The network for 'organic hydroxy compound catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

organic hydroxy compound catabolic process

The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound.

NameDescriptionProbabilityFunc Analog Organism
CG1927CG1927 gene product from transcript CG1927-RA0.030
CG12171CG12171 gene product from transcript CG12171-RA0.028
CG9510CG9510 gene product from transcript CG9510-RC0.022
CG1907CG1907 gene product from transcript CG1907-RA0.021
CG15754CG15754 gene product from transcript CG15754-RA0.020
CG4752CG4752 gene product from transcript CG4752-RA0.020
CG5254CG5254 gene product from transcript CG5254-RA0.020
Hr51Hormone receptor 510.020
GstE6Glutathione S transferase E60.019
CG10863CG10863 gene product from transcript CG10863-RA0.018
glob1globin 10.017
PgmPhosphogluconate mutase0.017
Lsp1betaLarval serum protein 1 beta0.016
CanA-14FCalcineurin A at 14F0.016
CG5397CG5397 gene product from transcript CG5397-RA0.016
CG7272CG7272 gene product from transcript CG7272-RA0.016
Est-6Esterase 60.016
CG31743CG31743 gene product from transcript CG31743-RA0.015
CG17026CG17026 gene product from transcript CG17026-RA0.015
CG4691CG4691 gene product from transcript CG4691-RA0.015
Ser7CG2045 gene product from transcript CG2045-RA0.014
aralar1CG2139 gene product from transcript CG2139-RC0.014
CG5362CG5362 gene product from transcript CG5362-RA0.014
GpdhGlycerol 3 phosphate dehydrogenase0.014
CG9629CG9629 gene product from transcript CG9629-RA0.014
CG9396CG9396 gene product from transcript CG9396-RA0.014
CG7997CG7997 gene product from transcript CG7997-RB0.014
DopRDopamine receptor0.014
CG17027CG17027 gene product from transcript CG17027-RA0.014
Cyp12d1-pCG30489 gene product from transcript CG30489-RA0.014
JheJuvenile hormone esterase0.014
CG9894CG9894 gene product from transcript CG9894-RB0.014
yip2yippee interacting protein 20.013
Cyp4d2Cytochrome P450-4d20.013
ImpL3Ecdysone-inducible gene L30.013
proPO-A1prophenol oxidase A10.013
CG14815CG14815 gene product from transcript CG14815-RA0.013
CG14526CG14526 gene product from transcript CG14526-RB0.013
CG10960CG10960 gene product from transcript CG10960-RC0.013
elmethanol sensitive with low memory0.013
CG16799CG16799 gene product from transcript CG16799-RA0.013
CG8790CG8790 gene product from transcript CG8790-RB0.013
Got2Glutamate oxaloacetate transaminase 20.013
Cyp6a23CG10242 gene product from transcript CG10242-RA0.013
Cyp4d21CG6730 gene product from transcript CG6730-RA0.013
Oatp30BOrganic anion transporting polypeptide 30B0.013
altaluminum tubes0.013
GNBP3Gram-negative bacteria binding protein 30.013
CG4928CG4928 gene product from transcript CG4928-RA0.013
Got1Glutamate oxaloacetate transaminase 10.013
GstE7Glutathione S transferase E70.013
BmcpCG7314 gene product from transcript CG7314-RB0.012
PgkPhosphoglycerate kinase0.012
Lsp2Larval serum protein 20.012
CG5707CG5707 gene product from transcript CG5707-RA0.012
CG30427CG30427 gene product from transcript CG30427-RC0.012
Jafrac1thioredoxin peroxidase 10.012
GluRIIAGlutamate receptor IIA0.012
Cyp12c1CG4120 gene product from transcript CG4120-RA0.012
CG9498CG9498 gene product from transcript CG9498-RA0.012
CG10562CG10562 gene product from transcript CG10562-RA0.012
CG15828CG15828 gene product from transcript CG15828-RC0.012
Ahcy89EAdenosylhomocysteinase 89E0.012
CG9360CG9360 gene product from transcript CG9360-RA0.012
EfrER GDP-fucose transporter0.012
CG2254CG2254 gene product from transcript CG2254-RA0.012
Prx2540-2Peroxiredoxin 25400.012
CG17928CG17928 gene product from transcript CG17928-RA0.012
CG16771CG16771 gene product from transcript CG16771-RC0.012
CG9512CG9512 gene product from transcript CG9512-RA0.012
MgstlMicrosomal glutathione S-transferase-like0.012
CG12140CG12140 gene product from transcript CG12140-RA0.012
CG10962CG10962 gene product from transcript CG10962-RB0.012
ird1immune response deficient 10.012
CG10098CG10098 gene product from transcript CG10098-RA0.012
CG13369CG13369 gene product from transcript CG13369-RA0.012
CG10026CG10026 gene product from transcript CG10026-RA0.012
CG5973CG5973 gene product from transcript CG5973-RA0.012
CG17734CG17734 gene product from transcript CG17734-RA0.012
CG4829CG4829 gene product from transcript CG4829-RB0.012
CG5282CG5282 gene product from transcript CG5282-RA0.012
su(r)suppressor of rudimentary0.011
CG13253CG13253 gene product from transcript CG13253-RB0.011
CG15611CG15611 gene product from transcript CG15611-RB0.011
CG32236CG32236 gene product from transcript CG32236-RA0.011
Spn42DcSerpin 42Dc0.011
Ance-4CG8196 gene product from transcript CG8196-RA0.011
CG14741CG14741 gene product from transcript CG14741-RB0.011
Npc2aNiemann-Pick type C-2a0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
ace-2Protein ACE-20.035
ace-3Protein ACE-30.030
C39D10.7Protein C39D10.70.019
ace-1Protein ACE-10.015
nfyb-1Protein NFYB-10.014
perm-4Protein PERM-40.013
ace-4Protein ACE-40.013
F11G11.5Protein F11G11.50.012
CELE_ZK1307.8Protein ZK1307.80.012
perm-5Protein PERM-50.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.909
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.873
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.511
NOXA1NADPH oxidase activator 10.429
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.376
RAB6ARAB6A, member RAS oncogene family0.154
SH3RF1SH3 domain containing ring finger 10.110
HMOX2heme oxygenase (decycling) 20.086
APOEapolipoprotein E0.079
RAB14RAB14, member RAS oncogene family0.064
APOA1apolipoprotein A-I0.063
CYP4F2cytochrome P450, family 4, subfamily F, polypeptide 20.057
APOC1apolipoprotein C-I0.056
PRKCZprotein kinase C, zeta0.054
CDCP1CUB domain containing protein 10.053
CLTCclathrin, heavy chain (Hc)0.052
PRMT2protein arginine methyltransferase 20.041
BRF2BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like0.037
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.036
ARID1BAT rich interactive domain 1B (SWI1-like)0.033
SORBS2sorbin and SH3 domain containing 20.032
NUDT15nudix (nucleoside diphosphate linked moiety X)-type motif 150.031
CYP4F12cytochrome P450, family 4, subfamily F, polypeptide 120.030
PICK1protein interacting with PRKCA 10.028
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.027
PRKCBprotein kinase C, beta0.026
PCSK9proprotein convertase subtilisin/kexin type 90.026
GLTPD1glycolipid transfer protein domain containing 10.026
CYP4F3cytochrome P450, family 4, subfamily F, polypeptide 30.025
NCOA1nuclear receptor coactivator 10.023
APPL1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.022
ZHX1zinc fingers and homeoboxes 10.022
RFKriboflavin kinase0.020
CYP3A43cytochrome P450, family 3, subfamily A, polypeptide 430.020
SH3KBP1SH3-domain kinase binding protein 10.019
SMAD2SMAD family member 20.019
CYP4F11cytochrome P450, family 4, subfamily F, polypeptide 110.019
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.019
MECP2methyl CpG binding protein 2 (Rett syndrome)0.019
CYP2B6cytochrome P450, family 2, subfamily B, polypeptide 60.019
CDC16cell division cycle 16 homolog (S. cerevisiae)0.018
PTK2BPTK2B protein tyrosine kinase 2 beta0.018
LOXL4lysyl oxidase-like 40.018
