The network for 'stem cell fate commitment' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

stem cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a stem cell.

NameDescriptionProbabilityFunc Analog Organism
rhorhomboid0.990
numbCG3779 gene product from transcript CG3779-RB0.989
aopanterior open0.982
spispitz0.972
E(spl)Enhancer of split0.959
wgwingless0.919
l(2)gllethal (2) giant larvae0.903
gcmglial cells missing0.823
HLHm7E(spl) region transcript m70.719
rapretina aberrant in pattern0.681
slislit0.662
SoxNSoxNeuro0.566
scascabrous0.513
malphaE(spl) region transcript malpha0.508
HLHmgammaE(spl) region transcript mgamma0.499
edechinoid0.498
HLHm5E(spl) region transcript m50.492
mammastermind0.460
brkbrinker0.413
stgstring0.397
bibbig brain0.389
amosabsent MD neurons and olfactory sensilla0.371
pntpointed0.363
ococelliless0.335
PcPolycomb0.306
UbxUltrabithorax0.297
Ras85DRas oncogene at 85D0.274
spdosanpodo0.266
scscute0.261
dadaughterless0.256
lealeak0.250
nkdnaked cuticle0.228
rorough0.228
senssenseless0.227
commcommissureless0.223
slp1sloppy paired 10.218
TomTwin of m40.215
arrarrow0.209
jingCG9397 gene product from transcript CG9397-RI0.204
roboroundabout0.194
snostrawberry notch0.193
gsbgooseberry0.193
emcextra macrochaetae0.192
Src64BSrc oncogene at 64B0.188
HLHmdeltaE(spl) region transcript mdelta0.185
ttktramtrack0.179
fasfaint sausage0.174
shgshotgun0.172
NNotch0.169
NotumCG13076 gene product from transcript CG13076-RB0.167
kuzkuzbanian0.165
midmidline0.162
m4E(spl) region transcript m40.161
Su(H)Suppressor of Hairless0.156
Cdc42CG12530 gene product from transcript CG12530-RA0.153
neurneuralized0.148
spospook0.146
inscinscuteable0.143
enengrailed0.134
kek1kekkon-10.127
enaenabled0.123
HLHmbetaE(spl) region transcript mbeta0.119
Wnt4Wnt oncogene analog 40.117
dpndeadpan0.110
gtgiant0.109
hkbhuckebein0.109
emsempty spiracles0.107
CG6954CG6954 gene product from transcript CG6954-RB0.103
fkhfork head0.102
foifear-of-intimacy0.101
egeagle0.100
sogshort gastrulation0.097
phlpole hole0.096
svpseven up0.095
LanALaminin A0.092
alaristaless0.089
miramiranda0.087
acachaete0.084
edlETS-domain lacking0.083
stanstarry night0.083
pnrpannier0.082
prosprospero0.078
bcdbicoid0.078
nctnicastrin0.075
simsingle-minded0.075
drmdrumstick0.074
Tre1trapped in endoderm-10.073
unc-5CG8166 gene product from transcript CG8166-RA0.071
phylphyllopod0.066
miminus0.065
atoatonal0.063
HHairless0.060
tlltailless0.059
locolocomotion defects0.058
abd-Aabdominal A0.056
ptcpatched0.055
KrnKeren0.055
hbhunchback0.054
ciccapicua0.053
runrunt0.053
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
elt-6Protein ELT-60.410
cnd-1Protein CND-10.402
nhr-67Protein NHR-670.363
ten-1Protein TEN-10.153
egl-18Protein EGL-180.146
hbl-1Protein HBL-10.118
egl-46Protein EGL-460.075
sel-8Protein SEL-80.072
unc-86Protein UNC-860.071
nhr-25Protein NHR-250.056
let-60Protein LET-600.055
hlh-14Protein HLH-140.053
rig-5Protein RIG-50.050
ceh-27Protein CEH-270.047
plc-3Protein PLC-30.041
hnd-1Protein HND-10.038
Y102A11A.6Protein Y102A11A.60.031
cam-1Protein CAM-10.025
hlh-2Protein HLH-20.023
sos-1Protein SOS-10.023
hmg-1.2Protein HMG-1.20.023
hlh-1Protein HLH-10.021
mec-4Protein MEC-40.019
nhr-111Protein NHR-1110.019
ref-2Protein REF-20.018
egl-38Protein EGL-380.018
lin-12Protein LIN-120.016
plx-1Protein PLX-10.016
unc-42Protein UNC-420.015
ahr-1Protein AHR-10.015
wrm-1Protein WRM-10.015
ins-2Protein INS-20.014
lag-2Protein LAG-20.014
T09B4.5Protein T09B4.50.013
egl-36Protein EGL-360.012
T25B9.3Protein T25B9.30.011
pry-1Protein PRY-10.011
nfyb-1Protein NFYB-10.011
tctn-1Protein TCTN-10.011
itr-1Protein ITR-10.010
ceh-16Protein CEH-160.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.988
ascl1aachaete-scute complex-like 1a (Drosophila)0.866
plp1aproteolipid protein 1a0.826
cdh2cadherin 2, neuronal0.781
notch1anotch homolog 1a0.766
dab1adisabled homolog 1a (Drosophila)0.651
brd2abromodomain-containing 2a0.596
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.559
neurod4neurogenic differentiation 40.530
neo1neogenin 10.481
dladeltaA0.473
vsx2visual system homeobox 20.439
otpborthopedia homolog b0.432
sox10SRY-box containing gene 100.427
pax6apaired box gene 6a0.398
dlbdeltaB0.388
nkx2.2aNK2 transcription factor related 2a0.379
erbb3av-erb-b2 erythroblastic leukemia viral oncogene homolog 3a0.376
lhx1aLIM homeobox 1a0.336
irx3biroquois homeobox protein 3b0.325
lmx1b.1LIM homeobox transcription factor 1, beta 10.316
ccnd1cyclin D10.307
pou5f1POU domain, class 5, transcription factor 10.302
scube2signal peptide, CUB domain, EGF-like 20.259
eya1eyes absent homolog 10.254
foxn4forkhead box N40.249
prdm16PR domain containing 160.236
nr2f2nuclear receptor subfamily 2, group F, member 20.236
cdx4caudal type homeo box transcription factor 40.221
eng2aengrailed 2a0.203
ascl1bachaete-scute complex-like 1b (Drosophila)0.199
dlddeltaD0.198
olig2oligodendrocyte lineage transcription factor 20.198
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.194
nr2e1nuclear receptor subfamily 2, group E, member 10.190
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.186
sox19aSRY-box containing gene 19a0.181
gbx2gastrulation brain homeo box 20.174
rorabRAR-related orphan receptor A, paralog b0.174
prdm5PR domain containing 50.170
dctdopachrome tautomerase0.169
pax8paired box gene 80.168
jag1bjagged 1b0.162
vsx1visual system homeobox 1 homolog, chx10-like0.159
neurodneurogenic differentiation0.153
sox32SRY-box containing gene 320.153
pcdh18bprotocadherin 18b0.148
phox2apaired-like homeobox 2a0.140
chrna2acholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)0.133
eng2bengrailed 2b0.129
hoxb1ahomeo box B1a0.125
mibmind bomb0.124
meis3myeloid ecotropic viral integration site 30.122
trim33tripartite motif-containing 330.122
fgf8bfibroblast growth factor 8 b0.119
tshbthyroid stimulating hormone, beta subunit0.118
mycamyelocytomatosis oncogene a0.118
gata3GATA-binding protein 30.118
foxd3forkhead box D30.117
neurog1neurogenin 10.114
wt1bwilms tumor 1b0.104
pou3f1POU class 3 homeobox 10.104
gbx1gastrulation brain homeobox 10.100
sox2SRY-box containing gene 20.098
pycardPYD and CARD domain containing0.097
egfraepidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)0.096
zic6zic family member 60.096
tp73tumor protein p730.096
tp53tumor protein p530.094
tbx16T-box gene 160.094
hgfahepatocyte growth factor a0.093
tm9sf2transmembrane 9 superfamily member 20.091
gfergrowth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)0.087
slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.085
wnt11wingless-type MMTV integration site family, member 110.084
chd7chromodomain helicase DNA binding protein 70.084
meis2.2myeloid ecotropic viral integration site 2.20.083
card14caspase recruitment domain family, member 140.082
dnmt3DNA (cytosine-5-)-methyltransferase 30.081
ccnb1cyclin B10.081
her3hairy-related 30.080
dmrt3adoublesex and mab-3 related transcription factor 3a0.079
gata2aGATA-binding protein 2a0.079
foxg1aforkhead box G1a0.077
brd2bbromodomain containing 2b0.077
rx3retinal homeobox gene 30.077
psen1presenilin 10.076
lamc1laminin, gamma 10.075
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.075
nrarpbnotch-regulated ankyrin repeat protein b0.074
zgc:101606zgc:1016060.074
otx2orthodenticle homolog 20.073
eng1bengrailed 1b0.073
dlg2discs, large (Drosophila) homolog 20.072
tal1T-cell acute lymphocytic leukemia 10.072
cldn12claudin 120.072
ccnb2cyclin B20.072
olig3oligodendrocyte transcription factor 30.071
egr2bearly growth response 2b0.071
bnc2basonuclin 20.069
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog0.965
Ctnnb1catenin (cadherin associated protein), beta 10.937
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.868
Hes1hairy and enhancer of split 1 (Drosophila)0.806
Isl1ISL1 transcription factor, LIM/homeodomain0.801
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.795
Pax6paired box gene 60.738
Fgfr2fibroblast growth factor receptor 20.718
Ntf3neurotrophin 30.709
Notch1Notch gene homolog 1 (Drosophila)0.594
Nrg1neuregulin 10.529
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.484
Otx2orthodenticle homolog 2 (Drosophila)0.471
Bdnfbrain derived neurotrophic factor0.426
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.396
Pax3paired box gene 30.396
Ptenphosphatase and tensin homolog0.384
Fgf8fibroblast growth factor 80.330
Neurod1neurogenic differentiation 10.302
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.267
Chd7chromodomain helicase DNA binding protein 70.228
Pitx2paired-like homeodomain transcription factor 20.223
Otx1orthodenticle homolog 1 (Drosophila)0.201
Neurog2neurogenin 20.198
Gli3GLI-Kruppel family member GLI30.190
Hand1heart and neural crest derivatives expressed transcript 10.183
Emx1empty spiracles homolog 1 (Drosophila)0.179
Msx2homeobox, msh-like 20.169
Retret proto-oncogene0.168
Itgb1integrin beta 1 (fibronectin receptor beta)0.160
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.142
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.141
Ptpn11protein tyrosine phosphatase, non-receptor type 110.137
Sox2SRY-box containing gene 20.135
En2engrailed 20.127
CrebbpCREB binding protein0.109
Cbfa2t3core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)0.098
Nf1neurofibromatosis 10.098
Gata4GATA binding protein 40.077
Notch2Notch gene homolog 2 (Drosophila)0.077
Lmx1bLIM homeobox transcription factor 1 beta0.070
Gli2GLI-Kruppel family member GLI20.069
Meox2mesenchyme homeobox 20.069
Trp53transformation related protein 530.068
Efnb2ephrin B20.067
Hoxa1homeobox A10.067
Gbx2gastrulation brain homeobox 20.066
Arid1aAT rich interactive domain 1A (SWI-like)0.066
Dll1delta-like 1 (Drosophila)0.064
Hand2heart and neural crest derivatives expressed transcript 20.060
Rxraretinoid X receptor alpha0.059
Hspg2perlecan (heparan sulfate proteoglycan 2)0.058
Lama5laminin, alpha 50.057
Phox2apaired-like homeobox 2a0.057
Tcf15transcription factor 150.056
Raf1v-raf-leukemia viral oncogene 10.055
Nkx2-2NK2 transcription factor related, locus 2 (Drosophila)0.054
Smad4MAD homolog 4 (Drosophila)0.053
Olig2oligodendrocyte transcription factor 20.052
Id2inhibitor of DNA binding 20.051
Sox17SRY-box containing gene 170.048
Alx4aristaless-like homeobox 40.047
Id1inhibitor of DNA binding 10.046
Sox3SRY-box containing gene 30.042
Fgfr1fibroblast growth factor receptor 10.042
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.041
Tcfap2atranscription factor AP-2, alpha0.041
Insm1insulinoma-associated 10.041
Psen1presenilin 10.039
Id3inhibitor of DNA binding 30.037
Btbd17BTB (POZ) domain containing 170.037
Ascl1achaete-scute complex homolog 1 (Drosophila)0.035
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.034
Bmp4bone morphogenetic protein 40.032
Zfp423zinc finger protein 4230.031
Shesrc homology 2 domain-containing transforming protein E0.030
Ntf5neurotrophin 50.030
Pkd1polycystic kidney disease 1 homolog0.029
Dll4delta-like 4 (Drosophila)0.029
Sox18SRY-box containing gene 180.028
Ptf1apancreas specific transcription factor, 1a0.027
Fgf10fibroblast growth factor 100.026
Sox11SRY-box containing gene 110.025
Col1a1collagen, type I, alpha 10.025
Hrhairless0.025
En1engrailed 10.025
Fgf17fibroblast growth factor 170.024
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.024
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.022
Nkx2-3NK2 transcription factor related, locus 3 (Drosophila)0.022
Bcl6bB-cell CLL/lymphoma 6, member B0.022
Nos3nitric oxide synthase 3, endothelial cell0.021
Tbrachyury0.021
Trraptransformation/transcription domain-associated protein0.020
Smosmoothened homolog (Drosophila)0.020
Dstdystonin0.020
Chd4chromodomain helicase DNA binding protein 40.020
Neurod4neurogenic differentiation 40.020
Tcfap2ctranscription factor AP-2, gamma0.020
Egfl7EGF-like domain 70.019
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism