The network for 'negative regulation of meiotic cell cycle' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of meiotic cell cycle

Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.

NameDescriptionProbabilityFunc Analog Organism
mxcmulti sex combs0.369
nejnejire0.253
CycACyclin A0.207
DoaDarkener of apricot0.204
RPA2Replication protein A20.177
SxlSex lethal0.129
His2AvHistone H2A variant0.126
CycJCyclin J0.122
Cap-GCG34438 gene product from transcript CG34438-RF0.117
AlyCG1101 gene product from transcript CG1101-RA0.106
cdc2cCG10498 gene product from transcript CG10498-RC0.106
prodproliferation disrupter0.104
Akt1CG4006 gene product from transcript CG4006-RA0.095
bratbrain tumor0.092
Rpd3CG7471 gene product from transcript CG7471-RA0.084
dapdacapo0.080
RfC4Replication factor C subunit 40.072
Taf6TBP-associated factor 60.070
mus209mutagen-sensitive 2090.067
fzyfizzy0.064
lokloki0.063
MRG15CG6363 gene product from transcript CG6363-RA0.063
pUf68poly U binding factor 68kD0.056
Snr1Snf5-related 10.055
Bj1Bj1 protein0.052
ecdecdysoneless0.052
cazcabeza0.052
CkIIalphaCasein kinase II alpha subunit0.051
Su(var)205Suppressor of variegation 2050.051
piwiCG6122 gene product from transcript CG6122-RA0.051
mod(mdg4)modifier of mdg40.050
Kmn1kinetochore Mis12-Ndc80 network component 10.049
Src64BSrc oncogene at 64B0.047
O-fut1O-fucosyltransferase 10.044
CrebB-17ACyclic-AMP response element binding protein B at 17A0.044
rlrolled0.042
tra2transformer 20.042
SelDSelenide,water dikinase0.042
DNApol-deltaDNA-polymerase-delta0.041
pzgputzig0.040
feofascetto0.039
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.039
Mcm6Minichromosome maintenance 60.037
jumujumeau0.037
DrefDNA replication-related element factor0.036
BEAF-32Boundary element-associated factor of 32kD0.034
mei-9meiotic 90.034
CG9135CG9135 gene product from transcript CG9135-RB0.033
eggeggless0.032
cmetCENP-meta0.032
ovoCG6824 gene product from transcript CG6824-RE0.031
RbfRetinoblastoma-family protein0.030
Taf1TBP-associated factor 10.030
CycECyclin E0.030
pavpavarotti0.029
Su(var)2-10Suppressor of variegation 2-100.029
cgcombgap0.029
sqdsquid0.028
pimpimples0.028
CycHCyclin H0.028
gppgrappa0.027
Map60Microtubule-associated protein 600.026
CycBCyclin B0.026
Nop60BNucleolar protein at 60B0.026
OteOtefin0.025
Mcm7Minichromosome maintenance 70.025
oskoskar0.024
ph-ppolyhomeotic proximal0.024
Dsor1Downstream of raf10.024
Cenp-CCG31258 gene product from transcript CG31258-RA0.023
SceSex combs extra0.023
CG10267CG10267 gene product from transcript CG10267-RB0.023
U2af50U2 small nuclear riboprotein auxiliary factor 500.023
CG4973CG4973 gene product from transcript CG4973-RA0.023
TH1CG9984 gene product from transcript CG9984-RA0.022
Cul-5Cullin-50.021
snRNP-U1-70Ksmall ribonucleoprotein particle U1 subunit 70K0.021
spn-Bspindle B0.021
l(1)G0095lethal (1) G00950.021
Orc1Origin recognition complex subunit 10.020
CycCCyclin C0.020
Bap55Brahma associated protein 55kD0.020
nosnanos0.019
katanin-60katanin 600.019
poloCG12306 gene product from transcript CG12306-RA0.018
mus101mutagen-sensitive 1010.018
dshdishevelled0.018
CG5745CG5745 gene product from transcript CG5745-RA0.017
piepineapple eye0.017
cavcaravaggio0.017
alphaTub67Calpha-Tubulin at 67C0.017
vasvasa0.017
fufused0.017
hephhephaestus0.016
mus301mutagen-sensitive 3010.016
barrbarren0.016
gfzfGST-containing FLYWCH zinc-finger protein0.016
Vsx2CG33980 gene product from transcript CG33980-RA0.015
mus308mutagen-sensitive 3080.015
slmbsupernumerary limbs0.015
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
unguracil-DNA glycosylase0.074
ncapd2non-SMC condensin I complex, subunit D20.057
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.031
LOC554173abnormal spindles0.029
slbpstem-loop binding protein0.026
mibmind bomb0.023
ncapgnon-SMC condensin I complex, subunit G0.022
kpna2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.021
setd8aSET domain containing (lysine methyltransferase) 8a0.021
smc4structural maintenance of chromosomes 40.021
gins3GINS complex subunit 30.020
rpa3replication protein A30.020
tymsthymidylate synthase0.019
whsc1Wolf-Hirschhorn syndrome candidate 10.018
zgc:92648zgc:926480.017
wdhd1WD repeat and HMG-box DNA binding protein 10.017
dnmt1DNA (cytosine-5-)-methyltransferase 10.016
rad21RAD21 homolog (S. pombe)0.015
leprleptin receptor0.015
orc6origin recognition complex, subunit 60.014
zgc:110113zgc:1101130.014
pcsk2proprotein convertase subtilisin/kexin type 20.014
pgrprogesterone receptor0.012
ezh2enhancer of zeste homolog 2 (Drosophila)0.012
smc3structural maintenance of chromosomes 30.012
hdac1histone deacetylase 10.012
zgc:55701zgc:557010.012
esco2establishment of cohesion 1 homolog 20.012
stilTAL1 (SCL) interrupting locus0.011
suv39h1bsuppressor of variegation 3-9 homolog 1b0.011
msh2mutS homolog 2 (E. coli)0.011
dhfrdihydrofolate reductase0.011
zgc:113210zgc:1132100.011
bonbonnie and clyde0.011
dutdUTP pyrophosphatase0.011
atad5aATPase family, AAA domain containing 5a0.011
chaf1bchromatin assembly factor 1, subunit B0.010
smad5MAD homolog 5 (Drosophila)0.010
ints6integrator complex subunit 60.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PCNAproliferating cell nuclear antigen0.992
CCNA2cyclin A20.983
NCAPHnon-SMC condensin I complex, subunit H0.980
CDC27cell division cycle 27 homolog (S. cerevisiae)0.882
CDK1cyclin-dependent kinase 10.801
SKP2S-phase kinase-associated protein 2 (p45)0.796
CCNB1cyclin B10.796
SMC4structural maintenance of chromosomes 40.730
CDC20cell division cycle 20 homolog (S. cerevisiae)0.420
NCAPD2non-SMC condensin I complex, subunit D20.270
HUS1HUS1 checkpoint homolog (S. pombe)0.262
ANAPC4anaphase promoting complex subunit 40.209
NCAPG2non-SMC condensin II complex, subunit G20.208
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.202
ANAPC7anaphase promoting complex subunit 70.189
ANAPC1anaphase promoting complex subunit 10.165
CKS2CDC28 protein kinase regulatory subunit 20.143
RBBP8retinoblastoma binding protein 80.103
SMC2structural maintenance of chromosomes 20.100
CKS1BCDC28 protein kinase regulatory subunit 1B0.099
AKAP11A kinase (PRKA) anchor protein 110.095
CCNE1cyclin E10.094
RPA1replication protein A1, 70kDa0.092
CDK2cyclin-dependent kinase 20.090
ANAPC5anaphase promoting complex subunit 50.085
MCM6minichromosome maintenance complex component 60.083
CDC23cell division cycle 23 homolog (S. cerevisiae)0.080
CDC6cell division cycle 6 homolog (S. cerevisiae)0.075
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)0.070
PRKAR1Aprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)0.063
AKIP1A kinase (PRKA) interacting protein 10.063
MSH6mutS homolog 6 (E. coli)0.059
RYR2ryanodine receptor 2 (cardiac)0.055
CCNE2cyclin E20.053
SIP1survival of motor neuron protein interacting protein 10.052
MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)0.049
ORC1origin recognition complex, subunit 10.044
POLA1polymerase (DNA directed), alpha 1, catalytic subunit0.042
PRKAR2Bprotein kinase, cAMP-dependent, regulatory, type II, beta0.042
NCAPD3non-SMC condensin II complex, subunit D30.041
NCAPH2non-SMC condensin II complex, subunit H20.039
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)0.034
CDC26cell division cycle 26 homolog (S. cerevisiae)0.034
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)0.032
CDC7cell division cycle 7 homolog (S. cerevisiae)0.031
DSN1DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)0.031
RFC3replication factor C (activator 1) 3, 38kDa0.031
HDAC3histone deacetylase 30.029
CENPQcentromere protein Q0.028
CDT1chromatin licensing and DNA replication factor 10.028
CDC16cell division cycle 16 homolog (S. cerevisiae)0.028
CCNB2cyclin B20.028
ATAD2ATPase family, AAA domain containing 20.027
UBR7ubiquitin protein ligase E3 component n-recognin 7 (putative)0.027
NCAPGnon-SMC condensin I complex, subunit G0.027
DNAJC9DnaJ (Hsp40) homolog, subfamily C, member 90.025
MCM2minichromosome maintenance complex component 20.024
PRPS1phosphoribosyl pyrophosphate synthetase 10.024
MSH3mutS homolog 3 (E. coli)0.023
TMEM194Atransmembrane protein 194A0.021
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.020
TAF5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa0.020
DONSONdownstream neighbor of SON0.019
DYRK1Bdual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B0.019
UNGuracil-DNA glycosylase0.018
CCT8chaperonin containing TCP1, subunit 8 (theta)0.018
MUS81MUS81 endonuclease homolog (S. cerevisiae)0.017
MCM3minichromosome maintenance complex component 30.017
SMC1Astructural maintenance of chromosomes 1A0.017
DBF4DBF4 homolog (S. cerevisiae)0.016
C13orf27chromosome 13 open reading frame 270.016
RAD21RAD21 homolog (S. pombe)0.016
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.016
RFWD3ring finger and WD repeat domain 30.016
C13orf34chromosome 13 open reading frame 340.015
RFC1replication factor C (activator 1) 1, 145kDa0.014
NUSAP1nucleolar and spindle associated protein 10.014
GPSM2G-protein signaling modulator 20.014
ANAPC11anaphase promoting complex subunit 110.014
PLK4polo-like kinase 40.014
PRKAR2Aprotein kinase, cAMP-dependent, regulatory, type II, alpha0.014
MAPK3mitogen-activated protein kinase 30.014
ZNF207zinc finger protein 2070.013
KIF18Akinesin family member 18A0.013
MCM4minichromosome maintenance complex component 40.013
TFDP1transcription factor Dp-10.013
ARPC4actin related protein 2/3 complex, subunit 4, 20kDa0.013
ASF1AASF1 anti-silencing function 1 homolog A (S. cerevisiae)0.013
WASF2WAS protein family, member 20.013
RPA2replication protein A2, 32kDa0.013
FBXO5F-box protein 50.013
PPP4R1protein phosphatase 4, regulatory subunit 10.012
CCDC99coiled-coil domain containing 990.012
EVI5ecotropic viral integration site 50.012
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.012
SETD7SET domain containing (lysine methyltransferase) 70.012
VAPBVAMP (vesicle-associated membrane protein)-associated protein B and C0.012
PRKAR1Bprotein kinase, cAMP-dependent, regulatory, type I, beta0.011
STK17Aserine/threonine kinase 17a0.011
SORBS3sorbin and SH3 domain containing 30.011
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ccna2cyclin A20.452
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.344
Pcnaproliferating cell nuclear antigen0.279
Ccnb1cyclin B10.222
Trim59tripartite motif-containing 590.098
Plk4polo-like kinase 4 (Drosophila)0.079
Prc1protein regulator of cytokinesis 10.070
Smc4structural maintenance of chromosomes 40.069
Cdca8cell division cycle associated 80.060
Ccne1cyclin E10.060
Top2atopoisomerase (DNA) II alpha0.058
Cdk1cyclin-dependent kinase 10.058
Tmpothymopoietin0.053
Ergavian erythroblastosis virus E-26 (v-ets) oncogene related0.052
Ccnb2cyclin B20.051
Cenpjcentromere protein J0.049
Birc5baculoviral IAP repeat-containing 50.048
Anlnanillin, actin binding protein0.041
C330027C09RikRIKEN cDNA C330027C09 gene0.040
Kif20akinesin family member 20A0.039
Cnot1CCR4-NOT transcription complex, subunit 10.036
Kif11kinesin family member 110.035
Pou5f1POU domain, class 5, transcription factor 10.034
Ncoa3nuclear receptor coactivator 30.033
Pias1protein inhibitor of activated STAT 10.032
Naspnuclear autoantigenic sperm protein (histone-binding)0.032
Hmgb2high mobility group box 20.032
Sufusuppressor of fused homolog (Drosophila)0.032
Pola1polymerase (DNA directed), alpha 10.031
Prkar2bprotein kinase, cAMP dependent regulatory, type II beta0.030
Kif23kinesin family member 230.029
Mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.028
Ckap2cytoskeleton associated protein 20.023
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.021
Lin9lin-9 homolog (C. elegans)0.021
Hmmrhyaluronan mediated motility receptor (RHAMM)0.021
Atad2ATPase family, AAA domain containing 20.020
Racgap1Rac GTPase-activating protein 10.020
Hellshelicase, lymphoid specific0.019
2610039C10RikRIKEN cDNA 2610039C10 gene0.019
Kif22kinesin family member 220.018
Arpc4actin related protein 2/3 complex, subunit 40.018
Mki67antigen identified by monoclonal antibody Ki 670.018
Aurkaaurora kinase A0.017
C1qtnf5C1q and tumor necrosis factor related protein 50.017
Ncaphnon-SMC condensin I complex, subunit H0.017
Cdk4cyclin-dependent kinase 40.017
Ect2ect2 oncogene0.016
Lsm2LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.016
H1histocompatibility 10.016
G2e3G2/M-phase specific E3 ubiquitin ligase0.016
Gnb2guanine nucleotide binding protein (G protein), beta 20.016
Trp53transformation related protein 530.016
Prkar1aprotein kinase, cAMP dependent regulatory, type I, alpha0.015
Cdk2cyclin-dependent kinase 20.015
Zfp101zinc finger protein 1010.015
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.015
Bub1budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)0.015
Adrb1adrenergic receptor, beta 10.015
Rrm1ribonucleotide reductase M10.014
Aspmasp (abnormal spindle)-like, microcephaly associated (Drosophila)0.014
ArhgdiaRho GDP dissociation inhibitor (GDI) alpha0.014
Nusap1nucleolar and spindle associated protein 10.014
Pds5bPDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)0.013
Mcm4minichromosome maintenance deficient 4 homolog (S. cerevisiae)0.013
Cenpacentromere protein A0.013
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.013
Dtldenticleless homolog (Drosophila)0.013
Guca2bguanylate cyclase activator 2b (retina)0.012
Pkd1polycystic kidney disease 1 homolog0.012
Mdm4transformed mouse 3T3 cell double minute 40.012
Atp2c2ATPase, Ca++ transporting, type 2C, member 20.011
Kif2ckinesin family member 2C0.011
Terf1telomeric repeat binding factor 10.011
Zfp42zinc finger protein 420.011
Add1adducin 1 (alpha)0.011
Cwh43cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)0.010
Aurkbaurora kinase B0.010
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
HXT4Hxt4p0.913
RED1Red1p0.834
SNT1Snt1p0.785
HXT2Hxt2p0.777
PPH22Pph22p0.685
MEK1Mek1p0.602
PSY2Psy2p0.485
MTH1Mth1p0.467
ZDS1Zds1p0.442
YCS4Ycs4p0.344
HOS4Hos4p0.322
HOP1Hop1p0.319
HOS2Hos2p0.212
PSY4Psy4p0.203
YAR028Whypothetical protein0.189
HXT3Hxt3p0.181
RAD17Rad17p0.173
GIS1Gis1p0.154
GAL2Gal2p0.149
BRN1Brn1p0.148
MSN4Msn4p0.147
SIF2Sif2p0.143
CCT2Cct2p0.135
STE4Ste4p0.125
PSD2Psd2p0.122
THI22Thi22p0.116
URA8Ura8p0.113
HXT8Hxt8p0.112
PPH3Pph3p0.104
RAD9Rad9p0.094
HXT1Hxt1p0.093
YHR033Whypothetical protein0.092
GIS4Gis4p0.091
PHO81Pho81p0.085
SCS7Scs7p0.083
CPR1Cpr1p0.082
NOC3Noc3p0.079
MRL1Mrl1p0.075
RAD24Rad24p0.072
HSL1Hsl1p0.067
SMC4Smc4p0.067
HOT1Hot1p0.066
ZIP1Zip1p0.062
YNR073Chypothetical protein0.061
SRS2Srs2p0.058
TAX4Tax4p0.057
COS111Cos111p0.056
YMR279Chypothetical protein0.055
PDS1Pds1p0.054
GPR1Gpr1p0.054
YMR259Chypothetical protein0.053
PDR15Pdr15p0.053
CDC55Cdc55p0.053
CKA1Cka1p0.051
PPH21Pph21p0.050
GAL10Gal10p0.049
SMC2Smc2p0.048
UGA2Uga2p0.048
GLO3Glo3p0.046
HXT9Hxt9p0.046
RGC1Rgc1p0.046
AZF1Azf1p0.046
YMR315Whypothetical protein0.045
HXT11Hxt11p0.045
YMR155Whypothetical protein0.045
MPH3Mph3p0.044
MEC1Mec1p0.043
MNR2Mnr2p0.041
MIG2Mig2p0.041
IZH4Izh4p0.041
PWP1Pwp1p0.039
TPK2Tpk2p0.039
PCL1Pcl1p0.039
CMD1Cmd1p0.039
NUC1Nuc1p0.038
SLG1Slg1p0.038
CCC2Ccc2p0.038
IMA4Ima4p0.037
GUD1Gud1p0.037
RCO1Rco1p0.036
HXT10Hxt10p0.036
RIO2Rio2p0.036
POT1Pot1p0.035
ZIP2Zip2p0.035
HHO1Hho1p0.035
PHO84Pho84p0.034
DFM1Dfm1p0.034
PIG1Pig1p0.034
MOT3Mot3p0.034
SMA1Sma1p0.034
SIP2Sip2p0.033
POL30Pol30p0.033
SET3Set3p0.032
FRE7Fre7p0.032
SWT1Swt1p0.032
HXT7Hxt7p0.032
SOR1Sor1p0.032
BDH1Bdh1p0.031
CMK1Cmk1p0.031
KIN1Kin1p0.031