IMP: Integrative Multi-species Prediction

Danio rerio

3 genes annotated in zebrafish

Multi-species View

negative regulation of mrna metabolic process

GO:1903312

Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process.

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Known genes in the process in zebrafishInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of mrna metabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of mrna metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
anp32b	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	0.384
khdrbs1a	KH domain containing, RNA binding, signal transduction associated 1a	0.368
si:dkey-250d21.1	si:dkey-250d21.1	0.322
nhp2	NHP2 ribonucleoprotein homolog (yeast)	0.203
sf3b4	splicing factor 3b, subunit 4	0.198
ssb	Sjogren syndrome antigen B (autoantigen La)	0.138
snrpc	small nuclear ribonucleoprotein polypeptide C	0.096
ybx1	Y box binding protein 1	0.085
srsf11	serine/arginine-rich splicing factor 11	0.079
prpf39	PRP39 pre-mRNA processing factor 39 homolog (yeast)	0.078
snrnp70	small nuclear ribonucleoprotein 70 (U1)	0.077
zgc:86598	zgc:86598	0.076
cx43.4	connexin 43.4	0.069
snrpb	small nuclear ribonucleoprotein polypeptides B and B1	0.067
hmga1a	high mobility group AT-hook 1a	0.062
zgc:92194	zgc:92194	0.049
polr2b	polymerase (RNA) II (DNA directed) polypeptide B	0.049
hnrnpa0	heterogeneous nuclear ribonucleoprotein A0	0.048
hnrnpm	heterogeneous nuclear ribonucleoprotein M	0.048
eef2b	eukaryotic translation elongation factor 2b	0.048
setb	SET translocation (myeloid leukemia-associated) B	0.046
ilf3b	interleukin enhancer binding factor 3b	0.045
ctnnb1	catenin (cadherin-associated protein), beta 1	0.044
ck2b	casein kinase 2 beta	0.044
zgc:112425	zgc:112425	0.043
celsr1a	cadherin EGF LAG seven-pass G-type receptor 1a	0.043
huwe1	HECT, UBA and WWE domain containing 1	0.041
si:dkey-67c22.2	si:dkey-67c22.2	0.039
sumo3a	SMT3 suppressor of mif two 3 homolog 3a	0.037
kpnb1	karyopherin (importin) beta 1	0.037
prpf8	pre-mRNA processing factor 8	0.037
snrpd3l	small nuclear ribonucleoprotein D3 polypeptide, like	0.035
matr3l	matrin 3-like	0.033
cpsf6	cleavage and polyadenylation specific factor 6	0.031
LOC560606	novel protein similar to human and mouse leishmanolysin-like (metallopeptidase M8 family) (LMLN)	0.031
sf1	splicing factor 1	0.031
srsf1a	serine/arginine-rich splicing factor 1a	0.030
glra4a	glycine receptor, alpha 4a	0.029
zgc:64040	zgc:64040	0.029
rbm39a	RNA binding motif protein 39a	0.029
nrxn1a	neurexin 1a	0.029
yap1	Yes-associated protein 1	0.028
pes	pescadillo	0.028
ran	ras-related nuclear protein	0.027
nucks1a	nuclear casein kinase and cyclin-dependent kinase substrate 1a	0.026
ddx39b	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39b	0.026
ewsr1b	Ewing sarcoma breakpoint region 1b	0.026
safb	scaffold attachment factor B	0.025
ftsj	FtsJ homolog 3 (E. coli)	0.025
zgc:136930	zgc:136930	0.025
rbmx	RNA binding motif protein, X-linked	0.025	Rat
zgc:158363	zgc:158363	0.024
npm4	nucleophosmin/nucleoplasmin, 4	0.024	Mouse
h2afvl	H2A histone family, member V, like	0.024
zgc:77407	zgc:77407	0.023
slc43a1a	solute carrier family 43, member 1a	0.023
luc7l	LUC7-like (S. cerevisiae)	0.023
ilf2	interleukin enhancer binding factor 2	0.022
erf	Ets2 repressor factor	0.022
lsm14ab	LSM14 homolog Ab (SCD6, S. cerevisiae)	0.022
mtr	5-methyltetrahydrofolate-homocysteine methyltransferase	0.021
cherp	calcium homeostasis endoplasmic reticulum protein	0.021
zgc:110682	zgc:110682	0.021
foxc1a	forkhead box C1a	0.021
nolc1	nucleolar and coiled-body phosphoprotein 1	0.021
alas2	aminolevulinate, delta-, synthetase 2	0.020
srsf2	serine/arginine-rich splicing factor 2	0.020
akap8l	A kinase (PRKA) anchor protein 8-like	0.020
rtn1a	reticulon 1a	0.020
eif4ebp3l	eukaryotic translation initiation factor 4E binding protein 3, like	0.020
gatad2a	GATA zinc finger domain containing 2A	0.020
ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	0.020
caprin1a	cell cycle associated protein 1a	0.019
ddx39aa	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa	0.019
eftud2	elongation factor Tu GTP binding domain containing 2	0.019
rplp0	ribosomal protein, large, P0	0.019
mthfd1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent)	0.019
wu:fb58e05	wu:fb58e05	0.019
rbm4.2	RNA binding motif protein 4.2	0.019
pa2g4a	proliferation-associated 2G4, a	0.018
nupl1	nucleoporin like 1	0.018
ldb1b	LIM-domain binding factor 1b	0.018
zgc:66100	zgc:66100	0.018
rpl3	ribosomal protein L3	0.018
adssl	adenylosuccinate synthase, like	0.018
smu1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)	0.018
zgc:77262	zgc:77262	0.018
actn4	actinin, alpha 4	0.018
wnt3	wingless-type MMTV integration site family, member 3	0.018
srsf5a	serine/arginine-rich splicing factor 5a	0.018
nr2f6a	nuclear receptor subfamily 2, group F, member 6a	0.017
fancb	Fanconi anemia, complementation group B	0.017
sept8a	septin 8a	0.017
ranbp1	RAN binding protein 1	0.017
puf60a	poly-U binding splicing factor a	0.017
abcg2c	ATP-binding cassette, sub-family G (WHITE), member 2c	0.017
slc30a4	solute carrier family 30 (zinc transporter), member 4	0.017
polr3gla	polymerase (RNA) III (DNA directed) polypeptide G like a	0.017
rer1	RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)	0.017
vamp3	vesicle-associated membrane protein 3 (cellubrevin)	0.017
hnrnph1l	heterogeneous nuclear ribonucleoprotein H1, like	0.016
acsl1	acyl-CoA synthetase long-chain family member 1	0.016
si:dkey-261h17.1	si:dkey-261h17.1	0.016
fance	Fanconi anemia, complementation group E	0.016
wu:fb63c04	wu:fb63c04	0.016
cdkn1a	cyclin-dependent kinase inhibitor 1A	0.016
e2f4	E2F transcription factor 4	0.016
pomt2	protein-O-mannosyltransferase 2	0.015
arid4a	AT rich interactive domain 4A (RBP1-like)	0.015
ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.015
LOC570775	protein argonaute-1-like	0.015
npm1	nucleophosmin 1	0.015	Mouse
hs3st1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	0.015
zgc:77155	zgc:77155	0.015
otop1	otopetrin 1	0.015
zc3h10	zinc finger CCCH-type containing 10	0.015
zgc:77052	zgc:77052	0.015
abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.015
celf1	cugbp, Elav-like family member 1	0.015
fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.015
srrm1	serine/arginine repetitive matrix 1	0.014
ncl	nucleolin	0.014
notch3	notch homolog 3	0.014
zff9	zinc finger protein 9	0.014
zgc:153894	zgc:153894	0.014
arpc5a	actin related protein 2/3 complex, subunit 5A	0.014
slc39a11	solute carrier family 39 (metal ion transporter), member 11	0.014
senp3a	SUMO1/sentrin/SMT3 specific peptidase 3a	0.014
u2af1	U2(RNU2) small nuclear RNA auxiliary factor 1	0.014
rnd3a	Rho family GTPase 3a	0.014
atf4b1	activating transcription factor 4b1 (tax-responsive enhancer element B67)	0.014
mll4b	myeloid/lymphoid or mixed-lineage leukemia 4b	0.014
stau2	staufen, RNA binding protein, homolog 2 (Drosophila)	0.014
ctnna	catenin (cadherin-associated protein), alpha	0.014
zgc:92611	zgc:92611	0.014
zmat2	zinc finger, matrin type 2	0.014
LOC100148274	hypothetical protein LOC100148274	0.014
foxd5	forkhead box D5	0.014
cad	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	0.013
phf2	PHD finger protein 2	0.013
nat10	N-acetyltransferase 10	0.013
ppat	phosphoribosyl pyrophosphate amidotransferase	0.013
cnot1	CCR4-NOT transcription complex, subunit 1	0.013
nktr	natural killer-tumor recognition sequence	0.013
trim71	tripartite motif-containing 71	0.013
hmgb2b	high-mobility group box 2b	0.013
sf3b5	splicing factor 3b, subunit 5	0.013
mtm1	myotubularin 1	0.013
pcp4l1	Purkinje cell protein 4 like 1	0.013
si:dkey-205h13.2	si:dkey-205h13.2	0.013
zgc:63840	zgc:63840	0.013
hnrpl	heterogeneous nuclear ribonucleoprotein L	0.013
LOC563749	hypothetical protein LOC563749	0.013
dnttip2	deoxynucleotidyltransferase, terminal, interacting protein 2	0.013
fanca	Fanconi anemia, complementation group A	0.013
zgc:162431	zgc:162431	0.013
slc30a6	solute carrier family 30 (zinc transporter), member 6	0.013
nrxn3a	neurexin 3a	0.013
zgc:92745	zgc:92745	0.013
pbx4	pre-B-cell leukemia transcription factor 4	0.013
si:dkey-236e20.6	si:dkey-236e20.6	0.013
rrp12	ribosomal RNA processing 12 homolog (S. cerevisiae)	0.013
cstf1	cleavage stimulation factor, 3' pre-RNA, subunit 1	0.013
eif4bb	eukaryotic translation initiation factor 4Bb	0.013
api5	apoptosis inhibitor 5	0.013
pabpc4	poly(A) binding protein, cytoplasmic 4 (inducible form)	0.012
spon1a	spondin 1a	0.012
scamp2	secretory carrier membrane protein 2	0.012
rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.012
il7r	interleukin 7 receptor	0.012
spred1	sprouty-related, EVH1 domain containing 1	0.012
rc3	rabconnectin 3	0.012
sf3a1	splicing factor 3a, subunit 1	0.012
ube2nb	ubiquitin-conjugating enzyme E2Nb	0.012
kpnb3	karyopherin (importin) beta 3	0.012
rtf1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.012
mllt10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	0.012
si:ch211-197h24.9	si:ch211-197h24.9	0.012
si:ch211-57k11.10	si:ch211-57k11.10	0.012
rfc2	replication factor C (activator 1) 2	0.012
stk11	serine/threonine kinase 11	0.012
snrpd1	small nuclear ribonucleoprotein D1 polypeptide	0.012
ext1c	exostoses (multiple) 1c	0.012
ogt.1	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 1	0.012
lycat	lysocardiolipin acyltransferase	0.012
zgc:110380	zgc:110380	0.011
zgc:63569	zgc:63569	0.011
zgc:56010	zgc:56010	0.011
ttc28	tetratricopeptide repeat domain 28	0.011
gtpbp4	GTP binding protein 4	0.011
map2k4b	mitogen-activated protein kinase kinase 4b	0.011
nrp2b	neuropilin 2b	0.011
kdm1a	lysine (K)-specific demethylase 1a	0.011
setdb2	SET domain, bifurcated 2	0.011
ube2i2	ubiquitin-conjugating enzyme E2I2	0.011
ogt.2	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 2	0.011
eif2c3	eukaryotic translation initiation factor 2C, 3	0.011
sart1	squamous cell carcinoma antigen recognised by T cells	0.011
glud1b	glutamate dehydrogenase 1b	0.011
si:dkeyp-51f11.8	si:dkeyp-51f11.8	0.011
abcg2a	ATP-binding cassette, sub-family G (WHITE), member 2a	0.011
ddx18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18	0.011
si:ch211-216l23.2	si:ch211-216l23.2	0.011
si:ch211-203h15.1	si:ch211-203h15.1	0.011
ankrd13c	ankyrin repeat domain 13C	0.011
faf1	Fas associated factor 1	0.011
srm	spermidine synthase	0.011
wu:fi04f09	wu:fi04f09	0.011
sf3a2	splicing factor 3a, subunit 2	0.011
brd3a	bromodomain containing 3a	0.011
graspl	GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein like	0.011
zgc:123326	zgc:123326	0.011
kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1	0.011
wu:fj68a07	wu:fj68a07	0.011
dip2c	DIP2 disco-interacting protein 2 homolog C (Drosophila)	0.011
ctcf	CCCTC-binding factor (zinc finger protein)	0.011
si:ch211-51e12.7	si:ch211-51e12.7	0.011
rbbp6	retinoblastoma binding protein 6	0.011
rpsa	ribosomal protein SA	0.011
nap1l1	nucleosome assembly protein 1, like 1	0.011
grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.011
glcci1	glucocorticoid induced transcript 1	0.011
dvl2	dishevelled, dsh homolog 2 (Drosophila)	0.011
waca	WW domain containing adaptor with coiled-coil a	0.011
hspd1	heat shock 60kD protein 1 (chaperonin)	0.010
dbt	dihydrolipoamide branched chain transacylase E2	0.010
stmn1a	stathmin 1a	0.010
eya4	eyes absent homolog 4 (Drosophila)	0.010
aldh7a1	aldehyde dehydrogenase 7 family, member A1	0.010
LOC100006043	Kruppel-like factor 5-like	0.010
cpsf2	cleavage and polyadenylation specific factor 2	0.010
stxbp6l	syntaxin binding protein 6 (amisyn), like	0.010
trdmt1	tRNA aspartic acid methyltransferase 1	0.010
traf3	TNF receptor-associated factor 3	0.010
ahcy	S-adenosylhomocysteine hydrolase	0.010
si:dkey-222f8.3	si:dkey-222f8.3	0.010
slc25a3b	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b	0.010
crip2	cysteine-rich protein 2	0.010
tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.010
pabpc1a	poly A binding protein, cytoplasmic 1 a	0.010	Human
slc30a9	solute carrier family 30 (zinc transporter), member 9	0.010
macf1	microtubule-actin crosslinking factor 1	0.010
ldb2b	LIM-domain binding factor 2b	0.010