The network for 'histone exchange' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

histone exchange

The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits.

NameDescriptionProbabilityFunc Analog Organism
His2AvHistone H2A variant0.720
reptreptin0.337
Bap55Brahma associated protein 55kD0.331
SelDSelenide,water dikinase0.282
CG1240CG1240 gene product from transcript CG1240-RA0.235
CG3363CG3363 gene product from transcript CG3363-RB0.159
D1D1 chromosomal protein0.146
Snr1Snf5-related 10.145
CSN6COP9 complex homolog subunit 60.139
Su(var)205Suppressor of variegation 2050.075
Hrb98DEHeterogeneous nuclear ribonucleoprotein at 98DE0.073
Chd1Chromodomain-helicase-DNA-binding protein 10.070
CG6693CG6693 gene product from transcript CG6693-RA0.064
MRG15CG6363 gene product from transcript CG6363-RA0.057
msl-3male-specific lethal 30.051
SceSex combs extra0.047
Caf1Chromatin assembly factor 1 subunit0.040
nopono poles0.038
His3.3BHistone H3.3B0.038
CG9018CG9018 gene product from transcript CG9018-RA0.038
thoc5CG2980 gene product from transcript CG2980-RA0.038
cavcaravaggio0.037
Prp8pre-mRNA processing factor 80.036
Tango6Transport and Golgi organization 60.033
Kmn1kinetochore Mis12-Ndc80 network component 10.033
Mi-2CG8103 gene product from transcript CG8103-RA0.031
CG10267CG10267 gene product from transcript CG10267-RB0.030
Cdc37CG12019 gene product from transcript CG12019-RA0.029
Apc10Anaphase promoting complex subunit 100.028
asf1anti-silencing factor 10.028
CG15443CG15443 gene product from transcript CG15443-RA0.026
CG14213CG14213 gene product from transcript CG14213-RB0.026
ash1absent, small, or homeotic discs 10.026
Su(var)3-7Suppressor of variegation 3-70.025
SMC2CG10212 gene product from transcript CG10212-RA0.024
pr-set7CG3307 gene product from transcript CG3307-RC0.024
Aos1CG12276 gene product from transcript CG12276-RA0.024
Pp4-19CProtein phosphatase 19C0.023
Uch-L3Ubiquitin C-terminal hydrolase0.022
CG5933CG5933 gene product from transcript CG5933-RA0.021
Rbp1RNA-binding protein 10.021
CG1218CG1218 gene product from transcript CG1218-RA0.020
CTCFCG8591 gene product from transcript CG8591-RA0.020
Spt5CG7626 gene product from transcript CG7626-RA0.019
snamasomething that sticks like glue0.019
Hpr1CG2031 gene product from transcript CG2031-RA0.019
DMAP1CG11132 gene product from transcript CG11132-RA0.019
Nuf2CG8902 gene product from transcript CG8902-RA0.018
Grip75CG6176 gene product from transcript CG6176-RA0.018
Dcp1Decapping protein 10.018
SuURSuppressor of Under-Replication0.018
CG16734CG16734 gene product from transcript CG16734-RD0.017
CG12470CG12470 gene product from transcript CG12470-RA0.017
CoproxCoproporphyrinogen oxidase0.017
CG4400CG4400 gene product from transcript CG4400-RA0.016
CG12343CG12343 gene product from transcript CG12343-RA0.016
hanghangover0.016
Hdac3Histone deacetylase 30.015
RavusCG15889 gene product from transcript CG15889-RA0.015
CG7045CG7045 gene product from transcript CG7045-RA0.015
mfrmisfire0.015
domdomino0.015
MED31Mediator complex subunit 310.015
snfsans fille0.015
YL-1CG4621 gene product from transcript CG4621-RA0.015
morguemodifier of rpr and grim, ubiquitously expressed0.015
Su(var)2-HP2CG12864 gene product from transcript CG12864-RB0.014
Lim3CG10699 gene product from transcript CG10699-RB0.014
ktokohtalo0.014
CG13245CG13245 gene product from transcript CG13245-RA0.014
CG2608CG2608 gene product from transcript CG2608-RA0.014
CG10326CG10326 gene product from transcript CG10326-RA0.014
CG6066CG6066 gene product from transcript CG6066-RA0.013
djdon juan0.013
CG18004CG18004 gene product from transcript CG18004-RB0.013
WRNexoWRN exonuclease0.013
srpk79Dserine-arginine protein kinase at 79D0.013
endoBendophilin B0.013
Dpy-30L1Dpy-30-like 10.013
CG9601CG9601 gene product from transcript CG9601-RA0.013
jigr1jing interacting gene regulatory 10.013
Paf-AHalphaPlatelet-activating factor acetylhydrolase alpha0.013
CG12259CG12259 gene product from transcript CG12259-RA0.013
MED1Mediator complex subunit 10.013
Atac1ATAC component 10.012
msl-2male-specific lethal 20.012
klhl10CG12423 gene product from transcript CG12423-RB0.012
HP4Heterochromatin protein 40.012
TH1CG9984 gene product from transcript CG9984-RA0.012
CG7593CG7593 gene product from transcript CG7593-RA0.012
HiraCG12153 gene product from transcript CG12153-RA0.012
E(bx)Enhancer of bithorax0.012
CG32418CG32418 gene product from transcript CG32418-RA0.012
FLASHFLASH ortholog0.012
HcfHost cell factor0.011
HBS1CG1898 gene product from transcript CG1898-RA0.011
CG17261CG17261 gene product from transcript CG17261-RA0.011
snRNP-U1-70Ksmall ribonucleoprotein particle U1 subunit 70K0.011
Cyt-c-dCytochrome c distal0.011
RfC3Replication factor C subunit 30.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
RUVBL1RuvB-like 1 (E. coli)1.000
YY1YY1 transcription factor0.999
ACTL6Aactin-like 6A0.999
CHAF1Achromatin assembly factor 1, subunit A (p150)0.985
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.903
DPCDdeleted in primary ciliary dyskinesia homolog (mouse)0.866
C20orf20chromosome 20 open reading frame 200.839
VPS72vacuolar protein sorting 72 homolog (S. cerevisiae)0.806
MRFAP1Morf4 family associated protein 10.712
INO80EINO80 complex subunit E0.625
BAZ1Abromodomain adjacent to zinc finger domain, 1A0.585
INO80INO80 homolog (S. cerevisiae)0.557
ACTR5ARP5 actin-related protein 5 homolog (yeast)0.510
TRRAPtransformation/transcription domain-associated protein0.462
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.405
BAZ1Bbromodomain adjacent to zinc finger domain, 1B0.392
MORF4L2mortality factor 4 like 20.389
HNRNPA3heterogeneous nuclear ribonucleoprotein A30.249
CHAF1Bchromatin assembly factor 1, subunit B (p60)0.247
CDAN1congenital dyserythropoietic anemia, type I0.245
TLK1tousled-like kinase 10.242
ANP32Aacidic (leucine-rich) nuclear phosphoprotein 32 family, member A0.231
SETSET nuclear oncogene0.203
CHRAC1chromatin accessibility complex 10.174
HDAC2histone deacetylase 20.142
MRFAP1L1Morf4 family associated protein 1-like 10.140
CENPAcentromere protein A0.140
HMGB2high mobility group box 20.138
NUP153nucleoporin 153kDa0.126
RPA1replication protein A1, 70kDa0.123
CDR2cerebellar degeneration-related protein 2, 62kDa0.107
ACTR8ARP8 actin-related protein 8 homolog (yeast)0.106
TTI1Tel2 interacting protein 1 homolog (S. pombe)0.106
KAT2AK(lysine) acetyltransferase 2A0.100
POLEpolymerase (DNA directed), epsilon0.099
EP400E1A binding protein p4000.092
CBX5chromobox homolog 50.090
PIH1D1PIH1 domain containing 10.089
MSH6mutS homolog 6 (E. coli)0.078
NFRKBnuclear factor related to kappaB binding protein0.077
INO80DINO80 complex subunit D0.057
DMC1DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)0.056
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.055
PTMAprothymosin, alpha0.054
ASF1BASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.053
MORF4L1mortality factor 4 like 10.053
NUCKS1nuclear casein kinase and cyclin-dependent kinase substrate 10.053
INO80CINO80 complex subunit C0.053
TOP2Btopoisomerase (DNA) II beta 180kDa0.052
KAT5K(lysine) acetyltransferase 50.049
BCLAF1BCL2-associated transcription factor 10.048
POLE4polymerase (DNA-directed), epsilon 4 (p12 subunit)0.047
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.044
ATXN7ataxin 70.043
HMGB1high mobility group box 10.042
DEKDEK oncogene0.042
DMAP1DNA methyltransferase 1 associated protein 10.041
H2AFVH2A histone family, member V0.040
USP1ubiquitin specific peptidase 10.039
RAD21RAD21 homolog (S. pombe)0.037
ANP32Bacidic (leucine-rich) nuclear phosphoprotein 32 family, member B0.037
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 50.036
SLBPstem-loop binding protein0.035
SUZ12suppressor of zeste 12 homolog (Drosophila)0.035
CREB1cAMP responsive element binding protein 10.034
INO80BINO80 complex subunit B0.034
RSF1remodeling and spacing factor 10.033
TAF4TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa0.032
RUVBL2RuvB-like 2 (E. coli)0.032
H2AFZH2A histone family, member Z0.031
FBLfibrillarin0.030
DUTdeoxyuridine triphosphatase0.030
YAF2YY1 associated factor 20.029
RRM1ribonucleotide reductase M10.029
PRMT1protein arginine methyltransferase 10.028
PPIHpeptidylprolyl isomerase H (cyclophilin H)0.028
HMGN2high mobility group nucleosomal binding domain 20.028
MAXMYC associated factor X0.027
FOXM1forkhead box M10.027
FBXW7F-box and WD repeat domain containing 70.025
MCRS1microspherule protein 10.025
ACTR6ARP6 actin-related protein 6 homolog (yeast)0.025
PRRC2Cproline-rich coiled-coil 2C0.024
TLK2tousled-like kinase 20.023
ZNF267zinc finger protein 2670.023
TOP1topoisomerase (DNA) I0.022
SUMO4SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)0.022
NASPnuclear autoantigenic sperm protein (histone-binding)0.022
PSIP1PC4 and SFRS1 interacting protein 10.022
CBX1chromobox homolog 10.021
UBN1ubinuclein 10.021
FDFT1farnesyl-diphosphate farnesyltransferase 10.021
BIN1bridging integrator 10.021
KPNA6karyopherin alpha 6 (importin alpha 7)0.021
PRPS1phosphoribosyl pyrophosphate synthetase 10.020
TFPTTCF3 (E2A) fusion partner (in childhood Leukemia)0.020
RBBP4retinoblastoma binding protein 40.020
NRIP1nuclear receptor interacting protein 10.020
KHDRBS1KH domain containing, RNA binding, signal transduction associated 10.020
SRP9signal recognition particle 9kDa0.019
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Dmap1DNA methyltransferase 1-associated protein 10.289
H3f3aH3 histone, family 3A0.192
Esr1estrogen receptor 1 (alpha)0.064
Ep400E1A binding protein p4000.048
Kiss1KiSS-1 metastasis-suppressor0.047
Hmgb1high mobility group box 10.039
Hist1h1chistone cluster 1, H1c0.038
Pou5f1POU domain, class 5, transcription factor 10.038
Kat5K(lysine) acetyltransferase 50.038
Bglapbone gamma carboxyglutamate protein0.034
Amhr2anti-Mullerian hormone type 2 receptor0.022
Cgaglycoprotein hormones, alpha subunit0.019
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.018
Hist1h2brhistone cluster 1 H2br0.017
Pax8paired box gene 80.013
Duox2dual oxidase 20.012
Nucks1nuclear casein kinase and cyclin-dependent kinase substrate 10.011
Hist1h2bphistone cluster 1, H2bp0.011
Cdk1cyclin-dependent kinase 10.011
H2afzH2A histone family, member Z0.011
Baz1abromodomain adjacent to zinc finger domain 1A0.010
MaxMax protein0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ARP4Arp4p0.995
SWC4Swc4p0.990
SWR1Swr1p0.980
BDF1Bdf1p0.964
SWC3Swc3p0.962
EPL1Epl1p0.907
SWC5Swc5p0.773
VPS71Vps71p0.763
YAF9Yaf9p0.609
VPS72Vps72p0.565
ISW1Isw1p0.511
TRA1Tra1p0.251
ARP6Arp6p0.248
RVB2Rvb2p0.234
RSC8Rsc8p0.224
MOT1Mot1p0.153
ADA2Ada2p0.152
RSC4Rsc4p0.147
IES1Ies1p0.146
SWC7Swc7p0.144
TAF6Taf6p0.135
RSC2Rsc2p0.135
NGG1Ngg1p0.128
RCO1Rco1p0.119
SPT8Spt8p0.096
YTA7Yta7p0.077
RLF2Rlf2p0.076
SWI1Swi1p0.074
NHP10Nhp10p0.069
SET3Set3p0.067
SPT7Spt7p0.063
STH1Sth1p0.061
NTO1Nto1p0.061
SPT15Spt15p0.053
CHD1Chd1p0.051
GCN5Gcn5p0.050
HHT1Hht1p0.050
HDA2Hda2p0.047
ARP7Arp7p0.044
HTZ1Htz1p0.041
EAF1Eaf1p0.037
LEO1Leo1p0.035
RSC9Rsc9p0.033
RVB1Rvb1p0.032
RSC3Rsc3p0.029
RSC6Rsc6p0.029
HIR2Hir2p0.027
RSC30Rsc30p0.025
UME1Ume1p0.025
SUM1Sum1p0.025
IOC2Ioc2p0.024
UBP8Ubp8p0.024
NPL6Npl6p0.023
IOC3Ioc3p0.023
ARP8Arp8p0.022
CAC2Cac2p0.021
SPT20Spt20p0.021
EAF6Eaf6p0.020
INO80Ino80p0.020
SRD1Srd1p0.020
PRS2Prs2p0.020
ARP9Arp9p0.019
SUS1Sus1p0.019
SNF11Snf11p0.018
SPT10Spt10p0.018
YLR264C-Ahypothetical protein0.017
YOL038C-Ahypothetical protein0.017
LEU2Leu2p0.017
SET1Set1p0.017
RSC58Rsc58p0.016
HHT2Hht2p0.016
YLR162Whypothetical protein0.016
CKB1Ckb1p0.016
SAS4Sas4p0.016
HXT3Hxt3p0.016
IES6Ies6p0.016
CRP1Crp1p0.016
SCT1Sct1p0.015
MER1Mer1p0.015
SET2Set2p0.015
HOHop0.015
YIR035Chypothetical protein0.014
TAF12Taf12p0.014
SPL2Spl2p0.014
RTF1Rtf1p0.014
ATP6Atp6p0.014
YLR042Chypothetical protein0.014
ARP10Arp10p0.014
OPT2Opt2p0.013
CHA1Cha1p0.013
YAR068Whypothetical protein0.013
YPR157Whypothetical protein0.013
ARG8Arg8p0.013
GBP2Gbp2p0.013
REV1Rev1p0.013
ZPS1Zps1p0.013
RIF1Rif1p0.013
YIL151Chypothetical protein0.013
SCY1Scy1p0.013
NUP170Nup170p0.013