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.018
KHDRBS1KH domain containing, RNA binding, signal transduction associated 10.017
ARandrogen receptor0.017
FANCCFanconi anemia, complementation group C0.017
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.016
MAPTmicrotubule-associated protein tau0.016
NUMBnumb homolog (Drosophila)0.015
HSPA13heat shock protein 70kDa family, member 130.015
ST13suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)0.015
RAB5ARAB5A, member RAS oncogene family0.015
FABP1fatty acid binding protein 1, liver0.015
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.015
CRYZcrystallin, zeta (quinone reductase)0.014
PLTPphospholipid transfer protein0.014
APOBapolipoprotein B (including Ag(x) antigen)0.014
AKR1C4aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)0.014
MAT1Amethionine adenosyltransferase I, alpha0.014
SLC25A1solute carrier family 25 (mitochondrial carrier; citrate transporter), member 10.013
XPNPEP1X-prolyl aminopeptidase (aminopeptidase P) 1, soluble0.013
CCDC115coiled-coil domain containing 1150.013
KAT2BK(lysine) acetyltransferase 2B0.013
PALLDpalladin, cytoskeletal associated protein0.013
CYP2C8cytochrome P450, family 2, subfamily C, polypeptide 80.013
OTCornithine carbamoyltransferase0.013
ASB13ankyrin repeat and SOCS box containing 130.012
PEX5peroxisomal biogenesis factor 50.012
TALDO1transaldolase 10.012
G6PCglucose-6-phosphatase, catalytic subunit0.012
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.012
BHMTbetaine--homocysteine S-methyltransferase0.012
APOC2apolipoprotein C-II0.012
NMT2N-myristoyltransferase 20.012
CYP2C19cytochrome P450, family 2, subfamily C, polypeptide 190.012
F9coagulation factor IX0.012
BDH23-hydroxybutyrate dehydrogenase, type 20.011
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.011
HALhistidine ammonia-lyase0.011
RDH16retinol dehydrogenase 16 (all-trans)0.011
CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 40.011
CCL14chemokine (C-C motif) ligand 140.011
ZNF71zinc finger protein 710.011
HMGCS23-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)0.011
FOXO3forkhead box O30.011
POFUT1protein O-fucosyltransferase 10.010
FOXO1forkhead box O10.010
C8Acomplement component 8, alpha polypeptide0.010
APOC3apolipoprotein C-III0.010
BADBCL2-associated agonist of cell death0.010
ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 20.010
CHN2chimerin (chimaerin) 20.010
POLR2Kpolymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Apoeapolipoprotein E0.969
Ncoa1nuclear receptor coactivator 10.431
Shc1src homology 2 domain-containing transforming protein C10.412
Trp53transformation related protein 530.344
Nr3c1nuclear receptor subfamily 3, group C, member 10.308
Adh1alcohol dehydrogenase 1 (class I)0.273
Dab1disabled homolog 1 (Drosophila)0.232
Thrbthyroid hormone receptor beta0.226
Ppargperoxisome proliferator activated receptor gamma0.213
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.207
Col1a1collagen, type I, alpha 10.192
Apobapolipoprotein B0.184
Arid1bAT rich interactive domain 1B (SWI-like)0.145
Thrathyroid hormone receptor alpha0.144
Fcgr2bFc receptor, IgG, low affinity IIb0.141
Drd2dopamine receptor D20.138
Ghrgrowth hormone receptor0.127
Hsd3b3hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 30.126
Hsd3b7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 70.118
Smarcc2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.111
Cyp4a14cytochrome P450, family 4, subfamily a, polypeptide 140.110
Myo6myosin VI0.105
Cyp8b1cytochrome P450, family 8, subfamily b, polypeptide 10.104
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.101
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.099
Agtr1aangiotensin II receptor, type 1a0.093
Scd1stearoyl-Coenzyme A desaturase 10.085
Slc12a6solute carrier family 12, member 60.081
Ighimmunoglobulin heavy chain complex0.080
Mapk9mitogen-activated protein kinase 90.080
Unc79unc-79 homolog (C. elegans)0.080
Aldobaldolase B, fructose-bisphosphate0.080
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.079
Kitkit oncogene0.078
Nr1i3nuclear receptor subfamily 1, group I, member 30.070
Adh7alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide0.068
Ctnnb1catenin (cadherin associated protein), beta 10.068
Vav2vav 2 oncogene0.067
Npyneuropeptide Y0.067
Vdrvitamin D receptor0.066
Lrp1low density lipoprotein receptor-related protein 10.059
Npc1Niemann Pick type C10.059
Smarca2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.058
Pick1protein interacting with C kinase 10.058
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.054
F13bcoagulation factor XIII, beta subunit0.053
Thtyrosine hydroxylase0.053
Efemp2epidermal growth factor-containing fibulin-like extracellular matrix protein 20.053
Cyp11b2cytochrome P450, family 11, subfamily b, polypeptide 20.052
Gcgroup specific component0.051
Rbl2retinoblastoma-like 20.050
Hmgcs13-hydroxy-3-methylglutaryl-Coenzyme A synthase 10.047
Hsd3b4hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 40.045
Soat1sterol O-acyltransferase 10.044
Dok1docking protein 10.043
Rb1retinoblastoma 10.042
G6pcglucose-6-phosphatase, catalytic0.042
Fabp4fatty acid binding protein 4, adipocyte0.042
Cyp2c38cytochrome P450, family 2, subfamily c, polypeptide 380.042
Abcc2ATP-binding cassette, sub-family C (CFTR/MRP), member 20.041
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.040
FasFas (TNF receptor superfamily member 6)0.039
Akr1c6aldo-keto reductase family 1, member C60.039
Keg1kidney expressed gene 10.039
Cyp3a13cytochrome P450, family 3, subfamily a, polypeptide 130.038
Tgfbr1transforming growth factor, beta receptor I0.038
Slc22a1solute carrier family 22 (organic cation transporter), member 10.037
Hsd11b1hydroxysteroid 11-beta dehydrogenase 10.036
Fmo1flavin containing monooxygenase 10.036
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.035
Slco1a1solute carrier organic anion transporter family, member 1a10.034
Slc6a13solute carrier family 6 (neurotransmitter transporter, GABA), member 130.034
Cps1carbamoyl-phosphate synthetase 10.033
Cyp7a1cytochrome P450, family 7, subfamily a, polypeptide 10.032
Mioxmyo-inositol oxygenase0.032
BC023829cDNA sequence BC0238290.032
Txnipthioredoxin interacting protein0.032
Apoc4apolipoprotein C-IV0.032
Inmtindolethylamine N-methyltransferase0.031
Atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.031
Abcb7ATP-binding cassette, sub-family B (MDR/TAP), member 70.030
Cav1caveolin 1, caveolae protein0.030
BlnkB-cell linker0.030
Emx1empty spiracles homolog 1 (Drosophila)0.030
Agrpagouti related protein0.030
Aponapolipoprotein N0.029
Rdh16retinol dehydrogenase 160.029
Cyp2d10cytochrome P450, family 2, subfamily d, polypeptide 100.029
Spp2secreted phosphoprotein 20.029
Fam126bfamily with sequence similarity 126, member B0.029
Duox2dual oxidase 20.029
Golt1agolgi transport 1 homolog A (S. cerevisiae)0.029
Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.028
Crtac1cartilage acidic protein 10.028
DaoD-amino acid oxidase0.028
Grb2growth factor receptor bound protein 20.027
Agmatagmatine ureohydrolase (agmatinase)0.027
Flt1FMS-like tyrosine kinase 10.027
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism