The network for 'regulation of nervous system development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of nervous system development

Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.

NameDescriptionProbabilityFunc Analog Organism
Ras85DRas oncogene at 85D1.000
MadMothers against dpp1.000
Akt1CG4006 gene product from transcript CG4006-RA0.997
shotshort stop0.996
drkdownstream of receptor kinase0.991
trioCG18214 gene product from transcript CG18214-RA0.990
E(spl)Enhancer of split0.988
Pk61CProtein kinase 61C0.983
Eps-15Epidermal growth factor receptor pathway substrate clone 150.982
bratbrain tumor0.981
EcREcdysone receptor0.980
nwknervous wreck0.977
Dap160Dynamin associated protein 1600.977
phlpole hole0.977
slmbsupernumerary limbs0.974
Rho1CG8416 gene product from transcript CG8416-RB0.972
Ptp69DProtein tyrosine phosphatase 69D0.970
CaMKIICalcium/calmodulin-dependent protein kinase II0.966
Pi3K92ECG4141 gene product from transcript CG4141-RB0.961
Applbeta amyloid protein precursor-like0.960
AblAbl tyrosine kinase0.956
aopanterior open0.939
neuroliginCG13772 gene product from transcript CG13772-RA0.936
ik2IkappaB kinase-like 20.927
MED6Mediator complex subunit 60.921
TBPHCG10327 gene product from transcript CG10327-RC0.920
Sema-1aCG18405 gene product from transcript CG18405-RD0.918
Stat92ESignal-transducer and activator of transcription protein at 92E0.917
eyaeyes absent0.909
AlkCG8250 gene product from transcript CG8250-RA0.904
AcslAcyl-CoA synthetase long-chain0.899
Mob2CG11711 gene product from transcript CG11711-RC0.896
MicalMolecule interacting with CasL0.893
witwishful thinking0.888
Mkp3Mitogen-activated protein kinase phosphatase 30.880
KhcKinesin heavy chain0.873
cindrCIN85 and CD2AP orthologue0.872
G-oalpha47AG protein oalpha 47A0.872
MED11Mediator complex subunit 110.861
vvlventral veins lacking0.846
CycECyclin E0.826
numbCG3779 gene product from transcript CG3779-RB0.816
CkIIalphaCasein kinase II alpha subunit0.814
Su(H)Suppressor of Hairless0.799
lolalongitudinals lacking0.795
idaimaginal discs arrested0.790
WASpCG1520 gene product from transcript CG1520-RA0.788
rictorrapamycin-insensitive companion of Tor0.784
aPKCatypical protein kinase C0.774
EphEph receptor tyrosine kinase0.761
CakiCalcium/calmodulin-dependent protein kinase0.750
EgfrEpidermal growth factor receptor0.747
amosabsent MD neurons and olfactory sensilla0.740
S6kRPS6-p70-protein kinase0.736
jebjelly belly0.736
MED4Mediator complex subunit 40.732
ash2absent, small, or homeotic discs 20.729
NFATNFAT homolog0.722
PtenCG5671 gene product from transcript CG5671-RB0.719
HLHm7E(spl) region transcript m70.717
ovoCG6824 gene product from transcript CG6824-RE0.714
zfh1Zn finger homeodomain 10.708
Lim1CG11354 gene product from transcript CG11354-RA0.706
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
vab-3Protein VAB-30.818
pha-4Protein PHA-40.627
egl-18Protein EGL-180.436
unc-73Protein UNC-730.321
ceh-20Protein CEH-200.272
unc-9Protein UNC-90.271
ten-1Protein TEN-10.266
mig-5Protein MIG-50.261
daf-11Protein DAF-110.254
nhr-67Protein NHR-670.251
unc-62Protein UNC-620.213
eya-1Protein EYA-10.205
syg-1Protein SYG-10.188
ina-1Protein INA-10.184
swan-2Protein SWAN-20.173
pkg-1Protein PKG-10.171
chd-7Protein CHD-70.163
T27A3.1Protein T27A3.10.162
egl-30Protein EGL-300.153
ztf-2Protein ZTF-20.152
sma-6Protein SMA-60.152
cst-1Protein CST-10.140
lag-1Protein LAG-10.139
lrp-2Protein LRP-20.134
R10E12.2Protein R10E12.20.128
C11E4.6Protein C11E4.60.126
clh-5Protein CLH-50.126
ncam-1Protein NCAM-10.113
egl-5Protein EGL-50.113
elt-6Protein ELT-60.112
ahr-1Protein AHR-10.110
pry-1Protein PRY-10.109
egl-27Protein EGL-270.108
odr-3Protein ODR-30.101
CELE_R11H6.5Protein R11H6.50.100
unc-70Protein UNC-700.100
sdn-1Protein SDN-10.099
sas-5Protein SAS-50.098
irx-1Protein IRX-10.094
soc-2Protein SOC-20.088
unc-42Protein UNC-420.086
sax-3Protein SAX-30.083
hsr-9Protein HSR-90.082
hlh-2Protein HLH-20.082
gei-4Protein GEI-40.082
F28E10.1Protein F28E10.10.082
lin-11Protein LIN-110.081
sox-2Protein SOX-20.081
zfp-3Protein ZFP-30.079
hcf-1Protein HCF-10.078
pat-3Protein PAT-30.078
mig-2Protein MIG-20.077
tag-303Protein TAG-3030.077
tam-1Protein TAM-10.077
par-3Protein PAR-30.076
lat-1Protein LAT-10.076
pal-1Protein PAL-10.075
mep-1Protein MEP-10.074
pkc-3Protein PKC-30.074
ehs-1Protein EHS-10.074
let-502Protein LET-5020.073
spr-1Protein SPR-10.071
magu-2Protein MAGU-20.068
ain-1Protein AIN-10.066
ceh-27Protein CEH-270.066
vpr-1Protein VPR-10.066
igcm-3Protein IGCM-30.065
syg-2Protein SYG-20.065
inx-19Protein INX-190.064
egl-46Protein EGL-460.064
hmp-1Protein HMP-10.064
K12H4.3Protein K12H4.30.064
dpy-22Protein DPY-220.064
T28F4.1Protein T28F4.10.063
scc-3Protein SCC-30.059
osm-3Protein OSM-30.059
gld-1Protein GLD-10.058
K10C8.3Protein K10C8.30.058
mel-11Protein MEL-110.058
lgc-55Protein LGC-550.058
miz-1Protein MIZ-10.057
C47D12.2Protein C47D12.20.055
che-1Protein CHE-10.055
crm-1Protein CRM-10.054
hnd-1Protein HND-10.054
npr-1Protein NPR-10.054
sem-5Protein SEM-50.053
sel-10Protein SEL-100.053
cnd-1Protein CND-10.053
cey-1Protein CEY-10.052
mec-4Protein MEC-40.052
cam-1Protein CAM-10.051
shn-1Protein SHN-10.051
hgrs-1Protein HGRS-10.051
F29B9.11Protein F29B9.110.051
stip-1Protein STIP-10.050
cst-2Protein CST-20.050
par-5Protein PAR-50.050
sma-9Protein SMA-90.050
dpy-6Protein DPY-60.050
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
cdh2cadherin 2, neuronal0.995
gli1GLI-Kruppel family member 10.979
gli2aGLI-Kruppel family member GLI2a0.946
robo2roundabout homolog 20.946
bocbrother of CDO0.904
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.810
shhasonic hedgehog a0.798
pax2apaired box gene 2a0.791
rarabretinoic acid receptor, alpha b0.780
slc17a6bsolute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b0.769
sox9bSRY-box containing gene 9b0.761
neo1neogenin 10.760
notch3notch homolog 30.739
lef1lymphocyte enhancer binding factor 10.732
lamc1laminin, gamma 10.725
tp53tumor protein p530.713
ptf1apancreas specific transcription factor, 1a0.708
traf4atnf receptor-associated factor 4a0.680
olfm2olfactomedin 20.673
fezf2FEZ family zinc finger 20.665
dccdeleted in colorectal carcinoma0.648
olig2oligodendrocyte lineage transcription factor 20.640
nrp2bneuropilin 2b0.638
col14a1collagen, type XIV, alpha 10.618
hey1hairy/enhancer-of-split related with YRPW motif 10.604
eng2aengrailed 2a0.599
bmp2abone morphogenetic protein 2a0.597
her12hairy-related 120.593
ascl1aachaete-scute complex-like 1a (Drosophila)0.589
fn1fibronectin 10.581
acvr1lactivin A receptor, type I like0.573
sox10SRY-box containing gene 100.572
fgfr2fibroblast growth factor receptor 20.572
ndr2nodal-related 20.567
elavl3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)0.559
pitx3paired-like homeodomain transcription factor 30.545
tcf7l1atranscription factor 7-like 1a (T-cell specific, HMG-box)0.531
wnt11rwingless-type MMTV integration site family, member 11, related0.524
pcdh8protocadherin 80.515
insm1binsulinoma-associated 1b0.502
otx2orthodenticle homolog 20.500
lhx2bLIM homeobox 2b0.484
atoh1aatonal homolog 1a0.483
foxa2forkhead box A20.470
wnt4awingless-type MMTV integration site family, member 4a0.467
phox2apaired-like homeobox 2a0.451
pkd2polycystic kidney disease 20.446
cntn2contactin 20.445
wnt3wingless-type MMTV integration site family, member 30.440
st8sia2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.440
pax7apaired box gene 7a0.438
fzd10frizzled homolog 100.437
six3bsine oculis homeobox homolog 3b0.433
otx1aorthodenticle homolog 1a0.425
flhfloating head0.423
bmpr1aabone morphogenetic protein receptor, type 1aa0.422
lmx1b.1LIM homeobox transcription factor 1, beta 10.417
sncbsynuclein, beta0.414
ptp4a1protein tyrosine phosphatase type IVA, member 10.413
hnf1baHNF1 homeobox Ba0.406
kctd12.1potassium channel tetramerisation domain containing 12.10.398
vsx1visual system homeobox 1 homolog, chx10-like0.395
tbx1T-box 10.392
efnb1ephrin B10.389
sall1asal-like 1a (Drosophila)0.378
nr2f5nuclear receptor subfamily 2, group F, member 50.374
dag1dystroglycan 10.373
sox3SRY-box containing gene 30.371
alcamaactivated leukocyte cell adhesion molecule a0.362
bmp2bbone morphogenetic protein 2b0.362
sp8asp8 transcription factor a0.351
jag1bjagged 1b0.348
ptenbphosphatase and tensin homolog B (mutated in multiple advanced cancers 1)0.338
pax7bpaired box gene 7b0.336
mpzmyelin protein zero0.331
fzd7afrizzled homolog 7a0.325
kdrlkinase insert domain receptor like0.323
wnt11wingless-type MMTV integration site family, member 110.317
fgfr4fibroblast growth factor receptor 40.316
pea3ETS-domain transcription factor pea30.315
ext2exostoses (multiple) 20.313
pcdh19protocadherin 190.313
rxraaretinoid X receptor, alpha a0.312
kal1bKallmann syndrome 1b sequence0.312
epb41l5erythrocyte membrane protein band 4.1 like 50.311
kal1aKallmann syndrome 1a sequence0.311
shhbsonic hedgehog b0.311
sox2SRY-box containing gene 20.304
prdm14PR domain containing 140.304
foxd3forkhead box D30.303
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.302
rargaretinoic acid receptor gamma a0.302
fgf8afibroblast growth factor 8 a0.299
gdf6agrowth differentiation factor 6a0.295
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CDC42cell division cycle 42 (GTP binding protein, 25kDa)1.000
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.976
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.954
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.953
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.942
ATXN1ataxin 10.926
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.926
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.917
FYNFYN oncogene related to SRC, FGR, YES0.913
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.895
RUNX1runt-related transcription factor 10.885
CREBBPCREB binding protein0.885
GSK3Bglycogen synthase kinase 3 beta0.843
HDAC2histone deacetylase 20.828
HDAC1histone deacetylase 10.824
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.802
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.780
SMAD2SMAD family member 20.776
MAPTmicrotubule-associated protein tau0.772
EGFRepidermal growth factor receptor0.765
BCAR1breast cancer anti-estrogen resistance 10.710
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.708
HDAC4histone deacetylase 40.694
ZMYND11zinc finger, MYND-type containing 110.645
PTPN1protein tyrosine phosphatase, non-receptor type 10.641
DLG4discs, large homolog 4 (Drosophila)0.638
RARAretinoic acid receptor, alpha0.630
FGFR1fibroblast growth factor receptor 10.626
SMAD1SMAD family member 10.617
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.591
ITSN1intersectin 1 (SH3 domain protein)0.565
AKT1v-akt murine thymoma viral oncogene homolog 10.562
APCadenomatous polyposis coli0.548
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.543
SCHIP1schwannomin interacting protein 10.532
SKIv-ski sarcoma viral oncogene homolog (avian)0.531
SMAD4SMAD family member 40.524
KCNJ4potassium inwardly-rectifying channel, subfamily J, member 40.518
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.498
BAIAP2BAI1-associated protein 20.476
NTRK3neurotrophic tyrosine kinase, receptor, type 30.466
SMURF2SMAD specific E3 ubiquitin protein ligase 20.465
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.460
NTRK2neurotrophic tyrosine kinase, receptor, type 20.452
QKIquaking homolog, KH domain RNA binding (mouse)0.449
PRMT1protein arginine methyltransferase 10.440
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.435
CCT8chaperonin containing TCP1, subunit 8 (theta)0.429
DNM1dynamin 10.418
SMAD7SMAD family member 70.409
NCOR1nuclear receptor corepressor 10.398
RBPMSRNA binding protein with multiple splicing0.394
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.393
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.389
FN1fibronectin 10.383
PLXNB1plexin B10.359
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.357
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.355
AXIN1axin 10.350
SORBS3sorbin and SH3 domain containing 30.348
KIF23kinesin family member 230.342
NCOA1nuclear receptor coactivator 10.336
MARK2MAP/microtubule affinity-regulating kinase 20.324
GOLGA2golgin A20.319
JAG2jagged 20.314
CRMP1collapsin response mediator protein 10.309
TAL1T-cell acute lymphocytic leukemia 10.308
WIPF1WAS/WASL interacting protein family, member 10.307
CBX8chromobox homolog 80.306
PCGF2polycomb group ring finger 20.302
CTBP1C-terminal binding protein 10.293
RHOAras homolog gene family, member A0.290
PTPN12protein tyrosine phosphatase, non-receptor type 120.289
FASLGFas ligand (TNF superfamily, member 6)0.286
NTNG1netrin G10.282
CUL1cullin 10.282
IQGAP1IQ motif containing GTPase activating protein 10.281
ARHGAP1Rho GTPase activating protein 10.280
JAG1jagged 10.279
TRIOtriple functional domain (PTPRF interacting)0.274
YAP1Yes-associated protein 10.271
FGF1fibroblast growth factor 1 (acidic)0.259
BMPR1Abone morphogenetic protein receptor, type IA0.258
SFRP1secreted frizzled-related protein 10.244
TRIM33tripartite motif containing 330.244
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.241
PTPRCprotein tyrosine phosphatase, receptor type, C0.240
IGF1Rinsulin-like growth factor 1 receptor0.239
MAP2K1mitogen-activated protein kinase kinase 10.235
SPTBN1spectrin, beta, non-erythrocytic 10.230
ARandrogen receptor0.225
SOX21SRY (sex determining region Y)-box 210.225
TRAF5TNF receptor-associated factor 50.224
RXRAretinoid X receptor, alpha0.222
ATN1atrophin 10.218
CBX6chromobox homolog 60.217
KHDRBS1KH domain containing, RNA binding, signal transduction associated 10.217
SORBS2sorbin and SH3 domain containing 20.216
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Grm7glutamate receptor, metabotropic 70.573
Itgamintegrin, alpha M0.470
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.440
Cd9CD9 molecule0.417
Marcksmyristoylated alanine rich protein kinase C substrate0.408
Gria2glutamate receptor, ionotropic, AMPA 20.406
Prss1protease, serine, 1 (trypsin 1)0.399
Jak1Janus kinase 10.393
Junbjun B proto-oncogene0.386
Dnm1dynamin 10.376
Tcf4transcription factor 40.372
Adora2aadenosine A2a receptor0.363
Dlgap1discs, large (Drosophila) homolog-associated protein 10.355
Mllt4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.354
Hspb1heat shock protein 10.345
Map2microtubule-associated protein 20.339
Cugbp2CUG triplet repeat, RNA binding protein 20.326
Il7interleukin 70.324
Nrxn1neurexin 10.320
Ccl2chemokine (C-C motif) ligand 20.306
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.303
Dgkgdiacylglycerol kinase, gamma0.302
Syngap1synaptic Ras GTPase activating protein 1 homolog (rat)0.302
Sv2asynaptic vesicle glycoprotein 2a0.301
Notch1Notch homolog 1, translocation-associated (Drosophila)0.295
Ccl20chemokine (C-C motif) ligand 200.294
Acvr1activin A receptor, type I0.292
Clcn5chloride channel 50.290
Slc12a5solute carrier family 12 (potassium-chloride transporter), member 50.282
Ncam1neural cell adhesion molecule 10.279
Bcl2B-cell CLL/lymphoma 20.276
Arnt2aryl hydrocarbon receptor nuclear translocator 20.275
Lzts1leucine zipper, putative tumor suppressor 10.271
Epb41l1erythrocyte membrane protein band 4.1-like 10.270
Syn2synapsin II0.266
Dlgap3discs, large (Drosophila) homolog-associated protein 30.259
Nrxn3neurexin 30.259
Rap1bRAP1B, member of RAS oncogene family0.253
Galr3galanin receptor 30.251
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.250
Ptprsprotein tyrosine phosphatase, receptor type, S0.249
Prkcgprotein kinase C, gamma0.249
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.247
Nos2nitric oxide synthase 2, inducible0.244
Prl3b1Prolactin family 3, subfamily b, member 10.243
L1camL1 cell adhesion molecule0.239
Accn2amiloride-sensitive cation channel 2, neuronal0.237
Atp2b3ATPase, Ca++ transporting, plasma membrane 30.235
Gja1gap junction protein, alpha 10.234
Cd83CD83 molecule0.234
Lphn2latrophilin 20.233
Spire1spire homolog 1 (Drosophila)0.230
Anxa2annexin A20.230
Nrcamneuronal cell adhesion molecule0.229
Zfp382zinc finger protein 3820.228
Pak2p21 protein (Cdc42/Rac)-activated kinase 20.227
Slc1a1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 10.227
C4bpbcomplement component 4 binding protein, beta0.227
Rdh2retinol dehydrogenase 20.226
Mmp12matrix metallopeptidase 120.226
Fabp2fatty acid binding protein 2, intestinal0.225
Neurog3neurogenin 30.224
Chrnb4cholinergic receptor, nicotinic, beta 40.224
Trib1tribbles homolog 1 (Drosophila)0.224
Cacnb3calcium channel, voltage-dependent, beta 3 subunit0.224
Robo1roundabout homolog 1 (Drosophila)0.222
Stc1stanniocalcin 10.220
Capgcapping protein (actin filament), gelsolin-like0.220
Slit3slit homolog 3 (Drosophila)0.218
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.217
Nfixnuclear factor I/X (CCAAT-binding transcription factor)0.217
Olfm1olfactomedin 10.216
Elk3ELK3, ETS-domain protein0.216
Maptmicrotubule-associated protein tau0.215
Ppp1r2protein phosphatase 1, regulatory (inhibitor) subunit 20.215
Fgfr2fibroblast growth factor receptor 20.214
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.214
Nr4a3nuclear receptor subfamily 4, group A, member 30.214
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.214
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.213
Ddr1discoidin domain receptor tyrosine kinase 10.213
Nr4a2nuclear receptor subfamily 4, group A, member 20.212
Metmet proto-oncogene0.212
Csnk1g3casein kinase 1, gamma 30.211
Tpm3tropomyosin 3, gamma0.210
Grm5glutamate receptor, metabotropic 50.208
Slc6a12solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 120.206
Map1bmicrotubule-associated protein 1B0.205
Pnlippancreatic lipase0.204
Ednrbendothelin receptor type B0.203
Grm8glutamate receptor, metabotropic 80.201
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.200
Muskmuscle, skeletal, receptor tyrosine kinase0.200
Enpp6ectonucleotide pyrophosphatase/phosphodiesterase 60.198
Gria4glutamate receptor, ionotrophic, AMPA 40.198
Tagln3transgelin 30.196
Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.196
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism