The network for 'negative regulation of transcription regulatory region dna binding' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of transcription regulatory region dna binding

Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.

NameDescriptionProbabilityFunc Analog Organism
osaCG7467 gene product from transcript CG7467-RD0.026
cwoclockwork orange0.019
Adf1Adh transcription factor 10.016
Ilp5Insulin-like peptide 50.016
fasfaint sausage0.015
tlkTousled-like kinase0.014
l(2)k14505lethal (2) k145050.014
Nf1Neurofibromin 10.014
CG14966CG14966 gene product from transcript CG14966-RA0.013
RdlResistant to dieldrin0.012
Fas3Fasciclin 30.012
RpL19Ribosomal protein L190.012
ns2nucleostemin 20.012
RagACG11968 gene product from transcript CG11968-RA0.012
RpL24-likeRibosomal protein L24-like0.011
CG9769CG9769 gene product from transcript CG9769-RA0.011
Hsc70-3Heat shock protein cognate 30.010
pdm2POU domain protein 20.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ZNF43zinc finger protein 430.827
ZNF253zinc finger protein 2530.345
TAL1T-cell acute lymphocytic leukemia 10.183
ZNF273zinc finger protein 2730.173
NCOR1nuclear receptor corepressor 10.168
ZNF675zinc finger protein 6750.089
ZNF117zinc finger protein 1170.053
ZNF254zinc finger protein 2540.037
ZNF93zinc finger protein 930.036
ZNF91zinc finger protein 910.032
ZNF430zinc finger protein 4300.026
ZNF85zinc finger protein 850.022
ZNF708zinc finger protein 7080.017
SKILSKI-like oncogene0.017
ANXA7annexin A70.015
ZNF680zinc finger protein 6800.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Per2period homolog 2 (Drosophila)0.830
Cry2cryptochrome 2 (photolyase-like)0.813
Otx2orthodenticle homolog 2 (Drosophila)0.803
Pax2paired box gene 20.673
Pitx2paired-like homeodomain transcription factor 20.447
Pax6paired box gene 60.373
Per1period homolog 1 (Drosophila)0.333
Gata4GATA binding protein 40.250
Fgf8fibroblast growth factor 80.207
Emx1empty spiracles homolog 1 (Drosophila)0.170
Hand1heart and neural crest derivatives expressed transcript 10.163
Hand2heart and neural crest derivatives expressed transcript 20.147
Emx2empty spiracles homolog 2 (Drosophila)0.142
Arntlaryl hydrocarbon receptor nuclear translocator-like0.105
Hes5hairy and enhancer of split 5 (Drosophila)0.084
Clockcircadian locomotor output cycles kaput0.077
Foxc2forkhead box C20.076
Tcfap2atranscription factor AP-2, alpha0.070
Cry1cryptochrome 1 (photolyase-like)0.068
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.065
Ntf3neurotrophin 30.065
Atoh7atonal homolog 7 (Drosophila)0.051
Isl1ISL1 transcription factor, LIM/homeodomain0.047
Pou4f2POU domain, class 4, transcription factor 20.038
Pax3paired box gene 30.036
Gli3GLI-Kruppel family member GLI30.036
Usp2ubiquitin specific peptidase 20.033
Nr2e1nuclear receptor subfamily 2, group E, member 10.032
Foxc1forkhead box C10.031
Kiss1rKISS1 receptor0.031
Rspo2R-spondin 2 homolog (Xenopus laevis)0.029
Hey2hairy/enhancer-of-split related with YRPW motif 20.027
Osr1odd-skipped related 1 (Drosophila)0.026
Gscgoosecoid homeobox0.026
Ascl1achaete-scute complex homolog 1 (Drosophila)0.025
Sox2SRY-box containing gene 20.024
Eya1eyes absent 1 homolog (Drosophila)0.024
Tal1T-cell acute lymphocytic leukemia 10.024
En1engrailed 10.022
Mab21l2mab-21-like 2 (C. elegans)0.021
Coro1bcoronin, actin binding protein 1B0.020
Lef1lymphoid enhancer binding factor 10.020
Sox10SRY-box containing gene 100.019
Neurod1neurogenic differentiation 10.019
Lhx1LIM homeobox protein 10.018
Lhx9LIM homeobox protein 90.017
Neurog2neurogenin 20.016
Shhsonic hedgehog0.016
Gbx2gastrulation brain homeobox 20.016
Per3period homolog 3 (Drosophila)0.016
Ldb2LIM domain binding 20.016
Nr5a1nuclear receptor subfamily 5, group A, member 10.015
Hey1hairy/enhancer-of-split related with YRPW motif 10.015
Pold1polymerase (DNA directed), delta 1, catalytic subunit0.014
Msx2homeobox, msh-like 20.014
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.013
Tbx3T-box 30.012
Alx4aristaless-like homeobox 40.011
Msx1homeobox, msh-like 10.011
Dlx5distal-less homeobox 50.011
Dlx2distal-less homeobox 20.011
Lhx3LIM homeobox protein 30.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cdh5cadherin 50.446
Sox18SRY (sex determining region Y)-box 180.176
Fgf1fibroblast growth factor 10.147
Slc23a1solute carrier family 23 (nucleobase transporters), member 10.125
Sox7SRY (sex determining region Y)-box 70.113
Gpr116G protein-coupled receptor 1160.107
Pou3f2POU class 3 homeobox 20.105
Mef2dmyocyte enhancer factor 2D0.090
P2ry4pyrimidinergic receptor P2Y, G-protein coupled, 40.087
Ptprhprotein tyrosine phosphatase, receptor type, H0.085
Ceacam1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)0.080
Ugt2a1UDP glucuronosyltransferase 2 family, polypeptide A10.076
Foxe1forkhead box E1 (thyroid transcription factor 2)0.066
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.057
Slc9a3solute carrier family 9 (sodium/hydrogen exchanger), member 30.055
Ppp1r3bprotein phosphatase 1, regulatory (inhibitor) subunit 3B0.053
Hes5hairy and enhancer of split 5 (Drosophila)0.049
Gja5gap junction protein, alpha 50.049
Nos3nitric oxide synthase 3, endothelial cell0.049
Hnf4ahepatocyte nuclear factor 4, alpha0.047
Acot12acyl-CoA thioesterase 120.044
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.043
Fkbp3FK506 binding protein 30.042
Magmyelin-associated glycoprotein0.039
Cdacytidine deaminase0.037
Trib1tribbles homolog 1 (Drosophila)0.036
Mybpc1myosin binding protein C, slow type0.036
Adra2badrenergic, alpha-2B-, receptor0.035
Thrbthyroid hormone receptor beta0.035
Gata2GATA binding protein 20.034
Gsk3aglycogen synthase kinase 3 alpha0.034
Naaladl1N-acetylated alpha-linked acidic dipeptidase-like 10.034
Rdh2retinol dehydrogenase 20.034
Hrghistidine-rich glycoprotein0.033
G6pcglucose-6-phosphatase, catalytic subunit0.032
Il1r1interleukin 1 receptor, type I0.031
BokBCL2-related ovarian killer0.030
Slc22a6solute carrier family 22 (organic anion transporter), member 60.029
Acox3acyl-Coenzyme A oxidase 3, pristanoyl0.028
Acox2acyl-Coenzyme A oxidase 2, branched chain0.027
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.026
Capn9calpain 90.026
Nlrp6NLR family, pyrin domain containing 60.025
RGD1304644similar to RIKEN cDNA 2310046K010.025
Cyp4f4cytochrome P450, family 4, subfamily f, polypeptide 40.024
Muc4mucin 4, cell surface associated0.024
Dhdpsldihydrodipicolinate synthase-like, mitochondrial0.024
Ebna1bp2EBNA1 binding protein 20.024
Olr837olfactory receptor 8370.023
Pklrpyruvate kinase, liver and RBC0.023
Rpl22l1ribosomal protein L22 like 10.022
Tac2tachykinin 20.022
Nmuneuromedin U0.022
Hipk3homeodomain interacting protein kinase 30.021
Crybb1crystallin, beta B10.021
Foxe3forkhead box E30.021
Pparaperoxisome proliferator activated receptor alpha0.021
Prlrprolactin receptor0.021
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.020
MpndMPN domain containing0.020
Acacbacetyl-Coenzyme A carboxylase beta0.020
Esr1estrogen receptor 10.020
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.020
Cgaglycoprotein hormones, alpha polypeptide0.020
Edn2endothelin 20.020
Gabrr1gamma-aminobutyric acid (GABA) receptor, rho 10.020
Cyp4b1cytochrome P450, family 4, subfamily b, polypeptide 10.019
Slc22a3solute carrier family 22 (extraneuronal monoamine transporter), member 30.019
DaoD-amino-acid oxidase0.019
TekTEK tyrosine kinase, endothelial0.019
Hspa1lheat shock protein 1-like0.019
Ppardperoxisome proliferator-activated receptor delta0.018
Sox13SRY (sex determining region Y)-box 130.018
Crct1cysteine-rich C-terminal 10.018
Hsd17b6hydroxysteroid (17-beta) dehydrogenase 60.018
Mettl7bmethyltransferase like 7B0.018
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.018
Ppypancreatic polypeptide0.017
Xpnpep2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound0.017
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.017
Fmo1flavin containing monooxygenase 10.017
Uchl3ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)0.017
RGD1311634similar to RIKEN cDNA 3200002M190.017
Akp3alkaline phosphatase 3, intestine, not Mn requiring0.017
Prkcaprotein kinase C, alpha0.017
Tomm5translocase of outer mitochondrial membrane 5 homolog (yeast)0.017
Epas1endothelial PAS domain protein 10.017
Pld1phospholipase D10.017
Arhgef15Rho guanine nucleotide exchange factor (GEF) 150.017
Tpothyroid peroxidase0.017
Icam2intercellular adhesion molecule 20.016
Slco2a1solute carrier organic anion transporter family, member 2a10.016
Pdcd5programmed cell death 50.016
Mucdhlmucin and cadherin like0.016
Hsd17b2hydroxysteroid (17-beta) dehydrogenase 20.016
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism