.097	Zebrafish
lhx2b	LIM homeobox 2b	0.096
hsd3b1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	0.096
stau2	staufen, RNA binding protein, homolog 2 (Drosophila)	0.094
cyp19a1a	cytochrome P450, family 19, subfamily A, polypeptide 1a	0.094
maff	v-maf musculoaponeurotic fibrosarcoma oncogene homolog f (avian)	0.094
lama5	laminin, alpha 5	0.094
wnt3	wingless-type MMTV integration site family, member 3	0.094	Zebrafish
prnprs3	prion protein, related sequence 3	0.093
tgfbi	transforming growth factor, beta-induced	0.092
sf3b1	splicing factor 3b, subunit 1	0.092
tll1	tolloid-like 1	0.091
snai1b	snail homolog 1b (Drosophila)	0.090
tgfb3	transforming growth factor, beta 3	0.088	Mouse Rat
gro2	groucho 2	0.087
hoxb5b	homeo box B5b	0.087
ihhb	Indian hedgehog homolog b	0.086	Mouse Fly
pob	partial optokinetic response b	0.086
rargb	retinoic acid receptor, gamma b	0.086
sfrp1a	secreted frizzled-related protein 1a	0.086	Human Mouse
dip2c	DIP2 disco-interacting protein 2 homolog C (Drosophila)	0.085
flr	fleer	0.084
lepr	leptin receptor	0.084
chia.2	chitinase, acidic.2	0.084
ybx1	Y box binding protein 1	0.084
baxa	bcl2-associated X protein, a	0.084	Human Mouse
dvl2	dishevelled, dsh homolog 2 (Drosophila)	0.084	Human Mouse
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.084	Human
wnt8b	wingless-type MMTV integration site family, member 8b	0.083	Zebrafish
adra2a	adrenergic, alpha-2A-, receptor	0.083	Human
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.082
mapk12	mitogen-activated protein kinase 12	0.082
rhoub	ras homolog gene family, member Ub	0.081
dnmt4	DNA (cytosine-5-)-methyltransferase 4	0.081
nlgn2b	neuroligin 2b	0.081
nkx3.2	NK3 homeobox 2	0.081
podxl	podocalyxin-like	0.081
celf1	cugbp, Elav-like family member 1	0.081
lef1	lymphocyte enhancer binding factor 1	0.080
arhgef7b	Rho guanine nucleotide exchange factor (GEF) 7b	0.080
ass1	argininosuccinate synthetase 1	0.080
esr2a	estrogen receptor 2a	0.079	Rat
brpf1	bromodomain and PHD finger containing, 1	0.079
ip6k2	inositol hexaphosphate kinase 2	0.079
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.078
mapk1	mitogen-activated protein kinase 1	0.078	Fly
ywhaqb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b	0.078	Fly
igfbp1b	insulin-like growth factor binding protein 1b	0.077
nadl1.1	neural adhesion molecule L1.1	0.076	Mouse
gdf9	growth differentiation factor 9	0.076
hoxd4a	homeo box D4a	0.076
emx3	empty spiracles homeobox 3	0.076
acvr1l	activin A receptor, type I like	0.076
etv5a	ets variant 5a	0.076
elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.075
gata3	GATA-binding protein 3	0.075	Human
fzd10	frizzled homolog 10	0.075	Human
cacna1ab	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b	0.074
oep	one-eyed pinhead	0.074
ca2	carbonic anhydrase II	0.073	Mouse
enpp1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.073
ctgf	connective tissue growth factor	0.073	Human
nrp2b	neuropilin 2b	0.073
wu:fb58e05	wu:fb58e05	0.072
mst1	macrophage stimulating 1 (hepatocyte growth factor-like)	0.072
cpne1	copine I	0.071
ikzf5	IKAROS family zinc finger 5	0.071
spsb4a	splA/ryanodine receptor domain and SOCS box containing 4a	0.070
ptpn11a	protein tyrosine phosphatase, non-receptor type 11, a	0.070	Human Mouse
hoxa2b	homeo box A2b	0.068
gfra1b	gdnf family receptor alpha 1b	0.068
cyp24a1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.068
si:dkeyp-7c9.1	si:dkeyp-7c9.1	0.068
col8a1a	collagen, type VIII, alpha 1a	0.068
vcanb	versican b	0.067
inhbaa	inhibin, beta Aa	0.067	Human
gpia	glucose phosphate isomerase a	0.067
bmper	BMP binding endothelial regulator	0.067
runx3	runt-related transcription factor 3	0.066	Mouse
drd2l	dopamine receptor D2 like	0.066
ift57	intraflagellar transport protein 57	0.066
atp6v0ca	ATPase, H+ transporting, lysosomal, V0 subunit c, a	0.065	Human
eif1b	eukaryotic translation initiation factor 1B	0.065
lgals9l1	lectin, galactoside-binding, soluble, 9 (galectin 9)-like 1	0.064	Human
cfl2l	cofilin 2, like	0.063
ntn2	netrin 2	0.063
cxcr4b	chemokine (C-X-C motif), receptor 4b	0.063
litaf	lipopolysaccharide-induced TNF factor	0.062	Human
ptena	phosphatase and tensin homolog A	0.062	Mouse
npy8br	neuropeptide Y receptor Y8b	0.062
gata4	GATA-binding protein 4	0.062
prkci	protein kinase C, iota	0.062
irx4b	iroquois homeobox protein 4b	0.062
nkx2.2a	NK2 transcription factor related 2a	0.061
epas1b	endothelial PAS domain protein 1b	0.061
aox3	aldehyde oxidase 3	0.061
cdh4	cadherin 4, retinal	0.061
gpib	glucose phosphate isomerase b	0.061
runx2a	runt-related transcription factor 2a	0.061
hif1al	hypoxia-inducible factor 1, alpha subunit, like	0.060
bida	BH3 interacting domain death agonist	0.060
aplnrb	apelin receptor b	0.060
myoz1b	myozenin 1b	0.060
dmrta2	doublesex and mab-3 related transcription factor like family A2	0.060
sept7b	septin 7b	0.060
fn1b	fibronectin 1b	0.060
irf9	interferon regulatory factor 9	0.060
pou4f1	POU domain, class 4, transcription factor 1	0.060
zeb1	zinc finger E-box binding homeobox 1	0.060
ctsl1b	cathepsin L, 1 b	0.059
her7	hairy and enhancer of split related-7	0.059
sox10	SRY-box containing gene 10	0.058
wnt10b	wingless-type MMTV integration site family, member 10b	0.058	Zebrafish Mouse
leo1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.058
igf1rb	insulin-like growth factor 1b receptor	0.058	Human Mouse
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.058
otpb	orthopedia homolog b	0.057
m17	IL-6 subfamily cytokine M17	0.057
LOC566020	Gig2-like protein DreO	0.057
ephb3a	eph receptor B3a	0.057
tlr18	toll-like receptor 18	0.057
tal1	T-cell acute lymphocytic leukemia 1	0.057
wnt2	wingless-type MMTV integration site family member 2	0.057	Zebrafish
sdcbp	syndecan binding protein (syntenin)	0.057
lman2	lectin, mannose-binding 2	0.057
crb2a	crumbs homolog 2a	0.056
tuba1l	tubulin, alpha 1, like	0.056
adipor1b	adiponectin receptor 1b	0.056
gata2a	GATA-binding protein 2a	0.056
mc1r	melanocortin 1 receptor	0.056	Mouse
robo1	roundabout homolog 1	0.056	Zebrafish
golga1	golgin A1	0.056
ret1	receptor tyrosine kinase	0.056	Human
cdh5	cadherin 5	0.056
try	trypsin	0.055
nr2f2	nuclear receptor subfamily 2, group F, member 2	0.055
wu:fb63c04	wu:fb63c04	0.055
odc1	ornithine decarboxylase 1	0.055
arf2	ADP-ribosylation factor 2	0.055
msnb	moesin b	0.055
epha4b	eph receptor A4b	0.055
mib	mind bomb	0.055
mapk3	mitogen-activated protein kinase 3	0.055	Human Fly
gpr98	G protein-coupled receptor 98	0.055
hnf4a	hepatocyte nuclear factor 4, alpha	0.054	Rat
insra	insulin receptor a	0.054	Human
ube2v2	ubiquitin-conjugating enzyme E2 variant 2	0.054
foxh1	forkhead box H1	0.054
alcama	activated leukocyte cell adhesion molecule a	0.054
fbxl14b	F-box and leucine-rich repeat protein 14b	0.054
gsc	goosecoid	0.054	Zebrafish
ptprf	protein tyrosine phosphatase, receptor type, F	0.053
zgc:65827	zgc:65827	0.053
eif3hb	eukaryotic translation initiation factor 3, subunit H, b	0.052
mobkl3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.052
cyt1	type I cytokeratin, enveloping layer	0.052
wnt8a	wingless-type MMTV integration site family, member 8a	0.052
wif1	wnt inhibitory factor 1	0.052	Fly
angpt2	angiopoietin 2	0.052
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.052
aclya	ATP citrate lyase a	0.052
sox9b	SRY-box containing gene 9b	0.052
prkcz	protein kinase C, zeta	0.051	Human Rat
sema3ab	semaphorin 3ab	0.051
kif17	kinesin family member 17	0.051
hgd	homogentisate 1,2-dioxygenase	0.051
pafah1b1b	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b	0.051	Mouse
epb4.1l4	erythrocyte protein band 4.1-like 4	0.051	Zebrafish
ralgapa1	Ral GTPase activating protein, alpha subunit 1 (catalytic)	0.051
zgc:64040	zgc:64040	0.051
dusp2	dual specificity phosphatase 2	0.050
sumo3a	SMT3 suppressor of mif two 3 homolog 3a	0.050	Fly
chmp5	chromatin modifying protein 5	0.050
csad	cysteine sulfinic acid decarboxylase	0.050
mapk4	mitogen-activated protein kinase 4	0.050
her1	hairy-related 1	0.050
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.050
mecp2	methyl CpG binding protein 2	0.050	Mouse
gas8	growth arrest-specific 8	0.049
zgc:92851	zgc:92851	0.049
bmpr2a	bone morphogenetic protein receptor, type II a (serine/threonine kinase)	0.049
eomesa	eomesodermin homolog a	0.049
cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	0.048
hif1ab	hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b	0.048	Mouse
mao	monoamine oxidase	0.048
scd	stearoyl-CoA desaturase (delta-9-desaturase)	0.048
atf3	activating transcription factor 3	0.048
tfpi2	tissue factor pathway inhibitor 2	0.048
sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.047
zgc:63721	zgc:63721	0.047
cotl1	coactosin-like 1 (Dictyostelium)	0.047
rbp1a	retinol binding protein 1a, cellular	0.047
heyl	hairy/enhancer-of-split related with YRPW motif-like	0.047
col27a1a	collagen, type XXVII, alpha 1a	0.047
alk	anaplastic lymphoma kinase (Ki-1)	0.047
bmp4	bone morphogenetic protein 4	0.047	Human Mouse
lasp1	LIM and SH3 protein 1	0.047
sulf2	sulfatase 2	0.047	Human Fly
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.047	Human Zebrafish
cldnc	claudin c	0.046
lpp	LIM domain containing preferred translocation partner in lipoma	0.046
ahi1	Abelson helper integration site 1	0.046
rarga	retinoic acid receptor gamma a	0.046
epas1a	endothelial PAS domain protein 1a	0.046
slc4a2a	solute carrier family 4, anion exchanger, member 2a	0.046
erbb3a	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a	0.046
hk1	hexokinase 1	0.046
fgfr2	fibroblast growth factor receptor 2	0.046	Human Mouse Fly
tac1	tachykinin 1	0.046
uts1	urotensin 1	0.046
dzip1	DAZ interacting protein 1	0.046
khdrbs1a	KH domain containing, RNA binding, signal transduction associated 1a	0.045	Human Mouse
arl4ab	ADP-ribosylation factor-like 4ab	0.045
si:ch211-235f6.2	si:ch211-235f6.2	0.045
hlxb9lb	homeo box HB9 like b	0.045
vcana	versican a	0.045
nlgn4b	neuroligin 4b	0.045
prrx1a	paired related homeobox 1a	0.045	Mouse
rtn1a	reticulon 1a	0.045
kbp	kif1-binding protein	0.045
atp6v1h	ATPase, H+ transporting, lysosomal, V1 subunit H	0.044
ndr1	nodal-related 1	0.044
acsl4a	acyl-CoA synthetase long-chain family member 4a	0.044
slc1a2b	solute carrier family 1 (glial high affinity glutamate transporter), member 2b	0.044
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.044
pdgfaa	platelet-derived growth factor alpha a	0.044	Human
smu1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)	0.044
sox7	SRY-box containing gene 7	0.044
prmt8b	protein arginine methyltransferase 8b	0.043
hs2st1a	heparan sulfate 2-O-sulfotransferase 1a	0.043
pabpc1a	poly A binding protein, cytoplasmic 1 a	0.043
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.043	Zebrafish Mouse Rat
plk2b	polo-like kinase 2b (Drosophila)	0.043
atp6v1c1b	ATPase, H+ transporting, lysosomal, V1 subunit C, isoform 1b	0.043
esr1	estrogen receptor 1	0.043	Human Rat
cdh1	cadherin 1, epithelial	0.042	Human
ckbb	creatine kinase, brain b	0.042
sp2	sp2 transcription factor	0.042
map2k4a	mitogen-activated protein kinase kinase 4a	0.042
mstnb	myostatin b	0.042
ndrg1	N-myc downstream regulated gene 1	0.042
nrg2b	neuregulin 2b	0.042
colec11	collectin sub-family member 11	0.042
elk4	ELK4, ETS-domain protein	0.042
prkcea	protein kinase C, epsilon a	0.042	Mouse
aplp2	amyloid beta (A4) precursor-like protein 2	0.042
nf1b	neurofibromin 1b	0.042	Mouse
sox11b	SRY-box containing gene 11b	0.042
ehd2	EH-domain containing 2	0.041
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.041
itm2bb	integral membrane protein 2Bb	0.041
prom1b	prominin 1 b	0.041
lass2	LAG1 homolog, ceramide synthase 2 (S. cerevisiae)	0.041
sox17	SRY-box containing gene 17	0.041
postn	periostin, osteoblast specific factor	0.041
metrn	meteorin, glial cell differentiation regulator	0.041
LOC556849	ectonucleoside triphosphate diphosphohydrolase 5-like	0.041
ache	acetylcholinesterase	0.041
pdcd2	programmed cell death 2	0.040
il6st	interleukin 6 signal transducer	0.040	Human
gata5	GATA-binding protein 5	0.040
hbae1	hemoglobin alpha embryonic-1	0.040
lamc1	laminin, gamma 1	0.040
rer1	RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)	0.040
gcga	glucagon a and glucagon a-like	0.040
smad9	MAD homolog 9 (Drosophila)	0.040
rxrbb	retinoid x receptor, beta b	0.040
smoc1	SPARC related modular calcium binding 1	0.040
junbl	jun B proto-oncogene, like	0.040
mdm2	transformed 3T3 cell double minute 2 homolog (mouse)	0.039
cluap1	clusterin associated protein 1	0.039
si:dkeyp-110g5.2	si:dkeyp-110g5.2	0.039
copa	coatomer protein complex, subunit alpha	0.039
lama4	laminin, alpha 4	0.039
ved	ventrally expressed dharma/bozozok antagonist	0.039
eif4e1c	eukaryotic translation initiation factor 4E family member 1c	0.039
pmp22a	peripheral myelin protein 22a	0.039
sox19a	SRY-box containing gene 19a	0.039
nanos3	nanos homolog 3	0.039
per3	period homolog 3 (Drosophila)	0.039
zgc:92027	zgc:92027	0.039
c11orf2	c11orf2 homolog (H. sapiens)	0.039
supt5h	suppressor of Ty 5 homolog (S. cerevisiae)	0.039
atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.038
plekhh1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	0.038
ythdf1	YTH domain family, member 1	0.038
msna	moesin a	0.038
tlr2	toll-like receptor 2	0.038
unc5c	unc-5 homolog C (C. elegans)	0.038
erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog	0.038	Human Rat
gulp1	GULP, engulfment adaptor PTB domain containing 1	0.038
prkaa1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.038
col5a1	procollagen, type V, alpha 1	0.038
fbn2b	fibrillin 2b	0.038
isl2b	islet2b	0.038
scn8aa	sodium channel, voltage-gated, type VIII, alpha a	0.037
itga3b	integrin, alpha 3b	0.037
crsp6	cofactor required for Sp1 transcriptional activation, subunit 6	0.037
fras1	Fraser syndrome 1	0.037
rxrba	retinoid x receptor, beta a	0.037
her6	hairy-related 6	0.037
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.037	Fly
mxa	myxovirus (influenza) resistance A	0.037
nrp1a	neuropilin 1a	0.037	Mouse
stm	starmaker	0.037
cldn15la	claudin 15-like a	0.037
hspa5	heat shock protein 5	0.037
creb3l3l	cAMP responsive element binding protein 3-like 3 like	0.037
lamb1a	laminin, beta 1a	0.037
sass6	spindle assembly 6 homolog (C. elegans)	0.037
comta	catechol-O-methyltransferase a	0.037
nr6a1a	nuclear receptor subfamily 6, group A, member 1a	0.037
lhcgr	luteinizing hormone/choriogonadotropin receptor	0.037	Mouse Rat
hmgb2a	high-mobility group box 2a	0.037
rlbp1a	retinaldehyde binding protein 1a	0.037
dmrt3a	doublesex and mab-3 related transcription factor 3a	0.037
tnfa	tumor necrosis factor a (TNF superfamily, member 2)	0.037	Zebrafish Mouse Rat
tfap2a	transcription factor AP-2 alpha	0.037
pdcd6	programmed cell death 6	0.036
fgfrl1a	fibroblast growth factor receptor-like 1a	0.036
zgc:91910	zgc:91910	0.036
plagl2	pleiomorphic adenoma gene-like 2	0.036
foxi3a	forkhead box I3a	0.036
appa	amyloid beta (A4) precursor protein a	0.036
insrb	insulin receptor b	0.036	Human
shmt2	serine hydroxymethyltransferase 2 (mitochondrial)	0.036
cry2a	cryptochrome 2a	0.036
LOC796298	isotocin receptor-like 1	0.036
cplx2l	complexin 2, like	0.036
mchr1a	melanin-concentrating hormone receptor 1a	0.035
adrb2b	adrenergic receptor, beta 2b	0.035
dkk2	dickkopf homolog 2 (Xenopus laevis)	0.035
cct8	chaperonin containing TCP1, subunit 8 (theta)	0.035
zgc:77060	zgc:77060	0.035
tgfb1a	transforming growth factor, beta 1a	0.035	Human Fly
LOC565839	tumor necrosis factor alpha-induced protein 2-like	0.035
mycbp2	MYC binding protein 2	0.035
ncam2	neural cell adhesion molecule 2	0.035
si:ch211-241e15.2	si:ch211-241e15.2	0.035
rap2c	RAP2C, member of RAS oncogene family	0.035
cacna1da	calcium channel, voltage-dependent, L type, alpha 1D subunit, a	0.035
sb:cb472	sb:cb472	0.034
dynlrb1	dynein, light chain, roadblock-type 1	0.034
jun	jun proto-oncogene	0.034
clic4	chloride intracellular channel 4	0.034
mvp	major vault protein	0.034
gli3	GLI-Kruppel family member GLI3	0.034
lhx1b	LIM homeobox 1b	0.034
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.034	Zebrafish Rat
zgc:66382	zgc:66382	0.034
oprd1a	opioid receptor, delta 1a	0.034
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.034	Human Mouse
smox	spermine oxidase	0.034
aldh1a3	aldehyde dehydrogenase 1 family, member A3	0.034
mapk8b	mitogen-activated protein kinase 8b	0.034	Mouse
nlgn2a	neuroligin 2a	0.034
emx1	empty spiracles homeobox 1	0.034
s1pr2	sphingosine-1-phosphate receptor 2	0.033
tspan7b	tetraspanin 7b	0.033
zgc:64115	zgc:64115	0.033
midn	midnolin	0.033
sec23a	Sec23 homolog A (S. cerevisiae)	0.033
zgc:86598	zgc:86598	0.033	Human Fly
cpla2	cytosolic phospholipase a2	0.033
fzd5	frizzled homolog 5	0.033	Mouse
insm1a	insulinoma-associated 1a	0.033
LOC100001530	isotocin receptor-like 2	0.033
tlr9	toll-like receptor 9	0.033
mapta	microtubule-associated protein tau a	0.033
sh3gl1b	SH3-domain GRB2-like 1b	0.033
fbp1b	fructose-1,6-bisphosphatase 1b	0.033
rock2a	rho-associated, coiled-coil containing protein kinase 2a	0.033
ankrd6	ankyrin repeat domain 6	0.033
arntl1b	aryl hydrocarbon receptor nuclear translocator-like 1b	0.032	Mouse
eif3c	eukaryotic translation initiation factor 3, subunit C	0.032
stat1a	signal transduction and activation of transcription 1a	0.032
gng3	guanine nucleotide binding protein (G protein), gamma 3	0.032
si:dkeyp-22b2.3	si:dkeyp-22b2.3	0.032
sh3pxd2b	SH3 and PX domains 2B	0.032
ar	androgen receptor	0.032
gad1b	glutamate decarboxylase 1b	0.032
ube2d1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.032
scn1bb	sodium channel, voltage-gated, type I, beta b	0.032
tp53	tumor protein p53	0.032	Human Fly
guca1c	guanylate cyclase activator 1C	0.032
nfkbiaa	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a	0.032
kirrelb	kin of IRRE like b	0.032
nudc	nuclear distribution gene C homolog	0.032
ephb4b	eph receptor B4b	0.032
lifrb	leukemia inhibitory factor receptor alpha b	0.032
rxraa	retinoid X receptor, alpha a	0.031
ntrk2b	neurotrophic tyrosine kinase, receptor, type 2b	0.031	Mouse Rat
mical3	flavoprotein oxidoreductase MICAL3	0.031
cyp17a1	cytochrome P450, family 17, subfamily A, polypeptide 1	0.031
cyp19a1b	cytochrome P450, family 19, subfamily A, polypeptide 1b	0.031
pitpnb	phosphotidylinositol transfer protein, beta	0.031
inhbab	inhibin, beta Ab	0.031	Human
slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.031
phox2b	paired-like homeobox 2b	0.031
pou1f1	POU domain, class 1, transcription factor 1	0.031
wu:fv91b12	wu:fv91b12	0.031
rtn4rl2b	reticulon 4 receptor-like 2b	0.031
raraa	retinoic acid receptor, alpha a	0.031
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.031
proc	protein C (inactivator of coagulation factors Va and VIIIa)	0.030
twist1a	twist1a	0.030
calrl	calreticulin like	0.030
thbs1	thrombospondin 1	0.030	Human Mouse
ywhaqa	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a	0.030	Fly
crb2b	crumbs homolog 2b	0.030
zgc:101606	zgc:101606	0.030
ctsk	cathepsin K	0.030
btg2	B-cell translocation gene 2	0.030
relt	RELT tumor necrosis factor receptor	0.030
cyp26b1	cytochrome P450, family 26, subfamily b, polypeptide 1	0.030
mknk2b	MAP kinase-interacting serine/threonine kinase 2b	0.030
lgals3l	lectin, galactoside-binding, soluble, 3 (galectin 3)-like	0.030
cenph	centromere protein H	0.030
limk1	LIM domain kinase 1	0.030
s100v2	S100 calcium binding protein V2	0.030	Human
zgc:113210	zgc:113210	0.030
jag2	jagged 2	0.030
hs3st1l1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1-like1	0.030
card14	caspase recruitment domain family, member 14	0.030
col5a2l	collagen, type V, alpha 2-like	0.030
cry4	cryptochrome 4	0.030
sema3fb	semaphorin 3fb	0.030
ifnphi1	interferon phi 1	0.030
pdcd10a	programmed cell death 10a	0.029	Human
traf6	TNF receptor-associated factor 6	0.029	Human Mouse
pafah1b1a	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a	0.029	Mouse
arcn1	archain 1	0.029
traf4a	tnf receptor-associated factor 4a	0.029	Fly
lin28a	lin-28 homolog A (C. elegans)	0.029
sult3st1	sulfotransferase family 3, cytosolic sulfotransferase 1	0.029
bmp8a	bone morphogenetic protein 8a	0.029	Zebrafish Mouse
stab2	stabilin 2	0.029
nr2f5	nuclear receptor subfamily 2, group F, member 5	0.029
LOC100003330	melanocortin-2 receptor accessory protein 2-like	0.029
hnrpl	heterogeneous nuclear ribonucleoprotein L	0.029
myo7aa	myosin VIIAa	0.029
cdkn1a	cyclin-dependent kinase inhibitor 1A	0.029
zgc:56326	zgc:56326	0.029
traf3ip1	TNF receptor-associated factor 3 interacting protein 1	0.029
ntrk3b	neurotrophic tyrosine kinase, receptor, type 3b	0.029
lfng	lunatic fringe homolog	0.029	Mouse
nrarpa	notch-regulated ankyrin repeat protein a	0.029
trim13	tripartite motif-containing 13	0.028
ctnnb1	catenin (cadherin-associated protein), beta 1	0.028	Mouse
dedd1	death effector domain-containing 1	0.028
scinlb	scinderin like b	0.028
zmat2	zinc finger, matrin type 2	0.028
cntn1a	contactin 1a	0.028
ptrfb	polymerase I and transcript release factor b	0.028
LOC100000500	sclerostin-like	0.028
zgc:153997	zgc:153997	0.028
vox	ventral homeobox	0.028
snai1a	snail homolog 1a (Drosophila)	0.028
smo	smoothened homolog (Drosophila)	0.028
wnt16	wingless-type MMTV integration site family, member 16	0.028
ppm1aa	protein phosphatase, Mg2+/Mn2+ dependent, 1Aa	0.028	Human
stard3	START domain containing 3	0.028
jazf1b	JAZF zinc finger 1b	0.028
ptprb	protein tyrosine phosphatase, receptor type, b	0.028
pacsin3	protein kinase C and casein kinase substrate in neurons 3	0.028
zgc:91860	zgc:91860	0.028
si:ch211-124e16.1	si:ch211-124e16.1	0.028
rx3	retinal homeobox gene 3	0.028
opn1lw1	opsin 1 (cone pigments), long-wave-sensitive, 1	0.028
usp4	ubiquitin specific protease 4 (proto-oncogene)	0.028
cat	catalase	0.028	Mouse
flt1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.028	Human Rat Fly
ext1c	exostoses (multiple) 1c	0.027
pax9	paired box gene 9	0.027
si:ch73-60e21.1	si:ch73-60e21.1	0.027
zgc:161969	zgc:161969	0.027
mcl1a	myeloid cell leukemia sequence 1a	0.027	Human Mouse
wu:fb80a07	wu:fb80a07	0.027
olig4	oligodendrocyte transcription factor 4	0.027
loxl2b	lysyl oxidase-like 2b	0.027
foxg1a	forkhead box G1a	0.027
coro1a	coronin, actin binding protein, 1A	0.027
plod2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.027
chmp4b	chromatin modifying protein 4B	0.027
usp9	ubiquitin specific peptidase 9	0.027
phospho1	phosphatase, orphan 1	0.027
cdk8	cyclin-dependent kinase 8	0.027
ppp2cb	protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform	0.027	Fly
zgc:63840	zgc:63840	0.027
ube2na	ubiquitin-conjugating enzyme E2Na	0.027	Human Fly
inhbb	inhibin, beta B	0.027	Human Mouse
slc6a4b	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4B	0.027
wdr45l	wdr45 like	0.027
LOC567131	calcitonin gene-related peptide type 1 receptor-like	0.027
aldh2a	aldehyde dehydrogenase 2 family (mitochondrial)a	0.027
pak1	p21/Cdc42/Rac1-activated kinase 1	0.027
zgc:112986	zgc:112986	0.027
igfbp5a	insulin-like growth factor binding protein 5a	0.027	Mouse
tgm2b	transglutaminase 2b	0.026
rasgef1ba	RasGEF domain family, member 1Ba	0.026
hsd17b1	hydroxysteroid (17-beta) dehydrogenase 1	0.026
cyp1a	cytochrome P450, family 1, subfamily A	0.026
nkx6.2	NK6 transcription factor related, locus 2	0.026
phc2	polyhomeotic-like 2 (Drosophila)	0.026
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.026	Mouse
sqstm1	sequestosome 1	0.026
rab3c	RAB3C, member RAS oncogene family	0.026
fmnl2a	formin-like 2a	0.026
lmbr1l	limb region 1 like	0.026
nfe2l3	nuclear factor (erythroid-derived 2)-like 3	0.026
lama2	laminin, alpha 2	0.026	Mouse
notch2	notch homolog 2	0.026	Human Mouse Fly
zgc:85975	zgc:85975	0.026
faf1	Fas associated factor 1	0.026	Mouse
crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.026	Fly
fes	feline sarcoma oncogene	0.026
lndc1	ly6/neurotoxin domain containing 1	0.026
gmds	GDP-mannose 4,6-dehydratase	0.026
pklr	pyruvate kinase, liver and RBC	0.026
mospd1	motile sperm domain containing 1	0.026
