The network for 'regulation of response to oxidative stress' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of response to oxidative stress

Any process that modulates the frequency, rate or extent of response to oxidative stress.

NameDescriptionProbabilityFunc Analog Organism
Mekk1CG7717 gene product from transcript CG7717-RB0.400
CG8155CG8155 gene product from transcript CG8155-RA0.365
parkparkin0.274
S6kRPS6-p70-protein kinase0.243
chicoCG5686 gene product from transcript CG5686-RB0.237
Pink1PTEN-induced putative kinase 10.233
MTF-1Metal response element-binding Transcription Factor-10.223
Hsp27Heat shock protein 270.223
p120ctnAdherens junction protein p1200.202
Sod2Superoxide dismutase 2 (Mn)0.142
Hsp26Heat shock protein 260.133
Hsp68Heat shock protein 680.095
CatCatalase0.089
foxoforkhead box, sub-group O0.085
TBPHCG10327 gene product from transcript CG10327-RC0.082
mthmethuselah0.072
RicRas which interacts with Calmodulin0.069
kaykayak0.069
ParpPoly-(ADP-ribose) polymerase0.063
Hsp22Heat shock protein 220.062
NLazNeural Lazarillo0.061
TpiTriose phosphate isomerase0.060
Hsc70-4Heat shock protein cognate 40.057
hfwhalfway0.057
Ppat-DpckBifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase0.056
ThorCG8846 gene product from transcript CG8846-RA0.053
p38bCG7393 gene product from transcript CG7393-RA0.053
porinCG6647 gene product from transcript CG6647-RA0.050
Su(var)3-7Suppressor of variegation 3-70.048
DreddDeath related ced-3/Nedd2-like protein0.047
CG1021CG1021 gene product from transcript CG1021-RE0.043
LnkCG17367 gene product from transcript CG17367-RC0.041
slprslipper0.041
Hsp23Heat shock protein 230.040
dj-1betaCG1349 gene product from transcript CG1349-RA0.040
PgkPhosphoglycerate kinase0.039
certceramide transfer protein0.038
SdhBSuccinate dehydrogenase B0.038
DJ-1alphaCG6646 gene product from transcript CG6646-RA0.037
jarjaguar0.035
spasspastin0.034
enaenabled0.033
Mt2Methyltransferase 20.032
PargPoly(ADP-ribose) glycohydrolase0.032
hephemipterous0.032
Atf-2Activating transcription factor-20.031
AdarAdenosine deaminase acting on RNA0.030
ref(2)Prefractory to sigma P0.030
CadNCadherin-N0.029
GLazGlial Lazarillo0.029
CG30410CG30410 gene product from transcript CG30410-RB0.029
AldhAldehyde dehydrogenase0.028
RelRelish0.028
Trxr-1Thioredoxin reductase-10.028
Hsp70BaHeat-shock-protein-70Ba0.028
rprreaper0.027
ImpL2Ecdysone-inducible gene L20.027
Tom34Translocase of outer membrane 340.027
kek5kekkon50.027
slislit0.027
Lk6CG17342 gene product from transcript CG17342-RA0.027
simsingle-minded0.027
Sec61alphaCG9539 gene product from transcript CG9539-RA0.027
kermitCG11546 gene product from transcript CG11546-RB0.026
HcfHost cell factor0.026
whdwithered0.025
CG9232CG9232 gene product from transcript CG9232-RA0.025
rtrotated abdomen0.025
spinspinster0.024
liclicorne0.024
Surf1Surfeit 10.023
Trap1CG3152 gene product from transcript CG3152-RA0.023
cln3CG5582 gene product from transcript CG5582-RA0.023
p53CG33336 gene product from transcript CG33336-RB0.022
CG12370CG12370 gene product from transcript CG12370-RB0.022
mofmales absent on the first0.022
Traf6TNF-receptor-associated factor 60.022
DabDisabled0.021
CG8443CG8443 gene product from transcript CG8443-RA0.021
miltmilton0.020
l(3)82FdCG32464 gene product from transcript CG32464-RR0.020
Tak1TGF-beta activated kinase 10.019
Rab7Rab-protein 70.019
SnooSno oncogene0.019
mei-P26CG12218 gene product from transcript CG12218-RA0.019
HtrA2CG8464 gene product from transcript CG8464-RA0.019
mubmushroom-body expressed0.019
sesBstress-sensitive B0.019
Atg1Autophagy-specific gene 10.019
fhfrataxin homolog0.019
Dcr-2Dicer-20.018
CYLDcylindromatosis0.018
NFATNFAT homolog0.018
RhebCG1081 gene product from transcript CG1081-RA0.018
PP2A-B'CG7913 gene product from transcript CG7913-RK0.017
Ilp2Insulin-like peptide 20.017
CG31937CG31937 gene product from transcript CG31937-RA0.017
Khc-73Kinesin-730.017
Rab2Rab-protein 20.017
fs(2)ltoPP43female sterile (2) ltoPP430.017
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
igf1rbinsulin-like growth factor 1b receptor0.326
cyp3c1cytochrome P450, family 3, subfamily c, polypeptide 10.318
nrg2aneuregulin 2a0.295
gapdhglyceraldehyde-3-phosphate dehydrogenase0.290
vdravitamin D receptor a0.279
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.266
ptgs2aprostaglandin-endoperoxide synthase 2a0.266
socs3asuppressor of cytokine signaling 3a0.239
ctsl1acathepsin L, 1 a0.230
ptch2patched 20.228
myogmyogenin0.219
wnt10awingless-type MMTV integration site family, member 10a0.213
bcl2l1bcl2-like 10.213
mcl1amyeloid cell leukemia sequence 1a0.203
mapk6mitogen-activated protein kinase 60.187
hsp90a.1heat shock protein 90-alpha 10.175
mvpmajor vault protein0.171
mt2metallothionein 20.155
bactin1bactin10.153
sfrp1bsecreted frizzled-related protein 1b0.152
bidaBH3 interacting domain death agonist0.147
pafah1b1aplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a0.144
mapk3mitogen-activated protein kinase 30.144
adipor2adiponectin receptor 20.143
mmp9matrix metalloproteinase 90.142
sat1aspermidine/spermine N1-acetyltransferase 1a0.140
socs1suppressor of cytokine signaling 10.137
gstp1glutathione S-transferase pi0.136
sod1superoxide dismutase 1, soluble0.135
mapk14amitogen-activated protein kinase 14a0.132
ucp2uncoupling protein 20.130
sf1splicing factor 10.128
mcl1bmyeloid cell leukemia sequence 1b0.121
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.119
esr2aestrogen receptor 2a0.119
ntn2netrin 20.116
apoebapolipoprotein Eb0.112
gna12guanine nucleotide binding protein (G protein) alpha 120.111
socs3bsuppressor of cytokine signaling 3b0.108
fn1fibronectin 10.101
zgc:110343zgc:1103430.100
tm9sf2transmembrane 9 superfamily member 20.098
zgc:112180zgc:1121800.096
odc1ornithine decarboxylase 10.095
lmnalamin A0.095
junjun proto-oncogene0.093
cx45.6connexin 45.60.093
epas1bendothelial PAS domain protein 1b0.089
leprleptin receptor0.087
piwil2piwi-like 2 (Drosophila)0.085
zgc:112056zgc:1120560.080
clrn1clarin 10.079
park7parkinson disease (autosomal recessive, early onset) 70.077
mapk1mitogen-activated protein kinase 10.077
cacnb2acalcium channel, voltage-dependent, beta 2a0.074
tp53bp2tumor protein p53 binding protein, 20.073
sdcbpsyndecan binding protein (syntenin)0.072
nrg1neuregulin 10.071
keap1akelch-like ECH-associated protein 1a0.070
pdlim1PDZ and LIM domain 1 (elfin)0.069
acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.069
mapk4mitogen-activated protein kinase 40.069
myhz2myosin, heavy polypeptide 2, fast muscle specific0.068
nlgn1neuroligin 10.068
zgc:162944zgc:1629440.066
slc2a10solute carrier family 2 (facilitated glucose transporter), member 100.066
smarce1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.066
slc20a1bsolute carrier family 20, member 1b0.066
sqstm1sequestosome 10.063
dync1h1dynein, cytoplasmic 1, heavy chain 10.063
cd63Cd63 antigen0.061
copebcore promoter element binding protein0.060
antxr1anthrax toxin receptor 10.060
slc9a8solute carrier family 9 (sodium/hydrogen exchanger), member 80.058
rp2retinitis pigmentosa 2 (X-linked recessive)0.057
furinbfurin (paired basic amino acid cleaving enzyme) b0.056
aplp2amyloid beta (A4) precursor-like protein 20.056
kcnn1potassium intermediate/small conductance calcium-activated channel, subfamily N, member 10.056
insrbinsulin receptor b0.055
scn1basodium channel, voltage-gated, type I, beta a0.055
mapk7mitogen-activated protein kinase 70.055
baxabcl2-associated X protein, a0.055
hmga1ahigh mobility group AT-hook 1a0.054
sod2superoxide dismutase 2, mitochondrial0.053
cct6achaperonin containing TCP1, subunit 6A (zeta 1)0.053
fn1bfibronectin 1b0.051
ctbp2lC-terminal binding protein 2, like0.050
lppLIM domain containing preferred translocation partner in lipoma0.050
bbc3BCL2 binding component 30.049
crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.049
srsf6bserine/arginine-rich splicing factor 6b0.049
tjp2atight junction protein 2a (zona occludens 2)0.048
birc2baculoviral IAP repeat-containing 20.048
sgk1serum/glucocorticoid regulated kinase 10.048
col7a1lcollagen type VII alpha 1-like0.047
cnppd1cyclin Pas1/PHO80 domain containing 10.047
stac3SH3 and cysteine rich domain 30.046
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.046
sat1bspermidine/spermine N1-acetyl transferase 1b0.046
gfergrowth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)0.045
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BCL2L11BCL2-like 11 (apoptosis facilitator)0.902
BCL2L1BCL2-like 10.814
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.586
TRIB3tribbles homolog 3 (Drosophila)0.525
EGFRepidermal growth factor receptor0.436
PRDX1peroxiredoxin 10.404
SNTA1syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)0.350
SQSTM1sequestosome 10.314
INSRinsulin receptor0.281
BIDBH3 interacting domain death agonist0.266
GAS6growth arrest-specific 60.262
MAPTmicrotubule-associated protein tau0.206
BCL2B-cell CLL/lymphoma 20.195
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.188
BAK1BCL2-antagonist/killer 10.185
WBP4WW domain binding protein 4 (formin binding protein 21)0.175
BADBCL2-associated agonist of cell death0.168
DYNLL1dynein, light chain, LC8-type 10.153
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.152
IRS1insulin receptor substrate 10.137
PMLpromyelocytic leukemia0.137
APOEapolipoprotein E0.136
CSNK1A1casein kinase 1, alpha 10.130
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.127
PINK1PTEN induced putative kinase 10.127
FBXO7F-box protein 70.098
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)0.096
KEAP1kelch-like ECH-associated protein 10.095
BAXBCL2-associated X protein0.095
UBE3Aubiquitin protein ligase E3A0.093
DDIT3DNA-damage-inducible transcript 30.092
GAB1GRB2-associated binding protein 10.088
NFE2L2nuclear factor (erythroid-derived 2)-like 20.087
DAXXdeath-domain associated protein0.086
SFPQsplicing factor proline/glutamine-rich0.084
BAG3BCL2-associated athanogene 30.078
ZNF746zinc finger protein 7460.072
TOP1topoisomerase (DNA) I0.066
CRYABcrystallin, alpha B0.065
IRS2insulin receptor substrate 20.065
GSK3Bglycogen synthase kinase 3 beta0.065
NONOnon-POU domain containing, octamer-binding0.064
VHLvon Hippel-Lindau tumor suppressor0.061
NAMPTnicotinamide phosphoribosyltransferase0.061
RNR2l-rRNA0.058
MAP2K5mitogen-activated protein kinase kinase 50.057
ARNTaryl hydrocarbon receptor nuclear translocator0.055
HSPB8heat shock 22kDa protein 80.053
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.052
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.052
CPNE6copine VI (neuronal)0.051
NCOR2nuclear receptor corepressor 20.051
LOXL1lysyl oxidase-like 10.048
IGF1Rinsulin-like growth factor 1 receptor0.048
APOA1apolipoprotein A-I0.047
SNCAIPsynuclein, alpha interacting protein0.046
EGLN1egl nine homolog 1 (C. elegans)0.045
DUSP1dual specificity phosphatase 10.044
LTBP2latent transforming growth factor beta binding protein 20.044
FTLferritin, light polypeptide0.043
RNF144Bring finger protein 144B0.043
SNCAsynuclein, alpha (non A4 component of amyloid precursor)0.042
MAFFv-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)0.042
TGIF1TGFB-induced factor homeobox 10.040
HDAC1histone deacetylase 10.039
GRB10growth factor receptor-bound protein 100.039
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.035
MAP2K6mitogen-activated protein kinase kinase 60.035
PLAUplasminogen activator, urokinase0.034
MAPK14mitogen-activated protein kinase 140.033
PRDX4peroxiredoxin 40.033
CCDC6coiled-coil domain containing 60.032
PDIA4protein disulfide isomerase family A, member 40.032
PLXNB1plexin B10.032
PDIA3protein disulfide isomerase family A, member 30.031
APLP2amyloid beta (A4) precursor-like protein 20.031
HSPA1Bheat shock 70kDa protein 1B0.030
ERO1LERO1-like (S. cerevisiae)0.030
CALRcalreticulin0.030
FTH1ferritin, heavy polypeptide 10.029
SIN3ASIN3 homolog A, transcription regulator (yeast)0.029
EFTUD2elongation factor Tu GTP binding domain containing 20.029
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.028
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.028
BACH1BTB and CNC homology 1, basic leucine zipper transcription factor 10.028
PRKCAprotein kinase C, alpha0.028
APPamyloid beta (A4) precursor protein0.027
RAB5BRAB5B, member RAS oncogene family0.026
LRRK2leucine-rich repeat kinase 20.025
GHRgrowth hormone receptor0.025
FASFas (TNF receptor superfamily, member 6)0.025
MMS22LMMS22-like, DNA repair protein0.025
APOHapolipoprotein H (beta-2-glycoprotein I)0.024
HM13histocompatibility (minor) 130.024
MEF2Cmyocyte enhancer factor 2C0.024
POLR2Cpolymerase (RNA) II (DNA directed) polypeptide C, 33kDa0.024
CUL7cullin 70.023
NOGnoggin0.023
BANPBTG3 associated nuclear protein0.023
SOCS3suppressor of cytokine signaling 30.022
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.926
Mapk14mitogen-activated protein kinase 140.893
Apoeapolipoprotein E0.776
Loxlysyl oxidase0.704
BaxBCL2-associated X protein0.703
Trp53transformation related protein 530.688
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.565
Trib3tribbles homolog 3 (Drosophila)0.432
Vhlvon Hippel-Lindau tumor suppressor0.420
Tlr4toll-like receptor 40.418
Prnpprion protein0.376
Vegfavascular endothelial growth factor A0.363
Kitkit oncogene0.324
Cav1caveolin 1, caveolae protein0.312
Bcl2B-cell leukemia/lymphoma 20.283
Fbn1fibrillin 10.283
Ldlrlow density lipoprotein receptor0.245
Ppargperoxisome proliferator activated receptor gamma0.244
Ghrgrowth hormone receptor0.237
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.237
Ccl2chemokine (C-C motif) ligand 20.182
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.173
Ptenphosphatase and tensin homolog0.154
Grb10growth factor receptor bound protein 100.152
Mapkapk2MAP kinase-activated protein kinase 20.151
Stat3signal transducer and activator of transcription 30.142
Mapk11mitogen-activated protein kinase 110.139
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.119
Aebp1AE binding protein 10.116
Ltbp2latent transforming growth factor beta binding protein 20.114
Mfn2mitofusin 20.112
Tgfbr2transforming growth factor, beta receptor II0.104
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.103
Mmp2matrix metallopeptidase 20.100
Tenc1tensin like C1 domain-containing phosphatase0.093
Plxnd1plexin D10.085
Ep300E1A binding protein p3000.085
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.083
Bak1BCL2-antagonist/killer 10.081
Gab1growth factor receptor bound protein 2-associated protein 10.074
Agtr2angiotensin II receptor, type 20.074
Cryabcrystallin, alpha B0.073
Rps3ribosomal protein S30.071
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.071
Edn1endothelin 10.068
Ctsbcathepsin B0.068
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.067
Tlr2toll-like receptor 20.062
Pax3paired box gene 30.062
Cyldcylindromatosis (turban tumor syndrome)0.061
Cd44CD44 antigen0.059
Ece1endothelin converting enzyme 10.058
Svep1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 10.054
Prrx2paired related homeobox 20.054
Mmp9matrix metallopeptidase 90.053
Mitfmicrophthalmia-associated transcription factor0.052
Pmaip1phorbol-12-myristate-13-acetate-induced protein 10.051
Lrp1low density lipoprotein receptor-related protein 10.050
Tgfb1transforming growth factor, beta 10.050
Lystlysosomal trafficking regulator0.049
Ccr2chemokine (C-C motif) receptor 20.049
Lipalysosomal acid lipase A0.047
Thbs2thrombospondin 20.046
Aplp2amyloid beta (A4) precursor-like protein 20.046
Gpx1glutathione peroxidase 10.045
Spp1secreted phosphoprotein 10.044
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.044
Nfe2l2nuclear factor, erythroid derived 2, like 20.044
Smosmoothened homolog (Drosophila)0.044
Irs2insulin receptor substrate 20.044
Ifngr1interferon gamma receptor 10.041
Il6stinterleukin 6 signal transducer0.041
Fbln1fibulin 10.041
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.040
Fbln5fibulin 50.040
Il6interleukin 60.040
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.040
Mrc2mannose receptor, C type 20.039
Mkl2MKL/myocardin-like 20.039
Sqstm1sequestosome 10.037
Htra3HtrA serine peptidase 30.037
Bag3BCL2-associated athanogene 30.037
Pcolceprocollagen C-endopeptidase enhancer protein0.037
Mmp11matrix metallopeptidase 110.037
Igfbp6insulin-like growth factor binding protein 60.036
Lama5laminin, alpha 50.036
Gaaglucosidase, alpha, acid0.036
Mmp8matrix metallopeptidase 80.036
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.036
Sftpdsurfactant associated protein D0.035
Fxyd1FXYD domain-containing ion transport regulator 10.034
Tcn2transcobalamin 20.033
Arntlaryl hydrocarbon receptor nuclear translocator-like0.033
Emp2epithelial membrane protein 20.033
Plaaphospholipase A2, activating protein0.032
C5ar1complement component 5a receptor 10.031
Ptgs2prostaglandin-endoperoxide synthase 20.031
Nbl1neuroblastoma, suppression of tumorigenicity 10.031
Htra1HtrA serine peptidase 10.030
Gpx3glutathione peroxidase 30.029
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Psma2proteasome (prosome, macropain) subunit, alpha type 20.034
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism