The network for 'positive regulation of nucleobase containing compound metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of nucleobase containing compound metabolic process

Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

NameDescriptionProbabilityFunc Analog Organism
Akt1CG4006 gene product from transcript CG4006-RA1.000
UbxUltrabithorax0.998
Snr1Snf5-related 10.988
mysmyospheroid0.986
EcREcdysone receptor0.986
NNotch0.983
hthhomothorax0.971
Pi3K92ECG4141 gene product from transcript CG4141-RB0.970
InRInsulin-like receptor0.968
dadaughterless0.967
trxtrithorax0.959
panpangolin0.956
mormoira0.947
DadDaughters against dpp0.938
e(y)3enhancer of yellow 30.934
dacdachshund0.933
wgwingless0.928
MadMothers against dpp0.921
osaCG7467 gene product from transcript CG7467-RD0.920
dcodiscs overgrown0.916
Rac2CG8556 gene product from transcript CG8556-RA0.915
PtenCG5671 gene product from transcript CG5671-RB0.913
bcdbicoid0.908
DllDistal-less0.908
nmonemo0.903
TER94CG2331 gene product from transcript CG2331-RA0.899
MedMedea0.894
CtBPC-terminal Binding Protein0.881
eygeyegone0.879
ecdecdysoneless0.871
kluklumpfuss0.870
mammastermind0.864
phlpole hole0.861
Su(H)Suppressor of Hairless0.854
HLHm7E(spl) region transcript m70.848
DrefDNA replication-related element factor0.847
edechinoid0.847
bsblistered0.847
EgfrEpidermal growth factor receptor0.844
dmdiminutive0.823
Rac1CG2248 gene product from transcript CG2248-RA0.814
tgotango0.801
cicubitus interruptus0.799
TolloCG6890 gene product from transcript CG6890-RA0.798
TorTarget of rapamycin0.791
hephemipterous0.787
l(2)37Cblethal (2) 37Cb0.787
CG4699CG4699 gene product from transcript CG4699-RJ0.783
RhebCG1081 gene product from transcript CG1081-RA0.779
opaodd paired0.778
ushu-shaped0.768
slmbsupernumerary limbs0.761
noinoisette0.760
acachaete0.759
Sir2CG5216 gene product from transcript CG5216-RA0.754
Hrb27CHeterogeneous nuclear ribonucleoprotein at 27C0.746
SosSon of sevenless0.740
SerSerrate0.739
Mi-2CG8103 gene product from transcript CG8103-RA0.733
CkIIalphaCasein kinase II alpha subunit0.730
carcarnation0.721
lzlozenge0.719
NrgNeuroglian0.716
grogroucho0.708
atoatonal0.707
domedomeless0.704
CycACyclin A0.704
C15CG7937 gene product from transcript CG7937-RA0.697
ftz-f1ftz transcription factor 10.697
AntpAntennapedia0.691
senssenseless0.688
Bre1CG10542 gene product from transcript CG10542-RA0.682
eyeyeless0.678
ssspineless0.677
mib1mind bomb 10.675
alaristaless0.671
babobaboon0.671
Ulp1CG12359 gene product from transcript CG12359-RA0.670
discodisconnected0.670
apapterous0.669
jingCG9397 gene product from transcript CG9397-RI0.665
snssticks and stones0.665
sizschizo0.664
spispitz0.662
enengrailed0.658
pntpointed0.657
taitaiman0.655
exdextradenticle0.654
SoxNSoxNeuro0.649
emsempty spiracles0.648
HLH54FCG5005 gene product from transcript CG5005-RA0.644
MED15Mediator complex subunit 150.629
rorough0.620
CG11347CG11347 gene product from transcript CG11347-RE0.618
pbproboscipedia0.618
lolalongitudinals lacking0.614
CG10263CG10263 gene product from transcript CG10263-RC0.613
Mekk1CG7717 gene product from transcript CG7717-RB0.613
dncdunce0.612
jebjelly belly0.612
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
pha-4Protein PHA-41.000
egl-18Protein EGL-180.999
elt-6Protein ELT-60.993
nhr-67Protein NHR-670.984
vab-3Protein VAB-30.950
nhr-49Protein NHR-490.926
unc-62Protein UNC-620.883
zip-7Protein ZIP-70.869
pbrm-1Protein PBRM-10.867
egl-44Protein EGL-440.862
pop-1Protein POP-10.842
egl-46Protein EGL-460.822
lin-17Protein LIN-170.781
fkh-2Protein FKH-20.757
hnd-1Protein HND-10.751
lntl-1Protein LNTL-10.731
daf-1Protein DAF-10.721
apr-1Protein APR-10.711
mat-3Protein MAT-30.701
zfp-3Protein ZFP-30.698
egl-13Protein EGL-130.698
daf-3Protein DAF-30.651
rad-26Protein RAD-260.644
pkg-1Protein PKG-10.633
D1081.8Protein D1081.80.629
his-31Protein HIS-310.627
mep-1Protein MEP-10.624
ten-1Protein TEN-10.608
abl-1Protein ABL-10.598
hif-1Protein HIF-10.589
lin-36Protein LIN-360.589
eya-1Protein EYA-10.586
cam-1Protein CAM-10.584
let-60Protein LET-600.580
smp-1Protein SMP-10.571
hlh-1Protein HLH-10.559
hbl-1Protein HBL-10.556
lin-12Protein LIN-120.556
unc-42Protein UNC-420.549
nhr-45Protein NHR-450.546
bar-1Protein BAR-10.533
abi-1Protein ABI-10.515
egl-8Protein EGL-80.512
hlh-2Protein HLH-20.511
unc-73Protein UNC-730.509
K10D6.4Protein K10D6.40.501
ajm-1Protein AJM-10.495
sea-2Protein SEA-20.495
his-64Protein HIS-640.490
lin-35Protein LIN-350.489
mab-31Protein MAB-310.487
his-1Protein HIS-10.485
sel-10Protein SEL-100.474
nhr-34Protein NHR-340.473
ldb-1Protein LDB-10.466
CELE_Y41E3.11Protein Y41E3.110.465
npp-1Protein NPP-10.454
rsp-1Protein RSP-10.452
soc-2Protein SOC-20.452
bet-1Protein BET-10.451
T28F4.1Protein T28F4.10.442
CELE_F47G4.4Protein F47G4.40.438
attf-2Protein ATTF-20.431
flh-2Protein FLH-20.427
Y47D3A.29Protein Y47D3A.290.422
F26B1.2Protein F26B1.20.422
rps-2Protein RPS-20.418
mig-5Protein MIG-50.415
eor-2Protein EOR-20.415
his-5Protein HIS-50.412
ceh-34Protein CEH-340.411
dpy-22Protein DPY-220.411
glp-1Protein GLP-10.410
svh-2Protein SVH-20.410
ceh-16Protein CEH-160.405
daf-14Protein DAF-140.400
hmg-4Protein HMG-40.392
lin-48Protein LIN-480.392
mel-28Protein MEL-280.381
wrm-1Protein WRM-10.381
mab-5Protein MAB-50.378
eef-1A.1Protein EEF-1A.10.375
fntb-1Protein FNTB-10.375
tmc-2Protein TMC-20.374
lsy-22Protein LSY-220.372
F28B3.1Protein F28B3.10.371
lsy-2Protein LSY-20.368
ceh-27Protein CEH-270.367
unc-86Protein UNC-860.355
ceh-36Protein CEH-360.352
ceh-20Protein CEH-200.351
unc-26Protein UNC-260.348
let-19Protein LET-190.346
skp-1Protein SKP-10.344
pmk-1Protein PMK-10.344
pes-1Protein PES-10.343
pry-1Protein PRY-10.341
his-46Protein HIS-460.336
T04C9.1Protein T04C9.10.334
nfyb-1Protein NFYB-10.331
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
flhfloating head0.988
ndr2nodal-related 20.946
chdchordin0.942
hand2heart and neural crest derivatives expressed transcript 20.935
dlcdeltaC0.888
pitx3paired-like homeodomain transcription factor 30.885
tbx1T-box 10.881
hnf1baHNF1 homeobox Ba0.877
dlx2adistal-less homeobox gene 2a0.869
tp53tumor protein p530.830
gli1GLI-Kruppel family member 10.813
notch1anotch homolog 1a0.803
shhasonic hedgehog a0.792
myf5myogenic factor 50.790
nkx2.2aNK2 transcription factor related 2a0.784
runx2brunt-related transcription factor 2b0.779
dlx5adistal-less homeobox gene 5a0.689
lhx5LIM homeobox 50.661
sox1aSRY-box containing gene 1a0.660
lmx1b.1LIM homeobox transcription factor 1, beta 10.659
foxi1forkhead box I10.654
gata3GATA-binding protein 30.646
hoxc4ahomeo box C4a0.638
runx2arunt-related transcription factor 2a0.630
otx2orthodenticle homolog 20.625
nanos3nanos homolog 30.617
tbx20T-box 200.600
pax8paired box gene 80.598
foxa3forkhead box A30.594
osr1odd-skipped related 1 (Drosophila)0.580
barx1BarH-like homeobox 10.574
sox19aSRY-box containing gene 19a0.565
tal1T-cell acute lymphocytic leukemia 10.562
gata5GATA-binding protein 50.555
dusp6dual specificity phosphatase 60.546
rhoabras homolog gene family, member Ab0.536
spry4sprouty (Drosophila) homolog 40.533
eomesaeomesodermin homolog a0.523
spawsouthpaw0.521
bmp4bone morphogenetic protein 40.518
oepone-eyed pinhead0.511
eng2aengrailed 2a0.493
bmp2bbone morphogenetic protein 2b0.491
six1bsine oculis homeobox homolog 1b0.487
nr2e3nuclear receptor subfamily 2, group E, member 30.484
ptf1apancreas specific transcription factor, 1a0.476
irx1biroquois homeobox protein 1, b0.470
wnt5bwingless-type MMTV integration site family, member 5b0.458
atoh1aatonal homolog 1a0.449
lhx1aLIM homeobox 1a0.438
myod1myogenic differentiation 10.437
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.429
gata6GATA-binding protein 60.427
tbx16T-box gene 160.422
fezf2FEZ family zinc finger 20.420
wnt11wingless-type MMTV integration site family, member 110.420
raraaretinoic acid receptor, alpha a0.412
rx3retinal homeobox gene 30.412
six3bsine oculis homeobox homolog 3b0.408
fn1fibronectin 10.391
socs3asuppressor of cytokine signaling 3a0.389
wnt3awingless-type MMTV integration site family, member 3A0.382
junbjun B proto-oncogene0.376
mab21l2mab-21-like 20.373
nrg2aneuregulin 2a0.372
foxa2forkhead box A20.362
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.362
fgfr4fibroblast growth factor receptor 40.360
pcnaproliferating cell nuclear antigen0.358
irx4biroquois homeobox protein 4b0.356
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.353
lft1lefty10.352
crabp2acellular retinoic acid binding protein 2, a0.338
prlprolactin0.332
fibinfin bud initiation factor0.331
ntlano tail a0.329
hoxc6ahomeo box C6a0.318
pax6apaired box gene 6a0.318
fgf4fibroblast growth factor 40.317
igf3insulin-like growth factor 30.315
trim71tripartite motif-containing 710.313
hhexhematopoietically expressed homeobox0.311
neurodneurogenic differentiation0.306
tgfb3transforming growth factor, beta 30.301
isl1islet10.300
nkx2.2bNK2 transcription factor related 2b0.294
gdnfglial cell derived neurotrophic factor0.293
rx2retinal homeobox gene 20.292
pax6bpaired box gene 6b0.287
wnt10bwingless-type MMTV integration site family, member 10b0.285
sox32SRY-box containing gene 320.281
oprd1bopioid receptor, delta 1b0.281
junjun proto-oncogene0.278
bhlhe22basic helix-loop-helix family, member e220.275
mef2dmyocyte enhancer factor 2d0.275
pdlim3bPDZ and LIM domain 3b0.271
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.268
otpborthopedia homolog b0.267
oprm1opioid receptor, mu 10.265
wnt2bawingless-type MMTV integration site family, member 2Ba0.265
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Fgfr1Fibroblast growth factor receptor 10.794
Rararetinoic acid receptor, alpha0.782
Jak2Janus kinase 20.686
Nr4a3nuclear receptor subfamily 4, group A, member 30.667
Junbjun B proto-oncogene0.628
Tgfbr2transforming growth factor, beta receptor II0.607
Ncr1natural cytotoxicity triggering receptor 10.570
Nedd4neural precursor cell expressed, developmentally down-regulated 40.549
Prdm2PR domain containing 2, with ZNF domain0.539
Ptafrplatelet-activating factor receptor0.528
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.524
Jak1Janus kinase 10.499
Notch3Notch homolog 3 (Drosophila)0.487
Itgamintegrin, alpha M0.480
Acvr1activin A receptor, type I0.478
Cd4Cd4 molecule0.473
Ddr1discoidin domain receptor tyrosine kinase 10.468
Egr1early growth response 10.447
Slc8a2solute carrier family 8 (sodium/calcium exchanger), member 20.439
Klf6Kruppel-like factor 60.434
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.434
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.425
JunJun oncogene0.425
FosFBJ osteosarcoma oncogene0.421
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.418
Dusp1dual specificity phosphatase 10.414
Smad7SMAD family member 70.411
Rasa1RAS p21 protein activator (GTPase activating protein) 10.387
Metmet proto-oncogene0.377
Fgfr2fibroblast growth factor receptor 20.377
Ciitaclass II, major histocompatibility complex, transactivator0.376
S100a10S100 calcium binding protein A100.374
Uts2rurotensin 2 receptor0.374
Sox17SRY (sex determining region Y)-box 170.373
Zfp36zinc finger protein 360.372
Nek9NIMA (never in mitosis gene a)- related kinase 90.371
Sirpasignal-regulatory protein alpha0.367
Htr1f5-hydroxytryptamine (serotonin) receptor 1F0.357
Cmklr1chemokine-like receptor 10.355
Igfbp5insulin-like growth factor binding protein 50.346
Mef2dmyocyte enhancer factor 2D0.343
Phf12PHD finger protein 120.338
Nr4a1nuclear receptor subfamily 4, group A, member 10.337
Prph2peripherin 20.336
Cpdcarboxypeptidase D0.335
Irs1insulin receptor substrate 10.329
Slc6a6solute carrier family 6 (neurotransmitter transporter, taurine), member 60.327
Figfc-fos induced growth factor0.324
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.322
Pdynprodynorphin0.319
Slc18a3solute carrier family 18 (vesicular acetylcholine), member 30.318
Tcfe2atranscription factor E2a0.315
Btg2BTG family, member 20.314
Mc4rmelanocortin 4 receptor0.311
Ucnurocortin0.310
Kcnj1potassium inwardly-rectifying channel, subfamily J, member 10.310
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.308
Pja2praja 2, RING-H2 motif containing0.302
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.301
Tcf4transcription factor 40.299
Eif3eeukaryotic translation initiation factor 3, subunit E0.297
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.295
Shox2short stature homeobox 20.294
Thop1thimet oligopeptidase 10.294
Synposynaptopodin0.293
Nrp1neuropilin 10.292
Cd86CD86 molecule0.287
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.282
Rps6ka1ribosomal protein S6 kinase polypeptide 10.280
Smad3SMAD family member 30.277
TekTEK tyrosine kinase, endothelial0.276
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.276
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.275
Errfi1ERBB receptor feedback inhibitor 10.275
Ednrbendothelin receptor type B0.273
Nck1NCK adaptor protein 10.272
Nfibnuclear factor I/B0.271
Bat3HLA-B-associated transcript 30.270
Tcof1Treacher Collins-Franceschetti syndrome 1 homolog (human)0.270
Nr1d2nuclear receptor subfamily 1, group D, member 20.264
Map3k3mitogen activated protein kinase kinase kinase 30.261
Notch2Notch homolog 2 (Drosophila)0.260
Scn4asodium channel, voltage-gated, type IV, alpha subunit0.260
Pdgfbplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.259
Il8rainterleukin 8 receptor, alpha0.258
Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.258
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.257
Adcy4adenylate cyclase 40.255
Arandrogen receptor0.255
Adrb1adrenergic, beta-1-, receptor0.255
Cyp21a1cytochrome P450, family 21, subfamily a, polypeptide 10.254
Ptpn1protein tyrosine phosphatase, non-receptor type 10.254
Phkg1phosphorylase kinase, gamma 10.252
Stat5bsignal transducer and activator of transcription 5B0.250
Klf13Kruppel-like factor 130.250
Zfp91zinc finger protein 910.249
Lphn2latrophilin 20.246
FynFYN oncogene related to SRC, FGR, YES0.246
Umoduromodulin0.244
CrebbpCREB binding protein0.243
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
SIN3Sin3p0.992
GAL11Gal11p0.974
GLN3Gln3p0.959
SWI6Swi6p0.948
MSN2Msn2p0.925
HHT1Hht1p0.920
SNF2Snf2p0.912
YAK1Yak1p0.906
SLT2Slt2p0.905
SNF6Snf6p0.900
HSP82Hsp82p0.899
URE2Ure2p0.895
SPT15Spt15p0.890
TOR1Tor1p0.889
SSN3Ssn3p0.878
GCN5Gcn5p0.873
YAP1Yap1p0.870
RTG3Rtg3p0.869
SSN2Ssn2p0.865
SIN4Sin4p0.861
ADA2Ada2p0.854
SWI1Swi1p0.851
MET4Met4p0.846
ROX3Rox3p0.832
RXT2Rxt2p0.830
SPT8Spt8p0.826
CHD1Chd1p0.822
RGR1Rgr1p0.808
RIM101Rim101p0.800
CCR4Ccr4p0.795
CDC28Cdc28p0.786
CDC6Cdc6p0.786
SRB4Srb4p0.782
MKS1Mks1p0.780
SNF5Snf5p0.763
CYC8Cyc8p0.748
MED1Med1p0.743
RPT6Rpt6p0.736
FKH1Fkh1p0.735
CTI6Cti6p0.724
MIG1Mig1p0.722
RIM15Rim15p0.722
SNF1Snf1p0.717
MCM1Mcm1p0.716
DCP2Dcp2p0.712
KIN28Kin28p0.693
INO4Ino4p0.681
MKK2Mkk2p0.680
RAS2Ras2p0.678
PPH21Pph21p0.676
DOT6Dot6p0.672
MOT2Mot2p0.668
MPT5Mpt5p0.658
NUP157Nup157p0.655
ARG81Arg81p0.643
HAP4Hap4p0.628
YTA7Yta7p0.627
HMO1Hmo1p0.626
SFL1Sfl1p0.623
PGD1Pgd1p0.623
PTC1Ptc1p0.615
CLB1Clb1p0.611
GAL80Gal80p0.603
RPD3Rpd3p0.602
SKN7Skn7p0.599
MOT1Mot1p0.598
STD1Std1p0.597
SNT1Snt1p0.589
MDS3Mds3p0.581
MSN4Msn4p0.573
KSS1Kss1p0.569
AFT1Aft1p0.565
STE20Ste20p0.558
HOG1Hog1p0.557
MUS81Mus81p0.555
NUT2Nut2p0.551
MED2Med2p0.550
RTF1Rtf1p0.542
UTP22Utp22p0.538
NUP84Nup84p0.532
CDC39Cdc39p0.529
RSC4Rsc4p0.527
SRB5Srb5p0.524
MSS11Mss11p0.524
SSN8Ssn8p0.516
CGI121Cgi121p0.512
ESA1Esa1p0.511
RHO1Rho1p0.508
GYL1Gyl1p0.500
SPT7Spt7p0.500
HTB1Htb1p0.498
CPR6Cpr6p0.498
PCC1Pcc1p0.496
MED6Med6p0.493
FYV8Fyv8p0.488
KSP1Ksp1p0.485
RPN10Rpn10p0.474
CAT8Cat8p0.471
MRS6Mrs6p0.471
PHO80Pho80p0.469