The network for 'reproductive system development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

reproductive system development

The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.

NameDescriptionProbabilityFunc Analog Organism
smt3CG4494 gene product from transcript CG4494-RA0.881
poloCG12306 gene product from transcript CG12306-RA0.881
Pp1-87BProtein phosphatase 1 at 87B0.869
mxcmulti sex combs0.763
EcREcdysone receptor0.702
Rpd3CG7471 gene product from transcript CG7471-RA0.632
e(y)3enhancer of yellow 30.608
CycBCyclin B0.599
betaTub56Dbeta-Tubulin at 56D0.446
lolalongitudinals lacking0.427
Int6Int6 homologue0.419
Bap60Brahma associated protein 60kD0.409
mus209mutagen-sensitive 2090.405
Su(z)12CG8013 gene product from transcript CG8013-RA0.401
LanB1CG7123 gene product from transcript CG7123-RA0.399
Ptp69DProtein tyrosine phosphatase 69D0.380
Fas2Fasciclin 20.364
Rm62CG10279 gene product from transcript CG10279-RD0.363
NmtN-myristoyl transferase0.360
howheld out wings0.353
bowlbrother of odd with entrails limited0.352
mbcmyoblast city0.342
dallydivision abnormally delayed0.332
hipkhomeodomain interacting protein kinase0.327
RbfRetinoblastoma-family protein0.326
His2AvHistone H2A variant0.324
l(3)01239lethal (3) 012390.311
RanGapRan GTPase activating protein0.309
wocwithout children0.305
dltdiscs lost0.291
CG12259CG12259 gene product from transcript CG12259-RA0.275
CG6724CG6724 gene product from transcript CG6724-RA0.269
BEAF-32Boundary element-associated factor of 32kD0.265
Top2Topoisomerase 20.256
Abd-BAbdominal B0.252
eyaeyes absent0.250
Nipped-ACG33554 gene product from transcript CG33554-RE0.245
zfh1Zn finger homeodomain 10.237
CG7757CG7757 gene product from transcript CG7757-RA0.235
CG4364CG4364 gene product from transcript CG4364-RA0.231
Aos1CG12276 gene product from transcript CG12276-RA0.230
fkhfork head0.230
Rac1CG2248 gene product from transcript CG2248-RA0.226
SmD3Small ribonucleoprotein particle protein SmD30.226
Sin3ACG8815 gene product from transcript CG8815-RC0.225
cv-ccrossveinless c0.222
Btk29ABtk family kinase at 29A0.222
gemininCG3183 gene product from transcript CG3183-RA0.219
CycACyclin A0.215
cicubitus interruptus0.215
ebiCG4063 gene product from transcript CG4063-RA0.207
oddodd skipped0.202
KhcKinesin heavy chain0.200
CG4849CG4849 gene product from transcript CG4849-RA0.196
CG10267CG10267 gene product from transcript CG10267-RB0.190
RpL15Ribosomal protein L150.178
Trip1CG8882 gene product from transcript CG8882-RA0.177
hydhyperplastic discs0.173
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
his-64Protein HIS-640.991
his-62Protein HIS-620.991
hlh-2Protein HLH-20.990
his-46Protein HIS-460.988
his-45Protein HIS-450.987
his-61Protein HIS-610.986
cye-1Protein CYE-10.981
htz-1Protein HTZ-10.978
E02H1.1Protein E02H1.10.976
npp-7Protein NPP-70.974
his-68Protein HIS-680.970
his-47Protein HIS-470.970
his-48Protein HIS-480.970
hcp-3Protein HCP-30.966
mcm-7Protein MCM-70.966
his-16Protein HIS-160.964
his-5Protein HIS-50.963
mat-3Protein MAT-30.960
his-1Protein HIS-10.958
his-59Protein HIS-590.949
his-30Protein HIS-300.946
his-29Protein HIS-290.945
lin-35Protein LIN-350.941
his-50Protein HIS-500.938
gpr-1Protein GPR-10.937
hcp-6Protein HCP-60.934
his-42Protein HIS-420.933
his-31Protein HIS-310.931
egl-18Protein EGL-180.930
hpl-2Protein HPL-20.918
emb-5Protein EMB-50.904
prp-8Protein PRP-80.903
lin-53Protein LIN-530.896
his-32Protein HIS-320.893
cam-1Protein CAM-10.891
lin-29Protein LIN-290.891
cacn-1Protein CACN-10.883
dao-5Protein DAO-50.878
wrm-1Protein WRM-10.876
mes-4Protein MES-40.871
pha-4Protein PHA-40.869
bar-1Protein BAR-10.869
lin-12Protein LIN-120.858
egl-13Protein EGL-130.855
cul-1Protein CUL-10.854
pro-1Protein PRO-10.849
kin-3Protein KIN-30.846
mig-5Protein MIG-50.837
swsn-2.1Protein SWSN-2.10.836
pri-1Protein PRI-10.831
xpo-2Protein XPO-20.831
unc-54Protein UNC-540.830
gex-3Protein GEX-30.827
ztf-2Protein ZTF-20.825
smc-3Protein SMC-30.824
kle-2Protein KLE-20.823
rpb-2Protein RPB-20.821
rsa-1Protein RSA-10.820
vbh-1Protein VBH-10.817
spdl-1Protein SPDL-10.814
zen-4Protein ZEN-40.813
CELE_T26G10.1Protein T26G10.10.811
his-2Protein HIS-20.811
unc-6Protein UNC-60.809
rpa-2Protein RPA-20.805
rpn-1Protein RPN-10.804
ZK930.1Protein ZK930.10.803
klp-16Protein KLP-160.801
zyg-8Protein ZYG-80.799
prp-21Protein PRP-210.798
pro-2Protein PRO-20.796
gla-3Protein GLA-30.793
elt-6Protein ELT-60.789
nhr-67Protein NHR-670.787
isw-1Protein ISW-10.783
scc-1Protein SCC-10.782
mcm-5Protein MCM-50.777
unc-59Protein UNC-590.776
nasp-2Protein NASP-20.773
klp-19Protein KLP-190.772
unc-37Protein UNC-370.772
prp-3Protein PRP-30.771
mag-1Protein MAG-10.770
F25B3.6Protein F25B3.60.768
npp-21Protein NPP-210.768
vrk-1Protein VRK-10.764
vab-3Protein VAB-30.760
zip-7Protein ZIP-70.757
lsy-2Protein LSY-20.756
nhr-25Protein NHR-250.752
lrr-1Protein LRR-10.746
unc-62Protein UNC-620.741
hmp-2Protein HMP-20.740
CELE_Y95D11A.1Protein Y95D11A.10.738
unc-53Protein UNC-530.737
fbf-2Protein FBF-20.734
bir-1Protein BIR-10.730
col-34Protein COL-340.730
T23D8.3Protein T23D8.30.723
ben-1Protein BEN-10.723
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
sf3b1splicing factor 3b, subunit 10.051
shhasonic hedgehog a0.037
eng2aengrailed 2a0.036
pax2apaired box gene 2a0.033
mibmind bomb0.030
ptch2patched 20.030
ssrp1astructure specific recognition protein 1a0.022
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.022
rpsaribosomal protein SA0.022
bmp4bone morphogenetic protein 40.021
eif3geukaryotic translation initiation factor 3, subunit G0.020
ruvbl2RuvB-like 2 (E. coli)0.019
zic1zic family member 1 (odd-paired homolog, Drosophila)0.018
pbx4pre-B-cell leukemia transcription factor 40.018
cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.018
foxg1aforkhead box G1a0.018
smc4structural maintenance of chromosomes 40.018
lef1lymphocyte enhancer binding factor 10.018
cyp11a1cytochrome P450, subfamily XIA, polypeptide 10.017
tp53tumor protein p530.017
sox3SRY-box containing gene 30.016
rfx2regulatory factor X, 2 (influences HLA class II expression)0.016
hspa9heat shock protein 90.015
sox2SRY-box containing gene 20.015
robo3roundabout homolog 30.014
axin1axin 10.014
fgfr3fibroblast growth factor receptor 30.014
eif3deukaryotic translation initiation factor 3, subunit D0.014
melkmaternal embryonic leucine zipper kinase0.013
bms1lBMS1-like, ribosome assembly protein (yeast)0.013
wlswntless homolog (Drosophila)0.013
eif3eaeukaryotic translation initiation factor 3, subunit E, a0.013
ascl1aachaete-scute complex-like 1a (Drosophila)0.012
hnrplheterogeneous nuclear ribonucleoprotein L0.012
cdc26cell division cycle 26 homolog0.012
pax7apaired box gene 7a0.012
csnk1a1casein kinase 1, alpha 10.012
sox19aSRY-box containing gene 19a0.012
cyp19a1acytochrome P450, family 19, subfamily A, polypeptide 1a0.012
rcc2regulator of chromosome condensation 20.011
six3bsine oculis homeobox homolog 3b0.011
cct7chaperonin containing TCP1, subunit 7 (eta)0.011
zff9zinc finger protein 90.011
fgfrl1bfibroblast growth factor receptor-like 1b0.011
acvr2bactivin receptor IIb0.011
rspo1R-spondin homolog (Xenopus laevis)0.011
restRE1-silencing transcription factor0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TP53tumor protein p530.998
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.974
HNRNPUL1heterogeneous nuclear ribonucleoprotein U-like 10.857
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.767
AHSA1AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)0.710
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.659
SNW1SNW domain containing 10.638
EGFRepidermal growth factor receptor0.580
RUVBL2RuvB-like 2 (E. coli)0.495
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.489
DDX5DEAD (Asp-Glu-Ala-Asp) box polypeptide 50.478
PRMT5protein arginine methyltransferase 50.465
MCM7minichromosome maintenance complex component 70.426
EIF4A3eukaryotic translation initiation factor 4A30.418
SNIP1Smad nuclear interacting protein 10.418
NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)0.412
CREBBPCREB binding protein0.406
ESR1estrogen receptor 10.402
GSK3Bglycogen synthase kinase 3 beta0.393
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.388
NCOR1nuclear receptor corepressor 10.375
CSNK2A1casein kinase 2, alpha 1 polypeptide0.367
TCEB1transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)0.361
SP1Sp1 transcription factor0.352
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.334
ELAVL1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.327
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.325
SMAD4SMAD family member 40.325
ACTBactin, beta0.315
FGFR1fibroblast growth factor receptor 10.314
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.314
HNF4Ahepatocyte nuclear factor 4, alpha0.313
CTNNBL1catenin, beta like 10.297
NUDCnuclear distribution gene C homolog (A. nidulans)0.285
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.276
PRPF3PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)0.261
SEPT2septin 20.260
COPS3COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)0.259
SKP2S-phase kinase-associated protein 2 (p45)0.246
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.244
SF3A2splicing factor 3a, subunit 2, 66kDa0.241
ZHX1zinc fingers and homeoboxes 10.237
HSPA8heat shock 70kDa protein 80.237
RBBP4retinoblastoma binding protein 40.230
MAGOHmago-nashi homolog, proliferation-associated (Drosophila)0.224
HDAC2histone deacetylase 20.219
EFTUD2elongation factor Tu GTP binding domain containing 20.214
RBM8ARNA binding motif protein 8A0.208
THOC4THO complex 40.196
PRPF19PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)0.195
SKP1S-phase kinase-associated protein 10.193
SMC3structural maintenance of chromosomes 30.190
APCadenomatous polyposis coli0.190
EIF2C2eukaryotic translation initiation factor 2C, 20.186
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)0.186
MTA1metastasis associated 10.185
RBM39RNA binding motif protein 390.185
ANAPC5anaphase promoting complex subunit 50.170
UBE2Mubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)0.169
ICT1immature colon carcinoma transcript 10.165
HSPE1heat shock 10kDa protein 1 (chaperonin 10)0.164
EIF3Geukaryotic translation initiation factor 3, subunit G0.164
CDC27cell division cycle 27 homolog (S. cerevisiae)0.163
POLA1polymerase (DNA directed), alpha 1, catalytic subunit0.163
PTPN1protein tyrosine phosphatase, non-receptor type 10.159
PKM2pyruvate kinase, muscle0.157
ZFYVE9zinc finger, FYVE domain containing 90.153
SMC1Astructural maintenance of chromosomes 1A0.153
BRCA1breast cancer 1, early onset0.151
STAG2stromal antigen 20.150
NAP1L1nucleosome assembly protein 1-like 10.149
NSA2NSA2 ribosome biogenesis homolog (S. cerevisiae)0.147
CAND1cullin-associated and neddylation-dissociated 10.147
RPL5ribosomal protein L50.143
RNPS1RNA binding protein S1, serine-rich domain0.143
CCNB1cyclin B10.142
RUVBL1RuvB-like 1 (E. coli)0.139
EZH2enhancer of zeste homolog 2 (Drosophila)0.138
CAV1caveolin 1, caveolae protein, 22kDa0.137
NOTCH1notch 10.137
NCOR2nuclear receptor corepressor 20.136
NACAnascent polypeptide-associated complex alpha subunit0.135
RB1retinoblastoma 10.135
CSNK2Bcasein kinase 2, beta polypeptide0.135
PRPF31PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)0.134
RBFOX2RNA binding protein, fox-1 homolog (C. elegans) 20.133
BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)0.132
FGFR2fibroblast growth factor receptor 20.130
IDH3Bisocitrate dehydrogenase 3 (NAD+) beta0.129
POLR2Epolymerase (RNA) II (DNA directed) polypeptide E, 25kDa0.129
EIF2S1eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa0.128
CCT7chaperonin containing TCP1, subunit 7 (eta)0.128
SRSF2serine/arginine-rich splicing factor 20.125
RAE1RAE1 RNA export 1 homolog (S. pombe)0.125
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.124
NIPBLNipped-B homolog (Drosophila)0.123
EBNA1BP2EBNA1 binding protein 20.122
WDR77WD repeat domain 770.122
SMAD3SMAD family member 30.122
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Eef2eukaryotic translation elongation factor 20.468
Fut1fucosyltransferase 10.463
Tgfbr2transforming growth factor, beta receptor II0.436
Gata3GATA binding protein 30.423
LOC100360587hypothetical protein LOC1003605870.423
Bmp6bone morphogenetic protein 60.420
Cyp1b1cytochrome P450, family 1, subfamily b, polypeptide 10.386
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.386
Gja5gap junction protein, alpha 50.386
Gja3gap junction protein, alpha 30.373
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.348
Bcl2B-cell CLL/lymphoma 20.346
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.330
Vdrvitamin D (1,25- dihydroxyvitamin D3) receptor0.302
Stat3signal transducer and activator of transcription 30.301
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.292
Gjb3gap junction protein, beta 30.274
Shc3SHC (Src homology 2 domain containing) transforming protein 30.273
Rararetinoic acid receptor, alpha0.272
Col10a1collagen, type X, alpha 10.269
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.265
Gata6GATA binding protein 60.265
Ss18l1synovial sarcoma translocation gene on chromosome 18-like 10.263
Homer3homer homolog 3 (Drosophila)0.259
Smad7SMAD family member 70.259
Igfbp5insulin-like growth factor binding protein 50.244
Nkx2-1NK2 homeobox 10.241
Chrm1cholinergic receptor, muscarinic 10.241
Hsd3b6hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 60.239
Nr5a2nuclear receptor subfamily 5, group A, member 20.229
G6pcglucose-6-phosphatase, catalytic subunit0.227
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.226
Aqp2aquaporin 2 (collecting duct)0.220
Socs3suppressor of cytokine signaling 30.218
Tcof1Treacher Collins-Franceschetti syndrome 1 homolog (human)0.212
Fn1fibronectin 10.212
Pdgfbplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.202
Hnf1bHNF1 homeobox B0.195
Casp3caspase 30.190
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.185
Bmp7bone morphogenetic protein 70.185
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.182
Prdx1peroxiredoxin 10.181
Mcm6minichromosome maintenance complex component 60.180
Fabp6fatty acid binding protein 6, ileal0.177
Serpine2serine (or cysteine) peptidase inhibitor, clade E, member 20.175
S1pr2sphingosine-1-phosphate receptor 20.173
Prkar2aprotein kinase, cAMP dependent regulatory, type II alpha0.172
Cpxm2carboxypeptidase X (M14 family), member 20.169
RT1-M5RT1 class Ib, locus M50.168
Cd14CD14 molecule0.166
Scnn1bsodium channel, nonvoltage-gated 1, beta0.165
Nrg1neuregulin 10.165
Serpina5serine (or cysteine) peptidase inhibitor, clade A, member 50.165
Egfrepidermal growth factor receptor0.163
Slc18a3solute carrier family 18 (vesicular acetylcholine), member 30.162
Nab1Ngfi-A binding protein 10.159
Icam1intercellular adhesion molecule 10.159
Cd44Cd44 molecule0.157
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.155
Sod3superoxide dismutase 3, extracellular0.153
Foxe1forkhead box E1 (thyroid transcription factor 2)0.151
LOC257643cystatin SC0.149
Krt18keratin 180.149
Id3inhibitor of DNA binding 30.149
Strnstriatin, calmodulin binding protein0.148
Pde3aphosphodiesterase 3A, cGMP inhibited0.148
LOC100361571keratin associated protein 1-3-like0.148
Timp1TIMP metallopeptidase inhibitor 10.147
Ccr1chemokine (C-C motif) receptor 10.147
Il13ra1interleukin 13 receptor, alpha 10.146
Kcng2potassium voltage-gated channel, subfamily G, member 20.145
Agtr1aangiotensin II receptor, type 1a0.145
Svs5seminal vesicle secretory protein 50.144
Cald1caldesmon 10.144
Ppardperoxisome proliferator-activated receptor delta0.140
Il6interleukin 60.140
Ier3immediate early response 30.139
Ddr2discoidin domain receptor tyrosine kinase 20.138
Il1r1interleukin 1 receptor, type I0.138
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.137
Pparaperoxisome proliferator activated receptor alpha0.135
Kcng3potassium voltage-gated channel, subfamily G, member 30.135
MrgprfMAS-related GPR, member F0.133
Map3k3mitogen activated protein kinase kinase kinase 30.132
Shc2SHC (Src homology 2 domain containing) transforming protein 20.131
Slc22a9solute carrier family 22 (organic anion transporter), member 90.131
Ppypancreatic polypeptide0.131
Lig3ligase III, DNA, ATP-dependent0.131
Anxa2annexin A20.130
Tas2r107taste receptor, type 2, member 1070.130
Crygccrystallin, gamma C0.130
Cdc25acell division cycle 25 homolog A (S. pombe)0.129
Hand2heart and neural crest derivatives expressed 20.128
Jak2Janus kinase 20.128
Adcy5adenylate cyclase 50.128
Nefmneurofilament, medium polypeptide0.127
Casp12caspase 120.126
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism