The network for 'heterochromatin organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

heterochromatin organization

Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin.

NameDescriptionProbabilityFunc Analog Organism
CTCFCG8591 gene product from transcript CG8591-RA0.989
Su(var)2-10Suppressor of variegation 2-100.947
eggeggless0.930
HsfHeat shock factor0.923
SuURSuppressor of Under-Replication0.890
JIL-1CG6297 gene product from transcript CG6297-RA0.866
Su(var)2-HP2CG12864 gene product from transcript CG12864-RB0.863
Su(var)3-7Suppressor of variegation 3-70.858
BEAF-32Boundary element-associated factor of 32kD0.847
MBD-likeCG8208 gene product from transcript CG8208-RA0.774
Jarid2CG3654 gene product from transcript CG3654-RD0.757
pzgputzig0.716
Mekk1CG7717 gene product from transcript CG7717-RB0.687
E(var)3-9Enhancer of variegation 3-90.539
Hel25EHelicase at 25E0.517
jumujumeau0.499
wdewindei0.447
vasvasa0.393
piwiCG6122 gene product from transcript CG6122-RA0.393
Top2Topoisomerase 20.382
ChroChromator0.380
Su(var)3-3Suppressor of variegation 3-30.342
asf1anti-silencing factor 10.342
pds5CG17509 gene product from transcript CG17509-RA0.322
Sir2CG5216 gene product from transcript CG5216-RA0.313
D1D1 chromosomal protein0.259
chmchameau0.254
stilstand still0.252
CG5794CG5794 gene product from transcript CG5794-RB0.239
SMC1CG6057 gene product from transcript CG6057-RA0.202
Acf1ATP-dependent chromatin assembly factor large subunit0.198
Cap-H2Chromosome associated protein H20.192
Mi-2CG8103 gene product from transcript CG8103-RA0.182
CG13022CG13022 gene product from transcript CG13022-RB0.166
SdcSyndecan0.155
E(bx)Enhancer of bithorax0.154
msl-3male-specific lethal 30.144
PcPolycomb0.140
HmgDHigh mobility group protein D0.137
mofmales absent on the first0.122
IswiImitation SWI0.108
CG5899CG5899 gene product from transcript CG5899-RA0.108
Chd1Chromodomain-helicase-DNA-binding protein 10.106
MED6Mediator complex subunit 60.105
AGO2Argonaute 20.103
RanBPMRan-binding protein M0.103
pashapartner of drosha0.103
chicoCG5686 gene product from transcript CG5686-RB0.101
pr-set7CG3307 gene product from transcript CG3307-RC0.100
Mt2Methyltransferase 20.096
XNPCG4548 gene product from transcript CG4548-RA0.092
Cap-GCG34438 gene product from transcript CG34438-RF0.090
ird5immune response deficient 50.088
rhirhino0.079
CG12256CG12256 gene product from transcript CG12256-RA0.078
hklhook-like0.075
CG5261CG5261 gene product from transcript CG5261-RB0.075
l(3)73Ahlethal (3) 73Ah0.073
r2d2CG7138 gene product from transcript CG7138-RB0.072
CG11138CG11138 gene product from transcript CG11138-RC0.070
Df31Decondensation factor 310.069
CG13350CG13350 gene product from transcript CG13350-RA0.068
stwlstonewall0.065
gktglaikit0.063
SceSex combs extra0.063
hdhumpty dumpty0.063
Gef26CG9491 gene product from transcript CG9491-RB0.060
mbf1multiprotein bridging factor 10.057
bambag of marbles0.054
HiraCG12153 gene product from transcript CG12153-RA0.054
Mcm10Sensitized chromosome inheritance modifier 190.054
Rpd3CG7471 gene product from transcript CG7471-RA0.053
Eip63EEcdysone-induced protein 63E0.052
rasraspberry0.051
encencore0.050
Taf7TBP-associated factor 70.049
CG5844CG5844 gene product from transcript CG5844-RA0.048
CG11866CG11866 gene product from transcript CG11866-RA0.048
trrtrithorax-related0.048
CG14053CG14053 gene product from transcript CG14053-RA0.048
CG5641CG5641 gene product from transcript CG5641-RA0.046
CG8319CG8319 gene product from transcript CG8319-RA0.046
CG14711CG14711 gene product from transcript CG14711-RA0.044
CG3760CG3760 gene product from transcript CG3760-RB0.042
twinCG31137 gene product from transcript CG31137-RB0.042
Gcn2CG1609 gene product from transcript CG1609-RA0.041
Gr28bGustatory receptor 28b0.041
Su(var)205Suppressor of variegation 2050.040
CG14182CG14182 gene product from transcript CG14182-RA0.040
CG14438CG14438 gene product from transcript CG14438-RA0.038
Nf1Neurofibromin 10.038
fs(1)Ybfemale sterile (1) Yb0.038
CG3638CG3638 gene product from transcript CG3638-RE0.037
HmrHybrid male rescue0.037
CG10576CG10576 gene product from transcript CG10576-RA0.037
Cul-5Cullin-50.037
bgcnbenign gonial cell neoplasm0.037
CG15141CG15141 gene product from transcript CG15141-RA0.037
HP4Heterochromatin protein 40.036
CG10880CG10880 gene product from transcript CG10880-RA0.036
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CBX5chromobox homolog 50.758
CBX1chromobox homolog 10.696
POLE2polymerase (DNA directed), epsilon 2 (p59 subunit)0.688
POLE3polymerase (DNA directed), epsilon 3 (p17 subunit)0.569
CBX3chromobox homolog 30.520
BAZ1Bbromodomain adjacent to zinc finger domain, 1B0.261
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.189
CHAF1Bchromatin assembly factor 1, subunit B (p60)0.169
MBD1methyl-CpG binding domain protein 10.097
HIST1H3Bhistone cluster 1, H3b0.088
E2F3E2F transcription factor 30.081
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.072
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.064
CHAF1Achromatin assembly factor 1, subunit A (p150)0.063
TAF10TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa0.058
RIF1RAP1 interacting factor homolog (yeast)0.057
LBRlamin B receptor0.047
SYNCRIPsynaptotagmin binding, cytoplasmic RNA interacting protein0.045
CHRAC1chromatin accessibility complex 10.041
POGZpogo transposable element with ZNF domain0.032
CDC7cell division cycle 7 homolog (S. cerevisiae)0.032
TOP1topoisomerase (DNA) I0.031
PRRC2Cproline-rich coiled-coil 2C0.030
FAM46Afamily with sequence similarity 46, member A0.027
SSBSjogren syndrome antigen B (autoantigen La)0.027
TPRtranslocated promoter region (to activated MET oncogene)0.026
PRMT6protein arginine methyltransferase 60.025
DICER1dicer 1, ribonuclease type III0.025
ADNPactivity-dependent neuroprotector homeobox0.025
INCENPinner centromere protein antigens 135/155kDa0.022
NCLnucleolin0.022
CYFIP2cytoplasmic FMR1 interacting protein 20.021
LRIF1ligand dependent nuclear receptor interacting factor 10.019
NSL1NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)0.019
ARID1AAT rich interactive domain 1A (SWI-like)0.018
POLE4polymerase (DNA-directed), epsilon 4 (p12 subunit)0.018
SMC3structural maintenance of chromosomes 30.015
CYFIP1cytoplasmic FMR1 interacting protein 10.015
YBX1Y box binding protein 10.015
SGOL1shugoshin-like 1 (S. pombe)0.015
LDOC1leucine zipper, down-regulated in cancer 10.014
ZNF638zinc finger protein 6380.014
RAD21RAD21 homolog (S. pombe)0.013
AP1M1adaptor-related protein complex 1, mu 1 subunit0.012
UHRF1ubiquitin-like with PHD and ring finger domains 10.012
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.011
RSF1remodeling and spacing factor 10.011
CARM1coactivator-associated arginine methyltransferase 10.011
CEP72centrosomal protein 72kDa0.011
DR1down-regulator of transcription 1, TBP-binding (negative cofactor 2)0.011
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.010
NUCKS1nuclear casein kinase and cyclin-dependent kinase substrate 10.010
MYCNv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Smarca5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 50.967
Smc3structural maintenace of chromosomes 30.803
Trim24tripartite motif-containing 240.776
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.752
Baz1bbromodomain adjacent to zinc finger domain, 1B0.697
Smc1astructural maintenance of chromosomes 1A0.677
Rnf2ring finger protein 20.620
Baz1abromodomain adjacent to zinc finger domain 1A0.531
Nucks1nuclear casein kinase and cyclin-dependent kinase substrate 10.526
Fmr1fragile X mental retardation syndrome 1 homolog0.509
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.433
Mcm4minichromosome maintenance deficient 4 homolog (S. cerevisiae)0.369
Timelesstimeless homolog (Drosophila)0.359
Chaf1achromatin assembly factor 1, subunit A (p150)0.353
Dkc1dyskeratosis congenita 1, dyskerin homolog (human)0.340
Kdm2blysine (K)-specific demethylase 2B0.324
Suz12suppressor of zeste 12 homolog (Drosophila)0.298
Mms22lMMS22-like, DNA repair protein0.287
Pold1polymerase (DNA directed), delta 1, catalytic subunit0.264
Thoc2THO complex 20.232
Brca2breast cancer 20.228
Cbx5chromobox homolog 5 (Drosophila HP1a)0.216
Casp8ap2caspase 8 associated protein 20.197
Chek1checkpoint kinase 1 homolog (S. pombe)0.195
C330027C09RikRIKEN cDNA C330027C09 gene0.194
Nup155nucleoporin 1550.181
Dnmt3aDNA methyltransferase 3A0.180
Haus6HAUS augmin-like complex, subunit 60.156
Hnrnpmheterogeneous nuclear ribonucleoprotein M0.156
Smc2structural maintenance of chromosomes 20.131
Syncripsynaptotagmin binding, cytoplasmic RNA interacting protein0.114
Hnrnpuheterogeneous nuclear ribonucleoprotein U0.108
Fxr1fragile X mental retardation gene 1, autosomal homolog0.102
Ezh2enhancer of zeste homolog 2 (Drosophila)0.099
Ncapg2non-SMC condensin II complex, subunit G20.097
Ppigpeptidyl-prolyl isomerase G (cyclophilin G)0.094
Anp32bacidic (leucine-rich) nuclear phosphoprotein 32 family, member B0.094
MgaMAX gene associated0.093
Creb1cAMP responsive element binding protein 10.086
Smc6structural maintenance of chromosomes 60.085
Cenpc1centromere protein C10.085
Dnmt3bDNA methyltransferase 3B0.073
Srsf7serine/arginine-rich splicing factor 70.068
Hellshelicase, lymphoid specific0.063
Ddx10DEAD (Asp-Glu-Ala-Asp) box polypeptide 100.061
Cbx1chromobox homolog 1 (Drosophila HP1 beta)0.061
Dtldenticleless homolog (Drosophila)0.060
Cdc7cell division cycle 7 (S. cerevisiae)0.060
Rif1Rap1 interacting factor 1 homolog (yeast)0.058
Cdca7lcell division cycle associated 7 like0.056
Anp32eacidic (leucine-rich) nuclear phosphoprotein 32 family, member E0.056
Mcm2minichromosome maintenance deficient 2 mitotin (S. cerevisiae)0.052
BlmBloom syndrome, RecQ helicase-like0.051
Ccne2cyclin E20.051
Dnmt3lDNA (cytosine-5-)-methyltransferase 3-like0.047
Cbx7chromobox homolog 70.047
Myef2myelin basic protein expression factor 2, repressor0.047
Terf1telomeric repeat binding factor 10.046
Bclaf1BCL2-associated transcription factor 10.045
Taf3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor0.045
RybpRING1 and YY1 binding protein0.044
Rcan1regulator of calcineurin 10.044
Atad2ATPase family, AAA domain containing 20.043
Plk4polo-like kinase 4 (Drosophila)0.043
Csnk2a1casein kinase 2, alpha 1 polypeptide0.042
Dhx15DEAH (Asp-Glu-Ala-His) box polypeptide 150.042
Ddx46DEAD (Asp-Glu-Ala-Asp) box polypeptide 460.042
Arid4bAT rich interactive domain 4B (RBP1-like)0.041
Larp7La ribonucleoprotein domain family, member 70.041
Hcfc1host cell factor C10.041
Srsf1serine/arginine-rich splicing factor 10.040
Klhl24kelch-like 24 (Drosophila)0.040
Donsondownstream neighbor of SON0.040
L3mbtl2l(3)mbt-like 2 (Drosophila)0.039
Tmpothymopoietin0.039
Cdt1chromatin licensing and DNA replication factor 10.038
Stag1stromal antigen 10.038
Mis18bp1MIS18 binding protein 10.037
Eif4g1eukaryotic translation initiation factor 4, gamma 10.037
Ncaphnon-SMC condensin I complex, subunit H0.037
Lig1ligase I, DNA, ATP-dependent0.037
Dhx9DEAH (Asp-Glu-Ala-His) box polypeptide 90.036
Brca1breast cancer 10.036
Maelmaelstrom homolog (Drosophila)0.036
Usp7ubiquitin specific peptidase 70.035
Mcm6minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)0.035
Orc1origin recognition complex, subunit 10.035
Dckdeoxycytidine kinase0.034
Arid1bAT rich interactive domain 1B (SWI-like)0.033
G2e3G2/M-phase specific E3 ubiquitin ligase0.033
Smad5MAD homolog 5 (Drosophila)0.033
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.033
Lin9lin-9 homolog (C. elegans)0.032
Zbtb33zinc finger and BTB domain containing 330.032
Xrn15'-3' exoribonuclease 10.031
Cdca7cell division cycle associated 70.031
Mtf2metal response element binding transcription factor 20.031
Phippleckstrin homology domain interacting protein0.031
BcorBCL6 interacting corepressor0.029
Cstf2cleavage stimulation factor, 3' pre-RNA subunit 20.028
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
RCO1Rco1p0.069
DLS1Dls1p0.047
CHD1Chd1p0.043
RSC2Rsc2p0.039
ITC1Itc1p0.035
BDF2Bdf2p0.033
RLF2Rlf2p0.031
SWR1Swr1p0.030
NUP157Nup157p0.026
STH1Sth1p0.026
ADA2Ada2p0.024
SWI1Swi1p0.024
TRA1Tra1p0.024
HDA2Hda2p0.024
SPT20Spt20p0.022
SWC7Swc7p0.020
YLR278Chypothetical protein0.020
RSC30Rsc30p0.019
SWC3Swc3p0.019
SMC6Smc6p0.018
SRD1Srd1p0.018
EXO1Exo1p0.018
IOC2Ioc2p0.017
NGG1Ngg1p0.017
YIL151Chypothetical protein0.016
LEO1Leo1p0.016
REV1Rev1p0.016
YLR264C-Ahypothetical protein0.016
BDF1Bdf1p0.015
ASF1Asf1p0.015
CUP1-1Cup1-1p0.015
ARP10Arp10p0.015
CRP1Crp1p0.015
YOL038C-Ahypothetical protein0.015
YLR419Whypothetical protein0.015
MER1Mer1p0.015
LEU2Leu2p0.014
NSP1Nsp1p0.014
YLR162Whypothetical protein0.014
SMC4Smc4p0.014
YAR068Whypothetical protein0.014
EPL1Epl1p0.014
HXT3Hxt3p0.013
RSC8Rsc8p0.013
YPR157Whypothetical protein0.013
NUP188Nup188p0.013
CAC2Cac2p0.013
MOT1Mot1p0.013
TAF12Taf12p0.013
MDN1Mdn1p0.013
ZPS1Zps1p0.013
YLR042Chypothetical protein0.013
ISW1Isw1p0.013
HPF1Hpf1p0.012
ATP6Atp6p0.012
SAS3Sas3p0.012
URA3Ura3p0.012
SPL2Spl2p0.012
ARG8Arg8p0.012
YBR013Chypothetical protein0.012
FMT1Fmt1p0.012
YIR035Chypothetical protein0.012
SFT1Sft1p0.012
HOHop0.012
TAF7Taf7p0.012
AUA1Aua1p0.012
YCL021W-Ahypothetical protein0.011
TRI1Tri1p0.011
RTT107Rtt107p0.011
RTT106Rtt106p0.011
INO80Ino80p0.011
POB3Pob3p0.011
YKR075Chypothetical protein0.011
AQY2Aqy2p0.011
BSC1Bsc1p0.011
IZH4Izh4p0.011
DIC1Dic1p0.011
POL2Pol2p0.011
YOL013W-Ahypothetical protein0.011
BRN1Brn1p0.011
PRS2Prs2p0.011
YBL044Whypothetical protein0.010
MF(ALPHA)2Mf(alpha)2p0.010
NHA1Nha1p0.010
ALT2Alt2p0.010
TYE7Tye7p0.010
YLR040Chypothetical protein0.010
TIF4632Tif4632p0.010
SPO74Spo74p0.010
DUR1,2Dur1,2p0.010
SCM4Scm4p0.010
YKR041Whypothetical protein0.010
RFC2Rfc2p0.010
YJL181Whypothetical protein0.010
CHA1Cha1p0.010