The network for 'regulation of epithelial cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of epithelial cell differentiation

Any process that modulates the frequency, rate or extent of epithelial cell differentiation.

NameDescriptionProbabilityFunc Analog Organism
MadMothers against dpp0.789
amosabsent MD neurons and olfactory sensilla0.692
DadDaughters against dpp0.645
mbcmyoblast city0.631
bowlbrother of odd with entrails limited0.543
E(spl)Enhancer of split0.501
emcextra macrochaetae0.458
HLHm7E(spl) region transcript m70.432
rheaCG6831 gene product from transcript CG6831-RA0.407
lqfliquid facets0.285
m2E(spl) region transcript m20.232
eyaeyes absent0.218
Myo31DFMyosin 31DF0.210
Pka-C1cAMP-dependent protein kinase 10.208
l(2)gllethal (2) giant larvae0.203
HLHmgammaE(spl) region transcript mgamma0.193
PoxnPox neuro0.189
CG12424CG12424 gene product from transcript CG12424-RC0.140
TolloCG6890 gene product from transcript CG6890-RA0.136
G-salpha60AG protein salpha 60A0.132
opaodd paired0.125
Abd-BAbdominal B0.125
nocno ocelli0.124
NotumCG13076 gene product from transcript CG13076-RB0.116
Pk61CProtein kinase 61C0.113
Ras85DRas oncogene at 85D0.110
Su(z)12CG8013 gene product from transcript CG8013-RA0.108
Rac1CG2248 gene product from transcript CG2248-RA0.103
emsempty spiracles0.102
aopanterior open0.102
Smg5CG8954 gene product from transcript CG8954-RA0.101
HLHm5E(spl) region transcript m50.097
Kr-h1Kruppel homolog 10.093
dallydivision abnormally delayed0.093
HLHmbetaE(spl) region transcript mbeta0.091
spensplit ends0.091
fs(1)hfemale sterile (1) homeotic0.091
CycECyclin E0.090
m4E(spl) region transcript m40.078
Tsc1CG6147 gene product from transcript CG6147-RA0.078
Su(H)Suppressor of Hairless0.076
Nrx-IVNeurexin IV0.075
oddodd skipped0.075
rolsrolling pebbles0.073
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
hlh-2Protein HLH-20.076
cnd-1Protein CND-10.059
elt-6Protein ELT-60.053
inx-3Protein INX-30.046
egl-18Protein EGL-180.043
hnd-1Protein HND-10.037
nhr-67Protein NHR-670.037
ten-1Protein TEN-10.036
nhr-2Protein NHR-20.036
lin-29Protein LIN-290.032
ZK742.2Protein ZK742.20.030
sfxn-5Protein SFXN-50.026
mls-2Protein MLS-20.026
CELE_F26G5.1Protein F26G5.10.026
CELE_Y69A2AR.8Protein Y69A2AR.80.025
wrk-1Protein WRK-10.025
pes-1Protein PES-10.025
CELE_M05D6.3Protein M05D6.30.025
flt-1Protein FLT-10.025
elc-1Protein ELC-10.024
pha-4Protein PHA-40.023
C55C3.4Protein C55C3.40.023
gon-2Protein GON-20.023
ndg-4Protein NDG-40.023
let-60Protein LET-600.023
par-1Protein PAR-10.023
tbx-33Protein TBX-330.023
unc-53Protein UNC-530.022
cam-1Protein CAM-10.022
C07E3.4Protein C07E3.40.022
egl-13Protein EGL-130.022
hlh-11Protein HLH-110.022
egl-15Protein EGL-150.022
CELE_F26D2.10Protein F26D2.100.022
pry-1Protein PRY-10.021
CELE_C27D8.2Protein C27D8.20.021
hch-1Protein HCH-10.021
F57H12.5Protein F57H12.50.021
sna-2Protein SNA-20.021
F39B2.1Protein F39B2.10.021
rsp-3Protein RSP-30.021
egl-46Protein EGL-460.021
phf-10Protein PHF-100.021
ptp-1Protein PTP-10.020
nhr-177Protein NHR-1770.020
egl-8Protein EGL-80.020
fkh-2Protein FKH-20.020
K07A3.3Protein K07A3.30.020
bam-2Protein BAM-20.020
trim-9Protein TRIM-90.020
W02B8.1Protein W02B8.10.020
lntl-1Protein LNTL-10.020
hlh-1Protein HLH-10.020
oac-19Protein OAC-190.020
fmi-1Protein FMI-10.020
F55A3.2Protein F55A3.20.020
CELE_F53C11.4Protein F53C11.40.019
zip-7Protein ZIP-70.019
T13A10.1Protein T13A10.10.019
unc-130Protein UNC-1300.019
egl-30Protein EGL-300.019
ZK1053.4Protein ZK1053.40.019
elt-3Protein ELT-30.019
R09A8.5Protein R09A8.50.019
egl-5Protein EGL-50.019
fbxc-40Protein FBXC-400.019
dpy-22Protein DPY-220.019
mnp-1Protein MNP-10.018
F33H2.5Protein F33H2.50.018
unc-73Protein UNC-730.018
tag-76Protein TAG-760.018
ZK177.1Protein ZK177.10.018
F55C12.2Protein F55C12.20.018
sma-6Protein SMA-60.018
CELE_F36D3.5Protein F36D3.50.018
otpl-3Protein OTPL-30.018
sex-1Protein SEX-10.018
