The network for 'negative regulation of response to oxidative stress' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of response to oxidative stress

Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress.

NameDescriptionProbabilityFunc Analog Organism
CG8155CG8155 gene product from transcript CG8155-RA0.467
Hsp27Heat shock protein 270.232
mofmales absent on the first0.145
CG8443CG8443 gene product from transcript CG8443-RA0.124
porinCG6647 gene product from transcript CG6647-RA0.072
Hsp26Heat shock protein 260.070
Hsp22Heat shock protein 220.065
Sod2Superoxide dismutase 2 (Mn)0.047
p53CG33336 gene product from transcript CG33336-RB0.034
mubmushroom-body expressed0.033
NLazNeural Lazarillo0.033
Hsp23Heat shock protein 230.029
LnkCG17367 gene product from transcript CG17367-RC0.029
Drp1Dynamin related protein 10.029
Ube3aUbiquitin protein ligase E3A0.028
kermitCG11546 gene product from transcript CG11546-RB0.027
DJ-1alphaCG6646 gene product from transcript CG6646-RA0.025
Ppat-DpckBifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase0.025
TBPHCG10327 gene product from transcript CG10327-RC0.025
SdhBSuccinate dehydrogenase B0.024
Mekk1CG7717 gene product from transcript CG7717-RB0.023
Rab7Rab-protein 70.022
MTF-1Metal response element-binding Transcription Factor-10.022
fhfrataxin homolog0.022
Hsp68Heat shock protein 680.021
HtrA2CG8464 gene product from transcript CG8464-RA0.021
Lk6CG17342 gene product from transcript CG17342-RA0.020
CspCysteine string protein0.019
trpmltransient receptor potential mucolipin0.019
dj-1betaCG1349 gene product from transcript CG1349-RA0.019
CG31108CG31108 gene product from transcript CG31108-RA0.018
AdarAdenosine deaminase acting on RNA0.017
VmatVesicular monoamine transporter0.016
Tom34Translocase of outer membrane 340.016
PargPoly(ADP-ribose) glycohydrolase0.016
Atg6Autophagy-specific gene 60.016
Surf1Surfeit 10.015
CG30410CG30410 gene product from transcript CG30410-RB0.015
Letm1CG4589 gene product from transcript CG4589-RB0.015
GLazGlial Lazarillo0.015
drddrop dead0.015
CG4049CG4049 gene product from transcript CG4049-RA0.014
fs(2)ltoPP43female sterile (2) ltoPP430.014
LaspCG3849 gene product from transcript CG3849-RB0.014
l(1)G0144lethal (1) G01440.013
nanarrow abdomen0.013
ATP7CG1886 gene product from transcript CG1886-RB0.013
CG11866CG11866 gene product from transcript CG11866-RA0.013
CG10984CG10984 gene product from transcript CG10984-RC0.012
CG11902CG11902 gene product from transcript CG11902-RB0.012
Ptp69DProtein tyrosine phosphatase 69D0.012
PpcsPhosphopantothenoylcysteine synthetase0.012
desat1CG5887 gene product from transcript CG5887-RA0.012
Su(var)3-7Suppressor of variegation 3-70.012
Hr39Hormone receptor-like in 390.012
Ilp2Insulin-like peptide 20.012
Patr-1Protein associated with topo II related - 10.012
CG6751CG6751 gene product from transcript CG6751-RA0.012
CG9866CG9866 gene product from transcript CG9866-RA0.012
Cf2Chorion factor 20.012
ThorCG8846 gene product from transcript CG8846-RA0.011
maf-SCG9954 gene product from transcript CG9954-RA0.011
CG15087CG15087 gene product from transcript CG15087-RA0.011
Ulp1CG12359 gene product from transcript CG12359-RA0.011
TbhTyramine beta hydroxylase0.011
Hsc70-4Heat shock protein cognate 40.011
CG7376CG7376 gene product from transcript CG7376-RA0.011
ImpL2Ecdysone-inducible gene L20.011
fbl6CG13213 gene product from transcript CG13213-RB0.011
alpha-Man-IIalpha Mannosidase II0.010
CG10383CG10383 gene product from transcript CG10383-RA0.010
CG12001CG12001 gene product from transcript CG12001-RA0.010
mib2mind bomb 20.010
Ef2bElongation factor 2b0.010
VGATVesicular GABA Transporter0.010
Upf2CG2253 gene product from transcript CG2253-RA0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TRIB3tribbles homolog 3 (Drosophila)0.892
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.890
SFPQsplicing factor proline/glutamine-rich0.767
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.573
VHLvon Hippel-Lindau tumor suppressor0.239
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.227
GAS6growth arrest-specific 60.214
METmet proto-oncogene (hepatocyte growth factor receptor)0.214
FTLferritin, light polypeptide0.152
NFE2L2nuclear factor (erythroid-derived 2)-like 20.141
EGLN1egl nine homolog 1 (C. elegans)0.140
ZNF746zinc finger protein 7460.138
SOD1superoxide dismutase 1, soluble0.115
TOP1topoisomerase (DNA) I0.114
FUSfused in sarcoma0.108
WBP4WW domain binding protein 4 (formin binding protein 21)0.105
CTSDcathepsin D0.084
BAG3BCL2-associated athanogene 30.078
EGLN3egl nine homolog 3 (C. elegans)0.078
KEAP1kelch-like ECH-associated protein 10.075
FBXO7F-box protein 70.075
SIN3ASIN3 homolog A, transcription regulator (yeast)0.066
EEDembryonic ectoderm development0.064
PRDX1peroxiredoxin 10.058
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)0.056
PINK1PTEN induced putative kinase 10.056
APOEapolipoprotein E0.054
ARNTaryl hydrocarbon receptor nuclear translocator0.046
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.046
DDIT3DNA-damage-inducible transcript 30.041
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.040
MAP2K5mitogen-activated protein kinase kinase 50.039
HNRNPA1heterogeneous nuclear ribonucleoprotein A10.036
HGFhepatocyte growth factor (hepapoietin A; scatter factor)0.035
PLXNB1plexin B10.031
HSPB8heat shock 22kDa protein 80.031
KAT2BK(lysine) acetyltransferase 2B0.030
EWSR1Ewing sarcoma breakpoint region 10.028
MAFFv-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)0.027
GAB1GRB2-associated binding protein 10.027
CRYABcrystallin, alpha B0.026
EPAS1endothelial PAS domain protein 10.026
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.024
HNRNPKheterogeneous nuclear ribonucleoprotein K0.024
LATlinker for activation of T cells0.024
DYNLL1dynein, light chain, LC8-type 10.022
SQSTM1sequestosome 10.021
BACH1BTB and CNC homology 1, basic leucine zipper transcription factor 10.020
MAP2K6mitogen-activated protein kinase kinase 60.020
EFTUD2elongation factor Tu GTP binding domain containing 20.020
SSX4synovial sarcoma, X breakpoint 40.019
APOA1apolipoprotein A-I0.019
NFE2L1nuclear factor (erythroid-derived 2)-like 10.019
SMAD2SMAD family member 20.018
ZBED1zinc finger, BED-type containing 10.018
NAMPTnicotinamide phosphoribosyltransferase0.018
OS9osteosarcoma amplified 9, endoplasmic reticulum lectin0.017
PRKCZprotein kinase C, zeta0.017
SLC25A6solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 60.017
RAB5BRAB5B, member RAS oncogene family0.016
APLP2amyloid beta (A4) precursor-like protein 20.016
HDAC1histone deacetylase 10.015
COX7A2cytochrome c oxidase subunit VIIa polypeptide 2 (liver)0.015
CSNK1A1casein kinase 1, alpha 10.013
NONOnon-POU domain containing, octamer-binding0.013
KNG1kininogen 10.013
ZMYM2zinc finger, MYM-type 20.013
MEF2Cmyocyte enhancer factor 2C0.012
PTPRJprotein tyrosine phosphatase, receptor type, J0.012
CTSL1cathepsin L10.012
AHRaryl hydrocarbon receptor0.012
TIMP2TIMP metallopeptidase inhibitor 20.012
FOXO3forkhead box O30.012
UBASH3Bubiquitin associated and SH3 domain containing B0.012
RCOR1REST corepressor 10.012
SKIv-ski sarcoma viral oncogene homolog (avian)0.012
CRYAAcrystallin, alpha A0.012
KHDRBS1KH domain containing, RNA binding, signal transduction associated 10.011
MAP1Bmicrotubule-associated protein 1B0.011
RIPK2receptor-interacting serine-threonine kinase 20.011
ARNTLaryl hydrocarbon receptor nuclear translocator-like0.011
IFNGR1interferon gamma receptor 10.011
SIAH1seven in absentia homolog 1 (Drosophila)0.010
PACRGPARK2 co-regulated0.010
APOC1apolipoprotein C-I0.010
OTUD4OTU domain containing 40.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trib3tribbles homolog 3 (Drosophila)0.581
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.320
Kitlkit ligand0.138
Rps3ribosomal protein S30.110
Gab1growth factor receptor bound protein 2-associated protein 10.103
Ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.099
Cryabcrystallin, alpha B0.097
Gpx1glutathione peroxidase 10.078
Ctsbcathepsin B0.078
Edn1endothelin 10.072
Hspb1heat shock protein 10.071
Fam164cfamily with sequence similarity 164, member C0.069
Eya1eyes absent 1 homolog (Drosophila)0.067
Prrx1paired related homeobox 10.067
Hif1ahypoxia inducible factor 1, alpha subunit0.066
Rspo2R-spondin 2 homolog (Xenopus laevis)0.062
Rb1retinoblastoma 10.059
Mitfmicrophthalmia-associated transcription factor0.057
Prdx1peroxiredoxin 10.055
Acvr1activin A receptor, type 10.050
Rpl6ribosomal protein L60.047
Fxyd1FXYD domain-containing ion transport regulator 10.045
Krt6akeratin 6A0.045
Bag3BCL2-associated athanogene 30.044
Ghrgrowth hormone receptor0.043
Itgb1integrin beta 1 (fibronectin receptor beta)0.037
Cdkn1bcyclin-dependent kinase inhibitor 1B0.036
Aifm1apoptosis-inducing factor, mitochondrion-associated 10.035
Mt2metallothionein 20.032
Mt1metallothionein 10.031
Rplp0ribosomal protein, large, P00.029
Htr3a5-hydroxytryptamine (serotonin) receptor 3A0.029
Ifngr1interferon gamma receptor 10.028
Cdk4cyclin-dependent kinase 40.028
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.027
Vmn2r26vomeronasal 2, receptor 260.027
Rasgrf2RAS protein-specific guanine nucleotide-releasing factor 20.026
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.026
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.025
Ctnnb1catenin (cadherin associated protein), beta 10.024
Tyrp1tyrosinase-related protein 10.024
Svaseminal vesicle antigen0.024
Nphp1nephronophthisis 1 (juvenile) homolog (human)0.023
Pax3paired box gene 30.023
Hspa9heat shock protein 90.023
Lrp2low density lipoprotein receptor-related protein 20.023
Copz2coatomer protein complex, subunit zeta 20.023
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.022
Arandrogen receptor0.022
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 10.022
Dapk3death-associated protein kinase 30.020
Tcn2transcobalamin 20.020
Ltkleukocyte tyrosine kinase0.019
Upk2uroplakin 20.018
Snta1syntrophin, acidic 10.018
Cst8cystatin 8 (cystatin-related epididymal spermatogenic)0.018
Cxcr4chemokine (C-X-C motif) receptor 40.018
P4ha2procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide0.018
Hoxa2homeobox A20.018
Agpat21-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)0.018
Eef1a1eukaryotic translation elongation factor 1 alpha 10.017
Prnpprion protein0.017
Fzd4frizzled homolog 4 (Drosophila)0.017
Kcns2K+ voltage-gated channel, subfamily S, 20.016
Ecm1extracellular matrix protein 10.016
Tppp3tubulin polymerization-promoting protein family member 30.016
Rps5ribosomal protein S50.016
Hpcal1hippocalcin-like 10.015
Cpsf3cleavage and polyadenylation specificity factor 30.015
Meig1meiosis expressed gene 10.015
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.015
Rarbretinoic acid receptor, beta0.015
Gpx3glutathione peroxidase 30.015
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.015
Nat1N-acetyl transferase 10.015
Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.015
Phlda3pleckstrin homology-like domain, family A, member 30.014
FcgrtFc receptor, IgG, alpha chain transporter0.014
Serping1serine (or cysteine) peptidase inhibitor, clade G, member 10.014
Med1mediator complex subunit 10.014
Gadd45agrowth arrest and DNA-damage-inducible 45 alpha0.014
Gfapglial fibrillary acidic protein0.014
Retret proto-oncogene0.014
Npc2Niemann Pick type C20.014
Ubcubiquitin C0.014
Ntf3neurotrophin 30.013
Magmyelin-associated glycoprotein0.013
Sox10SRY-box containing gene 100.013
SeboxSEBOX homeobox0.013
Lipalysosomal acid lipase A0.013
Il6stinterleukin 6 signal transducer0.013
Avpr2arginine vasopressin receptor 20.013
Ftl1ferritin light chain 10.013
Igfbp6insulin-like growth factor binding protein 60.013
Ptprrprotein tyrosine phosphatase, receptor type, R0.013
Tmprss2transmembrane protease, serine 20.013
Adam17a disintegrin and metallopeptidase domain 170.013
Emp2epithelial membrane protein 20.013
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism