IMP: Integrative Multi-species Prediction

Danio rerio

20 genes annotated in zebrafish

purine ribonucleotide biosynthetic process

The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in zebrafishInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "purine ribonucleotide biosynthetic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "purine ribonucleotide biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
mc4r	melanocortin 4 receptor	0.953
uts1	urotensin 1	0.893
LOC100003330	melanocortin-2 receptor accessory protein 2-like	0.877
mc2r	melanocortin 2 receptor	0.810
avpl	arginine vasopressin-like	0.592	Mouse
drd2b	dopamine receptor D2b	0.504	Human Rat
LOC569642	hypothetical protein LOC569642	0.487
nf1a	neurofibromin 1a	0.460	Mouse Fly
adrb1	adrenergic receptor, beta 1	0.427	Human Zebrafish Rat
mchr1b	melanin-concentrating hormone receptor 1b	0.403
adrb2a	adrenergic receptor, beta 2a	0.366
LOC555482	tachykinin receptor 3-like	0.362
eef2l2	eukaryotic translation elongation factor 2, like 2	0.358
gc2	guanylyl cyclase 2	0.357	Zebrafish Rat
vipr2	vasoactive intestinal peptide receptor 2	0.352	Zebrafish
LOC559201	similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3)	0.347
rtn1a	reticulon 1a	0.327
adcyap1r1a	adenylate cyclase activating polypeptide 1 receptor 1a	0.326
gucy2f	guanylate cyclase 2F, retinal	0.321
calcrla	calcitonin receptor-like a	0.306	Zebrafish
cyp11b2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.302
cnn2	calponin 2	0.292
drd3	dopamine receptor D3	0.272	Human Rat
adra2b	adrenergic, alpha-2B-, receptor	0.262
cx55.5	connexin 55.5	0.230
adra2c	adrenergic, alpha-2C-, receptor	0.162
drd2a	dopamine receptor D2a	0.154	Human Rat
si:ch211-209p5.2	si:ch211-209p5.2	0.153
gnrh2	gonadotropin-releasing hormone 2	0.150
zgc:77123	zgc:77123	0.136
si:dkey-228g21.4	si:dkey-228g21.4	0.128
nf1b	neurofibromin 1b	0.128	Mouse Fly
gria2b	glutamate receptor, ionotropic, AMPA 2b	0.126
tert	telomerase reverse transcriptase	0.123
mc1r	melanocortin 1 receptor	0.120	Zebrafish
kiss1rb	KISS1 receptor b	0.118
rag1	recombination activating gene 1	0.117
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.115
opn4l	opsin 4, like	0.113
dbh	dopamine beta hydroxylase	0.109
guca1c	guanylate cyclase activator 1C	0.106
hcrtr2	hypocretin (orexin) receptor 2	0.096
slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.094
oprd1a	opioid receptor, delta 1a	0.090
twist1b	twist1b	0.087
saga	S-antigen; retina and pineal gland (arrestin) a	0.083
oxtl	oxytocin-like	0.083	Mouse
gadd45g	growth arrest and DNA-damage-inducible, gamma	0.082
spon1a	spondin 1a	0.078
arfip2b	ADP-ribosylation factor interacting protein 2b	0.077
th2	tyrosine hydroxylase 2	0.075
ndufa4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4	0.073
fes	feline sarcoma oncogene	0.073
nt5e	5'-nucleotidase, ecto (CD73)	0.071
htr1aa	5-hydroxytryptamine (serotonin) receptor 1A a	0.071
bsk146	brain specific kinase 146	0.070
cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	0.070
gch2	GTP cyclohydrolase 2	0.068
mchr1a	melanin-concentrating hormone receptor 1a	0.068
sst3	somatostatin 3	0.067
kif5ba	kinesin family member 5B, a	0.067
crhbp	corticotropin releasing hormone binding protein	0.066
c1qtnf4	C1q and tumor necrosis factor related protein 4	0.066
nlgn4a	neuroligin 4a	0.066
foxl1	forkhead box L1	0.062
fermt2	fermitin family homolog 2 (Drosophila)	0.059
opn1lw1	opsin 1 (cone pigments), long-wave-sensitive, 1	0.059
mstnb	myostatin b	0.058
pvalb2	parvalbumin 2	0.057
sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.056
tagln2	transgelin 2	0.056
si:ch211-14k19.8	si:ch211-14k19.8	0.056
hoxc12b	homeo box C12b	0.054
furinb	furin (paired basic amino acid cleaving enzyme) b	0.054
vdac2	voltage-dependent anion channel 2	0.053
jun	jun proto-oncogene	0.053
valopa	vertebrate ancient long opsin a	0.052
rx1	retinal homeobox gene 1	0.050
zgc:91860	zgc:91860	0.050
sox5	SRY-box containing gene 5	0.050
chrm2a	cholinergic receptor, muscarinic 2a	0.049
pnrc2	proline-rich nuclear receptor coactivator 2	0.049
ros1	v-ros UR2 sarcoma virus oncogene homolog 1 (avian)	0.049
sgk1	serum/glucocorticoid regulated kinase 1	0.048
pth2	parathyroid hormone 2	0.048
wu:fc24e06	wu:fc24e06	0.047
nrl	neural retina leucine zipper	0.046
pyya	peptide YYa	0.046
LOC555504	novel protocadherin protein	0.045
fshr	follicle stimulating hormone receptor	0.045
adra2a	adrenergic, alpha-2A-, receptor	0.045
gpr182	G protein-coupled receptor 182	0.044
drd2l	dopamine receptor D2 like	0.043
vegfab	vascular endothelial growth factor Ab	0.043
mtnr1ba	melatonin receptor type 1B a	0.043
gsdf	gonadal somatic cell derived factor	0.043
atp6v0cb	ATPase, H+ transporting, lysosomal, V0 subunit c, b	0.043
eno1	enolase 1, (alpha)	0.042
nlgn2b	neuroligin 2b	0.042
grk7a	G-protein-coupled receptor kinase 7a	0.042
gap43	growth associated protein 43	0.041
alx4a	aristaless-like homeobox 4a	0.041
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.041
slc8a4b	solute carrier family 8 (sodium/calcium exchanger), member 4b	0.040
penka	proenkephalin a	0.039
sc:d812	sc:d812	0.039
rbp4l	retinol binding protein 4, like	0.039
nlgn1	neuroligin 1	0.038
ecm2	extracellular matrix protein 2, female organ and adipocyte specific	0.038
cbsa	cystathionine-beta-synthase a	0.038
LOC563363	cholesterol side-chain cleavage enzyme, mitochondrial-like	0.038
gfra1b	gdnf family receptor alpha 1b	0.037
bmp8a	bone morphogenetic protein 8a	0.036
kif5c	kinesin family member 5C	0.036
kal1a	Kallmann syndrome 1a sequence	0.035
uts2a	urotensin 2, alpha	0.035
chrnb3b	cholinergic receptor, nicotinic, beta polypeptide 3b	0.034
pcdh17	protocadherin 17	0.034
klf7l	Kruppel-like factor 7 (ubiquitous), like	0.034
opn1mw1	opsin 1 (cone pigments), medium-wave-sensitive, 1	0.033
si:ch211-67f24.7	si:ch211-67f24.7	0.032
adipoql	adiponectin, C1Q and collagen domain containing, like	0.032
crygs2	crystallin, gamma S2	0.032
alk	anaplastic lymphoma kinase (Ki-1)	0.032
zgc:110179	zgc:110179	0.032
ckmb	creatine kinase, muscle b	0.032
gdnf	glial cell derived neurotrophic factor	0.032
cyp51	cytochrome P450, family 51	0.032
calcr	calcitonin receptor	0.032
gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.031
uchl1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.031
esr1	estrogen receptor 1	0.030
cx52.6	connexin 52.6	0.030
sagb	S-antigen; retina and pineal gland (arrestin) b	0.030
clock	clock	0.029
bhlha15	basic helix-loop-helix family, member a15	0.029
otpa	orthopedia homolog a	0.029
valopb	vertebrate ancient long opsin b	0.029
tgfbi	transforming growth factor, beta-induced	0.029
arf5	ADP-ribosylation factor 5	0.029
thrb	thyroid hormone receptor beta	0.028
htr1ab	5-hydroxytryptamine (serotonin) receptor 1A b	0.028	Zebrafish
pgam2	phosphoglycerate mutase 2 (muscle)	0.028
guca1d	guanylate cyclase activator 1d	0.028
mych	myelocytomatosis oncogene homolog	0.027
frem2a	Fras1 related extracellular matrix protein 2a	0.027
ywhai	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide	0.027
prdm15	PR domain containing 15	0.027
lifrb	leukemia inhibitory factor receptor alpha b	0.027
npy8br	neuropeptide Y receptor Y8b	0.027
alx4b	aristaless-like homeobox 4b	0.027
ucn3l	urocortin 3, like	0.026
crygm4	crystallin, gamma M4	0.026
npb	neuropeptide B	0.026
trpc1	transient receptor potential cation channel, subfamily C, member 1	0.026
flj13639	flj13639	0.026
neurod2	neurogenic differentiation 2	0.026
rs1	retinoschisis (X-linked, juvenile) 1	0.026
adra2db	adrenergic, alpha-2D-, receptor b	0.025
ar	androgen receptor	0.025
hoxa11a	homeo box A11a	0.025
zgc:64098	zgc:64098	0.025
figf	c-fos induced growth factor	0.025
zgc:162213	zgc:162213	0.025
il22	interleukin 22	0.025
dusp5	dual specificity phosphatase 5	0.025
igfbp5a	insulin-like growth factor binding protein 5a	0.025
tkt	transketolase	0.025
onecut1	one cut domain, family member 1	0.024
esrrga	estrogen-related receptor gamma a	0.024
zgc:55813	zgc:55813	0.024
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.024
si:rp71-40n14.1	si:rp71-40n14.1	0.024
gc3	guanylyl cyclase 3	0.023	Zebrafish Rat
zgc:153990	zgc:153990	0.023
aldoaa	aldolase a, fructose-bisphosphate, a	0.023	Human
ahi1	Abelson helper integration site 1	0.023
pp	pyrophosphatase (inorganic)	0.023
or115-10	odorant receptor, family F, subfamily 115, member 10	0.023
ptpra	protein tyrosine phosphatase, receptor type, A	0.022
ltk	leukocyte tyrosine kinase	0.022
cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.022
ntrk3b	neurotrophic tyrosine kinase, receptor, type 3b	0.022
pdlim1	PDZ and LIM domain 1 (elfin)	0.022
LOC569128	hypothetical protein LOC569128	0.022
fam3c	family with sequence similarity 3, member C	0.022
calm1a	calmodulin 1a	0.021
cldnk	claudin k	0.021
si:dkey-24h22.4	si:dkey-24h22.4	0.021
stx1b	syntaxin 1B	0.021
cd63	Cd63 antigen	0.020
hdlbp	high density lipoprotein-binding protein (vigilin)	0.020
drd4a	dopamine receptor D4a	0.020	Human
pax3b	paired box gene 3b	0.020
socs1	suppressor of cytokine signaling 1	0.020
gnat2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.020
mllt11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	0.020
dio2	deiodinase, iodothyronine, type II	0.020
syngr1a	synaptogyrin 1a	0.020
LOC799274	kinesin heavy chain isoform 5A-like	0.020
si:ch211-139a5.1	si:ch211-139a5.1	0.020
si:ch211-163l21.8	si:ch211-163l21.8	0.019
zgc:63633	zgc:63633	0.019
gapdhs	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.019
cfl2l	cofilin 2, like	0.019
zgc:103671	zgc:103671	0.019
tfe3a	transcription factor binding to IGHM enhancer 3a	0.019
mpp5b	membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5b)	0.019
slc6a8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.019
zgc:56548	zgc:56548	0.019
inhbab	inhibin, beta Ab	0.019
prkcea	protein kinase C, epsilon a	0.019
arfip2a	ADP-ribosylation factor interacting protein 2a	0.019
LOC799612	prolactin 2	0.019
ehd1	EH-domain containing 1	0.018
neurog3	neurogenin 3	0.018
slc6a17	solute carrier family 6, member 17	0.018
stx3a	syntaxin 3A	0.018
syt11a	synaptotagmin XIa	0.017
zgc:77060	zgc:77060	0.017
dclk2	doublecortin-like kinase 2	0.017
zgc:91926	zgc:91926	0.017
htr1bd	5-hydroxytryptamine (serotonin) receptor 1bd	0.017	Zebrafish
camk2g1	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1	0.017
cyb5r4	cytochrome b5 reductase 4	0.017
cnr1	cannabinoid receptor 1	0.017
zgc:85746	zgc:85746	0.017
nr1d2a	nuclear receptor subfamily 1, group D, member 2a	0.017
rxrab	retinoid x receptor, alpha b	0.017
pax7b	paired box gene 7b	0.017
inhbaa	inhibin, beta Aa	0.016
socs3a	suppressor of cytokine signaling 3a	0.016
vtg1	vitellogenin 1	0.016
cnr2	cannabinoid receptor 2	0.016
atp1b1a	ATPase, Na+/K+ transporting, beta 1a polypeptide	0.016
wu:fb17b11	wu:fb17b11	0.016
gpd2	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	0.016
nlgn2a	neuroligin 2a	0.016
cadm2a	cell adhesion molecule 2a	0.016
kif5bb	kinesin family member 5B, b	0.016
idh2	isocitrate dehydrogenase 2 (NADP+), mitochondrial	0.016
mao	monoamine oxidase	0.016
rpe65b	retinal pigment epithelium-specific protein 65b	0.016
appb	amyloid beta (A4) precursor protein b	0.016
adora2b	adenosine A2b receptor	0.016	Mouse Rat
atp2a1l	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 like	0.016
hpca	hippocalcin	0.015
got2b	glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2)	0.015
rho	rhodopsin	0.015
cyp1d1	cytochrome P450, family 1, subfamily D, polypeptide 1	0.015
slc1a2a	solute carrier family 1 (glial high affinity glutamate transporter), member 2a	0.015
aanat2	arylalkylamine N-acetyltransferase	0.015
hk1	hexokinase 1	0.015
zbtb4	zinc finger and BTB domain containing 4	0.015
npy4r	neuropeptide Y receptor Y4	0.015
paqr8	progestin and adipoQ receptor family member VIII	0.015
upk1a	uroplakin 1a	0.015
zgc:103530	zgc:103530	0.015
zgc:101581	zgc:101581	0.014
lhb	luteinizing hormone, beta polypeptide	0.014
adcyap1a	adenylate cyclase activating polypeptide 1a	0.014	Human Mouse
msi2a	musashi homolog 2a (Drosophila)	0.014
ryr2a	ryanodine receptor 2a (cardiac)	0.014
vip	vasoactive intestinal peptide	0.014
cyp1b1	cytochrome P450, family 1, subfamily B, polypeptide 1	0.014
zgc:110796	zgc:110796	0.014
igfbp6a	insulin-like growth factor binding protein 6a	0.014
ell2	elongation factor, RNA polymerase II, 2	0.014
mmp17b	matrix metallopeptidase 17b	0.014
lmo4b	LIM domain only 4b	0.014
fabp3	fatty acid binding protein 3, muscle and heart	0.014
atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	0.014
calm2a	calmodulin 2a (phosphorylase kinase, delta)	0.014
nlgn3b	neuroligin 3b	0.014
cdc42	cell division cycle 42	0.013
jazf1b	JAZF zinc finger 1b	0.013
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.013
mtnr1bb	melatonin receptor 1B b and melatonin receptor 1B	0.013
paqr7b	progestin and adipoQ receptor family member VII, b	0.013
hmgb1a	high-mobility group box 1a	0.013
zgc:56272	zgc:56272	0.013
cx27.5	connexin 27.5	0.013
plrg1	pleiotropic regulator 1	0.013
adcy5	adenylate cyclase 5	0.013
arl4ca	ADP-ribosylation factor-like 4Ca	0.013
ttc39c	tetratricopeptide repeat domain 39C	0.013
LOC100006249	carbohydrate sulfotransferase 2-like	0.013
esrrb	estrogen-related receptor beta	0.013
rab2a	RAB2A, member RAS oncogene family	0.013
clstn1	calsyntenin 1	0.013
hccs	holocytochrome c synthase	0.013
pvalb3	parvalbumin 3	0.013
oaz2b	ornithine decarboxylase antizyme 2b	0.013
hdc	histidine decarboxylase	0.013
sst1.1	somatostatin 1, tandem duplicate 1	0.013
grb2	growth factor receptor-bound protein 2	0.013
LOC794630	retinol-binding protein 3-like	0.013
mcamb	melanoma cell adhesion molecule b	0.012
vdac3	voltage-dependent anion channel 3	0.012
mapk1	mitogen-activated protein kinase 1	0.012
cfdl	complement factor D (adipsin) like	0.012
spry2	sprouty homolog 2	0.012
rtn4r	reticulon 4 receptor	0.012
opn1mw4	opsin 1 (cone pigments), medium-wave-sensitive, 4	0.012
fgfbp2	fibroblast growth factor binding protein 2	0.012
prdx2	peroxiredoxin 2	0.012
zgc:152873	zgc:152873	0.012
gnat1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	0.012
vps26a	vacuolar protein sorting 26 homolog A (yeast)	0.012
pgk1	phosphoglycerate kinase 1	0.012
or115-15	odorant receptor, family F, subfamily 115, member 15	0.012
plagl2	pleiomorphic adenoma gene-like 2	0.012
rhogc	ras homolog gene family, member Gc	0.012
clec14a	C-type lectin domain family 14, member A	0.012
hyou1	hypoxia up-regulated 1	0.012
LOC790901	glucose-dependent insulinotropic polypeptide	0.012
LOC100149148	novel protein similar to myosin heavy chain 4 (myhc4)	0.012
tie1	endothelium-specific receptor tyrosine kinase 1	0.012
drd1	dopamine receptor D1	0.011	Rat Fly
klf4	Kruppel-like factor 4	0.011
si:dkey-37m8.9	si:dkey-37m8.9	0.011
cry1a	cryptochrome 1a	0.011
agtr2	angiotensin II receptor, type 2	0.011
nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.011
hsd17b1	hydroxysteroid (17-beta) dehydrogenase 1	0.011
ca8	carbonic anhydrase VIII	0.011
ca4a	carbonic anhydrase IV a	0.011
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.011
mc5rb	melanocortin 5b receptor	0.011	Human
ptp4a1	protein tyrosine phosphatase type IVA, member 1	0.011
LOC100150997	similar to adenosine A1 receptor	0.011
grk1b	G protein-coupled receptor kinase 1 b	0.011
si:dkey-222f8.3	si:dkey-222f8.3	0.011
sb:cb307	sb:cb307	0.011
elna	elastin a	0.011
nptx2b	neuronal pentraxin 2b	0.011
dmbx1a	diencephalon/mesencephalon homeobox 1a	0.011
cebpg	CCAAT/enhancer binding protein (C/EBP), gamma	0.011
slc18a3b	solute carrier family 18 (vesicular acetylcholine), member 3b	0.011
gulp1	GULP, engulfment adaptor PTB domain containing 1	0.011
inha	inhibin, alpha	0.010
pdca	phosducin a	0.010
phlda1	pleckstrin homology-like domain, family A, member 1	0.010
fkbp5	FK506 binding protein 5	0.010
lasp1	LIM and SH3 protein 1	0.010
ahr1a	aryl hydrocarbon receptor 1a	0.010
tspo	translocator protein	0.010
zgc:136220	zgc:136220	0.010
aanat1	arylalkylamine N-acetyltransferase 1	0.010
si:dkey-3d4.3	si:dkey-3d4.3	0.010
si:dkeyp-72g9.4	si:dkeyp-72g9.4	0.010
casz1	castor zinc finger 1	0.010
LOC100150924	DNA polymerase subunit gamma-1-like	0.010
LOC559147	novel protein similar to vertebrate hairy and enhancer of split 2 (Drosophila) (HES2)	0.010
cx43	connexin 43	0.010
nppcl	natriuretic peptide precursor C-like protein	0.010
ldb3b	LIM domain binding 3b	0.010
zgc:152982	zgc:152982	0.010
ahrrb	aryl-hydrocarbon receptor repressor b	0.010