Y55F3AM.10Protein Y55F3AM.100.018
tbx-8Protein TBX-80.018
elt-2Protein ELT-20.018
pxf-1Protein PXF-10.018
K04B12.2Protein K04B12.20.018
akt-2Protein AKT-20.018
swsn-2.1Protein SWSN-2.10.018
npp-4Protein NPP-40.018
sas-4Protein SAS-40.018
clec-196Protein CLEC-1960.018
lin-17Protein LIN-170.018
sek-1Protein SEK-10.018
F21A10.2Protein F21A10.20.018
math-4Protein MATH-40.018
egl-27Protein EGL-270.018
F12F6.1Protein F12F6.10.018
tra-2Protein TRA-20.018
T06C10.3Protein T06C10.30.018
T28F4.3Protein T28F4.30.018
pqn-62Protein PQN-620.018
F47B3.6Protein F47B3.60.018
pde-4Protein PDE-40.018
egl-36Protein EGL-360.017
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
fgf8afibroblast growth factor 8 a0.545
pax2apaired box gene 2a0.524
gli1GLI-Kruppel family member 10.172
shhasonic hedgehog a0.130
kdrlkinase insert domain receptor like0.122
bmp4bone morphogenetic protein 40.117
ptf1apancreas specific transcription factor, 1a0.085
notch1bnotch homolog 1b0.079
hnf1baHNF1 homeobox Ba0.067
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.053
wt1awilms tumor 1a0.052
eng2aengrailed 2a0.051
tbx24T-box 240.042
six4asine oculis homeobox homolog 4a0.039
trpv6transient receptor potential cation channel, subfamily V, member 60.034
atoh1batonal homolog 1b0.033
atoh1aatonal homolog 1a0.030
rnasel1ribonuclease like 10.030
gli2aGLI-Kruppel family member GLI2a0.030
pax6apaired box gene 6a0.030
foxa2forkhead box A20.029
irx4biroquois homeobox protein 4b0.028
gata5GATA-binding protein 50.028
sox9bSRY-box containing gene 9b0.028
tfap2atranscription factor AP-2 alpha0.026
nkx2.2aNK2 transcription factor related 2a0.026
lmx1b.1LIM homeobox transcription factor 1, beta 10.025
pax6bpaired box gene 6b0.024
jag2jagged 20.024
notch3notch homolog 30.023
gdf6agrowth differentiation factor 6a0.023
gata2aGATA-binding protein 2a0.023
slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.022
tbx5aT-box 5a0.021
jag1bjagged 1b0.021
dlx3bdistal-less homeobox gene 3b0.021
fstafollistatin a0.020
crb2acrumbs homolog 2a0.020
tp63tumor protein p630.019
pitx2paired-like homeodomain transcription factor 20.019
lhx1aLIM homeobox 1a0.019
foxc1aforkhead box C1a0.018
myf5myogenic factor 50.018
chrna7cholinergic receptor, nicotinic, alpha polypeptide 70.017
six4bsine oculis homeobox homolog 4b0.017
tbx2bT-box 2b0.017
tbx20T-box 200.016
alcamaactivated leukocyte cell adhesion molecule a0.015
runx2brunt-related transcription factor 2b0.015
tmem2transmembrane protein 20.015
adipor2adiponectin receptor 20.015
wnt2bbwingless-type MMTV integration site family, member 2Bb0.014
gja3gap junction protein, alpha 30.014
cry2bcryptochrome 2b0.013
tshbthyroid stimulating hormone, beta subunit0.013
cdh23cadherin-like 230.013
foxi3bforkhead box I3b0.013
pax8paired box gene 80.012
fn1fibronectin 10.012
raraaretinoic acid receptor, alpha a0.012
olig2oligodendrocyte lineage transcription factor 20.012
ptch2patched 20.012
igf3insulin-like growth factor 30.012
gbx2gastrulation brain homeo box 20.012
tbx1T-box 10.012
ascl1aachaete-scute complex-like 1a (Drosophila)0.012
tbx6T-box gene 60.011
vhlvon Hippel-Lindau tumor suppressor0.011
fgfr4fibroblast growth factor receptor 40.011
gata3GATA-binding protein 30.011
ctsl1bcathepsin L, 1 b0.011
cav1caveolin 10.010
nppanatriuretic peptide precursor A0.010
per3period homolog 3 (Drosophila)0.010
wtipWilms tumor 1 interacting protein0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BBS10Bardet-Biedl syndrome 100.538
NRP1neuropilin 10.502
TJP1tight junction protein 1 (zona occludens 1)0.427
CDK6cyclin-dependent kinase 60.426
VEGFAvascular endothelial growth factor A0.415
RARAretinoic acid receptor, alpha0.378
PRKAR1Aprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)0.343
BMPR1Abone morphogenetic protein receptor, type IA0.321
KRT5keratin 50.315
RUNX1runt-related transcription factor 10.285
NCOR2nuclear receptor corepressor 20.283
NR4A1nuclear receptor subfamily 4, group A, member 10.253
SMAD2SMAD family member 20.248
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.246
EP300E1A binding protein p3000.216
NCOR1nuclear receptor corepressor 10.214
CCNE1cyclin E10.209
SMAD4SMAD family member 40.206
NFE2L2nuclear factor (erythroid-derived 2)-like 20.193
CREBBPCREB binding protein0.183
JAG1jagged 10.159
GSK3Bglycogen synthase kinase 3 beta0.134
ZMYND11zinc finger, MYND-type containing 110.133
HOXB5homeobox B50.127
ARandrogen receptor0.102
RXRAretinoid X receptor, alpha0.101
ESR1estrogen receptor 10.099
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.094
CLOCKclock homolog (mouse)0.092
SRSF4serine/arginine-rich splicing factor 40.090
NRIP1nuclear receptor interacting protein 10.085
HOXA10homeobox A100.082
HOXA7homeobox A70.079
RB1retinoblastoma 10.075
HOXB9homeobox B90.075
EGFRepidermal growth factor receptor0.075
NCOA1nuclear receptor coactivator 10.075
HOXA11homeobox A110.075
NOTCH3notch 30.073
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.070
CDH5cadherin 5, type 2 (vascular endothelium)0.070
SRSF6serine/arginine-rich splicing factor 60.068
NOTCH1notch 10.063
SHC2SHC (Src homology 2 domain containing) transforming protein 20.063
FOXO1forkhead box O10.063
ARNTLaryl hydrocarbon receptor nuclear translocator-like0.062
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.060
SMAD7SMAD family member 70.059
INSRinsulin receptor0.058
CTBP1C-terminal binding protein 10.056
NKX2-1NK2 homeobox 10.056
GJA1gap junction protein, alpha 1, 43kDa0.055
GRB10growth factor receptor-bound protein 100.053
HNF4Ahepatocyte nuclear factor 4, alpha0.052
GATA2GATA binding protein 20.051
NCOA2nuclear receptor coactivator 20.051
TJP2tight junction protein 2 (zona occludens 2)0.049
SUFUsuppressor of fused homolog (Drosophila)0.048
HOXB7homeobox B70.047
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.046
SMAD1SMAD family member 10.044
AKAP11A kinase (PRKA) anchor protein 110.042
TCF4transcription factor 40.042
STK36serine/threonine kinase 360.041
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.041
NME2non-metastatic cells 2, protein (NM23B) expressed in0.041
HOXC10homeobox C100.040
FSTL1follistatin-like 10.040
MSX1msh homeobox 10.038
STAT5Asignal transducer and activator of transcription 5A0.038
ZNF746zinc finger protein 7460.037
PTPN1protein tyrosine phosphatase, non-receptor type 10.037
TGIF1TGFB-induced factor homeobox 10.037
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.037
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.036
NDPNorrie disease (pseudoglioma)0.036
TCF12transcription factor 120.035
DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 170.035
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.034
ESR2estrogen receptor 2 (ER beta)0.034
KANK2KN motif and ankyrin repeat domains 20.034
HOXB6homeobox B60.034
CCND3cyclin D30.032
E2F1E2F transcription factor 10.032
CABLES1Cdk5 and Abl enzyme substrate 10.032
HOXA5homeobox A50.032
LAD1ladinin 10.031
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.030
WHSC1L1Wolf-Hirschhorn syndrome candidate 1-like 10.029
CNOT8CCR4-NOT transcription complex, subunit 80.029
HOXA2homeobox A20.029
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.028
WNT3Awingless-type MMTV integration site family, member 3A0.028
THRAthyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)0.027
PKP3plakophilin 30.027
CDCA5cell division cycle associated 50.027
HOXB3homeobox B30.027
WNT5Awingless-type MMTV integration site family, member 5A0.027
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Gja5gap junction protein, alpha 50.226
Slc12a1solute carrier family 12 (sodium/potassium/chloride transporters), member 10.154
Prdm2PR domain containing 2, with ZNF domain0.137
Smad7SMAD family member 70.106
Gjb3gap junction protein, beta 30.100
Cd40lgCD40 ligand0.094
Unc5bunc-5 homolog B (C. elegans)0.093
Nr5a2nuclear receptor subfamily 5, group A, member 20.090
Arntaryl hydrocarbon receptor nuclear translocator0.083
Foxd1forkhead box D10.075
Ddr1discoidin domain receptor tyrosine kinase 10.068
Cishcytokine inducible SH2-containing protein0.065
Rararetinoic acid receptor, alpha0.064
Tgfbr3transforming growth factor, beta receptor III0.061
B4galt1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 10.061
Vdrvitamin D (1,25- dihydroxyvitamin D3) receptor0.061
Oxtoxytocin, prepropeptide0.055
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.053
Reg3bregenerating islet-derived 3 beta0.052
Gja4gap junction protein, alpha 40.050
Hbbhemoglobin, beta0.049
RT1-M5RT1 class Ib, locus M50.047
Eif2ak2eukaryotic translation initiation factor 2-alpha kinase 20.045
Rod1ROD1 regulator of differentiation 1 (S. pombe)0.043
Ppypancreatic polypeptide0.043
Mef2dmyocyte enhancer factor 2D0.042
Galr3galanin receptor 30.042
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.039
Il1r1interleukin 1 receptor, type I0.039
Ebf1early B-cell factor 10.038
Fat2FAT tumor suppressor homolog 2 (Drosophila)0.035
LOC100362108poly (ADP-ribose) polymerase family, member 100.035
Flt1FMS-related tyrosine kinase 10.034
Myh9myosin, heavy chain 9, non-muscle0.032
Parp14poly (ADP-ribose) polymerase family, member 140.031
Psen1presenilin 10.029
Hoxc4homeo box C40.029
Rps6ka1ribosomal protein S6 kinase polypeptide 10.029
Nek9NIMA (never in mitosis gene a)- related kinase 90.028
Smad3SMAD family member 30.028
Foxe3forkhead box E30.028
Crybb3crystallin, beta B30.027
MrgprfMAS-related GPR, member F0.027
Zc3h11azinc finger CCCH-type containing 11A0.027
Fgf7fibroblast growth factor 70.027
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.026
Foxd3forkhead box D30.026
Rnase1ribonuclease, RNase A family, 1 (pancreatic)0.026
RT1-S3RT1 class Ib, locus S30.025
Prrx1paired related homeobox 10.025
Accn2amiloride-sensitive cation channel 2, neuronal0.024
Smad1SMAD family member 10.024
Gata6GATA binding protein 60.024
Socs3suppressor of cytokine signaling 30.022
Scgb1a1secretoglobin, family 1A, member 1 (uteroglobin)0.022
Lamc1laminin, gamma 10.021
Pde5aphosphodiesterase 5A, cGMP-specific0.021
Ascl1achaete-scute complex homolog 1 (Drosophila)0.021
Chrngcholinergic receptor, nicotinic, gamma0.021
Tgfbr2transforming growth factor, beta receptor II0.020
Slc30a1solute carrier family 30 (zinc transporter), member 10.020
Insrinsulin receptor0.020
Gata3GATA binding protein 30.020
Chmchoroideremia (Rab escort protein 1)0.019
Nos3nitric oxide synthase 3, endothelial cell0.019
Lhx5LIM homeobox 50.019
Pecam1platelet/endothelial cell adhesion molecule 10.019
Cyth3cytohesin 30.019
Pcdhga11protocadherin gamma subfamily A, 110.019
Olr837olfactory receptor 8370.018
Itpr2inositol 1,4,5-triphosphate receptor, type 20.018
BokBCL2-related ovarian killer0.018
Cd80Cd80 molecule0.018
Pdia6protein disulfide isomerase family A, member 60.018
Foxo1forkhead box O10.018
Sp110SP110 nuclear body protein0.017
Jundjun D proto-oncogene0.017
Twist2twist homolog 2 (Drosophila)0.017
Svs4seminal vesicle secretory protein 40.017
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.016
Adam17ADAM metallopeptidase domain 170.016
Pdgfbplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.016
Rab27aRAB27A, member RAS oncogene family0.016
Notch3Notch homolog 3 (Drosophila)0.016
RT1-DOaRT1 class II, locus DOa0.016
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.016
Ednraendothelin receptor type A0.015
Btnl1butyrophilin-like 10.015
Dcaf17DDB1 and CUL4 associated factor 170.015
Hoxa1homeo box A10.015
Elf1E74-like factor 10.015
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.015
Dchs1dachsous 1 (Drosophila)0.014
Skap1src kinase associated phosphoprotein 10.014
Vom1r101vomeronasal 1 receptor 1010.014
Fgf5fibroblast growth factor 50.014
Dock6dedicator of cytokinesis 60.014
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism