The network for 'antimicrobial peptide production' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

antimicrobial peptide production

The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.

NameDescriptionProbabilityFunc Analog Organism
PGRP-LCPeptidoglycan recognition protein LC0.999
SPESpatzle-Processing Enzyme0.951
Spn27ASerpin 27A0.946
PGRP-SDCG7496 gene product from transcript CG7496-RA0.942
ird5immune response deficient 50.923
Sp7Serine protease 70.920
DptBDiptericin B0.909
Spn28DSerpin 28D0.827
ird1immune response deficient 10.791
PGRP-SAPeptidoglycan recognition protein SA0.767
grassGram-positive Specific Serine protease0.759
BG4CG12297 gene product from transcript CG12297-RA0.636
DreddDeath related ced-3/Nedd2-like protein0.619
imdimmune deficiency0.607
Myd88CG2078 gene product from transcript CG2078-RA0.508
Mpk2CG5475 gene product from transcript CG5475-RB0.430
IrcImmune-regulated catalase0.425
AGO2Argonaute 20.395
Spn1Serine protease inhibitor 10.379
CG32185CG32185 gene product from transcript CG32185-RA0.288
PGRP-SC1aCG14746 gene product from transcript CG14746-RA0.228
PvrPDGF- and VEGF-receptor related0.212
pirkpoor Imd response upon knock-in0.199
CG15917CG15917 gene product from transcript CG15917-RA0.193
PGRP-SC1bCG8577 gene product from transcript CG8577-RA0.147
GNBP3Gram-negative bacteria binding protein 30.135
IM18Immune induced molecule 180.122
CG15065CG15065 gene product from transcript CG15065-RA0.119
bowlbrother of odd with entrails limited0.116
Tak1TGF-beta activated kinase 10.111
modSPmodular serine protease0.110
NotumCG13076 gene product from transcript CG13076-RB0.109
Spn88EbSerpin 88Eb0.100
CG7910CG7910 gene product from transcript CG7910-RA0.095
CecCCecropin C0.094
HLHmgammaE(spl) region transcript mgamma0.091
CG18594CG18594 gene product from transcript CG18594-RA0.090
aopanterior open0.089
CG11286CG11286 gene product from transcript CG11286-RA0.083
amosabsent MD neurons and olfactory sensilla0.082
CG8586CG8586 gene product from transcript CG8586-RA0.080
su(Hw)suppressor of Hairy wing0.079
DuoxDual oxidase0.076
NcNedd2-like caspase0.075
cortoCG2530 gene product from transcript CG2530-RA0.073
Tsp42EfTetraspanin 42Ef0.072
Hrb98DEHeterogeneous nuclear ribonucleoprotein at 98DE0.072
p38bCG7393 gene product from transcript CG7393-RA0.072
Traf6TNF-receptor-associated factor 60.070
spiritSerine Protease Immune Response Integrator0.070
eaterCG6124 gene product from transcript CG6124-RB0.069
l(3)mbnlethal (3) malignant blood neoplasm0.069
Mekk1CG7717 gene product from transcript CG7717-RB0.065
CG12766CG12766 gene product from transcript CG12766-RA0.065
CG13641CG13641 gene product from transcript CG13641-RA0.062
PGRP-LBPeptidoglycan recognition protein LB0.062
Gadd45CG11086 gene product from transcript CG11086-RA0.059
RfxCG6312 gene product from transcript CG6312-RA0.059
FhosCG42610 gene product from transcript CG42610-RC0.059
CG42300CG42300 gene product from transcript CG42300-RA0.059
Adgf-AAdenosine deaminase-related growth factor A0.059
CecA2Cecropin A20.057
Tab2TAK1-associated binding protein 20.056
CG16772CG16772 gene product from transcript CG16772-RA0.056
cpbcapping protein beta0.056
PGRP-LFPeptidoglycan recognition protein LF0.053
Cad96CaCG10244 gene product from transcript CG10244-RA0.052
l(3)05822lethal (3) 058220.050
GNBP1Gram-negative bacteria binding protein 10.049
Vps16AVacuolar protein sorting 16A0.049
Gef64CGuanine nucleotide exchange factor GEF64C0.049
JupiterCG31363 gene product from transcript CG31363-RD0.047
TepIIIThiolester containing protein III0.047
Toll-7CG8595 gene product from transcript CG8595-RA0.047
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Tlr4toll-like receptor 41.000
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1051.000
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1001.000
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)1.000
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.999
Tnftumor necrosis factor0.999
Ikbkginhibitor of kappaB kinase gamma0.997
Casp4caspase 4, apoptosis-related cysteine peptidase0.995
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.987
Map3k14mitogen-activated protein kinase kinase kinase 140.967
Ikbkbinhibitor of kappaB kinase beta0.942
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.937
Gata4GATA binding protein 40.829
Rxraretinoid X receptor alpha0.797
PycardPYD and CARD domain containing0.790
Socs1suppressor of cytokine signaling 10.723
Per1period homolog 1 (Drosophila)0.699
Nkx2-3NK2 transcription factor related, locus 3 (Drosophila)0.649
Bcl3B-cell leukemia/lymphoma 30.649
Nlrp3NLR family, pyrin domain containing 30.631
Tlr2toll-like receptor 20.550
Neurog2neurogenin 20.548
Gata6GATA binding protein 60.489
Cd40CD40 antigen0.470
Tnip1TNFAIP3 interacting protein 10.469
Irf1interferon regulatory factor 10.462
Il1binterleukin 1 beta0.461
Cd44CD44 antigen0.421
Icam1intercellular adhesion molecule 10.380
Gbp5guanylate binding protein 50.324
Pax2paired box gene 20.289
Chukconserved helix-loop-helix ubiquitous kinase0.283
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.278
Gata5GATA binding protein 50.267
Cdx2caudal type homeobox 20.261
Map3k8mitogen-activated protein kinase kinase kinase 80.260
Lyz2lysozyme 20.247
Wnt7bwingless-related MMTV integration site 7B0.239
Ticam1toll-like receptor adaptor molecule 10.225
Ighimmunoglobulin heavy chain complex0.211
Trp53transformation related protein 530.208
Vps72vacuolar protein sorting 72 (yeast)0.195
Cyldcylindromatosis (turban tumor syndrome)0.191
Casp1caspase 10.187
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.181
Clec4dC-type lectin domain family 4, member d0.180
2010106G01RikRIKEN cDNA 2010106G01 gene0.180
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.179
Aim2absent in melanoma 20.177
Il1rninterleukin 1 receptor antagonist0.172
Ltbp2latent transforming growth factor beta binding protein 20.172
Cxcl2chemokine (C-X-C motif) ligand 20.167
Il18interleukin 180.163
Tnfsf14tumor necrosis factor (ligand) superfamily, member 140.161
Map3k7mitogen-activated protein kinase kinase kinase 70.156
Ccr1chemokine (C-C motif) receptor 10.156
Foxp3forkhead box P30.149
Gbp2guanylate binding protein 20.140
Tesk1testis specific protein kinase 10.140
ShfSrc homology 2 domain containing F0.137
Birc3baculoviral IAP repeat-containing 30.136
ORF61open reading frame 610.132
Trim28tripartite motif-containing 280.131
Pik3r2phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)0.131
Ephb2Eph receptor B20.127
Myd88myeloid differentiation primary response gene 880.126
Traf6TNF receptor-associated factor 60.124
MefvMediterranean fever0.118
Il7interleukin 70.117
H1fxH1 histone family, member X0.115
Clec4eC-type lectin domain family 4, member e0.113
C1qtnf1C1q and tumor necrosis factor related protein 10.111
Rnf31ring finger protein 310.110
Mta1metastasis associated 10.109
Cxcl13chemokine (C-X-C motif) ligand 130.107
Zfp574zinc finger protein 5740.105
Alx4aristaless-like homeobox 40.104
Plauplasminogen activator, urokinase0.104
Ooepoocyte expressed protein homolog (dog)0.102
Irg1immunoresponsive gene 10.101
Nkain1Na+/K+ transporting ATPase interacting 10.100
Tle6transducin-like enhancer of split 6, homolog of Drosophila E(spl)0.100
Dlx1distal-less homeobox 10.099
E2f1E2F transcription factor 10.099
Slc8a1solute carrier family 8 (sodium/calcium exchanger), member 10.096
Wnt6wingless-related MMTV integration site 60.096
Tax1bp1Tax1 (human T-cell leukemia virus type I) binding protein 10.095
Tnfrsf11btumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)0.091
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.090
Ccl7chemokine (C-C motif) ligand 70.084
Il6interleukin 60.083
Ripk1receptor (TNFRSF)-interacting serine-threonine kinase 10.083
Btbd2BTB (POZ) domain containing 20.082
Gata1GATA binding protein 10.081
Cnih2cornichon homolog 2 (Drosophila)0.079
Git1G protein-coupled receptor kinase-interactor 10.079
Ikzf1IKAROS family zinc finger 10.078
Prap1proline-rich acidic protein 10.078
Tcf3transcription factor 30.077
Chpfchondroitin polymerizing factor0.077
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism