The network for 'modification dependent protein catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

modification dependent protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein.

NameDescriptionProbabilityFunc Analog Organism
Prosbeta2Proteasome beta2 subunit0.982
CycBCyclin B0.889
tefutelomere fusion0.840
Rpt1CG1341 gene product from transcript CG1341-RA0.818
Mov34CG3416 gene product from transcript CG3416-RA0.781
Pros29Proteasome 29kD subunit0.780
Rpn9CG10230 gene product from transcript CG10230-RB0.769
Rpt4CG3455 gene product from transcript CG3455-RA0.769
skpACG16983 gene product from transcript CG16983-RD0.685
Prosbeta1Proteasome beta1 subunit0.655
Pros54Proteasome 54kD subunit0.650
CG13349CG13349 gene product from transcript CG13349-RA0.623
Ras85DRas oncogene at 85D0.608
Prosalpha5Proteasome alpha5 subunit0.597
Pros26.4Proteasome 26S subunit subunit 4 ATPase0.586
Rpn7CG5378 gene product from transcript CG5378-RA0.571
Prosbeta3Proteasome beta3 subunit0.568
Rpt3CG16916 gene product from transcript CG16916-RA0.542
Tbp-1Tat-binding protein-10.541
dcodiscs overgrown0.504
poloCG12306 gene product from transcript CG12306-RA0.494
Rpn3Regulatory particle non-ATPase 30.472
Rpn1CG7762 gene product from transcript CG7762-RA0.463
ncdnon-claret disjunctional0.462
Fcp1CG12252 gene product from transcript CG12252-RA0.443
CG12321CG12321 gene product from transcript CG12321-RA0.418
Rpn12CG4157 gene product from transcript CG4157-RA0.413
Rpn11CG18174 gene product from transcript CG18174-RA0.398
Pros28.1Proteasome 28kD subunit 10.397
Tak1TGF-beta activated kinase 10.395
Cap-GCG34438 gene product from transcript CG34438-RF0.392
Rpn2CG11888 gene product from transcript CG11888-RA0.385
Rpn5CG1100 gene product from transcript CG1100-RA0.377
brmbrahma0.374
lqfliquid facets0.367
Pros26Proteasome 26kD subunit0.354
krzkurtz0.349
UbcD2Ubiquitin conjugating enzyme 20.348
Pros45CG1489 gene product from transcript CG1489-RA0.346
lsnlarsen0.334
lin19lin-19-like0.317
Rpn6Proteasome p44.5 subunit0.307
nejnejire0.306
CG4673CG4673 gene product from transcript CG4673-RB0.302
Rab1Rab-protein 10.300
Vps25Vacuolar protein sorting 250.291
DrefDNA replication-related element factor0.291
p53CG33336 gene product from transcript CG33336-RB0.272
Cul-3Cullin-30.272
RelRelish0.266
Tip60CG6121 gene product from transcript CG6121-RA0.257
fzyfizzy0.254
CG9135CG9135 gene product from transcript CG9135-RB0.250
Vap-33-1CG5014 gene product from transcript CG5014-RB0.244
cal1chromosome alignment defect 10.234
DoaDarkener of apricot0.216
endosendosulfine0.209
wdbwiderborst0.203
slmbsupernumerary limbs0.198
Aos1CG12276 gene product from transcript CG12276-RA0.195
CycGCyclin G0.187
Spc105RSpc105-related0.180
barrbarren0.178
Top1Topoisomerase 10.165
CycB3Cyclin B30.164
Akt1CG4006 gene product from transcript CG4006-RA0.162
ttvtout-velu0.159
stepsteppke0.157
Prosbeta7Proteasome beta7 subunit0.147
gwlgreatwall0.146
Su(var)2-10Suppressor of variegation 2-100.146
dshdishevelled0.145
kiskismet0.144
belbelle0.144
CSN1bCOP9 complex homolog subunit 1 b0.140
CG4603CG4603 gene product from transcript CG4603-RA0.138
rapretina aberrant in pattern0.137
Hsp83Heat shock protein 830.135
Uba1Ubiquitin activating enzyme 10.132
gemininCG3183 gene product from transcript CG3183-RA0.131
CG2247CG2247 gene product from transcript CG2247-RA0.129
jubAjuba LIM protein0.129
CG17331CG17331 gene product from transcript CG17331-RA0.125
dpdumpy0.125
CG11247CG11247 gene product from transcript CG11247-RC0.123
CG13625CG13625 gene product from transcript CG13625-RA0.123
smosmoothened0.122
dhddeadhead0.116
CspCysteine string protein0.116
CG9772CG9772 gene product from transcript CG9772-RB0.115
cpacapping protein alpha0.115
UbcD10Ubiquitin conjugating enzyme 100.115
p47CG11139 gene product from transcript CG11139-RA0.114
agoarchipelago0.113
matsmob as tumor suppressor0.111
CG9705CG9705 gene product from transcript CG9705-RA0.110
CG5555CG5555 gene product from transcript CG5555-RA0.110
Prosbeta5Proteasome beta5 subunit0.110
flflfalafel0.108
jarjaguar0.107
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
rpn-7Protein RPN-70.914
rpn-12Protein RPN-120.905
rpt-3Protein RPT-30.697
pas-4Protein PAS-40.692
rpt-2Protein RPT-20.652
pbs-2Protein PBS-20.589
pas-2Protein PAS-20.568
cul-1Protein CUL-10.484
pas-6Protein PAS-60.473
pbs-6Protein PBS-60.457
rpn-2Protein RPN-20.450
rpn-3Protein RPN-30.415
imb-2Protein IMB-20.403
pbs-7Protein PBS-70.358
rpt-5Protein RPT-50.353
pbs-4Protein PBS-40.346
pbs-3Protein PBS-30.321
npl-4.2Protein NPL-4.20.312
rpn-9Protein RPN-90.290
rnr-1Protein RNR-10.283
app-1Protein APP-10.276
rod-1Protein ROD-10.272
tba-2Protein TBA-20.262
par-5Protein PAR-50.248
pbs-1Protein PBS-10.237
egl-18Protein EGL-180.232
pas-1Protein PAS-10.227
rpt-4Protein RPT-40.202
rfc-2Protein RFC-20.193
pbs-5Protein PBS-50.186
mig-5Protein MIG-50.179
ima-2Protein IMA-20.170
taf-5Protein TAF-50.154
rpn-10Protein RPN-100.153
mdf-2Protein MDF-20.140
daf-21Protein DAF-210.129
usp-14Protein USP-140.125
rpn-5Protein RPN-50.109
rpt-6Protein RPT-60.109
bub-1Protein BUB-10.108
pas-5Protein PAS-50.107
ubc-25Protein UBC-250.107
zen-4Protein ZEN-40.104
E04D5.1Protein E04D5.10.103
npl-4.1Protein NPL-4.10.102
skr-1Protein SKR-10.097
pcn-1Protein PCN-10.096
pas-7Protein PAS-70.096
F29G9.2Protein F29G9.20.094
hsr-9Protein HSR-90.093
stam-1Protein STAM-10.088
dlc-1Protein DLC-10.086
rpa-1Protein RPA-10.086
trap-4Protein TRAP-40.086
psr-1Protein PSR-10.082
CELE_Y106G6H.6Protein Y106G6H.60.082
rad-26Protein RAD-260.078
pri-2Protein PRI-20.077
pup-2Protein PUP-20.075
CELE_C25A1.4Protein C25A1.40.075
pas-3Protein PAS-30.073
atx-3Protein ATX-30.070
ubr-1Protein UBR-10.063
pkc-3Protein PKC-30.062
atg-13Protein ATG-130.062
npp-22Protein NPP-220.062
rpn-11Protein RPN-110.061
ran-1Protein RAN-10.060
T22F3.2Protein T22F3.20.059
csn-3Protein CSN-30.059
CELE_C24H12.5Protein C24H12.50.059
klp-16Protein KLP-160.058
htz-1Protein HTZ-10.058
CELE_T10C6.6Protein T10C6.60.057
K08E3.5Protein K08E3.50.056
ZK507.6Protein ZK507.60.056
hgrs-1Protein HGRS-10.055
imp-2Protein IMP-20.055
asb-1Protein ASB-10.054
ubq-1Protein UBQ-10.053
snr-2Protein SNR-20.053
syx-17Protein SYX-170.052
emo-1Protein EMO-10.052
gei-11Protein GEI-110.051
rpt-1Protein RPT-10.051
F25B3.6Protein F25B3.60.049
bli-1Protein BLI-10.049
Y47D3A.29Protein Y47D3A.290.049
trap-3Protein TRAP-30.048
xbp-1Protein XBP-10.048
syx-5Protein SYX-50.048
cec-10Protein CEC-100.047
his-42Protein HIS-420.047
CELE_R102.5Protein R102.50.047
F36D4.5Protein F36D4.50.046
mcm-6Protein MCM-60.046
ucr-2.3Protein UCR-2.30.046
mdf-1Protein MDF-10.045
R07G3.7Protein R07G3.70.045
W08E12.7Protein W08E12.70.044
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
psmb1proteasome (prosome, macropain) subunit, beta type, 10.965
psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.963
psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.927
psma8proteasome (prosome, macropain) subunit, alpha type, 80.892
psmb7proteasome (prosome, macropain) subunit, beta type, 70.856
psma6aproteasome (prosome, macropain) subunit, alpha type, 6a0.850
psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.845
psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.783
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.749
hspa5heat shock protein 50.743
psmb3proteasome (prosome, macropain) subunit, beta type, 30.739
psmb2proteasome (prosome, macropain) subunit, beta type, 20.728
vcpvalosin containing protein0.723
psmb4proteasome (prosome, macropain) subunit, beta type, 40.699
psmd4bproteasome (prosome, macropain) 26S subunit, non-ATPase, 4b0.679
wnt4awingless-type MMTV integration site family, member 4a0.676
zgc:92775zgc:927750.631
dynlrb1dynein, light chain, roadblock-type 10.620
hyou1hypoxia up-regulated 10.614
cdc20cell division cycle 20 homolog0.601
psmc1bproteasome (prosome, macropain) 26S subunit, ATPase, 1b0.592
dlgap5discs, large (Drosophila) homolog-associated protein 50.582
maxmyc-associated factor X0.559
psmb5proteasome (prosome, macropain) subunit, beta type, 50.550
ccnb1cyclin B10.520
psmc3proteasome (prosome, macropain) 26S subunit, ATPase, 30.510
psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.501
zgc:55671zgc:556710.494
ck2bcasein kinase 2 beta0.493
zgc:86903zgc:869030.473
ccnecyclin E0.472
naspnuclear autoantigenic sperm protein (histone-binding)0.462
si:ch73-60e21.1si:ch73-60e21.10.459
psma2proteasome (prosome, macropain) subunit, alpha type, 20.441
ccnb2cyclin B20.431
psma5proteasome (prosome, macropain) subunit, alpha type,50.427
chukconserved helix-loop-helix ubiquitous kinase0.426
capn2bcalpain 2, (m/II) large subunit b0.424
psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.420
baxabcl2-associated X protein, a0.419
hspa8heat shock protein 80.418
orc1origin recognition complex, subunit 10.403
psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.398
rbpjarecombination signal binding protein for immunoglobulin kappa J region a0.393
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.385
plk1polo-like kinase 1 (Drosophila)0.372
chmp4bchromatin modifying protein 4B0.363
zgc:56200zgc:562000.362
ube2d1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.356
syvn1synovial apoptosis inhibitor 1, synoviolin0.338
ccna2cyclin A20.333
ywhabatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a0.329
eif1beukaryotic translation initiation factor 1B0.323
axin1axin 10.322
ihhaIndian hedgehog homolog a0.322
eif1axbeukaryotic translation initiation factor 1A, X-linked, b0.319
gmnngeminin, DNA replication inhibitor0.318
lancl1LanC antibiotic synthetase component C-like 1 (bacterial)0.317
aurkbaurora kinase B0.314
zgc:111944zgc:1119440.314
ube2g2ubiquitin-conjugating enzyme E2G 20.311
kif23kinesin family member 230.303
tia1lcytotoxic granule-associated RNA binding protein 1, like0.301
smek1SMEK homolog 1, suppressor of mek1 (Dictyostelium)0.300
bsdc1BSD domain containing 10.299
dnajc3DnaJ (Hsp40) homolog, subfamily C, member 30.297
psma1proteasome (prosome, macropain) subunit, alpha type, 10.294
fbxw2F-box and WD repeat domain containing 20.292
zgc:55448zgc:554480.287
cct5chaperonin containing TCP1, subunit 5 (epsilon)0.282
tmed2transmembrane emp24 domain trafficking protein 20.281
csnk1dbcasein kinase 1, delta b0.278
si:ch211-244o22.2si:ch211-244o22.20.278
zgc:153910zgc:1539100.276
psmd11aproteasome (prosome, macropain) 216S subunit, non-ATPase, 11a0.274
sec23aSec23 homolog A (S. cerevisiae)0.272
smndc1survival motor neuron domain containing 10.272
zgc:110116zgc:1101160.270
nexnnexilin (F actin binding protein)0.267
tlk2tousled-like kinase 20.267
bc2putative breast adenocarcinoma marker0.266
zgc:77817zgc:778170.264
gps1G protein pathway suppressor 10.263
si:ch211-69g19.2si:ch211-69g19.20.261
ciapin1cytokine induced apoptosis inhibitor 10.260
usp5ubiquitin specific protease 50.258
kpna2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.255
hsbp1heat shock factor binding protein 10.254
mapkapk2amitogen-activated protein kinase-activated protein kinase 2a0.252
cdt1chromatin licensing and DNA replication factor 10.250
hspa4bheat shock protein 4b0.249
rqcd1RCD1 required for cell differentiation1 homolog (S. pombe)0.248
pxnpaxillin0.246
akt2v-akt murine thymoma viral oncogene homolog 20.246
tceb1btranscription elongation factor B (SIII), polypeptide 1b0.244
zgc:110113zgc:1101130.241
abcf1ATP-binding cassette, sub-family F (GCN20), member 10.240
atxn2lataxin 2-like0.238
rlfrearranged L-myc fusion0.237
zgc:123326zgc:1233260.232
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
UBCubiquitin C1.000
VCPvalosin containing protein1.000
RNF11ring finger protein 111.000
XIAPX-linked inhibitor of apoptosis1.000
TP53tumor protein p531.000
CUL3cullin 31.000
UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)1.000
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 41.000
UBE2V1ubiquitin-conjugating enzyme E2 variant 11.000
UBE2D2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)1.000
PTK2PTK2 protein tyrosine kinase 20.999
CDC27cell division cycle 27 homolog (S. cerevisiae)0.999
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.999
MDM2Mdm2 p53 binding protein homolog (mouse)0.999
UBE2D1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.999
PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.998
UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)0.998
PSMA1proteasome (prosome, macropain) subunit, alpha type, 10.998
SKP2S-phase kinase-associated protein 2 (p45)0.998
RBX1ring-box 1, E3 ubiquitin protein ligase0.998
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.997
SKP1S-phase kinase-associated protein 10.997
PSMA7proteasome (prosome, macropain) subunit, alpha type, 70.997
CDC20cell division cycle 20 homolog (S. cerevisiae)0.995
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.995
RB1retinoblastoma 10.995
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.995
PSMB7proteasome (prosome, macropain) subunit, beta type, 70.995
PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 60.994
PSMD13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.994
STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase0.994
PSME3proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)0.993
UBQLN1ubiquilin 10.993
TRIM39tripartite motif containing 390.993
PSMA2proteasome (prosome, macropain) subunit, alpha type, 20.992
HSPA8heat shock 70kDa protein 80.991
CUL1cullin 10.991
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.991
HDAC1histone deacetylase 10.990
PSMB1proteasome (prosome, macropain) subunit, beta type, 10.989
BIRC2baculoviral IAP repeat containing 20.989
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.988
UBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog)0.987
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.987
MAP3K7mitogen-activated protein kinase kinase kinase 70.986
PSMB2proteasome (prosome, macropain) subunit, beta type, 20.984
BTRCbeta-transducin repeat containing0.982
OTUB1OTU domain, ubiquitin aldehyde binding 10.982
RNF111ring finger protein 1110.982
PSMA6proteasome (prosome, macropain) subunit, alpha type, 60.981
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.981
CDK2cyclin-dependent kinase 20.980
SMURF2SMAD specific E3 ubiquitin protein ligase 20.978
PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.976
ATXN3ataxin 30.973
PSMC4proteasome (prosome, macropain) 26S subunit, ATPase, 40.971
PSMA3proteasome (prosome, macropain) subunit, alpha type, 30.970
PLK1polo-like kinase 10.968
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.965
PSMA4proteasome (prosome, macropain) subunit, alpha type, 40.963
UBE3Aubiquitin protein ligase E3A0.962
PSMB3proteasome (prosome, macropain) subunit, beta type, 30.960
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.959
RAD23BRAD23 homolog B (S. cerevisiae)0.959
TCEB1transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)0.958
ANAPC4anaphase promoting complex subunit 40.958
SYVN1synovial apoptosis inhibitor 1, synoviolin0.957
ADRM1adhesion regulating molecule 10.954
ARIH2ariadne homolog 2 (Drosophila)0.953
UHRF2ubiquitin-like with PHD and ring finger domains 20.951
PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 30.949
FBXW11F-box and WD repeat domain containing 110.947
CCNB1cyclin B10.944
SMAD2SMAD family member 20.943
TRAF6TNF receptor-associated factor 60.942
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.940
PSMB4proteasome (prosome, macropain) subunit, beta type, 40.939
PSMD12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.939
PDCD6IPprogrammed cell death 6 interacting protein0.938
ZNRF1zinc and ring finger 10.935
ANAPC11anaphase promoting complex subunit 110.932
PSMB6proteasome (prosome, macropain) subunit, beta type, 60.929
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma0.922
CSNK1Ecasein kinase 1, epsilon0.921
UBE2L6ubiquitin-conjugating enzyme E2L 60.920
UFD1Lubiquitin fusion degradation 1 like (yeast)0.917
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.916
HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)0.915
TRIM43tripartite motif containing 430.914
POMPproteasome maturation protein0.912
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.910
SMAD4SMAD family member 40.909
PSMB5proteasome (prosome, macropain) subunit, beta type, 50.908
PSMA5proteasome (prosome, macropain) subunit, alpha type, 50.906
RNF126ring finger protein 1260.904
CCNA2cyclin A20.903
BCAR1breast cancer anti-estrogen resistance 10.900
MDM4Mdm4 p53 binding protein homolog (mouse)0.899
ANAPC7anaphase promoting complex subunit 70.898
PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 20.896
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.999
Ctnnb1catenin (cadherin associated protein), beta 10.997
Mdm2transformed mouse 3T3 cell double minute 20.996
Axin1axin 10.989
Psma7proteasome (prosome, macropain) subunit, alpha type 70.985
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.985
Per2period homolog 2 (Drosophila)0.982
Psen1presenilin 10.982
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.975
Psma2proteasome (prosome, macropain) subunit, alpha type 20.959
Psmb6proteasome (prosome, macropain) subunit, beta type 60.958
Nedd4neural precursor cell expressed, developmentally down-regulated 40.949
Akt1thymoma viral proto-oncogene 10.942
Arntlaryl hydrocarbon receptor nuclear translocator-like0.931
Cdk1cyclin-dependent kinase 10.926
Ccnb1cyclin B10.925
Gsk3bglycogen synthase kinase 3 beta0.925
Psma3proteasome (prosome, macropain) subunit, alpha type 30.924
Psma5proteasome (prosome, macropain) subunit, alpha type 50.920
Psma6proteasome (prosome, macropain) subunit, alpha type 60.913
Psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.908
Ncstnnicastrin0.901
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.896
Per1period homolog 1 (Drosophila)0.887
Psma1proteasome (prosome, macropain) subunit, alpha type 10.887
Psmb7proteasome (prosome, macropain) subunit, beta type 70.880
Ncoa3nuclear receptor coactivator 30.852
Ptenphosphatase and tensin homolog0.851
Apcadenomatosis polyposis coli0.850
Cry2cryptochrome 2 (photolyase-like)0.845
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.844
Clockcircadian locomotor output cycles kaput0.840
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.840
Rrm2ribonucleotide reductase M20.824
Vcpvalosin containing protein0.815
Usp9xubiquitin specific peptidase 9, X chromosome0.770
Psmb4proteasome (prosome, macropain) subunit, beta type 40.763
Gnb2guanine nucleotide binding protein (G protein), beta 20.755
Csnk1ecasein kinase 1, epsilon0.745
Rnf19aring finger protein 19A0.739
SkilSKI-like0.733
Psmd14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.731
Mdm4transformed mouse 3T3 cell double minute 40.719
Rnf111ring finger 1110.714
Birc5baculoviral IAP repeat-containing 50.710
Cops5COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)0.709
Fgfr1fibroblast growth factor receptor 10.704
Appamyloid beta (A4) precursor protein0.696
Tax1bp1Tax1 (human T-cell leukemia virus type I) binding protein 10.690
Anapc2anaphase promoting complex subunit 20.684
Ldb3LIM domain binding 30.667
Hif1ahypoxia inducible factor 1, alpha subunit0.661
Cul4acullin 4A0.654
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.654
Dctn1dynactin 10.633
Ranbp9RAN binding protein 90.632
Add1adducin 1 (alpha)0.620
Kif22kinesin family member 220.619
Hspa5heat shock protein 50.612
Ccne1cyclin E10.584
Cry1cryptochrome 1 (photolyase-like)0.584
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.582
Arrb2arrestin, beta 20.572
Pompproteasome maturation protein0.563
Smurf2SMAD specific E3 ubiquitin protein ligase 20.554
Tab3TGF-beta activated kinase 1/MAP3K7 binding protein 30.553
Csnk1g2casein kinase 1, gamma 20.547
Ubxn1UBX domain protein 10.533
Mlf2myeloid leukemia factor 20.529
Aampangio-associated migratory protein0.527
Arrb1arrestin, beta 10.522
Skp1aS-phase kinase-associated protein 1A0.517
Mgea5meningioma expressed antigen 5 (hyaluronidase)0.501
Prc1protein regulator of cytokinesis 10.498
Chek1checkpoint kinase 1 homolog (S. pombe)0.496
Carm1coactivator-associated arginine methyltransferase 10.495
Adrm1adhesion regulating molecule 10.491
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.487
Bap1Brca1 associated protein 10.487
Cyldcylindromatosis (turban tumor syndrome)0.485
Tbx3T-box 30.483
Lemd2LEM domain containing 20.480
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.477
Pcnaproliferating cell nuclear antigen0.476
Ccnb2cyclin B20.474
Rnf2ring finger protein 20.469
Dvl1dishevelled, dsh homolog 1 (Drosophila)0.463
Psma4proteasome (prosome, macropain) subunit, alpha type 40.458
Kif20akinesin family member 20A0.453
Dab1disabled homolog 1 (Drosophila)0.448
Prkceprotein kinase C, epsilon0.445
Ccna2cyclin A20.443
Dyrk1adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a0.440
Skiski sarcoma viral oncogene homolog (avian)0.433
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.432
Smad7MAD homolog 7 (Drosophila)0.424
Vhlvon Hippel-Lindau tumor suppressor0.422
Psme4proteasome (prosome, macropain) activator subunit 40.419
Ctnnd1catenin (cadherin associated protein), delta 10.419
Crb2crumbs homolog 2 (Drosophila)0.407
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Psma3proteasome (prosome, macropain) subunit, alpha type 30.993
Psma5proteasome (prosome, macropain) subunit, alpha type 50.974
Psma4proteasome (prosome, macropain) subunit, alpha type 40.928
Psmb3proteasome (prosome, macropain) subunit, beta type 30.925
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.725
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.724
Psma7proteasome (prosome, macropain) subunit, alpha type 70.604
CnbpCCHC-type zinc finger, nucleic acid binding protein0.509
Psme2proteasome (prosome, macropain) activator subunit 20.375
Psmb7proteasome (prosome, macropain) subunit, beta type 70.373
Psmb2proteasome (prosome, macropain) subunit, beta type 20.311
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.308
Psmb6proteasome (prosome, macropain) subunit, beta type 60.222
Psma2proteasome (prosome, macropain) subunit, alpha type 20.216
Psmd14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.202
Acyp2acylphosphatase 2, muscle type0.174
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.171
Psmb8proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)0.166
Psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.159
Mapre1microtubule-associated protein, RP/EB family, member 10.156
Dnajb11DnaJ (Hsp40) homolog, subfamily B, member 110.145
Ptges3prostaglandin E synthase 3 (cytosolic)0.131
Psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.124
Zfand5zinc finger, AN1-type domain 50.113
Psmb10proteasome (prosome, macropain) subunit, beta type 100.107
Psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.106
Ube2d2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)0.100
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.099
Hsp90b1heat shock protein 90, beta, member 10.094
Eef2eukaryotic translation elongation factor 20.087
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.086
Pompproteasome maturation protein0.082
Pdia4protein disulfide isomerase family A, member 40.081
Creld2cysteine-rich with EGF-like domains 20.081
Manfmesencephalic astrocyte-derived neurotrophic factor0.080
Csnk1dcasein kinase 1, delta0.077
Psmb5proteasome (prosome, macropain) subunit, beta type 50.072
Txnl1thioredoxin-like 10.071
Nsfl1cNSFL1 (p97) cofactor (p47)0.070
Psmd1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.064
Psma1proteasome (prosome, macropain) subunit, alpha type 10.063
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.060
Cdk4cyclin-dependent kinase 40.057
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.056
Phaxphosphorylated adaptor for RNA export0.056
Jtbjumping translocation breakpoint0.054
Dnajc3DnaJ (Hsp40) homolog, subfamily C, member 30.053
Hspa5heat shock protein 50.053
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.051
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.049
LOC100366237prefoldin subunit 4-like0.048
Psmd7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.046
Taok1TAO kinase 10.045
Rab5aRAB5A, member RAS oncogene family0.042
Dusp11dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)0.041
Pfn1profilin 10.040
Txnrd1thioredoxin reductase 10.039
Clic4chloride intracellular channel 40.038
Ppm1aprotein phosphatase 1A, magnesium dependent, alpha isoform0.037
Dnajb9DnaJ (Hsp40) homolog, subfamily B, member 90.037
Ube2bubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae)0.037
Dnajc5DnaJ (Hsp40) homolog, subfamily C, member 50.036
Foxm1forkhead box M10.034
Karslysyl-tRNA synthetase0.033
Calrcalreticulin0.033
Tolliptoll interacting protein0.030
Dctn4dynactin 40.030
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.030
Ppp1r2protein phosphatase 1, regulatory (inhibitor) subunit 20.029
Pdia3protein disulfide isomerase family A, member 30.029
Ccnb1cyclin B10.029
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.028
Spcs2signal peptidase complex subunit 2 homolog (S. cerevisiae)0.028
TiprlTIP41, TOR signaling pathway regulator-like (S. cerevisiae)0.027
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.027
Rab11aRAB11a, member RAS oncogene family0.026
Sumo1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.026
Golph3golgi phosphoprotein 3 (coat-protein)0.026
Serinc1serine incorporator 10.025
Cand1cullin-associated and neddylation-dissociated 10.024
March5membrane-associated ring finger (C3HC4) 50.024
Mgat2mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase0.024
Azi25-azacytidine induced 20.024
Psmd5proteasome (prosome, macropain) 26S subunit, non-ATPase, 50.023
RGD1309102similar to TRS85 homolog0.023
Sec61a1Sec61 alpha 1 subunit (S. cerevisiae)0.023
Ube2iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.023
Ubcubiquitin C0.023
Pex13peroxisomal biogenesis factor 130.023
Rgs19regulator of G-protein signaling 190.023
Psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.021
Hprt1hypoxanthine phosphoribosyltransferase 10.021
Ppm1bprotein phosphatase 1B, magnesium dependent, beta isoform0.021
Ifi27l2binterferon, alpha-inducible protein 27 like 2B0.020
Zfp364zinc finger protein 3640.020
Pdia6protein disulfide isomerase family A, member 60.020
Top2atopoisomerase (DNA) II alpha0.019
Psmb1proteasome (prosome, macropain) subunit, beta type 10.019
Nploc4nuclear protein localization 4 homolog (S. cerevisiae)0.019
Cops5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.019
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
CDC48Cdc48p1.000
RPT1Rpt1p0.999
RPT6Rpt6p0.995
PRE1Pre1p0.994
RAD23Rad23p0.992
RPT4Rpt4p0.991
RPN10Rpn10p0.989
RPN11Rpn11p0.980
KAR2Kar2p0.979
PRE10Pre10p0.967
RPT3Rpt3p0.959
SKP1Skp1p0.958
RPT2Rpt2p0.956
UFD4Ufd4p0.951
MAD2Mad2p0.948
FYV10Fyv10p0.944
HRD1Hrd1p0.943
MND2Mnd2p0.940
APC5Apc5p0.940
PPH21Pph21p0.939
RPT5Rpt5p0.938
RPN12Rpn12p0.928
RPN6Rpn6p0.920
PPH22Pph22p0.915
UFD2Ufd2p0.915
CDC23Cdc23p0.908
PRE2Pre2p0.905
PRE4Pre4p0.888
CDC53Cdc53p0.881
PRE5Pre5p0.870
ECM29Ecm29p0.866
DOC1Doc1p0.859
MUB1Mub1p0.853
HRT1Hrt1p0.838
VPS27Vps27p0.836
CDC16Cdc16p0.833
SCJ1Scj1p0.832
PMT1Pmt1p0.821
HRD3Hrd3p0.812
VID30Vid30p0.811
PRE9Pre9p0.809
PUP2Pup2p0.807
UMP1Ump1p0.801
PUP3Pup3p0.794
RPN3Rpn3p0.789
UBR1Ubr1p0.788
DSK2Dsk2p0.788
OTU1Otu1p0.783
PUP1Pup1p0.778
CDC20Cdc20p0.773
PRE7Pre7p0.772
SCL1Scl1p0.761
RPN7Rpn7p0.760
CDC26Cdc26p0.756
NOP6Nop6p0.755
UFD1Ufd1p0.755
UBP6Ubp6p0.753
PRE6Pre6p0.752
ELC1Elc1p0.748
NPL4Npl4p0.739
SWM1Swm1p0.737
APC2Apc2p0.729
VID28Vid28p0.725
CDC4Cdc4p0.706
VPS36Vps36p0.704
RPN9Rpn9p0.700
MET30Met30p0.694
RPN4Rpn4p0.694
CDC27Cdc27p0.683
GPB2Gpb2p0.681
RPN8Rpn8p0.668
DER1Der1p0.663
BRE5Bre5p0.650
DFM1Dfm1p0.619
APC1Apc1p0.614
UBC4Ubc4p0.595
RPN1Rpn1p0.589
CDC34Cdc34p0.576
APC9Apc9p0.575
CDC31Cdc31p0.566
BUB3Bub3p0.563
GPR1Gpr1p0.562
CTF13Ctf13p0.548
UBX3Ubx3p0.545
SGT2Sgt2p0.544
VPS60Vps60p0.541
RPN13Rpn13p0.529
CSE4Cse4p0.526
MCM21Mcm21p0.525
PRE3Pre3p0.517
RPN2Rpn2p0.503
YLR352Whypothetical protein0.486
YMR258Chypothetical protein0.485
DDI1Ddi1p0.482
BLM10Blm10p0.456
YDJ1Ydj1p0.443
RAD6Rad6p0.442
PRE8Pre8p0.439
RKR1Rkr1p0.424
VID24Vid24p0.422