The network for 'nuclear transcribed mrna catabolic process deadenylation dependent decay' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

nuclear transcribed mrna catabolic process deadenylation dependent decay

A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.

NameDescriptionProbabilityFunc Analog Organism
DlicDynein light intermediate chain0.511
traltrailer hitch0.486
cactcactus0.420
rinrasputin0.379
CG4699CG4699 gene product from transcript CG4699-RJ0.331
aubaubergine0.222
cupCG11181 gene product from transcript CG11181-RB0.176
RpL22Ribosomal protein L220.096
Tsp96FTetraspanin 96F0.089
blotbloated tubules0.082
Mtr3CG8025 gene product from transcript CG8025-RA0.082
l(1)G0289lethal (1) G02890.074
Rab8Rab-protein 80.074
Cul-4Cullin-40.071
wispwispy0.063
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.061
piwiCG6122 gene product from transcript CG6122-RA0.059
CG10289CG10289 gene product from transcript CG10289-RA0.052
PknProtein kinase related to protein kinase N0.047
CragCalmodulin-binding protein related to a Rab3 GDP/GTP exchange protein0.046
Hrb27CHeterogeneous nuclear ribonucleoprotein at 27C0.044
mus309mutagen-sensitive 3090.040
aretarrest0.039
Map205Microtubule-associated protein 2050.037
Atx2Ataxin-20.036
Pk61CProtein kinase 61C0.035
Dcp2Decapping protein 20.035
CG17266CG17266 gene product from transcript CG17266-RA0.034
rhirhino0.034
twinCG31137 gene product from transcript CG31137-RB0.034
CG7339CG7339 gene product from transcript CG7339-RA0.033
TrnTransportin0.032
stwlstonewall0.030
mavmaverick0.030
defldeflated0.030
bambag of marbles0.029
spn-Espindle E0.029
UBL3CG9038 gene product from transcript CG9038-RC0.029
belbelle0.028
DNApol-alpha50DNA polymerase alpha 50kD0.028
RhoGAP92BCG4755 gene product from transcript CG4755-RA0.027
RpS26Ribosomal protein S260.027
sxcsuper sex combs0.026
CG2100CG2100 gene product from transcript CG2100-RB0.026
PenPendulin0.026
CG14544CG14544 gene product from transcript CG14544-RA0.026
Nipped-BCG17704 gene product from transcript CG17704-RI0.024
CG8443CG8443 gene product from transcript CG8443-RA0.024
dgt4dim gamma-tubulin 40.024
RpL35Ribosomal protein L350.021
swshort wing0.018
CG10722CG10722 gene product from transcript CG10722-RA0.018
deldeadlock0.018
maelmaelstrom0.017
pgant3polypeptide GalNAc transferase 30.017
Adf1Adh transcription factor 10.016
eIF4Geukaryotic translation initiation factor 4G0.016
CG3434CG3434 gene product from transcript CG3434-RA0.016
zpgzero population growth0.016
egeagle0.015
slouslouch0.015
dapdacapo0.015
Rpn11CG18174 gene product from transcript CG18174-RA0.015
koiklaroid0.014
RPA2Replication protein A20.014
Ard1Arrest defective 10.014
cuffcutoff0.014
CG13624CG13624 gene product from transcript CG13624-RD0.014
Smg6CG6369 gene product from transcript CG6369-RA0.014
armiarmitage0.013
CG9304CG9304 gene product from transcript CG9304-RA0.013
Gbeta13FG protein beta-subunit 13F0.013
eIF-5ACG3186 gene product from transcript CG3186-RA0.013
fs(1)Ybfemale sterile (1) Yb0.013
CycGCyclin G0.013
Src64BSrc oncogene at 64B0.012
Dbp73DDead box protein 73D0.012
CG12016CG12016 gene product from transcript CG12016-RA0.012
ctaconcertina0.012
tostosca0.012
MED26Mediator complex subunit 260.012
spn-Dspindle D0.011
CG33095CG33095 gene product from transcript CG33095-RB0.011
vasvasa0.011
CG8414CG8414 gene product from transcript CG8414-RA0.011
MtlMig-2-like0.011
mus301mutagen-sensitive 3010.010
CCKLR-17D1CCK-like receptor at 17D10.010
GATAdCG5034 gene product from transcript CG5034-RA0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PABPC1poly(A) binding protein, cytoplasmic 11.000
TOB1transducer of ERBB2, 11.000
TNRC6Atrinucleotide repeat containing 6A0.999
PAN3PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)0.992
CNOT1CCR4-NOT transcription complex, subunit 10.987
TNRC6Ctrinucleotide repeat containing 6C0.978
DCP1ADCP1 decapping enzyme homolog A (S. cerevisiae)0.974
TNRC6Btrinucleotide repeat containing 6B0.873
CNOT7CCR4-NOT transcription complex, subunit 70.765
EXOSC7exosome component 70.743
EIF2C1eukaryotic translation initiation factor 2C, 10.734
CNOT8CCR4-NOT transcription complex, subunit 80.705
CNOT2CCR4-NOT transcription complex, subunit 20.686
BTG1B-cell translocation gene 1, anti-proliferative0.681
PAIP2poly(A) binding protein interacting protein 20.575
PCBP2poly(rC) binding protein 20.573
EXOSC10exosome component 100.412
CNOT6LCCR4-NOT transcription complex, subunit 6-like0.358
EIF4G1eukaryotic translation initiation factor 4 gamma, 10.347
EIF2C2eukaryotic translation initiation factor 2C, 20.316
CNOT6CCR4-NOT transcription complex, subunit 60.290
GSPT1G1 to S phase transition 10.272
YBX1Y box binding protein 10.211
EXOSC3exosome component 30.172
NOXA1NADPH oxidase activator 10.169
EIF2C4eukaryotic translation initiation factor 2C, 40.165
MAPKAPK2mitogen-activated protein kinase-activated protein kinase 20.161
PCBP1poly(rC) binding protein 10.150
BTG2BTG family, member 20.119
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.091
DICER1dicer 1, ribonuclease type III0.091
EIF4G3eukaryotic translation initiation factor 4 gamma, 30.085
EXOSC2exosome component 20.082
CEBPDCCAAT/enhancer binding protein (C/EBP), delta0.077
EXOSC1exosome component 10.074
SMG1SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)0.055
HNRNPDheterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)0.054
PRKCZprotein kinase C, zeta0.050
PABPC3poly(A) binding protein, cytoplasmic 30.049
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.044
EXOSC4exosome component 40.044
EIF2C3eukaryotic translation initiation factor 2C, 30.039
CARD11caspase recruitment domain family, member 110.038
KLF4Kruppel-like factor 4 (gut)0.036
ATXN2ataxin 20.033
POLR2Epolymerase (RNA) II (DNA directed) polypeptide E, 25kDa0.032
LSM3LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.029
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.027
DIS3LDIS3 mitotic control homolog (S. cerevisiae)-like0.026
PAIP1poly(A) binding protein interacting protein 10.025
IER2immediate early response 20.023
CNOT10CCR4-NOT transcription complex, subunit 100.020
PRKCBprotein kinase C, beta0.019
STAU1staufen, RNA binding protein, homolog 1 (Drosophila)0.018
GSPT2G1 to S phase transition 20.018
TSC22D1TSC22 domain family, member 10.017
PICK1protein interacting with PRKCA 10.017
CPEB3cytoplasmic polyadenylation element binding protein 30.017
SBF1SET binding factor 10.016
CPEB4cytoplasmic polyadenylation element binding protein 40.016
DUSP1dual specificity phosphatase 10.015
CDCP1CUB domain containing protein 10.014
SH3RF1SH3 domain containing ring finger 10.014
PMS2PMS2 postmeiotic segregation increased 2 (S. cerevisiae)0.014
NR4A2nuclear receptor subfamily 4, group A, member 20.014
TOB2transducer of ERBB2, 20.013
UPF2UPF2 regulator of nonsense transcripts homolog (yeast)0.012
EXOSC5exosome component 50.012
PNRC1proline-rich nuclear receptor coactivator 10.012
CNOT3CCR4-NOT transcription complex, subunit 30.012
EIF4Beukaryotic translation initiation factor 4B0.011
BARD1BRCA1 associated RING domain 10.011
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Eif2c2eukaryotic translation initiation factor 2C, 21.000
Ddx6DEAD (Asp-Glu-Ala-Asp) box polypeptide 60.984
Tnrc6btrinucleotide repeat containing 6b0.744
Mll3myeloid/lymphoid or mixed-lineage leukemia 30.667
JunbJun-B oncogene0.634
FosFBJ osteosarcoma oncogene0.598
Bptfbromodomain PHD finger transcription factor0.524
Dusp1dual specificity phosphatase 10.520
Neurl1aneuralized homolog 1A (Drosophila)0.343
Egr1early growth response 10.279
Zfp36zinc finger protein 360.219
Gsk3bglycogen synthase kinase 3 beta0.214
Trim32tripartite motif-containing 320.204
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.181
Brd4bromodomain containing 40.173
Btg2B-cell translocation gene 2, anti-proliferative0.172
Btg1B-cell translocation gene 1, anti-proliferative0.170
Cnot6CCR4-NOT transcription complex, subunit 60.145
Sp1trans-acting transcription factor 10.123
Nr4a1nuclear receptor subfamily 4, group A, member 10.109
Actn2actinin alpha 20.108
Pard3par-3 (partitioning defective 3) homolog (C. elegans)0.104
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.096
Wnk1WNK lysine deficient protein kinase 10.086
Caprin1cell cycle associated protein 10.083
Ier2immediate early response 20.083
Akap9A kinase (PRKA) anchor protein (yotiao) 90.082
Igf1rinsulin-like growth factor I receptor0.081
Nudcd2NudC domain containing 20.079
Irs2insulin receptor substrate 20.077
Mll5myeloid/lymphoid or mixed-lineage leukemia 50.072
Klf6Kruppel-like factor 60.071
Rcor1REST corepressor 10.068
JunJun oncogene0.067
Ldb3LIM domain binding 30.065
Trraptransformation/transcription domain-associated protein0.060
Mll1myeloid/lymphoid or mixed-lineage leukemia 10.059
Ankhd1ankyrin repeat and KH domain containing 10.056
Pum1pumilio 1 (Drosophila)0.054
Tnrc6ctrinucleotide repeat containing 6C0.052
Pabpc1poly(A) binding protein, cytoplasmic 10.047
Tnfaip3tumor necrosis factor, alpha-induced protein 30.047
Brd2bromodomain containing 20.045
Rc3h1RING CCCH (C3H) domains 10.044
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.043
Vegfavascular endothelial growth factor A0.042
Akt2thymoma viral proto-oncogene 20.042
Nupl1nucleoporin like 10.038
Celf1CUGBP, Elav-like family member 10.038
Cd28CD28 antigen0.038
Csnk2a1casein kinase 2, alpha 1 polypeptide0.037
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.037
Nfatc3nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 30.037
Arid1aAT rich interactive domain 1A (SWI-like)0.036
Gm2223predicted pseudogene 22230.035
Rasal1RAS protein activator like 1 (GAP1 like)0.034
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.034
Kpnb1karyopherin (importin) beta 10.034
Cnot7CCR4-NOT transcription complex, subunit 70.034
Rfx7regulatory factor X, 70.033
Ncoa1nuclear receptor coactivator 10.033
Smad1MAD homolog 1 (Drosophila)0.033
Mafkv-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)0.033
Map3k1mitogen-activated protein kinase kinase kinase 10.032
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.031
Klf7Kruppel-like factor 7 (ubiquitous)0.030
Vhlvon Hippel-Lindau tumor suppressor0.028
Irf2bp2interferon regulatory factor 2 binding protein 20.028
Atf3activating transcription factor 30.027
Purbpurine rich element binding protein B0.027
Ep300E1A binding protein p3000.027
Arid2AT rich interactive domain 2 (ARID, RFX-like)0.027
Akt1thymoma viral proto-oncogene 10.027
Tnrc6atrinucleotide repeat containing 6a0.026
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.026
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.025
Rhogras homolog gene family, member G0.025
Chd4chromodomain helicase DNA binding protein 40.025
Xpotexportin, tRNA (nuclear export receptor for tRNAs)0.024
D19Wsu162eDNA segment, Chr 19, Wayne State University 162, expressed0.024
Dyrk1adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a0.022
Smad4MAD homolog 4 (Drosophila)0.022
Maelmaelstrom homolog (Drosophila)0.022
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.022
Pknox1Pbx/knotted 1 homeobox0.022
Nanos2nanos homolog 2 (Drosophila)0.021
Man1a2mannosidase, alpha, class 1A, member 20.021
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.021
Ehmt2euchromatic histone lysine N-methyltransferase 20.020
Taok1TAO kinase 10.020
Bcl2B-cell leukemia/lymphoma 20.020
Klf3Kruppel-like factor 3 (basic)0.020
Zmym5zinc finger, MYM-type 50.020
Wdr36WD repeat domain 360.019
Wdr77WD repeat domain 770.019
Kctd20potassium channel tetramerisation domain containing 200.019
Tnfrsf13btumor necrosis factor receptor superfamily, member 13b0.019
Map3k5mitogen-activated protein kinase kinase kinase 50.019
Gspt1G1 to S phase transition 10.019
Chd1lchromodomain helicase DNA binding protein 1-like0.018
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
POP2Pop2p0.992
CAF40Caf40p0.986
DHH1Dhh1p0.944
DEF1Def1p0.930
SKI7Ski7p0.721
MTR3Mtr3p0.721
DCP2Dcp2p0.657
CDC39Cdc39p0.536
PAT1Pat1p0.526
RRP46Rrp46p0.510
SKI3Ski3p0.436
DCP1Dcp1p0.403
LSM2Lsm2p0.393
PBY1Pby1p0.381
EDC3Edc3p0.362
NOT3Not3p0.353
SKI2Ski2p0.325
CSL4Csl4p0.323
PAN3Pan3p0.274
SKI8Ski8p0.268
PUB1Pub1p0.252
TIF4632Tif4632p0.225
MOT2Mot2p0.198
RPB7Rpb7p0.194
NAM7Nam7p0.181
NMD2Nmd2p0.173
LSM4Lsm4p0.164
KEM1Kem1p0.161
GBP2Gbp2p0.158
PBP1Pbp1p0.144
SKI6Ski6p0.136
CDC36Cdc36p0.120
DNM1Dnm1p0.101
MLH2Mlh2p0.100
RPO21Rpo21p0.098
UBP1Ubp1p0.098
MEX67Mex67p0.092
RRP45Rrp45p0.092
UPF3Upf3p0.090
MPT5Mpt5p0.088
RRP40Rrp40p0.086
YTA6Yta6p0.084
HOS2Hos2p0.083
MSH3Msh3p0.081
LSM1Lsm1p0.081
RRP43Rrp43p0.076
CCR4Ccr4p0.073
YMR086Whypothetical protein0.073
CTR86Ctr86p0.069
DIS3Dis3p0.069
RPO26Rpo26p0.067
SCD6Scd6p0.066
RRP6Rrp6p0.061
NGR1Ngr1p0.060
RFU1Rfu1p0.060
YGL101Whypothetical protein0.059
AIM3Aim3p0.059
RPS10BRps10bp0.057
PZF1Pzf1p0.056
TFG2Tfg2p0.055
ZRG8Zrg8p0.054
CAF130Caf130p0.049
TIM44Tim44p0.049
THP2Thp2p0.049
SOK1Sok1p0.048
DAL81Dal81p0.047
HEM3Hem3p0.046
HBT1Hbt1p0.046
URA3Ura3p0.046
KEI1Kei1p0.045
YBL029Whypothetical protein0.044
SMY2Smy2p0.044
CCH1Cch1p0.044
YJL107Chypothetical protein0.044
YLR162Whypothetical protein0.044
PAM1Pam1p0.043
GPH1Gph1p0.043
DCS2Dcs2p0.043
YLR297Whypothetical protein0.042
PMP2Pmp2p0.042
HER1Her1p0.042
CBP1Cbp1p0.041
PRS2Prs2p0.041
YLR363W-Ahypothetical protein0.041
YLR264C-Ahypothetical protein0.040
GPD2Gpd2p0.039
YBR016Whypothetical protein0.039
CTF13Ctf13p0.039
EBS1Ebs1p0.039
SRD1Srd1p0.038
NST1Nst1p0.038
YBL081Whypothetical protein0.037
RRP42Rrp42p0.037
CLU1Clu1p0.036
URB2Urb2p0.036
SUP35Sup35p0.036
ARG8Arg8p0.036
YGR169C-Ahypothetical protein0.036
MSH4Msh4p0.036
PAM18Pam18p0.036