The network for 'ectopic germ cell programmed cell death' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

ectopic germ cell programmed cell death

Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.

NameDescriptionProbabilityFunc Analog Organism
parkparkin0.789
p53CG33336 gene product from transcript CG33336-RB0.789
Dcp-1Death caspase-10.720
debcldeath executioner Bcl-2 homologue0.633
imdimmune deficiency0.357
Sox14Sox box protein 140.324
ththread0.318
BG4CG12297 gene product from transcript CG12297-RA0.232
locolocomotion defects0.167
RelRelish0.152
grimCG4345 gene product from transcript CG4345-RA0.133
CG11347CG11347 gene product from transcript CG11347-RE0.087
HtrA2CG8464 gene product from transcript CG8464-RA0.086
cathDCG1548 gene product from transcript CG1548-RA0.060
jarjaguar0.053
AGO2Argonaute 20.050
ird1immune response deficient 10.037
Vrp1Verprolin 10.036
CG6751CG6751 gene product from transcript CG6751-RA0.028
CG5741CG5741 gene product from transcript CG5741-RC0.026
alphaTub84Balpha-Tubulin at 84B0.022
ird5immune response deficient 50.020
sklsickle0.020
maelmaelstrom0.019
djdon juan0.018
mfrnmitoferrin0.017
CG7856CG7856 gene product from transcript CG7856-RA0.017
Pvf2PDGF- and VEGF-related factor 20.017
ArkApaf-1-related-killer0.016
RASSF8CG5053 gene product from transcript CG5053-RA0.016
mus201mutagen-sensitive 2010.016
yuriyuri gagarin0.015
rprreaper0.014
EndoGEndonuclease G0.014
CG4287CG4287 gene product from transcript CG4287-RB0.012
CG12214CG12214 gene product from transcript CG12214-RB0.011
RnrLRibonucleoside diphosphate reductase large subunit0.011
Cyt-c-dCytochrome c distal0.011
LaspCG3849 gene product from transcript CG3849-RB0.010
painpainless0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.988
Kitkit oncogene0.984
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.926
BaxBCL2-associated X protein0.607
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.495
Bcl2B-cell leukemia/lymphoma 20.443
Kdrkinase insert domain protein receptor0.340
Itgb1integrin beta 1 (fibronectin receptor beta)0.330
Ptenphosphatase and tensin homolog0.283
Ctnnb1catenin (cadherin associated protein), beta 10.242
Nos3nitric oxide synthase 3, endothelial cell0.241
Kitlkit ligand0.230
Rb1retinoblastoma 10.184
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.172
Trp63transformation related protein 630.158
Tgfb1transforming growth factor, beta 10.134
Csf1colony stimulating factor 1 (macrophage)0.130
Flt4FMS-like tyrosine kinase 40.126
Apcadenomatosis polyposis coli0.124
Pmaip1phorbol-12-myristate-13-acetate-induced protein 10.114
Vhlvon Hippel-Lindau tumor suppressor0.094
Mitfmicrophthalmia-associated transcription factor0.093
Vegfavascular endothelial growth factor A0.082
Gbp5guanylate binding protein 50.073
Meox2mesenchyme homeobox 20.072
Tgfbr2transforming growth factor, beta receptor II0.061
Psen1presenilin 10.059
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.059
Nlrp3NLR family, pyrin domain containing 30.056
Il18interleukin 180.055
Lystlysosomal trafficking regulator0.055
Il1ainterleukin 1 alpha0.051
Ldlrlow density lipoprotein receptor0.046
Ednrbendothelin receptor type B0.046
Mdm2transformed mouse 3T3 cell double minute 20.041
Lyz2lysozyme 20.041
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.041
Fgfr2fibroblast growth factor receptor 20.037
Il6stinterleukin 6 signal transducer0.037
Ptch1patched homolog 10.035
Huwe1HECT, UBA and WWE domain containing 10.034
FasFas (TNF receptor superfamily member 6)0.033
Smad4MAD homolog 4 (Drosophila)0.027
Trp73transformation related protein 730.027
Vegfcvascular endothelial growth factor C0.026
Bak1BCL2-antagonist/killer 10.026
Birc3baculoviral IAP repeat-containing 30.026
Il1binterleukin 1 beta0.025
Cdkn2acyclin-dependent kinase inhibitor 2A0.024
Col1a1collagen, type I, alpha 10.023
Smad3MAD homolog 3 (Drosophila)0.022
Cdh5cadherin 50.022
C3ar1complement component 3a receptor 10.022
CblCasitas B-lineage lymphoma0.021
Pax3paired box gene 30.021
Plcg1phospholipase C, gamma 10.021
Zeb1zinc finger E-box binding homeobox 10.021
Cdk4cyclin-dependent kinase 40.020
Nf1neurofibromatosis 10.020
Sox9SRY-box containing gene 90.020
Apaf1apoptotic peptidase activating factor 10.019
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.019
Wt1Wilms tumor 1 homolog0.019
Itga3integrin alpha 30.018
Cyldcylindromatosis (turban tumor syndrome)0.018
Ccnd1cyclin D10.018
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.017
FaddFas (TNFRSF6)-associated via death domain0.016
Esr1estrogen receptor 1 (alpha)0.016
Hif1ahypoxia inducible factor 1, alpha subunit0.016
Lama5laminin, alpha 50.015
C1qtnf1C1q and tumor necrosis factor related protein 10.015
Rbl1retinoblastoma-like 1 (p107)0.015
BidBH3 interacting domain death agonist0.014
Foxc2forkhead box C20.014
Rxraretinoid X receptor alpha0.014
Atmataxia telangiectasia mutated homolog (human)0.014
Sprr2ksmall proline-rich protein 2K0.014
Cdx2caudal type homeobox 20.013
Ripk3receptor-interacting serine-threonine kinase 30.013
Cxcl2chemokine (C-X-C motif) ligand 20.012
Cd151CD151 antigen0.012
Cdkn1bcyclin-dependent kinase inhibitor 1B0.012
Casp7caspase 70.012
Msh2mutS homolog 2 (E. coli)0.012
Mlh1mutL homolog 1 (E. coli)0.012
Ets1E26 avian leukemia oncogene 1, 5' domain0.012
Notch2Notch gene homolog 2 (Drosophila)0.012
Mdm4transformed mouse 3T3 cell double minute 40.012
Irak4interleukin-1 receptor-associated kinase 40.011
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.011
Sgpl1sphingosine phosphate lyase 10.011
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.011
Cd14CD14 antigen0.010
Nfyanuclear transcription factor-Y alpha0.010
Cxcl12chemokine (C-X-C motif) ligand 120.010
Osmroncostatin M receptor0.010
Figfc-fos induced growth factor0.010
Tgfb2transforming growth factor, beta 20.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism