The network for 'response to organophosphorus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to organophosphorus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors.

NameDescriptionProbabilityFunc Analog Organism
CG1927CG1927 gene product from transcript CG1927-RA0.550
AdhAlcohol dehydrogenase0.484
Cyp12a4CG6042 gene product from transcript CG6042-RA0.462
CG5362CG5362 gene product from transcript CG5362-RA0.310
CG15828CG15828 gene product from transcript CG15828-RC0.295
Cyp6a2Cytochrome P450-6a20.235
imdimmune deficiency0.232
Ugt35aUDP-glycosyltransferase 35a0.215
Cyp12d1-pCG30489 gene product from transcript CG30489-RA0.208
Cyp12a5CG11821 gene product from transcript CG11821-RA0.201
JhI-26Juvenile hormone-inducible protein 260.196
CG31743CG31743 gene product from transcript CG31743-RA0.190
Cyp6a23CG10242 gene product from transcript CG10242-RA0.187
IceCG7788 gene product from transcript CG7788-RA0.182
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.171
McrMacroglobulin complement-related0.164
CG12672CG12672 gene product from transcript CG12672-RA0.163
TpiTriose phosphate isomerase0.157
LvpDLarval visceral protein D0.156
CG9510CG9510 gene product from transcript CG9510-RC0.151
CG9772CG9772 gene product from transcript CG9772-RB0.146
CG10562CG10562 gene product from transcript CG10562-RA0.143
Cyp6a21CG10247 gene product from transcript CG10247-RA0.139
Cyp4ac1CG14032 gene product from transcript CG14032-RA0.138
TotATurandot A0.131
AldhAldehyde dehydrogenase0.127
Act88FActin 88F0.125
Cyp12d1-dCG33503 gene product from transcript CG33503-RA0.125
Mpk2CG5475 gene product from transcript CG5475-RB0.119
CG2064CG2064 gene product from transcript CG2064-RA0.116
Cyp6a13CG2397 gene product from transcript CG2397-RA0.116
CG14935CG14935 gene product from transcript CG14935-RA0.115
CG6188CG6188 gene product from transcript CG6188-RA0.114
CG6908CG6908 gene product from transcript CG6908-RA0.112
Cyp4p1Cytochrome P450-4p10.111
CG18522CG18522 gene product from transcript CG18522-RA0.111
ThorCG8846 gene product from transcript CG8846-RA0.108
Gpo-1Glycerophosphate oxidase-10.103
CG9331CG9331 gene product from transcript CG9331-RF0.100
CG11967CG11967 gene product from transcript CG11967-RA0.099
glob1globin 10.097
FatpFatty acid (long chain) transport protein0.096
Ork1Open rectifier K[+] channel 10.096
Acox57D-pacyl-Coenzyme A oxidase at 57D proximal0.091
CG7997CG7997 gene product from transcript CG7997-RB0.091
Atg9Autophagy-specific gene 90.091
E23Early gene at 230.089
CG3759CG3759 gene product from transcript CG3759-RB0.089
CG15784CG15784 gene product from transcript CG15784-RA0.087
Cyp12c1CG4120 gene product from transcript CG4120-RA0.086
Cyp4ac3CG14031 gene product from transcript CG14031-RA0.085
piepineapple eye0.084
CG10550CG10550 gene product from transcript CG10550-RB0.084
EDTPEgg-derived tyrosine phosphatase0.084
CG12171CG12171 gene product from transcript CG12171-RA0.083
CG6830CG6830 gene product from transcript CG6830-RA0.081
Vrp1Verprolin 10.081
CG5778CG5778 gene product from transcript CG5778-RB0.079
Adgf-DAdenosine deaminase-related growth factor D0.079
CG16898CG16898 gene product from transcript CG16898-RA0.079
CG3301CG3301 gene product from transcript CG3301-RB0.078
eyseyes shut0.077
Cyp6a9Cytochrome P450-6a90.077
pyd3CG3027 gene product from transcript CG3027-RA0.077
Fmo-2Flavin-containing monooxygenase 20.075
CG4455CG4455 gene product from transcript CG4455-RA0.074
Cyp9h1CG17577 gene product from transcript CG17577-RA0.074
yip2yippee interacting protein 20.074
nAcRalpha-96Aanicotinic Acetylcholine Receptor alpha 96Aa0.074
CG16704CG16704 gene product from transcript CG16704-RA0.074
CG10560CG10560 gene product from transcript CG10560-RA0.073
EfrER GDP-fucose transporter0.072
CG3091CG3091 gene product from transcript CG3091-RA0.072
ird5immune response deficient 50.071
CG1746CG1746 gene product from transcript CG1746-RA0.070
Osi6Osiris 60.069
Irk2Inwardly rectifying potassium channel 20.068
Ugt86DdCG6633 gene product from transcript CG6633-RB0.067
CG3902CG3902 gene product from transcript CG3902-RA0.067
Ugt36BcCG17932 gene product from transcript CG17932-RB0.067
Lsp1betaLarval serum protein 1 beta0.067
CG32687CG32687 gene product from transcript CG32687-RA0.066
Cyp6a20CG10245 gene product from transcript CG10245-RB0.066
EpacCG34392 gene product from transcript CG34392-RC0.065
CG6283CG6283 gene product from transcript CG6283-RA0.065
CG6045CG6045 gene product from transcript CG6045-RA0.063
CG16965CG16965 gene product from transcript CG16965-RB0.063
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CCNE1cyclin E10.806
ATF3activating transcription factor 30.797
EGR1early growth response 10.756
JUNBjun B proto-oncogene0.710
KCNQ1potassium voltage-gated channel, KQT-like subfamily, member 10.710
FOSFBJ murine osteosarcoma viral oncogene homolog0.705
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.694
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.630
NR4A1nuclear receptor subfamily 4, group A, member 10.584
NR4A2nuclear receptor subfamily 4, group A, member 20.579
FOSBFBJ murine osteosarcoma viral oncogene homolog B0.550
KCNE1potassium voltage-gated channel, Isk-related family, member 10.499
C1Rcomplement component 1, r subcomponent0.424
NR4A3nuclear receptor subfamily 4, group A, member 30.381
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.361
EGR3early growth response 30.353
PRKAR2Aprotein kinase, cAMP-dependent, regulatory, type II, alpha0.326
LIN7Blin-7 homolog B (C. elegans)0.305
IL1R1interleukin 1 receptor, type I0.250
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.248
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.213
IER2immediate early response 20.212
JUNjun proto-oncogene0.186
NOSTRINnitric oxide synthase trafficker0.186
PLATplasminogen activator, tissue0.184
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.162
IL6interleukin 6 (interferon, beta 2)0.158
EGR2early growth response 20.155
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.146
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.143
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.143
ATF2activating transcription factor 20.139
HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)0.123
SPTBN4spectrin, beta, non-erythrocytic 40.123
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.117
PLAUplasminogen activator, urokinase0.111
MAPK14mitogen-activated protein kinase 140.104
FGFR1fibroblast growth factor receptor 10.104
EGFRepidermal growth factor receptor0.104
NEDD4neural precursor cell expressed, developmentally down-regulated 40.103
PRMT2protein arginine methyltransferase 20.102
PDIA3protein disulfide isomerase family A, member 30.099
IGFBP3insulin-like growth factor binding protein 30.095
SOCS3suppressor of cytokine signaling 30.090
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.088
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.086
DRD2dopamine receptor D20.086
ADAM12ADAM metallopeptidase domain 120.086
PHYHIPLphytanoyl-CoA 2-hydroxylase interacting protein-like0.086
NLRC4NLR family, CARD domain containing 40.085
ABCC8ATP-binding cassette, sub-family C (CFTR/MRP), member 80.080
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.080
SOS1son of sevenless homolog 1 (Drosophila)0.073
RAP1ARAP1A, member of RAS oncogene family0.071
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.069
CYP3A7cytochrome P450, family 3, subfamily A, polypeptide 70.068
CASP4caspase 4, apoptosis-related cysteine peptidase0.067
AXLAXL receptor tyrosine kinase0.062
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.061
KSR1kinase suppressor of ras 10.058
IL1RAPinterleukin 1 receptor accessory protein0.057
PDIA6protein disulfide isomerase family A, member 60.056
BTG2BTG family, member 20.056
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.055
DUSP6dual specificity phosphatase 60.055
BCAR1breast cancer anti-estrogen resistance 10.054
AQP7aquaporin 70.052
COL1A2collagen, type I, alpha 20.051
EFEMP2EGF containing fibulin-like extracellular matrix protein 20.050
MDM2Mdm2 p53 binding protein homolog (mouse)0.048
DNM1dynamin 10.048
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.048
SKP2S-phase kinase-associated protein 2 (p45)0.048
CYR61cysteine-rich, angiogenic inducer, 610.046
INO80BINO80 complex subunit B0.045
COL1A1collagen, type I, alpha 10.045
CYP3A5cytochrome P450, family 3, subfamily A, polypeptide 50.044
PROX1prospero homeobox 10.043
NR0B2nuclear receptor subfamily 0, group B, member 20.043
PCK1phosphoenolpyruvate carboxykinase 1 (soluble)0.042
RYR2ryanodine receptor 2 (cardiac)0.042
KCNJ5potassium inwardly-rectifying channel, subfamily J, member 50.041
MSH6mutS homolog 6 (E. coli)0.041
RAPGEF2Rap guanine nucleotide exchange factor (GEF) 20.041
IGF2insulin-like growth factor 2 (somatomedin A)0.040
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.040
TRPC3transient receptor potential cation channel, subfamily C, member 30.040
PLAURplasminogen activator, urokinase receptor0.040
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.039
ATP8ATP synthase F0 subunit 80.038
THBS1thrombospondin 10.038
APOC3apolipoprotein C-III0.038
ANGPT1angiopoietin 10.037
GAB2GRB2-associated binding protein 20.037
USP2ubiquitin specific peptidase 20.037
IGF1insulin-like growth factor 1 (somatomedin C)0.037
RUNDC3ARUN domain containing 3A0.037
RFC1replication factor C (activator 1) 1, 145kDa0.037
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ptgs2prostaglandin-endoperoxide synthase 20.956
Pax2paired box gene 20.891
Amhr2anti-Mullerian hormone type 2 receptor0.754
Gdnfglial cell line derived neurotrophic factor0.712
Casp4caspase 4, apoptosis-related cysteine peptidase0.663
Leprleptin receptor0.540
Kiss1KiSS-1 metastasis-suppressor0.454
FosFBJ osteosarcoma oncogene0.446
Scn5asodium channel, voltage-gated, type V, alpha0.383
Casp1caspase 10.364
Clockcircadian locomotor output cycles kaput0.326
Kitkit oncogene0.291
Arandrogen receptor0.271
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.269
Col4a3collagen, type IV, alpha 30.260
Il1ainterleukin 1 alpha0.236
Cry2cryptochrome 2 (photolyase-like)0.220
Lhx1LIM homeobox protein 10.214
Plauplasminogen activator, urokinase0.202
Selpselectin, platelet0.199
Lyz2lysozyme 20.191
Cdk6cyclin-dependent kinase 60.189
Seleselectin, endothelial cell0.182
FasFas (TNF receptor superfamily member 6)0.167
Cxcl1chemokine (C-X-C motif) ligand 10.166
Thrbthyroid hormone receptor beta0.157
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.152
Jag1jagged 10.142
Cftrcystic fibrosis transmembrane conductance regulator homolog0.135
JunJun oncogene0.124
Il1binterleukin 1 beta0.124
Gbp5guanylate binding protein 50.121
Bcl2B-cell leukemia/lymphoma 20.099
Cyr61cysteine rich protein 610.099
Nr5a1nuclear receptor subfamily 5, group A, member 10.097
Trp53transformation related protein 530.095
Otcornithine transcarbamylase0.095
Ush1gUsher syndrome 1G homolog (human)0.087
Hspa5heat shock protein 50.087
Bdkrb2bradykinin receptor, beta 20.087
Vhlvon Hippel-Lindau tumor suppressor0.080
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.077
Retret proto-oncogene0.071
Nos2nitric oxide synthase 2, inducible0.070
Cxcl2chemokine (C-X-C motif) ligand 20.068
Nos3nitric oxide synthase 3, endothelial cell0.067
Il18interleukin 180.067
PycardPYD and CARD domain containing0.066
Esr1estrogen receptor 1 (alpha)0.066
Il6interleukin 60.066
Lmx1aLIM homeobox transcription factor 1 alpha0.066
Emx2empty spiracles homolog 2 (Drosophila)0.063
Usp2ubiquitin specific peptidase 20.061
Slc4a4solute carrier family 4 (anion exchanger), member 40.059
Hsd11b2hydroxysteroid 11-beta dehydrogenase 20.058
Nos1nitric oxide synthase 1, neuronal0.058
Creld2cysteine-rich with EGF-like domains 20.055
Serpina6serine (or cysteine) peptidase inhibitor, clade A, member 60.055
Dusp1dual specificity phosphatase 10.055
Gata3GATA binding protein 30.054
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.053
Tgfatransforming growth factor alpha0.051
Mmp9matrix metallopeptidase 90.050
Adora3adenosine A3 receptor0.049
Gata6GATA binding protein 60.047
Nppanatriuretic peptide type A0.047
Tbx5T-box 50.046
Otx1orthodenticle homolog 1 (Drosophila)0.046
Pdx1pancreatic and duodenal homeobox 10.045
Wnt10bwingless related MMTV integration site 10b0.043
Pou4f3POU domain, class 4, transcription factor 30.043
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.041
Cyp2a12cytochrome P450, family 2, subfamily a, polypeptide 120.041
Hand1heart and neural crest derivatives expressed transcript 10.041
Pax8paired box gene 80.040
Mybpc3myosin binding protein C, cardiac0.040
Siah2seven in absentia 20.040
FaddFas (TNFRSF6)-associated via death domain0.040
BC100451cDNA sequence BC1004510.040
Gfi1bgrowth factor independent 1B0.039
Ptenphosphatase and tensin homolog0.039
Nr4a1nuclear receptor subfamily 4, group A, member 10.039
Arntlaryl hydrocarbon receptor nuclear translocator-like0.038
Rb1retinoblastoma 10.037
Wt1Wilms tumor 1 homolog0.037
Aim2absent in melanoma 20.037
Il1r1interleukin 1 receptor, type I0.036
Itpr2inositol 1,4,5-triphosphate receptor 20.035
Ch25hcholesterol 25-hydroxylase0.034
Fgf3fibroblast growth factor 30.033
Atf3activating transcription factor 30.033
Egr1early growth response 10.033
LOC100503041PDZ domain-containing protein 7-like0.033
Hif1ahypoxia inducible factor 1, alpha subunit0.032
Cdh23cadherin 23 (otocadherin)0.032
Hsd3b2hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 20.031
Egr2early growth response 20.031
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Egr1early growth response 10.857
Junbjun B proto-oncogene0.776
Aldoaaldolase A, fructose-bisphosphate0.775
Egr2early growth response 20.755
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.743
Mmp3matrix metallopeptidase 30.710
Col1a1collagen, type I, alpha 10.680
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.588
Tpi1triosephosphate isomerase 10.516
Aqp8aquaporin 80.497
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.466
Apohapolipoprotein H (beta-2-glycoprotein I)0.464
Cyp4a10cytochrome P450, family 4, subfamily a, polypeptide 100.458
Nr4a1nuclear receptor subfamily 4, group A, member 10.445
Btg2BTG family, member 20.408
Col5a2collagen, type V, alpha 20.408
Il13interleukin 130.360
Serpind1serpin peptidase inhibitor, clade D (heparin cofactor), member 10.352
Aqp9aquaporin 90.347
Ppardperoxisome proliferator-activated receptor delta0.345
Il1rl1interleukin 1 receptor-like 10.344
FosFBJ osteosarcoma oncogene0.339
Col1a2collagen, type I, alpha 20.333
Col3a1collagen, type III, alpha 10.325
Slc14a2solute carrier family 14 (urea transporter), member 20.323
Slc6a11solute carrier family 6 (neurotransmitter transporter, GABA), member 110.317
Fosl2fos-like antigen 20.303
Slc22a1solute carrier family 22 (organic cation transporter), member 10.298
LOC293989cytochrome P450-like0.298
Serpina3mserine (or cysteine) proteinase inhibitor, clade A, member 3M0.291
Cd38CD38 molecule0.291
Ptgs2prostaglandin-endoperoxide synthase 20.282
Cyp51cytochrome P450, family 510.280
Fgf16fibroblast growth factor 160.267
Cd80Cd80 molecule0.265
Cyp2f4cytochrome P450, family 2, subfamily f, polypeptide 40.260
Slc22a2solute carrier family 22 (organic cation transporter), member 20.258
Ngfnerve growth factor (beta polypeptide)0.251
Cxcl2chemokine (C-X-C motif) ligand 20.242
Klf4Kruppel-like factor 4 (gut)0.239
Gja4gap junction protein, alpha 40.239
Nr5a2nuclear receptor subfamily 5, group A, member 20.239
Atf3activating transcription factor 30.237
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.237
Fkbp4FK506 binding protein 40.232
Il6interleukin 60.230
Atp1a2ATPase, Na+/K+ transporting, alpha 2 polypeptide0.228
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.225
Socs3suppressor of cytokine signaling 30.223
Ctrcchymotrypsin C (caldecrin)0.223
Ptch1patched homolog 1 (Drosophila)0.222
Adam2ADAM metallopeptidase domain 20.217
Sqlesqualene epoxidase0.214
Spp2secreted phosphoprotein 20.213
C3complement component 30.213
Errfi1ERBB receptor feedback inhibitor 10.205
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.204
Akr1c18aldo-keto reductase family 1, member C180.202
Vipvasoactive intestinal peptide0.201
Atp5bATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.200
Gata6GATA binding protein 60.199
Insrinsulin receptor0.198
C1rcomplement component 1, r subcomponent0.197
Fn1fibronectin 10.196
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.195
Cps1carbamoyl-phosphate synthetase 10.194
Gkn1gastrokine 10.188
Capn8calpain 80.188
Ms4a8amembrane-spanning 4-domains, subfamily A, member 8A0.188
Leprleptin receptor0.187
G6pcglucose-6-phosphatase, catalytic subunit0.187
Hrghistidine-rich glycoprotein0.187
Idi1isopentenyl-diphosphate delta isomerase 10.186
Ccl3chemokine (C-C motif) ligand 30.184
Cd4Cd4 molecule0.177
Nr4a3nuclear receptor subfamily 4, group A, member 30.176
Il1r2interleukin 1 receptor, type II0.175
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.172
Gcgroup specific component0.171
Kcne1potassium voltage-gated channel, Isk-related family, member 10.170
Pkm2pyruvate kinase, muscle0.169
Spag4sperm associated antigen 40.169
Dusp6dual specificity phosphatase 60.168
Rbp2retinol binding protein 2, cellular0.166
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.164
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.162
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.162
Chrna2cholinergic receptor, nicotinic, alpha 2 (neuronal)0.160
Rgs1regulator of G-protein signaling 10.160
Il8rainterleukin 8 receptor, alpha0.160
Fcer2Fc fragment of IgE, low affinity II, receptor for (CD23)0.159
Foxa3forkhead box A30.159
Mettl7bmethyltransferase like 7B0.157
Sc4molsterol-C4-methyl oxidase-like0.155
Olr226olfactory receptor 2260.153
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism