The network for 'positive regulation of fibroblast growth factor receptor signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of fibroblast growth factor receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.

NameDescriptionProbabilityFunc Analog Organism
Ext2CG8433 gene product from transcript CG8433-RA0.814
ttvtout-velu0.668
botvbrother of tout-velu0.605
ShcSHC-adaptor protein0.391
wgwingless0.260
sglsugarless0.255
Ras85DRas oncogene at 85D0.189
EgfrEpidermal growth factor receptor0.148
mib1mind bomb 10.087
crbcrumbs0.084
dshdishevelled0.075
dppdecapentaplegic0.072
smosmoothened0.069
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.041
pUf68poly U binding factor 68kD0.039
eyaeyes absent0.038
Vps35Vacuolar protein sorting 350.038
wlswntless0.036
domedomeless0.035
PsnPresenilin0.028
dvedefective proventriculus0.027
SmrSmrter0.026
bazbazooka0.025
EloAElongin A0.023
sflsulfateless0.021
argosCG4531 gene product from transcript CG4531-RA0.021
cicubitus interruptus0.020
ChcClathrin heavy chain0.020
fufused0.019
ash2absent, small, or homeotic discs 20.019
Bre1CG10542 gene product from transcript CG10542-RA0.019
drkdownstream of receptor kinase0.019
araaraucan0.018
WnkCG7177 gene product from transcript CG7177-RA0.016
MadMothers against dpp0.015
sqhspaghetti squash0.015
CG9139CG9139 gene product from transcript CG9139-RA0.015
StamSignal transducing adaptor molecule0.015
l(2)gllethal (2) giant larvae0.014
pntpointed0.014
Mo25CG4083 gene product from transcript CG4083-RA0.014
frcfringe connection0.013
invinvected0.013
arrarrow0.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
wnt10awingless-type MMTV integration site family, member 10a0.695
wnt8bwingless-type MMTV integration site family, member 8b0.650
gli1GLI-Kruppel family member 10.556
tbx1T-box 10.499
lef1lymphocyte enhancer binding factor 10.472
dharmadharma0.439
wnt1wingless-type MMTV integration site family, member 10.420
ptch2patched 20.402
robo3roundabout homolog 30.388
prdm1aPR domain containing 1a, with ZNF domain0.383
ndr2nodal-related 20.357
wnt5bwingless-type MMTV integration site family, member 5b0.355
bmp2abone morphogenetic protein 2a0.346
wnt4awingless-type MMTV integration site family, member 4a0.326
bmp4bone morphogenetic protein 40.262
wnt2wingless-type MMTV integration site family member 20.231
wnt9bwingless-type MMTV integration site family, member 9B0.229
fgf17fibroblast growth factor 170.217
lft1lefty10.203
wnt3wingless-type MMTV integration site family, member 30.183
wnt9awingless-type MMTV integration site family, member 9A0.171
fgf8afibroblast growth factor 8 a0.170
wnt10bwingless-type MMTV integration site family, member 10b0.163
ndr1nodal-related 10.142
fgf3fibroblast growth factor 30.128
wnt7aawingless-type MMTV integration site family, member 7Aa0.127
zfyve26zinc finger, FYVE domain containing 260.127
twist3twist30.123
smad9MAD homolog 9 (Drosophila)0.116
ippkinositol 1,3,4,5,6-pentakisphosphate 2-kinase0.112
osr2odd-skipped related 2 (Drosophila)0.111
smosmoothened homolog (Drosophila)0.109
flhfloating head0.106
map2k4amitogen-activated protein kinase kinase 4a0.104
wnt3awingless-type MMTV integration site family, member 3A0.097
wnt7bbwingless-type MMTV integration site family, member 7Bb0.091
lhx2bLIM homeobox 2b0.090
zic3zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)0.085
hoxd4ahomeo box D4a0.082
shhasonic hedgehog a0.080
fgf4fibroblast growth factor 40.078
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.071
sp8asp8 transcription factor a0.066
pou5f1POU domain, class 5, transcription factor 10.057
dkk1bdickkopf 1b0.055
brd4bromodomain containing 40.052
col11a2collagen type XI alpha-20.052
sec24dSEC24 family, member D (S. cerevisiae)0.050
ephb4beph receptor B4b0.047
wnt16wingless-type MMTV integration site family, member 160.045
mapk3mitogen-activated protein kinase 30.044
wnt7bawingless-type MMTV integration site family, member 7Ba0.044
mpped2metallophosphoesterase domain containing 20.043
msxbmuscle segment homeobox B0.043
hoxa13bhomeo box A13b0.042
ext2exostoses (multiple) 20.040
smad3bMAD, mothers against decapentaplegic homolog 3b (Drosophila)0.038
zbtb4zinc finger and BTB domain containing 40.037
gro2groucho 20.037
sox32SRY-box containing gene 320.037
ihhaIndian hedgehog homolog a0.036
axin1axin 10.036
uxs1UDP-glucuronic acid decarboxylase 10.036
ptch1patched 10.035
plcb3phospholipase C, beta 3 (phosphatidylinositol-specific)0.034
bmp2bbone morphogenetic protein 2b0.034
amotl2aangiomotin like 2a0.033
mapk1mitogen-activated protein kinase 10.033
gngt2bguanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b0.032
frem1aFras1 related extracellular matrix 1a0.032
grem1agremlin 1 homolog a, cysteine knot superfamily (Xenopus laevis)0.031
il17rdinterleukin 17 receptor D0.031
zgc:158603zgc:1586030.030
sall4sal-like 4 (Drosophila)0.030
hmx1H6 homeo box 10.029
bmp1abone morphogenetic protein 1a0.027
ventventral expressed homeobox0.027
extl3exostoses (multiple)-like 30.027
sfrp1asecreted frizzled-related protein 1a0.026
hoxc1ahomeo box C1a0.026
pcdh8protocadherin 80.025
sox11bSRY-box containing gene 11b0.025
pdlim7PDZ and LIM domain 70.024
znf711zinc finger protein 7110.024
jag2jagged 20.024
bmpr1aabone morphogenetic protein receptor, type 1aa0.024
frem2aFras1 related extracellular matrix protein 2a0.024
msxdmuscle segment homeobox D0.023
gli2bGLI-Kruppel family member GLI2b0.023
frzbfrizzled-related protein0.022
wnt2bbwingless-type MMTV integration site family, member 2Bb0.022
runx2brunt-related transcription factor 2b0.022
rarabretinoic acid receptor, alpha b0.022
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.021
gscgoosecoid0.020
sult1st4sulfotransferase family 1, cytosolic sulfotransferase 40.020
mapk15mitogen-activated protein kinase 150.019
spry4sprouty (Drosophila) homolog 40.019
rspo3R-spondin 3 homolog (Xenopus laevis)0.018
admpanti-dorsalizing morphogenic protein0.018
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
STAMBPSTAM binding protein0.992
STAMsignal transducing adaptor molecule (SH3 domain and ITAM motif) 10.545
HDAC7histone deacetylase 70.526
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.254
TCF4transcription factor 40.190
RNF11ring finger protein 110.175
SNRNP70small nuclear ribonucleoprotein 70kDa (U1)0.175
TSG101tumor susceptibility gene 1010.113
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.110
CHMP1Bchromatin modifying protein 1B0.109
RRBP1ribosome binding protein 1 homolog 180kDa (dog)0.087
IFNAR2interferon (alpha, beta and omega) receptor 20.084
ACTN4actinin, alpha 40.081
HGShepatocyte growth factor-regulated tyrosine kinase substrate0.064
GORASP1golgi reassembly stacking protein 1, 65kDa0.044
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.043
VPS24vacuolar protein sorting 24 homolog (S. cerevisiae)0.042
PDGFCplatelet derived growth factor C0.041
CAPZA2capping protein (actin filament) muscle Z-line, alpha 20.039
STAM2signal transducing adaptor molecule (SH3 domain and ITAM motif) 20.031
APCadenomatous polyposis coli0.025
PDGFAplatelet-derived growth factor alpha polypeptide0.025
RXRAretinoid X receptor, alpha0.024
TNIP2TNFAIP3 interacting protein 20.024
GGA3golgi-associated, gamma adaptin ear containing, ARF binding protein 30.024
VPS4Bvacuolar protein sorting 4 homolog B (S. cerevisiae)0.023
JAK1Janus kinase 10.022
GLIS2GLIS family zinc finger 20.022
PDLIM7PDZ and LIM domain 7 (enigma)0.022
MDFIMyoD family inhibitor0.021
GGA1golgi-associated, gamma adaptin ear containing, ARF binding protein 10.020
NEDD4neural precursor cell expressed, developmentally down-regulated 40.019
UBQLN1ubiquilin 10.019
EHMT2euchromatic histone-lysine N-methyltransferase 20.019
SEC24CSEC24 family, member C (S. cerevisiae)0.018
UBA1ubiquitin-like modifier activating enzyme 10.017
EXOC7exocyst complex component 70.016
GDI1GDP dissociation inhibitor 10.016
COL5A1collagen, type V, alpha 10.016
ZRANB1zinc finger, RAN-binding domain containing 10.015
TOM1target of myb1 (chicken)0.015
KLF5Kruppel-like factor 5 (intestinal)0.015
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.014
DAZAP2DAZ associated protein 20.014
MORF4L1mortality factor 4 like 10.013
GAKcyclin G associated kinase0.013
COL6A1collagen, type VI, alpha 10.013
MT2Ametallothionein 2A0.012
UBQLN2ubiquilin 20.012
CHMP5chromatin modifying protein 50.012
NUDT3nudix (nucleoside diphosphate linked moiety X)-type motif 30.012
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.011
MT1Hmetallothionein 1H0.011
AXIN1axin 10.011
EXOC8exocyst complex component 80.011
NCOA1nuclear receptor coactivator 10.010
NPLOC4nuclear protein localization 4 homolog (S. cerevisiae)0.010
PSEN1presenilin 10.010
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.010
SIRT7sirtuin 70.010
MTPNmyotrophin0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 20.964
Shhsonic hedgehog0.912
Nos3nitric oxide synthase 3, endothelial cell0.845
Gli3GLI-Kruppel family member GLI30.791
Flt4FMS-like tyrosine kinase 40.638
Nr0b1nuclear receptor subfamily 0, group B, member 10.455
Ptenphosphatase and tensin homolog0.427
Notch2Notch gene homolog 2 (Drosophila)0.385
Usp8ubiquitin specific peptidase 80.352
Bmp4bone morphogenetic protein 40.352
Itga3integrin alpha 30.344
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.340
Kdrkinase insert domain protein receptor0.323
Lama5laminin, alpha 50.322
Pou5f1POU domain, class 5, transcription factor 10.292
Sox9SRY-box containing gene 90.266
Sall1sal-like 1 (Drosophila)0.233
Gaaglucosidase, alpha, acid0.230
Rxraretinoid X receptor alpha0.210
Tcfcp2l1transcription factor CP2-like 10.198
Fgf8fibroblast growth factor 80.179
NanogNanog homeobox0.169
Hbegfheparin-binding EGF-like growth factor0.151
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.150
Ctnnb1catenin (cadherin associated protein), beta 10.148
Apcadenomatosis polyposis coli0.137
Hes1hairy and enhancer of split 1 (Drosophila)0.136
Samd4bsterile alpha motif domain containing 4B0.135
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.129
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.128
Itgb1integrin beta 1 (fibronectin receptor beta)0.126
Esrrbestrogen related receptor, beta0.121
Otx2orthodenticle homolog 2 (Drosophila)0.119
Tbx3T-box 30.116
Sox13SRY-box containing gene 130.115
Sh3bgrlSH3-binding domain glutamic acid-rich protein like0.114
Stam2signal transducing adaptor molecule (SH3 domain and ITAM motif) 20.114
Lrp6low density lipoprotein receptor-related protein 60.110
Pkd1polycystic kidney disease 1 homolog0.103
Arandrogen receptor0.099
Trp53transformation related protein 530.097
Flt1FMS-like tyrosine kinase 10.096
Ptpn11protein tyrosine phosphatase, non-receptor type 110.095
Efnb1ephrin B10.094
Fbrsfibrosin0.092
Tcf21transcription factor 210.089
Notch1Notch gene homolog 1 (Drosophila)0.088
Aplnapelin0.080
Serinc1serine incorporator 10.079
Sox7SRY-box containing gene 70.075
Ptmsparathymosin0.074
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.071
Ror2receptor tyrosine kinase-like orphan receptor 20.068
Spry4sprouty homolog 4 (Drosophila)0.068
Wt1Wilms tumor 1 homolog0.067
Fam83hfamily with sequence similarity 83, member H0.067
Wnt5awingless-related MMTV integration site 5A0.066
Plxnd1plexin D10.063
Itfg1integrin alpha FG-GAP repeat containing 10.062
Ptpn14protein tyrosine phosphatase, non-receptor type 140.062
Gng12guanine nucleotide binding protein (G protein), gamma 120.060
Vhlvon Hippel-Lindau tumor suppressor0.059
Smpd3sphingomyelin phosphodiesterase 3, neutral0.058
Fstl3follistatin-like 30.057
Tsc2tuberous sclerosis 20.057
Wbp2WW domain binding protein 20.057
Pitx2paired-like homeodomain transcription factor 20.056
Sfnstratifin0.056
Epn1epsin 10.055
Fgf9fibroblast growth factor 90.054
Foxa2forkhead box A20.053
Ndfip1Nedd4 family interacting protein 10.053
Gata6GATA binding protein 60.053
Col1a1collagen, type I, alpha 10.053
Vegfavascular endothelial growth factor A0.053
Tmem30atransmembrane protein 30A0.052
Epas1endothelial PAS domain protein 10.051
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.051
Abl1c-abl oncogene 1, non-receptor tyrosine kinase0.051
Engendoglin0.051
Col4a3collagen, type IV, alpha 30.051
Nacc1nucleus accumbens associated 1, BEN and BTB (POZ) domain containing0.049
Rab5aRAB5A, member RAS oncogene family0.049
Hoxd11homeobox D110.047
Sox4SRY-box containing gene 40.046
Nrp1neuropilin 10.046
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.046
Smtnsmoothelin0.045
Rb1retinoblastoma 10.045
Stk40serine/threonine kinase 400.045
Nr3c1nuclear receptor subfamily 3, group C, member 10.045
Hspg2perlecan (heparan sulfate proteoglycan 2)0.044
Egln1EGL nine homolog 1 (C. elegans)0.044
Fgfr3fibroblast growth factor receptor 30.043
Etl4enhancer trap locus 40.043
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.042
Cdk16cyclin-dependent kinase 160.041
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.040
Epha2Eph receptor A20.040
Sox18SRY-box containing gene 180.040
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism