The network for 'regulation of protein deacetylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of protein deacetylation

Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.

NameDescriptionProbabilityFunc Analog Organism
CtBPC-terminal Binding Protein0.618
Nop60BNucleolar protein at 60B0.115
JraJun-related antigen0.095
Tip60CG6121 gene product from transcript CG6121-RA0.093
Snr1Snf5-related 10.081
gcmglial cells missing0.070
TomTwin of m40.059
CG10107CG10107 gene product from transcript CG10107-RA0.058
Su(H)Suppressor of Hairless0.058
larkCG8597 gene product from transcript CG8597-RD0.055
XNPCG4548 gene product from transcript CG4548-RA0.054
l(2)05510lethal (2) 055100.054
Tm1Tropomyosin 10.051
sosine oculis0.045
pr-set7CG3307 gene product from transcript CG3307-RC0.042
Mi-2CG8103 gene product from transcript CG8103-RA0.041
SelDSelenide,water dikinase0.038
highikaru genki0.037
HLHm7E(spl) region transcript m70.036
Kr-h1Kruppel homolog 10.034
CG8709CG8709 gene product from transcript CG8709-RK0.034
DrefDNA replication-related element factor0.031
Mmp2Matrix metalloproteinase 20.029
reporeversed polarity0.029
sinaseven in absentia0.028
CG3847CG3847 gene product from transcript CG3847-RA0.028
His2AvHistone H2A variant0.026
CG7879CG7879 gene product from transcript CG7879-RB0.025
dwgdeformed wings0.025
myoglianinCG1838 gene product from transcript CG1838-RD0.024
HmgsHMG Coenzyme A synthase0.024
oddodd skipped0.023
Eps-15Epidermal growth factor receptor pathway substrate clone 150.023
ash2absent, small, or homeotic discs 20.022
Su(z)2Suppressor of zeste 20.022
CG9821CG9821 gene product from transcript CG9821-RB0.022
CG7379CG7379 gene product from transcript CG7379-RA0.021
stanstarry night0.020
swshort wing0.020
Rab30CG9100 gene product from transcript CG9100-RB0.019
GgaCG3002 gene product from transcript CG3002-RB0.019
CG10990CG10990 gene product from transcript CG10990-RB0.018
prodproliferation disrupter0.018
SF1Splicing factor 10.017
DadDaughters against dpp0.017
G-salpha60AG protein salpha 60A0.016
Tak1TGF-beta activated kinase 10.016
Hdac3Histone deacetylase 30.016
Srp54CG4602 gene product from transcript CG4602-RA0.016
TBPHCG10327 gene product from transcript CG10327-RC0.015
Pk92BProtein kinase at 92B0.015
CG7332CG7332 gene product from transcript CG7332-RA0.015
Hip14Huntingtin-interacting protein 140.015
E(spl)Enhancer of split0.015
AtuAnother transcription unit0.015
SosSon of sevenless0.014
HcfHost cell factor0.014
CG5439CG5439 gene product from transcript CG5439-RA0.014
Cdk8Cyclin-dependent kinase 80.014
CDC45LCG3658 gene product from transcript CG3658-RA0.014
CG8247CG8247 gene product from transcript CG8247-RB0.014
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
wnt5bwingless-type MMTV integration site family, member 5b0.043
rbfox2RNA binding protein, fox-1 homolog (C. elegans) 20.033
bonbonnie and clyde0.026
skianuclear oncoprotein skia0.026
cdh2cadherin 2, neuronal0.025
smad5MAD homolog 5 (Drosophila)0.025
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.023
axin2axin 2 (conductin, axil)0.023
brd4bromodomain containing 40.022
crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.022
rargaretinoic acid receptor gamma a0.021
pbx4pre-B-cell leukemia transcription factor 40.020
gpc4glypican 40.019
mibmind bomb0.019
ptpraprotein tyrosine phosphatase, receptor type, A0.018
gli1GLI-Kruppel family member 10.018
bmp1abone morphogenetic protein 1a0.018
lppLIM domain containing preferred translocation partner in lipoma0.018
tcf12transcription factor 120.017
dzip1DAZ interacting protein 10.017
smosmoothened homolog (Drosophila)0.016
npeppsaminopeptidase puromycin sensitive0.015
trim71tripartite motif-containing 710.015
nova2neuro-oncological ventral antigen 20.014
mknk2bMAP kinase-interacting serine/threonine kinase 2b0.013
LOC100536021spectrin beta chain, brain 1-like0.013
celsr1acadherin EGF LAG seven-pass G-type receptor 1a0.013
dync1h1dynein, cytoplasmic 1, heavy chain 10.013
metmet proto-oncogene (hepatocyte growth factor receptor)0.012
her1hairy-related 10.012
fn1fibronectin 10.012
tagln2transgelin 20.012
foxd3forkhead box D30.012
gsk3bglycogen synthase kinase 3 beta0.012
foxi2forkhead box I20.011
ctnnb1catenin (cadherin-associated protein), beta 10.011
prkciprotein kinase C, iota0.011
fzd9bfrizzled homolog 9b0.011
sox5SRY-box containing gene 50.011
dio2deiodinase, iodothyronine, type II0.011
lhx1bLIM homeobox 1b0.011
nphs2nephrosis 2, idiopathic, steroid-resistant (podocin)0.011
ephb4beph receptor B4b0.011
sox19aSRY-box containing gene 19a0.011
fgfr4fibroblast growth factor receptor 40.011
vaspvasodilator-stimulated phosphoprotein0.011
zeb2azinc finger E-box binding homeobox 2a0.010
sesn1sestrin 10.010
mapk6mitogen-activated protein kinase 60.010
abi1aabl-interactor 1a0.010
ppp2r5ebprotein phosphatase 2, regulatory subunit B', epsilon isoform b0.010
cart1cartilage paired-class homeoprotein 10.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SIN3ASIN3 homolog A, transcription regulator (yeast)0.775
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.730
HDAC1histone deacetylase 10.562
TGIF1TGFB-induced factor homeobox 10.281
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.257
SNTA1syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)0.190
CREBBPCREB binding protein0.181
JUNjun proto-oncogene0.139
NCOR2nuclear receptor corepressor 20.126
MDM2Mdm2 p53 binding protein homolog (mouse)0.123
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.101
HIPK2homeodomain interacting protein kinase 20.098
MAPK14mitogen-activated protein kinase 140.085
NCOR1nuclear receptor corepressor 10.085
SMAD3SMAD family member 30.078
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.067
VEGFAvascular endothelial growth factor A0.067
HDAC3histone deacetylase 30.061
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.061
ATF2activating transcription factor 20.057
RB1retinoblastoma 10.049
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.047
NR2E3nuclear receptor subfamily 2, group E, member 30.046
NRP1neuropilin 10.045
RUNX1runt-related transcription factor 10.038
MED15mediator complex subunit 150.037
EP300E1A binding protein p3000.033
ARRB1arrestin, beta 10.030
IRF2BP1interferon regulatory factor 2 binding protein 10.029
HDAC9histone deacetylase 90.027
ATF3activating transcription factor 30.026
CPNE6copine VI (neuronal)0.025
STAG2stromal antigen 20.024
HDAC5histone deacetylase 50.024
PMLpromyelocytic leukemia0.020
TBL1XR1transducin (beta)-like 1 X-linked receptor 10.018
PGFplacental growth factor0.018
SMAD4SMAD family member 40.018
BAZ2Bbromodomain adjacent to zinc finger domain, 2B0.017
CTBP2C-terminal binding protein 20.015
SP1Sp1 transcription factor0.015
MED25mediator complex subunit 250.014
ZNF148zinc finger protein 1480.014
DCAF7DDB1 and CUL4 associated factor 70.014
SMAD2SMAD family member 20.013
MAP3K1mitogen-activated protein kinase kinase kinase 10.013
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.012
LZTS2leucine zipper, putative tumor suppressor 20.012
UBR5ubiquitin protein ligase E3 component n-recognin 50.012
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.012
PGRprogesterone receptor0.012
SKIv-ski sarcoma viral oncogene homolog (avian)0.012
KAT2BK(lysine) acetyltransferase 2B0.011
COL5A1collagen, type V, alpha 10.011
CTBP1C-terminal binding protein 10.011
TBL1Xtransducin (beta)-like 1X-linked0.011
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.011
RARAretinoic acid receptor, alpha0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 531.000
JunJun oncogene0.992
Sin3atranscriptional regulator, SIN3A (yeast)0.984
Ptenphosphatase and tensin homolog0.970
Arid1aAT rich interactive domain 1A (SWI-like)0.962
Hdac1histone deacetylase 10.946
Vaspvasodilator-stimulated phosphoprotein0.835
Kat2aK(lysine) acetyltransferase 2A0.833
FosFBJ osteosarcoma oncogene0.685
EvlEna-vasodilator stimulated phosphoprotein0.580
Ncor1nuclear receptor co-repressor 10.503
Plin1perilipin 10.456
Mll1myeloid/lymphoid or mixed-lineage leukemia 10.420
Wfikkn2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.408
Enahenabled homolog (Drosophila)0.348
Csrp2bpcysteine and glycine-rich protein 2 binding protein0.338
Egr1early growth response 10.288
Sox2SRY-box containing gene 20.271
Yy1YY1 transcription factor0.257
Srfserum response factor0.220
Yeats2YEATS domain containing 20.202
Map3k7mitogen-activated protein kinase kinase kinase 70.190
Tnfaip3tumor necrosis factor, alpha-induced protein 30.190
DaxxFas death domain-associated protein0.188
Skiski sarcoma viral oncogene homolog (avian)0.168
Map3k8mitogen-activated protein kinase kinase kinase 80.166
Hdac7histone deacetylase 70.158
Zeb1zinc finger E-box binding homeobox 10.151
Tnftumor necrosis factor0.141
Wdr26WD repeat domain 260.134
Ighimmunoglobulin heavy chain complex0.133
Egr2early growth response 20.126
Rnf44ring finger protein 440.123
Morf4l1mortality factor 4 like 10.119
Mdm2transformed mouse 3T3 cell double minute 20.108
Plaurplasminogen activator, urokinase receptor0.105
Atf3activating transcription factor 30.103
Arid2AT rich interactive domain 2 (ARID, RFX-like)0.101
Yap1yes-associated protein 10.098
Ednraendothelin receptor type A0.097
5430411K18RikRIKEN cDNA 5430411K18 gene0.094
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.094
Nr4a1nuclear receptor subfamily 4, group A, member 10.093
Plxnd1plexin D10.091
Pmlpromyelocytic leukemia0.088
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.084
Mta2metastasis-associated gene family, member 20.084
Casp8caspase 80.083
Ncoa1nuclear receptor coactivator 10.082
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.080
Zfp362zinc finger protein 3620.080
Trp73transformation related protein 730.078
Smarcd1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.069
Smad7MAD homolog 7 (Drosophila)0.069
Cxcl2chemokine (C-X-C motif) ligand 20.067
Mdm4transformed mouse 3T3 cell double minute 40.067
Rhobras homolog gene family, member B0.062
Adamts1a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10.061
Zfp36zinc finger protein 360.061
Trraptransformation/transcription domain-associated protein0.060
Rc3h1RING CCCH (C3H) domains 10.058
Arhgef1Rho guanine nucleotide exchange factor (GEF) 10.058
Maffv-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)0.058
Cyr61cysteine rich protein 610.058
Rararetinoic acid receptor, alpha0.056
Sp1trans-acting transcription factor 10.054
Tgfbr1transforming growth factor, beta receptor I0.052
Fbxw7F-box and WD-40 domain protein 70.051
Notch1Notch gene homolog 1 (Drosophila)0.051
Runx1runt related transcription factor 10.051
FosbFBJ osteosarcoma oncogene B0.050
Tada3transcriptional adaptor 30.049
Actn1actinin, alpha 10.048
Klf4Kruppel-like factor 4 (gut)0.048
Ptgs2prostaglandin-endoperoxide synthase 20.047
Nfil3nuclear factor, interleukin 3, regulated0.047
Stat3signal transducer and activator of transcription 30.045
FaddFas (TNFRSF6)-associated via death domain0.045
Mll5myeloid/lymphoid or mixed-lineage leukemia 50.045
Nab2Ngfi-A binding protein 20.044
Klf6Kruppel-like factor 60.044
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.043
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.043
Ghrgrowth hormone receptor0.040
Dusp1dual specificity phosphatase 10.039
Rcor1REST corepressor 10.038
Elof1elongation factor 1 homolog (ELF1, S. cerevisiae)0.037
Pygo2pygopus 20.035
Basp1brain abundant, membrane attached signal protein 10.034
NanogNanog homeobox0.034
Kdm2blysine (K)-specific demethylase 2B0.034
Tbl1xtransducin (beta)-like 1 X-linked0.034
Mecp2methyl CpG binding protein 20.032
Grk6G protein-coupled receptor kinase 60.032
Sntb2syntrophin, basic 20.032
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism