IMP: Integrative Multi-species Prediction

Danio rerio

1 genes annotated in zebrafish

macroautophagy

The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane-bounded autophagic bodies which are then degraded within the lysosome (or vacuole). Though once thought to be a purely non-selective process, it appears that some types of macroautophagy, e.g. macropexophagy, macromitophagy, may involve selective targeting of the targets to be degraded.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "macroautophagy"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "macroautophagy" (in gray)

Name	Description	Probability	Func Analog Organism
igf1rb	insulin-like growth factor 1b receptor	0.588	Worm
ndr1	nodal-related 1	0.312
creb3l3l	cAMP responsive element binding protein 3-like 3 like	0.247
tp73	tumor protein p73	0.245	Fly
sdf4	stromal cell derived factor 4	0.244
gro2	groucho 2	0.217
tm9sf2	transmembrane 9 superfamily member 2	0.191
zbtb4	zinc finger and BTB domain containing 4	0.188
rab2a	RAB2A, member RAS oncogene family	0.164
odc1	ornithine decarboxylase 1	0.155
hhex	hematopoietically expressed homeobox	0.146
apg3l	APG3 autophagy 3-like	0.140	Mouse
npc1	Niemann-Pick disease, type C1	0.138
lrrc6	leucine rich repeat containing 6	0.110
pou5f1	POU domain, class 5, transcription factor 1	0.108
ntla	no tail a	0.102
mapk14a	mitogen-activated protein kinase 14a	0.093
brd2a	bromodomain-containing 2a	0.092
nras	neuroblastoma RAS viral (v-ras) oncogene homolog	0.087	Fly
cftr	cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)	0.086
dvl3	dishevelled, dsh homolog 3 (Drosophila)	0.081
baxa	bcl2-associated X protein, a	0.077
ap2a1	adaptor-related protein complex 2, alpha 1 subunit	0.075
syap1	synapse associated protein 1	0.074
fuca2	fucosidase, alpha-L- 2, plasma	0.074
flh	floating head	0.072
adrb2b	adrenergic receptor, beta 2b	0.071
nup50	nucleoporin 50	0.070
hgfb	hepatocyte growth factor b	0.070
grnb	granulin b	0.068
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.068
tpd52l2b	tumor protein D52-like 2b	0.068
clcn7	chloride channel 7	0.067
insrb	insulin receptor b	0.066	Worm
ext2	exostoses (multiple) 2	0.066
ptk2.1	protein tyrosine kinase 2a	0.066
smyd3	SET and MYND domain containing 3	0.065
zgc:112430	zgc:112430	0.064
met	met proto-oncogene (hepatocyte growth factor receptor)	0.063
rpl15	ribosomal protein L15	0.063
furinb	furin (paired basic amino acid cleaving enzyme) b	0.063
rab5aa	RAB5A, member RAS oncogene family, a	0.061
tsga14	testis specific, 14	0.060
tax1bp1b	Tax1 (human T-cell leukemia virus type I) binding protein 1b	0.060
vdra	vitamin D receptor a	0.059
zgc:92606	zgc:92606	0.058
atp6v1f	ATPase, H+ transporting, V1 subunit F	0.058
kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.057
atp6v1c1a	ATPase, H+ transporting, lysosomal, V1 subunit C, isoform 1a	0.057
yipf4	Yip1 domain family, member 4	0.057
arcn1l	archain 1 like	0.057
sox9b	SRY-box containing gene 9b	0.057
rpsa	ribosomal protein SA	0.056
fzd5	frizzled homolog 5	0.055
atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	0.055
furina	furin (paired basic amino acid cleaving enzyme) a	0.054
pafah1b1a	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a	0.053
crsp7	cofactor required for Sp1 transcriptional activation, subunit 7	0.053
grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.053
mbnl2	muscleblind-like 2 (Drosophila)	0.052
myl9	myosin, light polypeptide 9, regulatory	0.052
ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.051
fermt2	fermitin family homolog 2 (Drosophila)	0.050
brca2	breast cancer 2, early onset	0.050
adipor1a	adiponectin receptor 1a	0.049
wipi1	WD repeat domain, phosphoinositide interacting 1	0.049	Fly
add1	adducin 1 (alpha)	0.049
pdxdc1	pyridoxal-dependent decarboxylase domain containing 1	0.049
mbtps1	membrane-bound transcription factor protease, site 1	0.048
zgc:56596	zgc:56596	0.048
ush1c	Usher syndrome 1C (autosomal recessive, severe)	0.048
rhoaa	ras homolog gene family, member Aa	0.047
zgc:66100	zgc:66100	0.047
ppardb	peroxisome proliferator-activated receptor delta b	0.047
ap1m2	adaptor-related protein complex 1, mu 2 subunit	0.047
limk2	LIM domain kinase 2	0.047
fgf3	fibroblast growth factor 3	0.047
rab1a	RAB1A, member RAS oncogene family	0.046	Human
dvl2	dishevelled, dsh homolog 2 (Drosophila)	0.046
si:dkey-108d22.4	si:dkey-108d22.4	0.046
bcl2	B-cell leukemia/lymphoma 2	0.046
h1m	linker histone H1M	0.045
acsl4a	acyl-CoA synthetase long-chain family member 4a	0.045
slc17a8	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8	0.045
zgc:73134	zgc:73134	0.045
ca15b	carbonic anhydrase XV b	0.045
glcci1	glucocorticoid induced transcript 1	0.045
mpp6b	membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)	0.045
wipi2	WD repeat domain, phosphoinositide interacting 2	0.044
mapk4	mitogen-activated protein kinase 4	0.044
rab7	RAB7, member RAS oncogene family	0.044	Human
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.044
zgc:66317	zgc:66317	0.043
ndfip1	Nedd4 family interacting protein 1	0.043
pias4a	protein inhibitor of activated STAT, 4a	0.043
zgc:56272	zgc:56272	0.043
cluap1	clusterin associated protein 1	0.043
LOC100006043	Kruppel-like factor 5-like	0.043
lsm12	LSM12 homolog (S. cerevisiae)	0.043
trappc5	trafficking protein particle complex 5	0.043
gpia	glucose phosphate isomerase a	0.043
tnrc5	trinucleotide repeat containing 5	0.043
rnf41	ring finger protein 41	0.042
atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.042
pop7	processing of precursor 7, ribonuclease P family	0.042
ppp2cb	protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform	0.042
trim13	tripartite motif-containing 13	0.042
si:dkeyp-84f11.5	si:dkeyp-84f11.5	0.041
acsl1	acyl-CoA synthetase long-chain family member 1	0.041
si:dkey-15j16.2	si:dkey-15j16.2	0.041
ptena	phosphatase and tensin homolog A	0.041
spns1	spinster homolog 1 (Drosophila)	0.040
zgc:114045	zgc:114045	0.040
rnf2	ring finger protein 2	0.040
map9	microtubule-associated protein 9	0.040
stxbp2	syntaxin binding protein 2	0.040
zgc:100787	zgc:100787	0.039
cpped1	calcineurin-like phosphoesterase domain containing 1	0.039
zgc:175214	zgc:175214	0.039
tbx1	T-box 1	0.039
ctbs	chitobiase, di-N-acetyl-	0.039
zgc:56010	zgc:56010	0.039
cdh1	cadherin 1, epithelial	0.039
spsb4a	splA/ryanodine receptor domain and SOCS box containing 4a	0.039
dram2	DNA-damage regulated autophagy modulator 2	0.039
zgc:55558	zgc:55558	0.039	Fly
calua	calumenin a	0.038
bida	BH3 interacting domain death agonist	0.038
cry3	cryptochrome 3	0.038
sf3b1	splicing factor 3b, subunit 1	0.038
slc25a32a	solute carrier family 25, member 32a	0.038
mapk3	mitogen-activated protein kinase 3	0.038	Fly
si:dkey-145p14.5	si:dkey-145p14.5	0.038
cldn12	claudin 12	0.037
cyb5r3	cytochrome b5 reductase 3	0.037
zgc:77849	zgc:77849	0.037
plcd1b	phospholipase C, delta 1b	0.037
igf1	insulin-like growth factor 1	0.036
ldhd	lactate dehydrogenase D	0.036
rps2	ribosomal protein S2	0.036
cecr1a	cat eye syndrome chromosome region, candidate 1a	0.036
adipor1b	adiponectin receptor 1b	0.036
derl1	Der1-like domain family, member 1	0.035
ppm1k	protein phosphatase 1K (PP2C domain containing)	0.035
psmb5	proteasome (prosome, macropain) subunit, beta type, 5	0.035
ccnt2a	cyclin T2a	0.035
copz2	zeta2-cop	0.035
traf6	TNF receptor-associated factor 6	0.035
kcmf1	potassium channel modulatory factor 1	0.035
zgc:92111	zgc:92111	0.035
camk2g1	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1	0.035
nrg2a	neuregulin 2a	0.035
sirt2	sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)	0.034
tfe3a	transcription factor binding to IGHM enhancer 3a	0.034
angptl1	angiopoietin-like 1	0.034
faf2	Fas associated factor family member 2	0.034
s1pr3	sphingosine-1-phosphate receptor 3	0.033
ptpn11b	protein tyrosine phosphatase, non-receptor type 11, b	0.033
pak2a	p21 (CDKN1A)-activated kinase 2a	0.033
slc26a5	solute carrier family 26, member 5	0.033
got1	glutamic-oxaloacetic transaminase 1, soluble	0.033
prkar1aa	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a	0.033
ck2b	casein kinase 2 beta	0.033
capn2a	calpain 2, (m/II) large subunit a	0.033
dusp6	dual specificity phosphatase 6	0.033
rpl23	ribosomal protein L23	0.032
dync1li1	dynein, cytoplasmic 1, light intermediate chain 1	0.032
vps33b	vacuolar protein sorting 33B	0.032
kop	askopos	0.032
ikbkg	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.032
cyp24a1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.032
dlg1	discs, large (Drosophila) homolog 1	0.032
tbpl2	TATA box binding protein like 2	0.032
mmp15a	matrix metallopeptidase 15a	0.032
naa15b	N(alpha)-acetyltransferase 15, NatA auxiliary subunit b	0.032
numbl	numb homolog (Drosophila)-like	0.032
pygb	phosphorylase, glycogen; brain	0.032
capn1a	calpain 1, (mu/I) large subunit a	0.031
ghrl	ghrelin/obestatin preprohormone	0.031
map1lc3b	microtubule-associated protein 1 light chain 3 beta	0.031
foxi1	forkhead box I1	0.031
ccnh	cyclin H	0.031
ctnnd2a	catenin (cadherin-associated protein), delta 2a	0.031
baxb	bcl2-associated X protein, b	0.031
shha	sonic hedgehog a	0.031
arl6	ADP-ribosylation factor-like 6	0.031
foxf1	forkhead box F1	0.031
smu1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)	0.030
pi4k2a	phosphatidylinositol 4-kinase type 2 alpha	0.030
scin	scinderin	0.030
kif5bb	kinesin family member 5B, b	0.030
zgc:193933	zgc:193933	0.030
wdr45	WD repeat domain 45	0.030
vps35	vacuolar protein sorting 35 (yeast)	0.030
fam3c	family with sequence similarity 3, member C	0.030
tjp2a	tight junction protein 2a (zona occludens 2)	0.030
gata1a	GATA binding protein 1a	0.030
arvcfb	armadillo repeat gene deleted in velocardiofacial syndrome b	0.030
rab13	RAB13, member RAS oncogene family	0.030
rmnd5b	required for meiotic nuclear division 5 homolog B (S. cerevisiae)	0.030
kdm5c	lysine (K)-specific demethylase 5C	0.030
nkx2.3	NK2 transcription factor related 3	0.030
ctnnd1	catenin (cadherin-associated protein), delta 1	0.029
LOC100537975	thyroid receptor-interacting protein 11-like	0.029
ccz1	CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)	0.029
slc2a10	solute carrier family 2 (facilitated glucose transporter), member 10	0.029
ptpn13	protein tyrosine phosphatase, non-receptor type 13	0.029
gabarapa	GABA(A) receptor-associated protein a	0.029
thrb	thyroid hormone receptor beta	0.029
maff	v-maf musculoaponeurotic fibrosarcoma oncogene homolog f (avian)	0.029
bsdc1	BSD domain containing 1	0.029
crfb13	cytokine receptor family member b13	0.029
lsr	lipolysis stimulated lipoprotein receptor	0.029
spty2d1	SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)	0.029
gro1	groucho 1	0.029
LOC561662	Golgi phosphoprotein 3-like	0.028
zgc:114140	zgc:114140	0.028
fam76b	family with sequence similarity 76, member B	0.028
c11orf2	c11orf2 homolog (H. sapiens)	0.028
ca4a	carbonic anhydrase IV a	0.028
stac3	SH3 and cysteine rich domain 3	0.028
LOC559569	egl nine homolog 2-like	0.028
zgc:114043	zgc:114043	0.028
mxi1	max interacting protein	0.028
cldn15a	claudin 15a	0.028
csad	cysteine sulfinic acid decarboxylase	0.028
zgc:92489	zgc:92489	0.028
galcb	galactosylceramidase b	0.028
atl1	atlastin GTPase 1	0.027
si:ch211-1n9.7	si:ch211-1n9.7	0.027
stard3	START domain containing 3	0.027
kidins220b	kinase D-interacting substrate of 220b	0.027
btk	Bruton agammaglobulinemia tyrosine kinase	0.027
ggnbp2	gametogenetin binding protein 2	0.027
snx6	sorting nexin 6	0.027
nr3c2	nuclear receptor subfamily 3, group C, member 2	0.027
csnk1g2a	casein kinase 1, gamma 2a	0.027
tmem106a	transmembrane protein 106A	0.027
map4k5	mitogen-activated protein kinase kinase kinase kinase 5	0.027
sri	sorcin	0.027
ankrd12	ankyrin repeat domain 12	0.027
zgc:63992	zgc:63992	0.027
pgrmc2	progesterone receptor membrane component 2	0.027
insra	insulin receptor a	0.027	Worm
camk2n1a	calcium/calmodulin-dependent protein kinase II inhibitor 1a	0.027
prkca	protein kinase C, alpha	0.027
anxa5a	annexin A5a	0.027
si:dkey-162b3.1	si:dkey-162b3.1	0.027
bbc3	BCL2 binding component 3	0.027
snx4	sorting nexin 4	0.027	Yeast
acsl3b	acyl-CoA synthetase long-chain family member 3b	0.027
ptdss1	phosphatidylserine synthase 1	0.027
ncoa2	nuclear receptor coactivator 2	0.027
rictor	RPTOR independent companion of MTOR, complex 2	0.027
si:dkey-3d4.3	si:dkey-3d4.3	0.027
rps16	ribosomal protein S16	0.027
zgc:64098	zgc:64098	0.026
LOC565106	novel protein similar to vertebrate calpain 1 (CAPN1)	0.026
fancd2	Fanconi anemia, complementation group D2	0.026
map2k4a	mitogen-activated protein kinase kinase 4a	0.026
rhobtb2a	Rho-related BTB domain containing 2a	0.026
polb	polymerase (DNA directed), beta	0.026
slc35e1	solute carrier family 35, member E1	0.026
dnaja2l	DnaJ (Hsp40) homolog, subfamily A, member 2, like	0.026
ralgapa1	Ral GTPase activating protein, alpha subunit 1 (catalytic)	0.026
per2	period homolog 2 (Drosophila)	0.026
prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.026
zgc:66242	zgc:66242	0.026
tbp	TATA box binding protein	0.026
klhl11	kelch-like 11 (Drosophila)	0.026
cops6	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)	0.026
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.026
tyrobp	TYRO protein tyrosine kinase binding protein	0.026
map2k7	mitogen-activated protein kinase kinase 7	0.026
mtdha	metadherin a	0.026
mitfa	microphthalmia-associated transcription factor a	0.026
vipr1	vasoactive intestinal peptide receptor 1	0.026
stau1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.026
sas	sarcoma amplified sequence	0.025
zgc:64042	zgc:64042	0.025
chid1	chitinase domain containing 1	0.025
ube2i	ubiquitin-conjugating enzyme E2I	0.025
pafah1b3	platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit	0.025
klf11b	Kruppel-like factor 11b	0.025
pdcd2	programmed cell death 2	0.025
ulk1b	unc-51-like kinase 1b (C. elegans)	0.025
nrbf2	nuclear receptor binding factor 2	0.025
LOC561889	granulito	0.025
tm9sf3	transmembrane 9 superfamily member 3	0.025
wu:fa04h02	wu:fa04h02	0.025
als2b	amyotrophic lateral sclerosis 2b (juvenile)	0.025
nos2b	nitric oxide synthase 2b, inducible	0.025
max	myc-associated factor X	0.025
usp10	ubiquitin specific peptidase 10	0.024
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.024
LOC566479	novel protein similar to H.sapiens PLCH1, phospholipase C, eta 1 (PLCH1)	0.024
tsc1a	tuberous sclerosis 1a	0.024
cd40	CD40 antigen	0.024
kif3b	kinesin family member 3B	0.024
abcc4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	0.024
ldb1a	LIM-domain binding factor 1a	0.024
ptger4b	prostaglandin E receptor 4 (subtype EP4) b	0.024
zgc:103471	zgc:103471	0.024
pik3r4	phosphoinositide-3-kinase, regulatory subunit 4	0.024
capns1b	calpain, small subunit 1 b	0.024
ctsf	cathepsin F	0.024
ccnl1	cyclin L1	0.024
slc15a2	solute carrier family 15 (H+/peptide transporter), member 2	0.024
zgc:66313	zgc:66313	0.024
napa	N-ethylmaleimide sensitive fusion protein attachment protein alpha	0.024
adipoql	adiponectin, C1Q and collagen domain containing, like	0.024
arf2	ADP-ribosylation factor 2	0.024
arpc5a	actin related protein 2/3 complex, subunit 5A	0.024
fbxo32	F-box protein 32	0.024
tbc1d15	TBC1 domain family, member 15	0.024
fbxo16	F-box protein 16	0.024
adrb2a	adrenergic receptor, beta 2a	0.024
vipar	vps33b interacting protein, apical-basolateral polarity regulator	0.024
synj1	synaptojanin 1	0.024
rela	v-rel reticuloendotheliosis viral oncogene homolog A	0.024
slc9a5	solute carrier family 9 (sodium/hydrogen exchanger), member 5	0.024
kcnn1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	0.024
dusp4	dual specificity phosphatase 4	0.023
stk35l	serine/threonine kinase 35, like	0.023
mapk7	mitogen-activated protein kinase 7	0.023
tspan7b	tetraspanin 7b	0.023
si:dkey-273o13.1	si:dkey-273o13.1	0.023
zgc:55573	zgc:55573	0.023
fbxw11a	F-box and WD-40 domain protein 11a	0.023
zmynd11	zinc finger, MYND domain containing 11	0.023
zgc:110605	zgc:110605	0.023
serinc2	serine incorporator 2	0.023
pcmtd1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	0.023
aldh2a	aldehyde dehydrogenase 2 family (mitochondrial)a	0.023
copb1	coatomer protein complex, subunit beta 1	0.023
atg9b	ATG9 autophagy related 9 homolog B (S. cerevisiae)	0.023
traf3	TNF receptor-associated factor 3	0.023
ttc39c	tetratricopeptide repeat domain 39C	0.023
ugt5b1	UDP glucuronosyltransferase 5 family, polypeptide B1	0.023
med7	mediator complex subunit 7	0.023
me3	malic enzyme 3, NADP(+)-dependent, mitochondrial	0.023
rfx6	regulatory factor X, 6	0.023
arl13b	ADP-ribosylation factor-like 13b	0.023
e2f5	E2F transcription factor 5	0.023
arrdc1b	arrestin domain containing 1b	0.023
ptpra	protein tyrosine phosphatase, receptor type, A	0.023
mnx1	motor neuron and pancreas homeobox 1	0.023
thraa	thyroid hormone receptor alpha a	0.023
LOC559616	calcium-binding protein 1-like	0.023
fbxl14b	F-box and leucine-rich repeat protein 14b	0.023
ap3s2	adaptor-related protein complex 3, sigma 2 subunit	0.023
g6pd	glucose-6-phosphate dehydrogenase	0.023
wdfy2	WD repeat and FYVE domain containing 2	0.023
thrap6	thyroid hormone receptor associated protein 6	0.023
yipf3	Yip1 domain family, member 3	0.023
lrrc4ba	leucine rich repeat containing 4Ba	0.023
bactin1	bactin1	0.023
eif3hb	eukaryotic translation initiation factor 3, subunit H, b	0.023
illr4	immune-related, lectin-like receptor 4	0.023
nr1d2b	nuclear receptor subfamily 1, group D, member 2b	0.023
cyp11a1	cytochrome P450, subfamily XIA, polypeptide 1	0.023
serinc1	serine incorporator 1	0.023
pgpep1	pyroglutamyl-peptidase I	0.023
atp6v1ba	ATPase, H+ transporting, lysosomal, V1 subunit B, member a	0.023
epas1b	endothelial PAS domain protein 1b	0.023
hlxb9la	homeo box HB9 like a	0.022
ctsd	cathepsin D	0.022
wu:fa18f11	wu:fa18f11	0.022
dvr1	decapentaplegic and Vg-related 1	0.022
zgc:92139	zgc:92139	0.022
zgc:63569	zgc:63569	0.022
wars	tryptophanyl-tRNA synthetase	0.022
cnih2	cornichon homolog 2 (Drosophila)	0.022
gnb5a	guanine nucleotide binding protein (G protein), beta 5a	0.022
tbc1d16	TBC1 domain family, member 16	0.022
zgc:56676	zgc:56676	0.022
axin1	axin 1	0.022
fut10	fucosyltransferase 10	0.022
trappc4	trafficking protein particle complex 4	0.022
im:7150937	im:7150937	0.022
mical3	flavoprotein oxidoreductase MICAL3	0.022
st3gal5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	0.022
cyp3c4	cytochrome P450, family 3, subfamily C, polypeptide 4	0.022
zgc:110800	zgc:110800	0.022
agps	alkylglycerone phosphate synthase	0.022
si:ch211-287j19.6	si:ch211-287j19.6	0.022
zeb2a	zinc finger E-box binding homeobox 2a	0.022
syncripl	synaptotagmin binding, cytoplasmic RNA interacting protein, like	0.022
pcdh1a4	protocadherin 1 alpha 4	0.022
LOC100001530	isotocin receptor-like 2	0.022
bactin2	bactin2	0.022
yth2	YTH domain family 2	0.022
fut8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	0.022
snx1	sorting nexin 1	0.022
slc4a11	solute carrier family 4, sodium borate transporter, member 11	0.022
pldn	pallidin homolog (mouse)	0.022
abcg2c	ATP-binding cassette, sub-family G (WHITE), member 2c	0.022
LOC100149353	transient receptor potential cation channel subfamily M member 6-like	0.022
rwdd3	RWD domain containing 3	0.022
rpe65b	retinal pigment epithelium-specific protein 65b	0.022
ap3d1	adaptor-related protein complex 3, delta 1 subunit	0.022
tpst1l	tyrosylprotein sulfotransferase 1, like	0.022
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.022
stk17b	serine/threonine kinase 17b (apoptosis-inducing)	0.022
suv420h2	suppressor of variegation 4-20 homolog 2 (Drosophila)	0.022
si:ch73-178d14.1	si:ch73-178d14.1	0.022
ugt5a5	UDP glucuronosyltransferase 5 family, polypeptide A5	0.022
zgc:63629	zgc:63629	0.022
atg4a	ATG4 autophagy related 4 homolog A (S. cerevisiae)	0.022
efcab7	EF-hand calcium binding domain 7	0.022
fmo5	flavin containing monooxygenase 5	0.022
stx8	syntaxin 8	0.022
il6st	interleukin 6 signal transducer	0.022
mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.022	Mouse Fly
zgc:101572	zgc:101572	0.022
nxt2	nuclear transport factor 2-like export factor 2	0.021
rpl37	ribosomal protein L37	0.021
ugt2a3	UDP glucuronosyltransferase 2 family, polypeptide A3	0.021
f2r	coagulation factor II (thrombin) receptor	0.021
rnf103	ring finger protein 103	0.021
akt2	v-akt murine thymoma viral oncogene homolog 2	0.021
ada	adenosine deaminase	0.021
LOC568356	actin filament-associated protein 1-like	0.021
nos2a	nitric oxide synthase 2a, inducible	0.021
wnt5a	wingless-type MMTV integration site family, member 5a	0.021
slc30a5	solute carrier family 30 (zinc transporter), member 5	0.021
zgc:73264	zgc:73264	0.021
zgc:153646	zgc:153646	0.021
nfasca	neurofascin homolog (chicken) a	0.021
kbp	kif1-binding protein	0.021
cul2	cullin 2	0.021
arf5	ADP-ribosylation factor 5	0.021
lycat	lysocardiolipin acyltransferase	0.021
myt1	myelin transcription factor 1	0.021
ift46	intraflagellar transport protein 46	0.021
zgc:162420	zgc:162420	0.021
eif4g2a	eukaryotic translation initiation factor 4, gamma 2a	0.021
cry1b	cryptochrome 1b	0.021
prkcsh	protein kinase C substrate 80K-H	0.021
uba1	ubiquitin-like modifier activating enzyme 1	0.021
kcnip1b	Kv channel interacting protein 1 b	0.021
ugt5c3	UDP glucuronosyltransferase 5 family, polypeptide C3	0.021
nap1l4b	nucleosome assembly protein 1-like 4b	0.021
cradd	CASP2 and RIPK1 domain containing adaptor with death domain	0.021
btbd2	BTB (POZ) domain containing 2	0.021
prlrb	prolactin receptor b	0.021
xrn2	5'-3' exoribonuclease 2	0.021
wasa	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a	0.021
rrm2b	ribonucleotide reductase M2 b	0.021
sgcb	sarcoglycan, beta (dystrophin-associated glycoprotein)	0.021
hif1aa	hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a	0.021
casrl	calcium-sensing receptor, like	0.021
ero1l	ERO1-like (S. cerevisiae)	0.021
pdk3a	pyruvate dehydrogenase kinase, isozyme 3a	0.021
nitr4a	novel immune-type receptor 4a	0.021
prlra	prolactin receptor a	0.021
gnal	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	0.021
git2b	G protein-coupled receptor kinase interactor 2b	0.021
arpc4l	actin related protein 2/3 complex, subunit 4, like	0.021
LOC566040	protein notum homolog	0.020
spag1	sperm associated antigen 1	0.020
ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.020
rab24	RAB24, member RAS oncogene family	0.020
aqp9b	aquaporin 9b	0.020
ifnphi3	interferon phi 3	0.020
ccr6a	chemokine (C-C motif) receptor 6a	0.020
lepb	leptin b	0.020
xpo7	exportin 7	0.020
zgc:112317	zgc:112317	0.020
ap3m2	adaptor-related protein complex 3, mu 2 subunit	0.020
tmem115	transmembrane protein 115	0.020
ube2d1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.020
crb2a	crumbs homolog 2a	0.020
anxa4	annexin A4	0.020
nucb2b	nucleobindin 2b	0.020
mtm1	myotubularin 1	0.020
nup107	nucleoporin 107	0.020
sppl2	signal peptide peptidase-like 2	0.020
si:dkey-13i19.7	si:dkey-13i19.7	0.020
sb:eu385	sb:eu385	0.020
rps6kal	ribosomal protein S6 kinase, like	0.020
grip2l	glutamate receptor interacting protein 2-like	0.020
glra1	glycine receptor, alpha 1	0.020
si:dkey-220f10.6	si:dkey-220f10.6	0.020
hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.020
zgc:85910	zgc:85910	0.020
aldh4a1	aldehyde dehydrogenase 4 family, member A1	0.020
abca5	ATP-binding cassette, sub-family A (ABC1), member 5	0.020
ccdc151	coiled-coil domain containing 151	0.020
zgc:114097	zgc:114097	0.020
ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.020
acot11a	acyl-CoA thioesterase 11a	0.020
slc25a37	solute carrier family 25, member 37	0.020
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.020
pld1a	phospholipase D1a	0.020
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.020
atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.020
si:dkeyp-115d2.5	si:dkeyp-115d2.5	0.020
apip	APAF1 interacting protein	0.020
map2k4b	mitogen-activated protein kinase kinase 4b	0.020
zgc:101722	zgc:101722	0.020
phf20b	PHD finger protein 20, b	0.020
atp6v0a1a	ATPase, H+ transporting, lysosomal V0 subunit a isoform 1a	0.020
ap3m1	adaptor-related protein complex 3, mu 1 subunit	0.020
cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.020
LOC796298	isotocin receptor-like 1	0.020
hpse	heparanase	0.020
syne2b	spectrin repeat containing, nuclear envelope 2b	0.020
zgc:101761	zgc:101761	0.020
zgc:112356	zgc:112356	0.020
strap	serine/threonine kinase receptor associated protein	0.020
cul4a	cullin 4A	0.020
abcc1	ATP-binding cassette, sub-family C, member 1	0.020
golt1b	golgi transport 1 homolog B (S. cerevisiae)	0.020
bmf1	Bcl2 modifying factor 1	0.020
march6	membrane-associated ring finger (C3HC4) 6	0.020
arntl1a	aryl hydrocarbon receptor nuclear translocator-like 1a	0.020
agpat9	1-acylglycerol-3-phosphate O-acyltransferase 9	0.020
dock4b	dedicator of cytokinesis 4b	0.020
cldne	claudin e	0.020
adpgk2	ADP-dependent glucokinase 2	0.020
im:7147988	im:7147988	0.020
unc50	unc-50 homolog (C. elegans)	0.020
sc:d0343	sc:d0343	0.020
adipor2	adiponectin receptor 2	0.020
abhd11	abhydrolase domain containing 11	0.020
per3	period homolog 3 (Drosophila)	0.019
aco1	aconitase 1, soluble	0.019
cul5a	cullin 5a	0.019
kcnj13	potassium inwardly-rectifying channel, subfamily J, member 13	0.019
ids	iduronate 2-sulfatase	0.019
zgc:112982	zgc:112982	0.019
picalml	phosphatidylinositol binding clathrin assembly protein, like	0.019
cd22	cd22 molecule	0.019
mtmr6	myotubularin related protein 6	0.019
zgc:162165	zgc:162165	0.019
si:dkey-194n13.2	si:dkey-194n13.2	0.019
med27	mediator complex subunit 27	0.019
LOC100334492	ectonucleoside triphosphate diphosphohydrolase 5-like	0.019
atf7a	activating transcription factor 7a	0.019
ccnt2b	cyclin T2b	0.019
cul1a	cullin 1a	0.019
zgc:56533	zgc:56533	0.019
zgc:100789	zgc:100789	0.019
sec23ip	SEC23 interacting protein	0.019
zgc:56068	zgc:56068	0.019
plaa	phospholipase A2-activating protein	0.019
LOC556082	calcium binding protein 7-like	0.019
nitr12	novel immune-type receptor 12	0.019
zgc:110112	zgc:110112	0.019
slc7a3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	0.019
zgc:91821	zgc:91821	0.019
mfn2	mitofusin 2	0.019
ext1a	exostoses (multiple) 1a	0.019
foxa	forkhead box A sequence	0.019
elf2a	E74-like factor 2a (ets domain transcription factor)	0.019
LOC560358	solute carrier family 2, facilitated glucose transporter member 11-like	0.019
adal	adenosine deaminase-like	0.019
xbp1	X-box binding protein 1	0.019
arhgef7a	Rho guanine nucleotide exchange factor (GEF) 7a	0.019
thoc1	THO complex 1	0.019
alx4a	aristaless-like homeobox 4a	0.019
slc2a15b	solute carrier family 2 (facilitated glucose transporter), member 15b	0.019
arpc5b	actin related protein 2/3 complex, subunit 5B	0.019
becn1	beclin 1 (coiled-coil, myosin-like BCL2 interacting protein)	0.019
tmem35	transmembrane protein 35	0.019
psmd11b	proteasome (prosome, macropain) 216S subunit, non-ATPase, 11b	0.019
ube2v2	ubiquitin-conjugating enzyme E2 variant 2	0.019
slc8a2b	solute carrier family 8 (sodium-calcium exchanger), member 2b	0.019
cldn15lb	claudin 15-like b	0.019
atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.019
zgc:113030	zgc:113030	0.019
zgc:154106	zgc:154106	0.019
golph3	golgi phosphoprotein 3	0.019
ugt5f1	UDP glucuronosyltransferase 5 family, polypeptide F1	0.019
igf2a	insulin-like growth factor 2a	0.019
capza1b	capping protein (actin filament) muscle Z-line, alpha 1b	0.019
renbp	renin binding protein	0.019
cpvl	carboxypeptidase, vitellogenic-like	0.019
epc2	enhancer of polycomb homolog 2 (Drosophila)	0.019
slc9a6b	solute carrier family 9 (sodium/hydrogen exchanger), member 6b	0.019
zmynd19	zinc finger, MYND domain containing 19	0.019
zgc:152785	zgc:152785	0.019
dlb	deltaB	0.019
ing3	inhibitor of growth family, member 3	0.019
rnf11	ring finger protein 11	0.019
zgc:114095	zgc:114095	0.019
cmtm4	CKLF-like MARVEL transmembrane domain containing 4	0.019
slco3a1	solute carrier organic anion transporter family, member 3A1	0.019
wwp2	WW domain containing E3 ubiquitin protein ligase 2	0.019
morn4	MORN repeat containing 4	0.019
fbxw11b	F-box and WD-40 domain protein 11b	0.019
frzb	frizzled-related protein	0.019
rhoh	ras homolog gene family, member H	0.018
orai1	ORAI calcium release-activated calcium modulator 1	0.018
pigk	phosphatidylinositol glycan, class K	0.018
jub	jub, ajuba homolog (Xenopus laevis)	0.018
tspan3b	tetraspanin 3b	0.018
arl8ba	ADP-ribosylation factor-like 8Ba	0.018
ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.018
si:dkeyp-51f11.8	si:dkeyp-51f11.8	0.018
syne2a	spectrin repeat containing, nuclear envelope 2a	0.018
si:dkey-175m17.8	si:dkey-175m17.8	0.018
actr10	actin-related protein 10 homolog (S. cerevisiae)	0.018
ms4a17a.4	membrane-spanning 4-domains, subfamily A, member 17A.4	0.018
tp53bp2	tumor protein p53 binding protein, 2	0.018
ophn1	oligophrenin 1	0.018
wu:fd61a05	wu:fd61a05	0.018
ckap5	cytoskeleton associated protein 5	0.018
dctn3	dynactin 3 (p22)	0.018
si:dkey-229b18.3	si:dkey-229b18.3	0.018
cdc16	cell division cycle 16 homolog (S. cerevisiae)	0.018
pik3c3	phosphoinositide-3-kinase, class 3	0.018
abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.018
bet1	blocked early in transport 1 homolog (S. cerevisiae)	0.018
hspb6	heat shock protein, alpha-crystallin-related, b6	0.018
slc38a6	solute carrier family 38, member 6	0.018
ptk2.2	protein tyrosine kinase 2b	0.018
dhdds	dehydrodolichyl diphosphate synthase	0.018
slc38a10	solute carrier family 38, member 10	0.018
zgc:91951	zgc:91951	0.018
prkcbp1l	protein kinase C binding protein 1, like	0.018
sh2d3cb	SH2 domain containing 3Cb	0.018
sp2	sp2 transcription factor	0.018
si:ch211-35n24.1	si:ch211-35n24.1	0.018
fbxw7	F-box and WD repeat domain containing 7	0.018
nme2b.1	non-metastatic cells 2b.1, protein (NM23B) expressed in	0.018
lin54	lin-54 homolog	0.018
prkcea	protein kinase C, epsilon a	0.018
bbox1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)	0.018
chmp5	chromatin modifying protein 5	0.018
lepa	leptin a	0.018
zgc:92417	zgc:92417	0.018
cd164	CD164 molecule, sialomucin	0.018
mmp24	matrix metallopeptidase 24	0.018
cltca	clathrin, heavy polypeptide a (Hc)	0.018
lypla1	lysophospholipase I	0.018
rtf1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.018
he2	hatching enzyme 2	0.018
rbpjb	recombination signal binding protein for immunoglobulin kappa J region b	0.018
zgc:114199	zgc:114199	0.018
zbtb2b	zinc finger and BTB domain containing 2b	0.018
gdf11	growth differentiation factor 11	0.018
si:dkey-261l7.3	si:dkey-261l7.3	0.018
sptlc1	serine palmitoyltransferase, long chain base subunit 1	0.018
ugt5b4	UDP glucuronosyltransferase 5 family, polypeptide B4	0.018
pcdh2g5	protocadherin 2 gamma 5	0.018
taf1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.018
cetn3	centrin 3	0.018
il10	interleukin 10	0.018
peli2	pellino homolog 2 (Drosophila)	0.018
exoc1	exocyst complex component 1	0.018
sbf1	SET binding factor 1	0.018
dusp22a	dual specificity phosphatase 22a	0.018
kcnc3a	potassium voltage-gated channel, Shaw-related subfamily, member 3a	0.018
jak2b	Janus kinase 2b	0.018
si:ch211-212d10.2	si:ch211-212d10.2	0.018
cdk8	cyclin-dependent kinase 8	0.018
kera	keratocan	0.018
opn3	opsin 3 (encephalopsin, panopsin)	0.018
smc1al	structural maintenance of chromosomes 1A, like	0.018
pnp5b	purine nucleoside phosphorylase 5b	0.018
n4bp2	NEDD4 binding protein 2	0.018
actr2b	ARP2 actin-related protein 2b homolog (yeast)	0.018
fmr1	fragile X mental retardation 1	0.018
zgc:63587	zgc:63587	0.018
mapk6	mitogen-activated protein kinase 6	0.018
wdfy1	WD repeat and FYVE domain containing 1	0.018
sec63	SEC63-like (S. cerevisiae)	0.018
hpse2	heparanase 2	0.018
dnajc28	DnaJ (Hsp40) homolog, subfamily C, member 28	0.018
metrn	meteorin, glial cell differentiation regulator	0.018
fkbp1ab	FK506 binding protein 1Ab	0.018
nprl2	nitrogen permease regulator-like 2 (S. cerevisiae)	0.018
arntl2	aryl hydrocarbon receptor nuclear translocator-like 2	0.018
zgc:92335	zgc:92335	0.018
fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.018
pigu	phosphatidylinositol glycan anchor biosynthesis, class U	0.018
ugt2a5	UDP glucuronosyltransferase 2 family, polypeptide A5	0.018
pik3r2	phosphoinositide-3-kinase, regulatory subunit, polypeptide 2	0.018
pex19	peroxisomal biogenesis factor 19	0.018
ubiad1	UbiA prenyltransferase domain containing 1	0.018
rab9a	RAB9A, member RAS oncogene family	0.018
zgc:101744	zgc:101744	0.018
maf1	MAF1 homolog (S. cerevisiae)	0.018
zgc:91861	zgc:91861	0.018
zgc:101855	zgc:101855	0.018
grk7b	G protein-coupled receptor kinase 7b	0.018
zgc:101566	zgc:101566	0.018
rock2a	rho-associated, coiled-coil containing protein kinase 2a	0.018
cdk20	cyclin-dependent kinase 20	0.018
zgc:171724	zgc:171724	0.018
tmem147	transmembrane protein 147	0.018
LOC794786	interferon-induced protein with tetratricopeptide repeats 1-like	0.018
pls3	plastin 3 (T isoform)	0.018
zgc:91985	zgc:91985	0.018
ppcdc	phosphopantothenoylcysteine decarboxylase	0.018
csrnp1a	cysteine-serine-rich nuclear protein 1a	0.017
hic1l	hypermethylated in cancer 1 like	0.017
pcdh2g1	protocadherin 2 gamma 1	0.017
clptm1l	cleft lip and palate associated transmembrane protein 1, like	0.017
cln6	ceroid-lipofuscinosis, neuronal 6, late infantile, variant	0.017
vps39	vacuolar protein sorting 39 homolog (S. cerevisiae)	0.017
LOC799612	prolactin 2	0.017
zgc:92873	zgc:92873	0.017
sft2d1	SFT2 domain containing 1	0.017
htatip	HIV-1 tat interactive protein, homolog (human)	0.017
ythdc1	YTH domain containing 1	0.017
gsk3b	glycogen synthase kinase 3 beta	0.017
lepr	leptin receptor	0.017
cog2	component of oligomeric golgi complex 2	0.017
ppapdc3	phosphatidic acid phosphatase type 2 domain containing 3	0.017
gosr1	golgi SNAP receptor complex member 1	0.017
npy2r	neuropeptide Y receptor Y2	0.017
sult1st5	sulfotransferase family 1, cytosolic sulfotransferase 5	0.017
fev	FEV (ETS oncogene family)	0.017
slc48a1a	solute carrier family 48 (heme transporter), member 1a	0.017
atp6v1h	ATPase, H+ transporting, lysosomal, V1 subunit H	0.017
zgc:153718	zgc:153718	0.017
pnpla7b	patatin-like phospholipase domain containing 7b	0.017
hgs	hepatocyte growth factor-regulated tyrosine kinase substrate	0.017
zgc:101035	zgc:101035	0.017
zdhhc15b	zinc finger, DHHC domain containing 15b	0.017
thy1	Thy-1 cell surface antigen	0.017
zgc:113380	zgc:113380	0.017
iqgap1	IQ motif containing GTPase activating protein 1	0.017
gatad1	GATA zinc finger domain containing 1	0.017
adcy5	adenylate cyclase 5	0.017
tmprss4a	transmembrane protease, serine 4a	0.017
yipf6	Yip1 domain family, member 6	0.017
laptm4b	lysosomal associated protein transmembrane 4 beta	0.017
tmem9b	TMEM9 domain family, member B	0.017
psmd3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.017
azin1a	antizyme inhibitor 1a	0.017
im:6894391	im:6894391	0.017
hps1	Hermansky-Pudlak syndrome 1	0.017
adam17a	a disintegrin and metalloproteinase domain 17a	0.017
kcnh2l	potassium voltage-gated channel, subfamily H (eag-related), member 2 like	0.017
zgc:55671	zgc:55671	0.017
inhbb	inhibin, beta B	0.017
ugt5b2	UDP glucuronosyltransferase 5 family, polypeptide B2	0.017
lss	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)	0.017
si:dkey-216e9.4	si:dkey-216e9.4	0.017
zgc:55413	zgc:55413	0.017
zgc:163064	zgc:163064	0.017
pcsk2	proprotein convertase subtilisin/kexin type 2	0.017
slc8a4a	solute carrier family 8 (sodium/calcium exchanger), member 4a	0.017
hprt1l	hypoxanthine phosphoribosyltransferase 1, like	0.017
foxo3a	forkhead box O3A	0.017	Fly
slc38a2	solute carrier family 38, member 2	0.017