akirin2	akirin 2	0.026
ahsg	alpha-2-HS-glycoprotein	0.026
calm3b	calmodulin 3b (phosphorylase kinase, delta)	0.026
esyt3	extended synaptotagmin-like protein 3	0.026
islr2	immunoglobulin superfamily containing leucine-rich repeat 2	0.026
k31	k31 gene	0.026
dlb	deltaB	0.025
paqr8	progestin and adipoQ receptor family member VIII	0.025
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.025
vtg3	vitellogenin 3, phosvitinless	0.025
tfap2b	transcription factor AP-2 beta	0.025
zgc:110586	zgc:110586	0.025
LOC100359374	BCL-WAV	0.025
otx5	orthodenticle homolog 5	0.025
wls	wntless homolog (Drosophila)	0.025	Fly
rag2	recombination activating gene 2	0.025
als2cr4a	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4a	0.025
papolb	poly(A) polymerase beta (testis specific)	0.025
meis1	myeloid ecotropic viral integration 1	0.025
ros1	v-ros UR2 sarcoma virus oncogene homolog 1 (avian)	0.025
men1	multiple endocrine neoplasia type 1 and multiple endocrine neoplasia I	0.025
mta2	metastasis associated 1 family, member 2	0.025
pax7b	paired box gene 7b	0.025
mcl1b	myeloid cell leukemia sequence 1b	0.025	Human Mouse
ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.025
pigu	phosphatidylinositol glycan anchor biosynthesis, class U	0.025
nort	notch-regulated transcript	0.025
gadd45ab	growth arrest and DNA-damage-inducible, alpha, b	0.025	Human
arl5c	ADP-ribosylation factor-like 5C	0.025
elovl1b	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1b	0.025
notum3	notum 3	0.025
spata2	spermatogenesis associated 2	0.025
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.025
esrrga	estrogen-related receptor gamma a	0.025
efnb3b	ephrin B3b	0.025
npepps	aminopeptidase puromycin sensitive	0.025
angptl1	angiopoietin-like 1	0.025
slc12a2	solute carrier family 12 (potassium/chloride transporters), member 2	0.025
dacha	dachshund a	0.025
gmnn	geminin, DNA replication inhibitor	0.025
rspo1	R-spondin homolog (Xenopus laevis)	0.025	Human Mouse
gng12a	guanine nucleotide binding protein (G protein), gamma 12a	0.025
pcdh2ac	protocadherin 2 alpha c	0.024
chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc binding protein 1	0.024
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.024
grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.024
tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.024
paqr7b	progestin and adipoQ receptor family member VII, b	0.024
her8a	hairy-related 8a	0.024
cp	ceruloplasmin	0.024
klfd	Kruppel-like factor d	0.024
matn4	matrilin 4	0.024
tcf12	transcription factor 12	0.024
dao.2	D-amino-acid oxidase 2	0.024
spred1	sprouty-related, EVH1 domain containing 1	0.024	Mouse
cahz	carbonic anhydrase	0.024	Mouse
hs6st1b	heparan sulfate 6-O-sulfotransferase 1b	0.024
plag1	pleiomorphic adenoma gene 1	0.024
zgc:101071	zgc:101071	0.024
ofd1	oral-facial-digital syndrome 1	0.024
nme2b.1	non-metastatic cells 2b.1, protein (NM23B) expressed in	0.024
sdc2	syndecan 2	0.024
tm4sf4	transmembrane 4 L six family member 4	0.024
efnb1	ephrin B1	0.024
foxb1.2	forkhead box B1.2	0.024
hs6st1a	heparan sulfate 6-O-sulfotransferase 1a	0.024
hmx4	H6 family homeobox 4	0.024
fzd8b	frizzled homolog 8b	0.024	Mouse
dtng	dystrobrevin, gamma and dystrobrevin, gamma-like	0.024	Worm
numbl	numb homolog (Drosophila)-like	0.024	Worm
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.024
ncor1	nuclear receptor co-repressor 1	0.024
emx2	empty spiracles homeobox 2	0.024