IMP
Process View
The network for 'cellular response to sterol depletion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
cellular response to sterol depletion
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| egg | eggless | 0.372 | |
| rin | rasputin | 0.181 | |
| mael | maelstrom | 0.105 | |
| caz | cabeza | 0.090 | |
| Rel | Relish | 0.078 | |
| th | thread | 0.071 | |
| desat1 | CG5887 gene product from transcript CG5887-RA | 0.066 | |
| Dcp-1 | Death caspase-1 | 0.065 | |
| BG4 | CG12297 gene product from transcript CG12297-RA | 0.060 | |
| dm | diminutive | 0.059 | |
| CG6751 | CG6751 gene product from transcript CG6751-RA | 0.056 | |
| HmgD | High mobility group protein D | 0.051 | |
| imd | immune deficiency | 0.045 | |
| Rbf | Retinoblastoma-family protein | 0.043 | |
| Lk6 | CG17342 gene product from transcript CG17342-RA | 0.043 | |
| Eip63E | Ecdysone-induced protein 63E | 0.041 | |
| Nc | Nedd2-like caspase | 0.039 | |
| Eps-15 | Epidermal growth factor receptor pathway substrate clone 15 | 0.038 | |
| CG6854 | CG6854 gene product from transcript CG6854-RC | 0.038 | |
| Pez | CG9493 gene product from transcript CG9493-RA | 0.038 | |
| lmg | lemming | 0.038 | |
| pUf68 | poly U binding factor 68kD | 0.037 | |
| opa1-like | optic atrophy 1-like | 0.035 | |
| CG8443 | CG8443 gene product from transcript CG8443-RA | 0.035 | |
| Letm1 | CG4589 gene product from transcript CG4589-RB | 0.032 | |
| cpa | capping protein alpha | 0.031 | |
| CG5854 | CG5854 gene product from transcript CG5854-RA | 0.031 | |
| dup | double parked | 0.026 | |
| MESR6 | Misexpression suppressor of ras 6 | 0.025 | |
| ras | raspberry | 0.025 | |
| Ark | Apaf-1-related-killer | 0.025 | |
| Top2 | Topoisomerase 2 | 0.024 | |
| pzg | putzig | 0.023 | |
| Rala | Ras-related protein | 0.023 | |
| Top1 | Topoisomerase 1 | 0.021 | |
| path | pathetic | 0.021 | |
| pex16 | peroxin 16 | 0.021 | |
| p53 | CG33336 gene product from transcript CG33336-RB | 0.021 | |
| Tom34 | Translocase of outer membrane 34 | 0.020 | |
| Ptp61F | Protein tyrosine phosphatase 61F | 0.019 | |
| CG32418 | CG32418 gene product from transcript CG32418-RA | 0.019 | |
| Crag | Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein | 0.019 | |
| ird5 | immune response deficient 5 | 0.019 | |
| CG4287 | CG4287 gene product from transcript CG4287-RB | 0.017 | |
| CG5726 | CG5726 gene product from transcript CG5726-RA | 0.017 | |
| Pngl | PNGase-like | 0.017 | |
| Dlic | Dynein light intermediate chain | 0.017 | |
| DNApol-alpha60 | DNA polymerase alpha 60kD | 0.017 | |
| Lsd-2 | Lipid storage droplet-2 | 0.016 | |
| Unc-76 | CG3981 gene product from transcript CG3981-RB | 0.015 | |
| hfw | halfway | 0.015 | |
| tsr | twinstar | 0.015 | |
| scny | scrawny | 0.015 | |
| uex | unextended | 0.014 | |
| Kap3 | Kinesin associated protein 3 | 0.014 | |
| CG5931 | CG5931 gene product from transcript CG5931-RA | 0.014 | |
| Ho | Heme oxygenase | 0.014 | |
| D1 | D1 chromosomal protein | 0.014 | |
| Mpk2 | CG5475 gene product from transcript CG5475-RB | 0.014 | |
| Deaf1 | Deformed epidermal autoregulatory factor-1 | 0.014 | |
| Lac | Lachesin | 0.013 | |
| sw | short wing | 0.013 | |
| X11L | CG5675 gene product from transcript CG5675-RB | 0.013 | |
| GstS1 | Glutathione S transferase S1 | 0.013 | |
| Pcaf | CG4107 gene product from transcript CG4107-RA | 0.013 | |
| Toll-7 | CG8595 gene product from transcript CG8595-RA | 0.013 | |
| Pabp2 | CG2163 gene product from transcript CG2163-RA | 0.012 | |
| Atg7 | Autophagy-specific gene 7 | 0.012 | |
| l(1)G0469 | lethal (1) G0469 | 0.012 | |
| CG5794 | CG5794 gene product from transcript CG5794-RB | 0.012 | |
| pex1 | peroxin 1 | 0.012 | |
| Nup153 | Nucleoporin 153 | 0.012 | |
| l(2)03659 | lethal (2) 03659 | 0.012 | |
| Marf | Mitochondrial assembly regulatory factor | 0.011 | |
| sqd | squid | 0.011 | |
| Gem3 | Gemin3 | 0.011 | |
| Hrb87F | Heterogeneous nuclear ribonucleoprotein at 87F | 0.011 | |
| Hsc70-3 | Heat shock protein cognate 3 | 0.011 | |
| Uch-L3 | Ubiquitin C-terminal hydrolase | 0.011 | |
| Gs1 | Glutamine synthetase 1 | 0.011 | |
| Sgt1 | CG9617 gene product from transcript CG9617-RA | 0.011 | |
| Usp7 | ubiquitin-specific protease 7 | 0.010 | |
| p38b | CG7393 gene product from transcript CG7393-RA | 0.010 | |
| Sh3beta | CG8582 gene product from transcript CG8582-RD | 0.010 | |
| Papss | PAPS synthetase | 0.010 | |
| CG17746 | CG17746 gene product from transcript CG17746-RA | 0.010 |
Loading network...
Homo sapiens| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.118 | |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.043 | |
| SC4MOL | sterol-C4-methyl oxidase-like | 0.026 | |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.025 | |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.021 | |
| CUL1 | cullin 1 | 0.017 | |
| CCDC6 | coiled-coil domain containing 6 | 0.014 | |
| MMS22L | MMS22-like, DNA repair protein | 0.013 | |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.011 | |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.010 |
Loading network...
Mus musculus| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Lmnb1 | lamin B1 | 0.489 | |
| Lmnb2 | lamin B2 | 0.444 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.387 | |
| Trp53 | transformation related protein 53 | 0.222 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.143 | |
| Fbn1 | fibrillin 1 | 0.126 | |
| Akt1 | thymoma viral proto-oncogene 1 | 0.118 | |
| Sh3pxd2b | SH3 and PX domains 2B | 0.096 | |
| Plec | plectin | 0.091 | |
| Smn1 | survival motor neuron 1 | 0.085 | |
| Gja1 | gap junction protein, alpha 1 | 0.077 | |
| Gtf2ird1 | general transcription factor II I repeat domain-containing 1 | 0.065 | |
| 2310046A06Rik | RIKEN cDNA 2310046A06 gene | 0.050 | |
| Egfr | epidermal growth factor receptor | 0.038 | |
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.037 | |
| Plk1 | polo-like kinase 1 (Drosophila) | 0.034 | |
| Fubp3 | far upstream element (FUSE) binding protein 3 | 0.034 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.034 | |
| Scd1 | stearoyl-Coenzyme A desaturase 1 | 0.032 | |
| Pten | phosphatase and tensin homolog | 0.032 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.028 | |
| Ptk2 | PTK2 protein tyrosine kinase 2 | 0.027 | |
| Dmd | dystrophin, muscular dystrophy | 0.026 | |
| Col1a1 | collagen, type I, alpha 1 | 0.025 | |
| Vegfa | vascular endothelial growth factor A | 0.023 | |
| Cnbp | cellular nucleic acid binding protein | 0.023 | |
| Mcm3 | minichromosome maintenance deficient 3 (S. cerevisiae) | 0.021 | |
| Ank | progressive ankylosis | 0.020 | |
| 2610044O15Rik | RIKEN cDNA 2610044O15 gene | 0.020 | |
| Ik | IK cytokine | 0.020 | |
| Nsa2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | 0.019 | |
| Mfn2 | mitofusin 2 | 0.019 | |
| Sfn | stratifin | 0.019 | |
| Prkce | protein kinase C, epsilon | 0.018 | |
| Atp2a2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.018 | |
| Rcc1 | regulator of chromosome condensation 1 | 0.017 | |
| Supv3l1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.017 | |
| Smad4 | MAD homolog 4 (Drosophila) | 0.017 | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.017 | |
| Paics | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase | 0.016 | |
| Bscl2 | Bernardinelli-Seip congenital lipodystrophy 2 homolog (human) | 0.015 | |
| Zfand1 | zinc finger, AN1-type domain 1 | 0.015 | |
| E2f1 | E2F transcription factor 1 | 0.015 | |
| Dram2 | VDNA-damage regulated autophagy modulator 2 | 0.015 | |
| Ckap4 | cytoskeleton-associated protein 4 | 0.015 | |
| Dynlt3 | dynein light chain Tctex-type 3 | 0.014 | |
| Cav1 | caveolin 1, caveolae protein | 0.014 | |
| Kif2c | kinesin family member 2C | 0.013 | |
| Zbtb45 | zinc finger and BTB domain containing 45 | 0.013 | |
| Lmna | lamin A | 0.013 | |
| Dhcr24 | 24-dehydrocholesterol reductase | 0.013 | |
| Aurka | aurora kinase A | 0.013 | |
| Myh9 | myosin, heavy polypeptide 9, non-muscle | 0.012 | |
| Ube2c | ubiquitin-conjugating enzyme E2C | 0.012 | |
| Ighmbp2 | immunoglobulin mu binding protein 2 | 0.012 | |
| Cyp51 | cytochrome P450, family 51 | 0.012 | |
| Camsap1 | calmodulin regulated spectrin-associated protein 1 | 0.011 | |
| Igbp1 | immunoglobulin (CD79A) binding protein 1 | 0.011 | |
| Chaf1b | chromatin assembly factor 1, subunit B (p60) | 0.011 | |
| Apoe | apolipoprotein E | 0.011 | |
| Vhl | von Hippel-Lindau tumor suppressor | 0.010 | |
| Tagln2 | transgelin 2 | 0.010 | |
| Casp3 | caspase 3 | 0.010 | |
| Lss | lanosterol synthase | 0.010 | |
| Tnfrsf12a | tumor necrosis factor receptor superfamily, member 12a | 0.010 |