The network for 'dorsal ventral axis specification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

dorsal ventral axis specification

The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.

NameDescriptionProbabilityFunc Analog Organism
spn-Bspindle B0.816
CycGCyclin G0.800
BicDBicaudal D0.771
Myd88CG2078 gene product from transcript CG2078-RA0.586
Brca2Breast cancer 2, early onset homolog0.559
ovoCG6824 gene product from transcript CG6824-RE0.558
Src64BSrc oncogene at 64B0.454
Hrb27CHeterogeneous nuclear ribonucleoprotein at 27C0.424
SPESpatzle-Processing Enzyme0.382
cupCG11181 gene product from transcript CG11181-RB0.346
fs(1)K10female sterile (1) K100.340
mus301mutagen-sensitive 3010.339
sogshort gastrulation0.335
Spn27ASerpin 27A0.321
spn-FCG12114 gene product from transcript CG12114-RA0.301
SRPKCG8174 gene product from transcript CG8174-RA0.298
slmbsupernumerary limbs0.270
CG9631CG9631 gene product from transcript CG9631-RA0.267
Mes2CG11100 gene product from transcript CG11100-RB0.264
grassGram-positive Specific Serine protease0.234
CblCG7037 gene product from transcript CG7037-RB0.218
spensplit ends0.217
E2fE2F transcription factor0.211
CG12918CG12918 gene product from transcript CG12918-RA0.188
ImpIGF-II mRNA-binding protein0.185
MadMothers against dpp0.185
PGRP-SAPeptidoglycan recognition protein SA0.176
magomago nashi0.170
EgfrEpidermal growth factor receptor0.170
Sp7Serine protease 70.169
CSN4COP9 complex homolog subunit 40.168
tho2CG31671 gene product from transcript CG31671-RA0.160
eyaeyes absent0.159
Gprk2G protein-coupled receptor kinase 20.158
PGRP-LCPeptidoglycan recognition protein LC0.151
Ser7CG2045 gene product from transcript CG2045-RA0.151
tefutelomere fusion0.145
traltrailer hitch0.140
CG12424CG12424 gene product from transcript CG12424-RC0.137
CG11071CG11071 gene product from transcript CG11071-RA0.131
18w18 wheeler0.126
Spn28DSerpin 28D0.118
Akap200A kinase anchor protein 2000.112
ranCG1404 gene product from transcript CG1404-RB0.111
imdimmune deficiency0.111
CkIalphaCasein kinase Ialpha0.110
Spn1Serine protease inhibitor 10.109
shotshort stop0.109
CSN8COP9 complex homolog subunit 80.109
PGRP-SDCG7496 gene product from transcript CG7496-RA0.106
Msp-300Muscle-specific protein 3000.105
CG31326CG31326 gene product from transcript CG31326-RA0.103
Dsor1Downstream of raf10.101
CG17278CG17278 gene product from transcript CG17278-RA0.094
emcextra macrochaetae0.093
CG9649CG9649 gene product from transcript CG9649-RA0.090
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ndr2nodal-related 20.913
wnt4awingless-type MMTV integration site family, member 4a0.717
tbx1T-box 10.711
lef1lymphocyte enhancer binding factor 10.709
fgf3fibroblast growth factor 30.578
ntn1bnetrin 1b0.509
dkk1bdickkopf 1b0.462
bmp4bone morphogenetic protein 40.460
sox3SRY-box containing gene 30.435
oepone-eyed pinhead0.413
pth2rparathyroid hormone 2 receptor0.381
her5hairy-related 50.359
ntlano tail a0.349
wnt8bwingless-type MMTV integration site family, member 8b0.289
ephb4beph receptor B4b0.282
gli1GLI-Kruppel family member 10.266
spry4sprouty (Drosophila) homolog 40.264
wnt11rwingless-type MMTV integration site family, member 11, related0.200
sox1aSRY-box containing gene 1a0.199
sox17SRY-box containing gene 170.193
ventventral expressed homeobox0.182
sox9aSRY-box containing gene 9a0.179
igf1rbinsulin-like growth factor 1b receptor0.178
sfrp1asecreted frizzled-related protein 1a0.177
sox4bSRY-box containing gene 4b0.170
flhfloating head0.169
msxcmuscle segment homeobox C0.164
wnt10awingless-type MMTV integration site family, member 10a0.160
map2k4amitogen-activated protein kinase kinase 4a0.154
nkx6.2NK6 transcription factor related, locus 20.149
zic3zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)0.143
znf711zinc finger protein 7110.131
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.119
nanos3nanos homolog 30.119
snai1bsnail homolog 1b (Drosophila)0.118
fgf8afibroblast growth factor 8 a0.112
jag2jagged 20.110
bmp2bbone morphogenetic protein 2b0.102
aldh1a2aldehyde dehydrogenase 1 family, member A20.100
hoxd4ahomeo box D4a0.099
wnt2wingless-type MMTV integration site family member 20.099
sox19bSRY-box containing gene 19b0.099
lhx2bLIM homeobox 2b0.096
mosv-mos Moloney murine sarcoma viral oncogene homolog0.095
dusp6dual specificity phosphatase 60.094
bucbucky ball0.092
bmp2abone morphogenetic protein 2a0.090
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.089
wnt7bawingless-type MMTV integration site family, member 7Ba0.087
wnt2bbwingless-type MMTV integration site family, member 2Bb0.086
gli3GLI-Kruppel family member GLI30.086
ca15bcarbonic anhydrase XV b0.080
relv-rel reticuloendotheliosis viral oncogene homolog0.078
pou5f1POU domain, class 5, transcription factor 10.077
foxh1forkhead box H10.077
cdx4caudal type homeo box transcription factor 40.076
shhbsonic hedgehog b0.074
hgfahepatocyte growth factor a0.073
gbx2gastrulation brain homeo box 20.073
otx1borthodenticle homolog 1b0.067
hmx1H6 homeo box 10.067
col2a1acollagen type II, alpha-1a0.066
wnt9bwingless-type MMTV integration site family, member 9B0.065
wnt7bbwingless-type MMTV integration site family, member 7Bb0.063
wnt3wingless-type MMTV integration site family, member 30.063
sema3aasemaphorin 3aa0.062
ptch2patched 20.061
efnb2aephrin B2a0.060
tbx16T-box gene 160.056
extl3exostoses (multiple)-like 30.056
sfrp5secreted frizzled-related protein 50.055
wnt11wingless-type MMTV integration site family, member 110.054
shhasonic hedgehog a0.052
nkx2.5NK2 transcription factor related 50.051
nkx6.1NK6 transcription factor related, locus 1 (Drosophila)0.051
foxg1aforkhead box G1a0.051
lfnglunatic fringe homolog0.051
tmpoathymopoietin a0.049
hhiphedgehog interacting protein0.048
cdh2cadherin 2, neuronal0.047
sp5lSp5 transcription factor-like0.046
wnt7aawingless-type MMTV integration site family, member 7Aa0.045
dazldaz-like gene0.045
dbx1adeveloping brain homeobox 1a0.043
vasavasa homolog0.043
otx2orthodenticle homolog 20.040
her6hairy-related 60.040
sox2SRY-box containing gene 20.040
fgfr1afibroblast growth factor receptor 1a0.039
eng2aengrailed 2a0.038
ippkinositol 1,3,4,5,6-pentakisphosphate 2-kinase0.038
spry2sprouty homolog 20.036
hand2heart and neural crest derivatives expressed transcript 20.035
ndr1nodal-related 10.035
rbpjarecombination signal binding protein for immunoglobulin kappa J region a0.034
gro2groucho 20.033
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SMAD3SMAD family member 30.923
BMPR1Abone morphogenetic protein receptor, type IA0.821
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.718
SMAD1SMAD family member 10.667
SMAD2SMAD family member 20.456
KEAP1kelch-like ECH-associated protein 10.386
BMP2bone morphogenetic protein 20.317
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.299
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.210
C19orf39chromosome 19 open reading frame 390.205
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.186
DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 90.166
RBL2retinoblastoma-like 2 (p130)0.125
EIF4G2eukaryotic translation initiation factor 4 gamma, 20.111
BMP1bone morphogenetic protein 10.108
NFE2L2nuclear factor (erythroid-derived 2)-like 20.104
RAD51L3RAD51-like 3 (S. cerevisiae)0.097
CSNK2A1casein kinase 2, alpha 1 polypeptide0.081
AMMECR1Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 10.080
EIF4A3eukaryotic translation initiation factor 4A30.074
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.071
LIN9lin-9 homolog (C. elegans)0.060
WNT3Awingless-type MMTV integration site family, member 3A0.054
GSK3Bglycogen synthase kinase 3 beta0.054
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.043
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.039
TFDP2transcription factor Dp-2 (E2F dimerization partner 2)0.037
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.037
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.033
CYFIP2cytoplasmic FMR1 interacting protein 20.033
EIF3Aeukaryotic translation initiation factor 3, subunit A0.031
XRCC3X-ray repair complementing defective repair in Chinese hamster cells 30.030
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.030
MAGOHmago-nashi homolog, proliferation-associated (Drosophila)0.029
HNRNPKheterogeneous nuclear ribonucleoprotein K0.029
CSNK2Bcasein kinase 2, beta polypeptide0.028
EIF3Heukaryotic translation initiation factor 3, subunit H0.027
HNRNPCheterogeneous nuclear ribonucleoprotein C (C1/C2)0.026
NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta0.025
APCadenomatous polyposis coli0.025
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.023
SMAD5SMAD family member 50.022
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.022
SMURF2SMAD specific E3 ubiquitin protein ligase 20.021
NLKnemo-like kinase0.021
TRAF4TNF receptor-associated factor 40.020
SMAD7SMAD family member 70.019
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.019
SKILSKI-like oncogene0.019
LRP6low density lipoprotein receptor-related protein 60.018
BCL3B-cell CLL/lymphoma 30.018
SIN3ASIN3 homolog A, transcription regulator (yeast)0.016
RAD52RAD52 homolog (S. cerevisiae)0.016
AXIN1axin 10.015
PRMT1protein arginine methyltransferase 10.015
ZFYVE9zinc finger, FYVE domain containing 90.013
LUC7L2LUC7-like 2 (S. cerevisiae)0.013
BBS10Bardet-Biedl syndrome 100.013
RAD51L1RAD51-like 1 (S. cerevisiae)0.013
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.012
RBL1retinoblastoma-like 1 (p107)0.012
FBLN1fibulin 10.011
RANBP2RAN binding protein 20.011
CSNK1Ecasein kinase 1, epsilon0.010
FSTL1follistatin-like 10.010
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 50.010
HABP4hyaluronan binding protein 40.010
DDOSTdolichyl-diphosphooligosaccharide--protein glycosyltransferase0.010
HNRNPH3heterogeneous nuclear ribonucleoprotein H3 (2H9)0.010
KCNE3potassium voltage-gated channel, Isk-related family, member 30.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Uba52ubiquitin A-52 residue ribosomal protein fusion product 10.012
Ssr4signal sequence receptor, delta0.011
Rpl15ribosomal protein L150.011
Tceb2transcription elongation factor B (SIII), polypeptide 20.011
Rpl31ribosomal protein L310.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism