IMP: Integrative Multi-species Prediction

Danio rerio

3 genes annotated in zebrafish

Multi-species View

regulation of extrinsic apoptotic signaling pathway

GO:2001236

Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of extrinsic apoptotic signaling pathway"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of extrinsic apoptotic signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
osr1	odd-skipped related 1 (Drosophila)	0.912
cmyb	transcription factor cmyb	0.891
kdrl	kinase insert domain receptor like	0.823
bcl2l1	bcl2-like 1	0.734
tnfrsfa	tumor necrosis factor receptor superfamily, member a	0.730
mcl1a	myeloid cell leukemia sequence 1a	0.683	Human
cav1	caveolin 1	0.650	Human
nrp1a	neuropilin 1a	0.607	Mouse
acvr2a	activin receptor IIa	0.490
matn4	matrilin 4	0.462
nrg2a	neuregulin 2a	0.454
fgfr1a	fibroblast growth factor receptor 1a	0.443	Mouse
cnn2	calponin 2	0.427
stc1l	stanniocalcin 1, like	0.421
mpx	myeloid-specific peroxidase	0.415
ntn2	netrin 2	0.413
ptgs1	prostaglandin-endoperoxide synthase 1	0.411
hoxa13a	homeo box A13a	0.406
baxa	bcl2-associated X protein, a	0.399	Mouse
runx1	runt-related transcription factor 1	0.372
mapk6	mitogen-activated protein kinase 6	0.367
hsd17b1	hydroxysteroid (17-beta) dehydrogenase 1	0.348
frem3	Fras1 related extracellular matrix 3	0.343
pcsk5a	proprotein convertase subtilisin/kexin type 5a	0.332
tbx22	T-box 22	0.327
efna5a	ephrin A5a	0.318
zgc:101724	zgc:101724	0.314
mdm2	transformed 3T3 cell double minute 2 homolog (mouse)	0.305
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.298
rag1	recombination activating gene 1	0.298
igf1ra	insulin-like growth factor 1a receptor	0.297
hmx2	H6 family homeobox 2	0.290
pitx3	paired-like homeodomain transcription factor 3	0.289
col4a2	collagen, type IV, alpha 2	0.283
ywhae1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1	0.281
hbae1	hemoglobin alpha embryonic-1	0.281
nrp2a	neuropilin 2a	0.281
wnt10a	wingless-type MMTV integration site family, member 10a	0.281
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.272
fgg	fibrinogen, gamma polypeptide	0.272
igf1	insulin-like growth factor 1	0.270
cntn2	contactin 2	0.267
aox3	aldehyde oxidase 3	0.262
met	met proto-oncogene (hepatocyte growth factor receptor)	0.260
mapk14a	mitogen-activated protein kinase 14a	0.256
tagln2	transgelin 2	0.250
fgfr1b	fibroblast growth factor receptor 1b	0.245	Mouse
fgfr3	fibroblast growth factor receptor 3	0.245
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.242
kita	kit receptor a	0.241
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.238
ifnphi1	interferon phi 1	0.235
igfbp1b	insulin-like growth factor binding protein 1b	0.232
sgk1	serum/glucocorticoid regulated kinase 1	0.230
ptprf	protein tyrosine phosphatase, receptor type, F	0.229
coro1a	coronin, actin binding protein, 1A	0.228
odc1	ornithine decarboxylase 1	0.225
pou1f1	POU domain, class 1, transcription factor 1	0.222
runx3	runt-related transcription factor 3	0.219	Mouse
nos1	nitric oxide synthase 1 (neuronal)	0.218
notch2	notch homolog 2	0.218
cyp24a1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.217
col11a1a	collagen, type XI, alpha 1a	0.211
gadd45aa	growth arrest and DNA-damage-inducible, alpha, a	0.210
col7a1l	collagen type VII alpha 1-like	0.209
csrnp1b	cysteine-serine-rich nuclear protein 1b	0.209
stmn2b	stathmin-like 2b	0.202
ywhai	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide	0.201
fn1	fibronectin 1	0.200
mcl1b	myeloid cell leukemia sequence 1b	0.195	Human
tgfb1a	transforming growth factor, beta 1a	0.193
apom	apolipoprotein M	0.193
myhz2	myosin, heavy polypeptide 2, fast muscle specific	0.190
mmp9	matrix metalloproteinase 9	0.186
zgc:110343	zgc:110343	0.185
mmp2	matrix metalloproteinase 2	0.185
sb:cb166	sb:cb166	0.183
six1b	sine oculis homeobox homolog 1b	0.181
elmo1	engulfment and cell motility 1 (ced-12 homolog, C. elegans)	0.181
lcp1	lymphocyte cytosolic plastin 1	0.178
fzd7b	frizzled homolog 7b	0.174
phox2b	paired-like homeobox 2b	0.170
plxnb2a	plexin b2a	0.169
hmgb2a	high-mobility group box 2a	0.168	Mouse
ptena	phosphatase and tensin homolog A	0.166
igf1rb	insulin-like growth factor 1b receptor	0.164
il1b	interleukin 1, beta and interleukin 1, beta	0.163	Human
atf3	activating transcription factor 3	0.163
ccz1	CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)	0.160
itgb3b	integrin beta 3b	0.159
gdf9	growth differentiation factor 9	0.157
alas2	aminolevulinate, delta-, synthetase 2	0.156
si:ch211-14k19.8	si:ch211-14k19.8	0.156
inha	inhibin, alpha	0.155
dct	dopachrome tautomerase	0.154
hbbe1.1	hemoglobin beta embryonic-1.1	0.153
wnt3	wingless-type MMTV integration site family, member 3	0.152
crh	corticotropin releasing hormone	0.151
chrna6	cholinergic receptor, nicotinic, alpha 6	0.149
abcf2	ATP-binding cassette, sub-family F (GCN20), member 2	0.148
ryk	receptor-like tyrosine kinase	0.147
mapk8b	mitogen-activated protein kinase 8b	0.146
stat3	signal transduction and activation of transcription 3	0.146
cyp3c1	cytochrome P450, family 3, subfamily c, polypeptide 1	0.144
notch3	notch homolog 3	0.143
foxe3	forkhead box E3	0.141
hspb9	heat shock protein, alpha-crystallin-related, 9	0.138
pax7b	paired box gene 7b	0.137
il7r	interleukin 7 receptor	0.136
fgf20a	fibroblast growth factor 20a	0.136
cpla2	cytosolic phospholipase a2	0.136
si:dkeyp-7c9.1	si:dkeyp-7c9.1	0.135
epha4a	eph receptor A4a	0.133
hspb6	heat shock protein, alpha-crystallin-related, b6	0.132
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.131
mmp13a	matrix metalloproteinase 13a	0.131
ntrk3b	neurotrophic tyrosine kinase, receptor, type 3b	0.130
mapk12	mitogen-activated protein kinase 12	0.129
cp	ceruloplasmin	0.128
nme2b.1	non-metastatic cells 2b.1, protein (NM23B) expressed in	0.127
fgf19	fibroblast growth factor 19	0.124
epb41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.122
metrnl	meteorin, glial cell differentiation regulator-like	0.122
sulf1	sulfatase 1	0.121
sema3d	semaphorin 3d	0.121
ggps1	geranylgeranyl diphosphate synthase 1	0.120
cdkn1a	cyclin-dependent kinase inhibitor 1A	0.120
hbbe3	hemoglobin beta embryonic-3	0.119
fgb	fibrinogen, B beta polypeptide	0.119
plg	plasminogen	0.119
naa50	N(alpha)-acetyltransferase 50, NatE catalytic subunit	0.117
inhbaa	inhibin, beta Aa	0.117	Human
twist2	twist2	0.117
rictor	RPTOR independent companion of MTOR, complex 2	0.116
mapk3	mitogen-activated protein kinase 3	0.116
sox2	SRY-box containing gene 2	0.115
flt4	fms-related tyrosine kinase 4	0.115
mobkl2a	MOB1, Mps One Binder kinase activator-like 2A (yeast)	0.115
wnt9b	wingless-type MMTV integration site family, member 9B	0.114
plekhh1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	0.114
hspa12b	heat shock protein 12B	0.113
jag1b	jagged 1b	0.113
fabp10a	fatty acid binding protein 10a, liver basic	0.113
lef1	lymphocyte enhancer binding factor 1	0.112
brd2b	bromodomain containing 2b	0.110
ildr1b	immunoglobulin-like domain containing receptor 1b	0.109
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.109
nadl1.2	neural adhesion molecule L1.2	0.109
brd4	bromodomain containing 4	0.108
lpp	LIM domain containing preferred translocation partner in lipoma	0.108
tnfa	tumor necrosis factor a (TNF superfamily, member 2)	0.108	Zebrafish
hif1ab	hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b	0.107
nfkbiaa	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a	0.106
nrg2b	neuregulin 2b	0.105
calm2a	calmodulin 2a (phosphorylase kinase, delta)	0.105
rbp4	retinol binding protein 4, plasma	0.104
hlxb9la	homeo box HB9 like a	0.104
ptgesl	prostaglandin E synthase 2-like	0.104
ywhabl	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like	0.104
scrt1a	scratch homolog 1, zinc finger protein a (Drosophila)	0.103
mxa	myxovirus (influenza) resistance A	0.102
hsp90b1	heat shock protein 90, beta (grp94), member 1	0.102
col4a6	collagen, type IV, alpha 6	0.101
star	steroidogenic acute regulatory protein	0.101
ecscr	endothelial cell-specific chemotaxis regulator	0.100
cxcl12a	chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)	0.100
cnih	cornichon homolog (Drosophila)	0.100
eif4a1b	eukaryotic translation initiation factor 4A, isoform 1B	0.100
bida	BH3 interacting domain death agonist	0.100
ins	preproinsulin	0.099
postn	periostin, osteoblast specific factor	0.098
sid4	secreted immunoglobulin domain 4	0.096
c9	complement component 9	0.096
jak1	Janus kinase 1	0.096
hlxb9lb	homeo box HB9 like b	0.095
dcn	decorin	0.095
kal1b	Kallmann syndrome 1b sequence	0.094
fgf3	fibroblast growth factor 3	0.094
actn1	actinin, alpha 1	0.093
spi1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.093
pcdh18b	protocadherin 18b	0.091
wu:fb80a07	wu:fb80a07	0.091
pak2a	p21 (CDKN1A)-activated kinase 2a	0.091	Human
fadd	Fas (tnfrsf6)-associated via death domain	0.090
adcyap1a	adenylate cyclase activating polypeptide 1a	0.090
uba1	ubiquitin-like modifier activating enzyme 1	0.090
brd2a	bromodomain-containing 2a	0.089
a2ml	alpha-2-macroglobulin-like	0.089
skia	nuclear oncoprotein skia	0.087
jazf1b	JAZF zinc finger 1b	0.087
LOC797331	novel protein similar to vertebrate solute carrier family 12, (potassium-chloride transporter) member 5 (SLC12A5)	0.087
nrarpa	notch-regulated ankyrin repeat protein a	0.086
lhx2b	LIM homeobox 2b	0.086
zgc:195154	zgc:195154	0.086
ptpn11a	protein tyrosine phosphatase, non-receptor type 11, a	0.085
slc6a4a	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4A	0.085
tjp1	tight junction protein 1 (zona occludens 1)	0.085
fgf10a	fibroblast growth factor 10a	0.085	Mouse
plxna4	plexin A4	0.085
prkcea	protein kinase C, epsilon a	0.084
lhcgr	luteinizing hormone/choriogonadotropin receptor	0.084
clock	clock	0.084
ctsl1a	cathepsin L, 1 a	0.083
cflar	CASP8 and FADD-like apoptosis regulator	0.083
lyz	lysozyme	0.083
hspb11	heat shock protein, alpha-crystallin-related, b11	0.082
ahcy	S-adenosylhomocysteine hydrolase	0.082
pob	partial optokinetic response b	0.082
sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.082
prdx4	peroxiredoxin 4	0.082
acvr2b	activin receptor IIb	0.081
tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.081
bhmt	betaine-homocysteine methyltransferase	0.081
prdx2	peroxiredoxin 2	0.081	Mouse
ripk2	receptor-interacting serine-threonine kinase 2	0.080
alad	aminolevulinate dehydratase	0.079
sema3aa	semaphorin 3aa	0.079
cyp2ad2	cytochrome P450, family 2, subfamily AD, polypeptide 2	0.079
cdkn1b	cyclin-dependent kinase inhibitor 1b (p27, kip1)	0.079
cald1	caldesmon 1	0.079
casc3	cancer susceptibility candidate 3	0.078
hoxc4a	homeo box C4a	0.078
plcg1	phospholipase C, gamma 1	0.077
bmf1	Bcl2 modifying factor 1	0.077
efnb2a	ephrin B2a	0.076
ptges	prostaglandin E synthase	0.076
cdh11	cadherin 11, osteoblast	0.076
dlx4a	distal-less homeobox gene 4a	0.076
ptger4a	prostaglandin E receptor 4 (subtype EP4) a	0.075
zgc:55572	zgc:55572	0.075
plekhg5a	pleckstrin homology domain containing, family G (with RhoGef domain) member 5a	0.075
il6r	interleukin 6 receptor	0.074
plaa	phospholipase A2-activating protein	0.074
slit3	slit (Drosophila) homolog 3	0.074
lhx6	LIM homeobox 6	0.073
col12a1	collagen, type XII, alpha 1	0.073
cyp1b1	cytochrome P450, family 1, subfamily B, polypeptide 1	0.072
fgfr2	fibroblast growth factor receptor 2	0.072
scrt1b	scratch homolog 1, zinc finger protein b (Drosophila)	0.072
hgfb	hepatocyte growth factor b	0.072
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.072
hcrt	hypocretin (orexin) neuropeptide precursor	0.072
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.072
pcsk5b	proprotein convertase subtilisin/kexin type 5b	0.072
col4a3	collagen, type IV, alpha 3	0.072
ambpl	alpha-1-microglobulin/bikunin precursor, like	0.071
cobl	cordon-bleu homolog (mouse)	0.071
hmx1	H6 homeo box 1	0.071
irf6	interferon regulatory factor 6	0.071
hoxa13b	homeo box A13b	0.071
adipor2	adiponectin receptor 2	0.071
rcc2	regulator of chromosome condensation 2	0.071
vgll4l	vestigial like 4 like	0.071
neo1	neogenin 1	0.070
csf3r	colony stimulating factor 3 receptor (granulocyte)	0.070
slit1a	slit homolog 1a (Drosophila)	0.070
ptmaa	prothymosin, alpha a	0.070
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.069
LOC566020	Gig2-like protein DreO	0.069
sumo3a	SMT3 suppressor of mif two 3 homolog 3a	0.069
yrk	Yes-related kinase	0.069
hfe2	hemochromatosis type 2	0.068
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.068
hug	HuG	0.068
furina	furin (paired basic amino acid cleaving enzyme) a	0.068
vegfab	vascular endothelial growth factor Ab	0.068	Mouse
efna2	ephrin A2	0.068
egr1	early growth response 1	0.068
cbr1l	carbonyl reductase 1-like	0.067
gclm	glutamate-cysteine ligase, modifier subunit	0.067	Mouse
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.067
stat1a	signal transduction and activation of transcription 1a	0.066
lrp5	low density lipoprotein receptor-related protein 5	0.066
naa35	N(alpha)-acetyltransferase 35, NatC auxiliary subunit	0.066
wif1	wnt inhibitory factor 1	0.066
mst1rb	macrophage stimulating 1 receptor (c-met-related tyrosine kinase), b	0.066
oc90	otoconin 90	0.065
grhl2b	grainyhead-like 2b (Drosophila)	0.065
LOC567131	calcitonin gene-related peptide type 1 receptor-like	0.065
col17a1a	collagen, type XVII, alpha 1a	0.065
col1a1a	collagen, type I, alpha 1a	0.065
clptm1	cleft lip and palate associated transmembrane protein 1	0.064
nkx2.3	NK2 transcription factor related 3	0.064
ptp4a3	protein tyrosine phosphatase type IVA, member 3	0.064
stm	starmaker	0.063
nf1b	neurofibromin 1b	0.063	Mouse
usp4	ubiquitin specific protease 4 (proto-oncogene)	0.063
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.063
trim13	tripartite motif-containing 13	0.063
lass2	LAG1 homolog, ceramide synthase 2 (S. cerevisiae)	0.063
il8	interleukin 8	0.063
ptrfb	polymerase I and transcript release factor b	0.063
tbx15	T-box 15	0.062
chrm2a	cholinergic receptor, muscarinic 2a	0.062
adora2b	adenosine A2b receptor	0.062
adipor1b	adiponectin receptor 1b	0.062
epor	erythropoietin receptor	0.062
esama	endothelial cell adhesion molecule a	0.062
otx5	orthodenticle homolog 5	0.062
kdr	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.062
dynlrb1	dynein, light chain, roadblock-type 1	0.062
caspa	caspase a	0.062
serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.062
hsp70l	heat shock cognate 70-kd protein, like	0.062
txnrd1	thioredoxin reductase 1	0.061
igfbp1a	insulin-like growth factor binding protein 1a	0.061
mapk15	mitogen-activated protein kinase 15	0.061
cct8	chaperonin containing TCP1, subunit 8 (theta)	0.061
oprd1b	opioid receptor, delta 1b	0.060
zmynd11	zinc finger, MYND domain containing 11	0.060	Human
mapkapk2a	mitogen-activated protein kinase-activated protein kinase 2a	0.060
tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.060
zgc:193613	zgc:193613	0.060
shroom4	shroom family member 4	0.060
usp10	ubiquitin specific peptidase 10	0.060
rtn4rl1	reticulon 4 receptor-like 1	0.060
dvl2	dishevelled, dsh homolog 2 (Drosophila)	0.060
sod1	superoxide dismutase 1, soluble	0.060
unc5c	unc-5 homolog C (C. elegans)	0.059
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.059
si:ch211-89f7.4	si:ch211-89f7.4	0.059
prkaa1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.059
fcho2	FCH domain only 2	0.059
smg7	Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)	0.059
apoc2	apolipoprotein C-II	0.059
nr0b1	nuclear receptor subfamily 0, group B, member 1	0.059
arpc1b	actin related protein 2/3 complex, subunit 1B	0.058
ubin	ataxin-1 ubiquitin-like interacting protein	0.058
top1l	topoisomerase (DNA) I, like	0.058
csnk1da	casein kinase 1, delta a	0.058
hoxd4a	homeo box D4a	0.058
fam3c	family with sequence similarity 3, member C	0.058
sulf2l	sulfatase 2, like	0.058
tp53bp2	tumor protein p53 binding protein, 2	0.058
socs1	suppressor of cytokine signaling 1	0.057
rp2	retinitis pigmentosa 2 (X-linked recessive)	0.057
ntn1b	netrin 1b	0.057
chmp1a	chromatin modifying protein 1A	0.057
LOC556849	ectonucleoside triphosphate diphosphohydrolase 5-like	0.057
lum	lumican	0.057
xrcc5	X-ray repair complementing defective repair in Chinese hamster cells 5	0.056
cx43.4	connexin 43.4	0.056
hbegfa	heparin-binding EGF-like growth factor a	0.056
inhbab	inhibin, beta Ab	0.056	Human
nr2f6a	nuclear receptor subfamily 2, group F, member 6a	0.056
mapk7	mitogen-activated protein kinase 7	0.056	Human
hsd17b3	hydroxysteroid (17-beta) dehydrogenase 3	0.056
itgb4	integrin, beta 4	0.056
ext1b	exostoses (multiple) 1b	0.056
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.056
irx2a	iroquois homeobox protein 2, a	0.055
traf4a	tnf receptor-associated factor 4a	0.055
mmp15b	matrix metallopeptidase 15b	0.055
nrxn2a	neurexin 2a	0.055
rab22a	RAB22A, member RAS oncogene family	0.055
tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.055
nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.055
erbb3a	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a	0.055
zgc:55347	zgc:55347	0.054
cyp17a1	cytochrome P450, family 17, subfamily A, polypeptide 1	0.054
mknk1	MAP kinase interacting serine/threonine kinase 1	0.054
itga7	integrin, alpha 7	0.054
snai2	snail homolog 2 (Drosophila)	0.054	Mouse
si:dkeyp-68f6.1	si:dkeyp-68f6.1	0.054
hmga1a	high mobility group AT-hook 1a	0.054
pvrl1a	poliovirus receptor-related 1a	0.054
b4galt5	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5	0.054
th	tyrosine hydroxylase	0.054
sox7	SRY-box containing gene 7	0.053
rras	related RAS viral (r-ras) oncogene homolog	0.053
zgc:56706	zgc:56706	0.053
kitb	kit receptor b	0.053
zgc:158327	zgc:158327	0.053
gyltl1b	glycosyltransferase-like 1b	0.053
taf3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto	0.053
avpl	arginine vasopressin-like	0.052
mapk1	mitogen-activated protein kinase 1	0.052
rhoaa	ras homolog gene family, member Aa	0.052
hmx4	H6 family homeobox 4	0.052
fkbp5	FK506 binding protein 5	0.052
plag1	pleiomorphic adenoma gene 1	0.052
cdh4	cadherin 4, retinal	0.052
cdh5	cadherin 5	0.052
psmd11b	proteasome (prosome, macropain) 216S subunit, non-ATPase, 11b	0.052
ldb1a	LIM-domain binding factor 1a	0.052
hsp47	heat shock protein 47	0.052
pdia4	protein disulfide isomerase associated 4	0.052
zgc:122977	zgc:122977	0.052
m17	IL-6 subfamily cytokine M17	0.052
wasb	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b	0.051
col4a4	collagen, type IV, alpha 4	0.051
hdr	hematopoietic death receptor	0.051
ntrk2a	neurotrophic tyrosine kinase, receptor, type 2a	0.051
rela	v-rel reticuloendotheliosis viral oncogene homolog A	0.051	Human Mouse
cnr1	cannabinoid receptor 1	0.051
rac2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.051
nfe2l3	nuclear factor (erythroid-derived 2)-like 3	0.051
ddr2b	discoidin domain receptor family, member 2b	0.051
etv1	ets variant gene 1	0.051
cx32.3	connexin 32.3	0.051
klfd	Kruppel-like factor d	0.051
phex	phosphate regulating gene with homologues to endopeptidases on the X chromosome	0.051
u2af2b	U2 small nuclear RNA auxiliary factor 2b	0.051
rfng	radical fringe homolog (Drosophila)	0.051
hdac4	histone deacetylase 4	0.050
wu:fe23c11	wu:fe23c11	0.050
akt2	v-akt murine thymoma viral oncogene homolog 2	0.050
sptlc1	serine palmitoyltransferase, long chain base subunit 1	0.050
ptprsa	protein tyrosine phosphatase, receptor type, s, a	0.050
mcoln1	mucolipin 1	0.050
cyp11a1	cytochrome P450, subfamily XIA, polypeptide 1	0.050
gfra1a	gdnf family receptor alpha 1a	0.050
grem2	gremlin 2, cysteine knot superfamily	0.050
zgc:56049	zgc:56049	0.050
ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.050
crip2	cysteine-rich protein 2	0.050
dnajb6b	DnaJ (Hsp40) homolog, subfamily B, member 6b	0.050
midn	midnolin	0.050
arfip1	ADP-ribosylation factor interacting protein 1 (arfaptin 1)	0.050
gnaia	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a	0.050
ptmab	prothymosin, alpha b	0.049
hmbsb	hydroxymethylbilane synthase, b	0.049
bbc3	BCL2 binding component 3	0.049
hspb8	heat shock protein, alpha-crystallin-related, b8	0.049
lsm12	LSM12 homolog (S. cerevisiae)	0.049
ldhbb	lactate dehydrogenase Bb	0.049
gng5	guanine nucleotide binding protein (G protein), gamma 5	0.048
asph	aspartate beta-hydroxylase	0.048
khdrbs1a	KH domain containing, RNA binding, signal transduction associated 1a	0.048
tgfb3	transforming growth factor, beta 3	0.048
adra2b	adrenergic, alpha-2B-, receptor	0.048
flii	flightless I homolog (Drosophila)	0.048
cdk8	cyclin-dependent kinase 8	0.048
adh8b	alcohol dehydrogenase 8b	0.048
eif4g2a	eukaryotic translation initiation factor 4, gamma 2a	0.048
map2k2a	mitogen-activated protein kinase kinase 2a	0.048
tnfsf10l2	tumor necrosis factor (ligand) superfamily, member 10 like 2	0.048	Human Zebrafish
wnk1	WNK lysine deficient protein kinase 1	0.048
myh11a	myosin, heavy polypeptide 11, smooth muscle a	0.048
scinlb	scinderin like b	0.048
sp2	sp2 transcription factor	0.048
smc1al	structural maintenance of chromosomes 1A, like	0.047
si:ch211-57g18.1	si:ch211-57g18.1	0.047
cdh23	cadherin-like 23	0.047
lifra	leukemia inhibitory factor receptor alpha	0.047
atp13a2	ATPase type 13A2	0.047
pitpnb	phosphotidylinositol transfer protein, beta	0.047
hspa5	heat shock protein 5	0.047
bcl7ba	B-cell CLL/lymphoma 7B, a	0.047
stat5.2	signal transducer and activator of transcription 5.2	0.047
gch1	GTP cyclohydrolase 1	0.047
gli3	GLI-Kruppel family member GLI3	0.047
prpsap2	phosphoribosyl pyrophosphate synthetase-associated protein 2	0.047
tssc1	tumor suppressing subtransferable candidate 1	0.047
atm	ataxia telangiectasia mutated	0.047
mrc1a	mannose receptor, C type 1a	0.046
pomca	proopiomelanocortin a	0.046
LOC100004946	transient receptor potential cation channel subfamily M member 4-like	0.046
anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.046
iqgap1	IQ motif containing GTPase activating protein 1	0.046
LOC555739	serine/threonine-protein kinase LMTK1-like	0.046
rorca	RAR-related orphan receptor C a	0.046
kif5bb	kinesin family member 5B, b	0.046
ranbp1	RAN binding protein 1	0.046
cul2	cullin 2	0.046
anxa2b	annexin A2b	0.046
bcl2	B-cell leukemia/lymphoma 2	0.046	Human
slc15a2	solute carrier family 15 (H+/peptide transporter), member 2	0.046
cldn2	claudin 2	0.046
ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.046
waca	WW domain containing adaptor with coiled-coil a	0.046
LOC792676	similar to N-myc-interactor (Nmi) (N-myc and STAT interactor)	0.046
tagln	transgelin	0.045
myb	myeloblastosis oncogene	0.045
si:rp71-1p14.10	si:rp71-1p14.10	0.045
zgc:77155	zgc:77155	0.045
synpo2la	synaptopodin 2-like a	0.045
prl	prolactin	0.045
emx2	empty spiracles homeobox 2	0.045
zgc:113312	zgc:113312	0.045
wnt4a	wingless-type MMTV integration site family, member 4a	0.045
cldni	claudin i	0.045
gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.045
prox1	prospero-related homeobox gene 1	0.045
ntn4	netrin 4	0.045
abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.045
cry3	cryptochrome 3	0.044
ahr2	aryl hydrocarbon receptor 2	0.044
foxc1b	forkhead box C1b	0.044
cfhl4	complement factor H like 4	0.044
agtr2	angiotensin II receptor, type 2	0.044	Human
mcamb	melanoma cell adhesion molecule b	0.044
npm4	nucleophosmin/nucleoplasmin, 4	0.044
fras1	Fraser syndrome 1	0.044
rhcgb	Rhesus blood group, C glycoprotein b	0.044
prkcz	protein kinase C, zeta	0.044
apaf1	apoptotic protease activating factor 1	0.044
LOC567405	novel protein similar to vertebrate megakaryocyte-associated tyrosine kinase (MATK)	0.044
scinla	scinderin like a	0.044
rtn4r	reticulon 4 receptor	0.044
ltk	leukocyte tyrosine kinase	0.043
spna2	spectrin alpha 2	0.043
fshb	follicle stimulating hormone, beta polypeptide	0.043
plagl2	pleiomorphic adenoma gene-like 2	0.043
col5a2l	collagen, type V, alpha 2-like	0.043
zgc:172246	zgc:172246	0.043
tfr1a	transferrin receptor 1a	0.043
elovl5	ELOVL family member 5, elongation of long chain fatty acids (yeast)	0.043
hoxc13b	homeo box C13b	0.043
zgc:136346	zgc:136346	0.043
pdlim1	PDZ and LIM domain 1 (elfin)	0.043
ube2g2	ubiquitin-conjugating enzyme E2G 2	0.043
she	Src homology 2 domain containing E	0.042
gata6	GATA-binding protein 6	0.042
shmt2	serine hydroxymethyltransferase 2 (mitochondrial)	0.042
tm9sf2	transmembrane 9 superfamily member 2	0.042
tgfbi	transforming growth factor, beta-induced	0.042
angpt1	angiopoietin 1	0.042
gnrh3	gonadotropin-releasing hormone 3	0.042
fas	Fas (TNF receptor superfamily, member 6)	0.042	Mouse
grn1	granulin 1	0.042
morf4l1	mortality factor 4 like 1	0.042
rab11a	RAB11a, member RAS oncogene family	0.042
crb3b	crumbs homolog 3b	0.042
sat1a	spermidine/spermine N1-acetyltransferase 1a	0.042
hic1	hypermethylated in cancer 1	0.042
rpa1	replication protein A1	0.041
gng2	guanine nucleotide binding protein (G protein), gamma 2	0.041
arfgap2	ADP-ribosylation factor GTPase activating protein 2	0.041
prpf3	PRP3 pre-mRNA processing factor 3 homolog (yeast)	0.041
emx3	empty spiracles homeobox 3	0.041
tram1	translocating chain-associating membrane protein 1	0.041
per3	period homolog 3 (Drosophila)	0.041
dnajb12	DnaJ (Hsp40) homolog, subfamily B, member 12	0.041
grifin	galectin related inter-fiber protein	0.041
agr2	anterior gradient homolog 2 (Xenopus laevis)	0.041
fgf13b	fibroblast growth factor 13b	0.041
col17a1b	collagen, type XVII, alpha 1b	0.041
bmp7b	bone morphogenetic protein 7b	0.041
eif4a1a	eukaryotic translation initiation factor 4A, isoform 1A	0.041
cish	cytokine inducible SH2-containing protein	0.041
comta	catechol-O-methyltransferase a	0.041
wars	tryptophanyl-tRNA synthetase	0.040
bbs2	Bardet-Biedl syndrome 2	0.040
sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.040
llgl2	lethal giant larvae homolog 2 (Drosophila)	0.040
il11ra	interleukin 11 receptor, alpha	0.040
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.040
per2	period homolog 2 (Drosophila)	0.040
cntfr	ciliary neurotrophic factor receptor	0.040
grk7a	G-protein-coupled receptor kinase 7a	0.040
crabp2b	cellular retinoic acid binding protein 2, b	0.040
f5	coagulation factor V	0.040
gh1	growth hormone 1	0.039
mllt10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	0.039
prrx1a	paired related homeobox 1a	0.039
mbnl3	muscleblind-like 3 (Drosophila)	0.039
epas1b	endothelial PAS domain protein 1b	0.039
smap1	stromal membrane-associated protein 1	0.039
hbae3	hemoglobin alpha embryonic-3	0.039
pea3	ETS-domain transcription factor pea3	0.039
aph1b	anterior pharynx defective 1B	0.039
gcm2	glial cells missing homolog 2 (Drosophila)	0.039
ythdf1	YTH domain family, member 1	0.039
syncripl	synaptotagmin binding, cytoplasmic RNA interacting protein, like	0.039
LOC100000500	sclerostin-like	0.039
zgc:153060	zgc:153060	0.039
sod2	superoxide dismutase 2, mitochondrial	0.039
derl1	Der1-like domain family, member 1	0.039
casp8	caspase 8, apoptosis-related cysteine peptidase	0.039	Human Mouse
nrp1b	neuropilin 1b	0.039	Mouse
slc15a1b	solute carrier family 15 (oligopeptide transporter), member 1b	0.039
chst11	carbohydrate (chondroitin 4) sulfotransferase 11	0.039
vps35	vacuolar protein sorting 35 (yeast)	0.039
bad	BCL2-antagonist of cell death	0.039
LOC100000934	hypothetical protein LOC100000934	0.039
bmp3	bone morphogenetic protein 3	0.039
card14	caspase recruitment domain family, member 14	0.039
wu:fi25h02	wu:fi25h02	0.039
zgc:162630	zgc:162630	0.038
ndel1a	nudE nuclear distribution gene E homolog like 1 (A. nidulans) A	0.038
atp6v1al	ATPase, H+ transporting, lysosomal V1 subunit A, like	0.038
olig1	oligodendrocyte lineage transcription factor 1	0.038
slc4a1a	solute carrier family 4, anion exchanger, member 1a	0.038
rag2	recombination activating gene 2	0.038
zgc:56062	zgc:56062	0.038
atp1a1a.2	ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide	0.038
dlx5a	distal-less homeobox gene 5a	0.038
zeb2b	zinc finger E-box binding homeobox 2b	0.038
ryr1a	ryanodine receptor 1a (skeletal)	0.038
zgc:153286	zgc:153286	0.038
rhoub	ras homolog gene family, member Ub	0.038
ier5l	immediate early response 5-like	0.038
tgif1	TGFB-induced factor homeobox 1	0.038
brf1a	BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIBa	0.038
stxbp2	syntaxin binding protein 2	0.038
dpysl4	dihydropyrimidinase-like 4	0.038
il13ra2	interleukin 13 receptor, alpha 2	0.038
nucks1a	nuclear casein kinase and cyclin-dependent kinase substrate 1a	0.038
tgm2b	transglutaminase 2b	0.038
tcf12	transcription factor 12	0.037
tyrp1b	tyrosinase-related protein 1b	0.037
bzw1b	basic leucine zipper and W2 domains 1b	0.037
trpc6	transient receptor potential cation channel, subfamily C, member 6	0.037
caspb	caspase b and caspase b-like	0.037
csrp1a	cysteine and glycine-rich protein 1a	0.037
tfec	transcription factor EC	0.037
fzd6	frizzled homolog 6 (Drosophila)	0.037
pcdh19	protocadherin 19	0.037
polb	polymerase (DNA directed), beta	0.037
smoc2	secreted modular calcium binding protein 2	0.037
p2rx3b	purinergic receptor P2X, ligand-gated ion channel, 3b	0.037
mef2a	myocyte enhancer factor 2a	0.037
hpx	hemopexin	0.037
polr3e	polymerase (RNA) III (DNA directed) polypeptide E	0.037
kng1	kininogen 1	0.037
ighz	immunoglobulin heavy constant zeta	0.037
trpa1a	transient receptor potential cation channel, subfamily A, member 1a	0.037
zgc:55558	zgc:55558	0.037
ppp1cab	protein phosphatase 1, catalytic subunit, alpha isoform b	0.037	Mouse
ywhabb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b	0.037
dnajb11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.037
pafah1b1b	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b	0.037
f2	coagulation factor II (thrombin)	0.036
fbxl14b	F-box and leucine-rich repeat protein 14b	0.036
slc6a5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	0.036
tg	thyroglobulin	0.036
pgp	phosphoglycolate phosphatase	0.036
kirrela	kin of IRRE like a	0.036
sdc2	syndecan 2	0.036
cyyr1	cysteine and tyrosine-rich protein 1	0.036
copeb	core promoter element binding protein	0.036
bactin1	bactin1	0.036
bzw1a	basic leucine zipper and W2 domains 1a	0.036
loxl2b	lysyl oxidase-like 2b	0.036
csf1ra	colony stimulating factor 1 receptor, a	0.036
zgc:55886	zgc:55886	0.036
nr4a2b	nuclear receptor subfamily 4, group A, member 2b	0.036
pofut2	protein O-fucosyltransferase 2	0.036
cd82b	CD82 antigen, b	0.036
acp5b	acid phosphatase 5b, tartrate resistant	0.036
pafah1b1a	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a	0.036
fam53b	family with sequence similarity 53, member B	0.036
lzts2a	leucine zipper, putative tumor suppressor 2a	0.036
twf1a	twinfilin, actin-binding protein, homolog 1a	0.036
rhag	Rhesus blood group-associated glycoprotein	0.036
lmna	lamin A	0.035	Mouse
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.035
antxr2a	anthrax toxin receptor 2a	0.035
ccbe1	collagen and calcium binding EGF domains 1	0.035
pah	phenylalanine hydroxylase	0.035
stk17b	serine/threonine kinase 17b (apoptosis-inducing)	0.035
casp9	caspase 9, apoptosis-related cysteine protease	0.035
serpind1	serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1	0.035
tectb	tectorin beta	0.035
COX1	cytochrome c oxidase subunit I	0.035
copb2	coatomer protein complex, subunit beta 2	0.035
ngfrl	nerve growth factor receptor (TNFR superfamily, member 16) like	0.035
pknox1.1	pbx/knotted 1 homeobox 1.1	0.035
cldn15a	claudin 15a	0.035
ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.035
ck2b	casein kinase 2 beta	0.035
fgf20b	fibroblast growth factor 20b	0.035
bbs4	Bardet-Biedl syndrome 4	0.035
fzd5	frizzled homolog 5	0.035
lasp1	LIM and SH3 protein 1	0.035
ntn1a	netrin 1a	0.035	Zebrafish
creb3l3l	cAMP responsive element binding protein 3-like 3 like	0.035
adipor1a	adiponectin receptor 1a	0.035
ifrd1	interferon-related developmental regulator 1	0.035
arpc2	actin related protein 2/3 complex, subunit 2	0.035
zgc:66427	zgc:66427	0.035
psma6b	proteasome (prosome, macropain) subunit, alpha type, 6b	0.035
wu:fc27e05	wu:fc27e05	0.034
bmp15	bone morphogenetic protein 15	0.034
crestin	crestin	0.034
itga6b	integrin, alpha 6b	0.034
arf6	ADP-ribosylation factor 6	0.034
arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.034
dusp1	dual specificity phosphatase 1	0.034
LOC100002342	carboxypeptidase A6-like	0.034
slc35c1	solute carrier family 35, member C1	0.034
itga2b	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)	0.034
abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.034
numbl	numb homolog (Drosophila)-like	0.034
ptger4b	prostaglandin E receptor 4 (subtype EP4) b	0.034
atf4b1	activating transcription factor 4b1 (tax-responsive enhancer element B67)	0.034
timp2a	tissue inhibitor of metalloproteinase 2a	0.034
uck2a	uridine-cytidine kinase 2a	0.034
msi1	musashi homolog 1 (Drosophila)	0.034
vtg1	vitellogenin 1	0.034
pdip5	protein disulfide isomerase-related protein (provisional)	0.034
igf2a	insulin-like growth factor 2a	0.034
cdc42se1	CDC42 small effector 1	0.034
ren	renin	0.034
rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.034
timp2b	tissue inhibitor of metalloproteinase 2b	0.034
tbc1d23	TBC1 domain family, member 23	0.033
fgf4	fibroblast growth factor 4	0.033
tmem41aa	transmembrane protein 41aa	0.033
tmem115	transmembrane protein 115	0.033
kctd10	potassium channel tetramerisation domain containing 10	0.033
calr	calreticulin and calreticulin	0.033
zgc:172101	zgc:172101	0.033
il6st	interleukin 6 signal transducer	0.033
epha2	eph receptor A2	0.033
mknk2b	MAP kinase-interacting serine/threonine kinase 2b	0.033
bmpr2a	bone morphogenetic protein receptor, type II a (serine/threonine kinase)	0.033
hspa4a	heat shock protein 4a	0.033
smad3a	MAD homolog 3a (Drosophila)	0.033
cpt2	carnitine palmitoyltransferase II	0.033
sult1st3	sulfotransferase family 1, cytosolic sulfotransferase 3	0.033
agt	angiotensinogen	0.033	Human
kdelr2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	0.033
si:dkey-42i9.4	si:dkey-42i9.4	0.033
phox2a	paired-like homeobox 2a	0.033
syk	spleen tyrosine kinase	0.033
pdgfrl	platelet-derived growth factor receptor-like	0.033
hnrnpab	heterogeneous nuclear ribonucleoprotein A/B	0.033
capn1a	calpain 1, (mu/I) large subunit a	0.033
flot2a	flotillin 2a	0.033
card9	caspase recruitment domain family, member 9	0.033
gbp1	guanylate binding protein 1	0.033
paqr8	progestin and adipoQ receptor family member VIII	0.033
hsp70	heat shock cognate 70-kd protein	0.033
birc5a	baculoviral IAP repeat-containing 5a	0.033
pi4k2a	phosphatidylinositol 4-kinase type 2 alpha	0.033
actr1	ARP1 actin-related protein 1, centractin (yeast)	0.032
st8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	0.032
smad2	MAD homolog 2 (Drosophila)	0.032
tardbpl	TAR DNA binding protein, like	0.032
flot1	flotillin 1	0.032
pgam5	phosphoglycerate mutase family member 5	0.032
pitpna	phosphatidylinositol transfer protein, alpha	0.032
klhl18	kelch-like 18 (Drosophila)	0.032
rtcd1	RNA terminal phosphate cyclase domain 1	0.032
tpm4	tropomyosin 4	0.032
angptl2	angiopoietin-like 2	0.032
fam76b	family with sequence similarity 76, member B	0.032
lepr	leptin receptor	0.032
ezh2	enhancer of zeste homolog 2 (Drosophila)	0.032
calrl	calreticulin like	0.032
zgc:113200	zgc:113200	0.032
vat1	vesicle amine transport protein 1 homolog (T californica)	0.032
riok3	RIO kinase 3 (yeast)	0.032
apg3l	APG3 autophagy 3-like	0.032
gcga	glucagon a and glucagon a-like	0.032
tcf4	transcription factor 4	0.032
pmp22a	peripheral myelin protein 22a	0.032
adcyap1r1	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	0.032