IMP
Process View
The network for 'positive regulation of autophagy' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of autophagy
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Atg18 | Autophagy-specific gene 18 | 0.998 | |
| Pi3K59F | Phosphotidylinositol 3 kinase 59F | 0.943 | |
| Atg1 | Autophagy-specific gene 1 | 0.909 | |
| S6k | RPS6-p70-protein kinase | 0.839 | |
| Atg13 | Autophagy-specific gene 13 | 0.796 | |
| Atg8a | Autophagy-specific gene 8a | 0.768 | |
| Dcp-1 | Death caspase-1 | 0.765 | |
| Atg2 | Autophagy-specific gene 2 | 0.756 | |
| Lnk | CG17367 gene product from transcript CG17367-RC | 0.695 | |
| Atg9 | Autophagy-specific gene 9 | 0.668 | |
| Sir2 | CG5216 gene product from transcript CG5216-RA | 0.664 | |
| Pi3K92E | CG4141 gene product from transcript CG4141-RB | 0.617 | |
| car | carnation | 0.589 | |
| grim | CG4345 gene product from transcript CG4345-RA | 0.572 | |
| RASSF8 | CG5053 gene product from transcript CG5053-RA | 0.546 | |
| Mekk1 | CG7717 gene product from transcript CG7717-RB | 0.535 | |
| Atg7 | Autophagy-specific gene 7 | 0.515 | |
| brat | brain tumor | 0.514 | |
| spin | spinster | 0.456 | |
| Sox14 | Sox box protein 14 | 0.391 | |
| ird1 | immune response deficient 1 | 0.354 | |
| debcl | death executioner Bcl-2 homologue | 0.348 | |
| Rel | Relish | 0.303 | |
| Atg4 | Autophagy-specific gene 4 | 0.288 | |
| p38b | CG7393 gene product from transcript CG7393-RA | 0.279 | |
| rpr | reaper | 0.276 | |
| lok | loki | 0.249 | |
| Parp | Poly-(ADP-ribose) polymerase | 0.241 | |
| Akt1 | CG4006 gene product from transcript CG4006-RA | 0.210 | |
| chico | CG5686 gene product from transcript CG5686-RB | 0.201 | |
| th | thread | 0.200 | |
| ari-2 | ariadne 2 | 0.187 | |
| yki | yorkie | 0.185 | |
| wts | warts | 0.176 | |
| Ice | CG7788 gene product from transcript CG7788-RA | 0.174 | |
| Toll-7 | CG8595 gene product from transcript CG8595-RA | 0.159 | |
| Rheb | CG1081 gene product from transcript CG1081-RA | 0.132 | |
| bif | bifocal | 0.124 | |
| X11L | CG5675 gene product from transcript CG5675-RB | 0.097 | |
| BG4 | CG12297 gene product from transcript CG12297-RA | 0.096 | |
| imd | immune deficiency | 0.095 | |
| lmg | lemming | 0.094 | |
| CG31033 | CG31033 gene product from transcript CG31033-RC | 0.088 | |
| egr | eiger | 0.087 | |
| drpr | draper | 0.087 | |
| Toll-6 | CG7250 gene product from transcript CG7250-RA | 0.085 | |
| NFAT | NFAT homolog | 0.083 | |
| CG11877 | CG11877 gene product from transcript CG11877-RA | 0.082 | |
| Eip74EF | Ecdysone-induced protein 74EF | 0.079 | |
| SNF4Agamma | SNF4/AMP-activated protein kinase gamma subunit | 0.079 | |
| kibra | kibra ortholog | 0.076 | |
| cert | ceramide transfer protein | 0.069 | |
| l(3)82Fd | CG32464 gene product from transcript CG32464-RR | 0.063 | |
| dve | defective proventriculus | 0.059 | |
| NT1 | Neurotrophin 1 | 0.059 | |
| AGO2 | Argonaute 2 | 0.057 | |
| Pi3K21B | CG2699 gene product from transcript CG2699-RA | 0.055 | |
| Dab | Disabled | 0.055 | |
| SuUR | Suppressor of Under-Replication | 0.052 | |
| gig | gigas | 0.052 | |
| Mt2 | Methyltransferase 2 | 0.051 | |
| hep | hemipterous | 0.050 | |
| Ark | Apaf-1-related-killer | 0.045 | |
| p53 | CG33336 gene product from transcript CG33336-RB | 0.045 | |
| Traf6 | TNF-receptor-associated factor 6 | 0.045 | |
| sina | seven in absentia | 0.045 | |
| Adf1 | Adh transcription factor 1 | 0.044 | |
| Hrs | Hepatocyte growth factor regulated tyrosine kinase substrate | 0.043 | |
| CG5794 | CG5794 gene product from transcript CG5794-RB | 0.043 | |
| Traf4 | TNF-receptor-associated factor 4 | 0.043 | |
| CG9063 | CG9063 gene product from transcript CG9063-RA | 0.042 | |
| klu | klumpfuss | 0.041 | |
| eyg | eyegone | 0.040 | |
| Myd88 | CG2078 gene product from transcript CG2078-RA | 0.037 | |
| Pink1 | PTEN-induced putative kinase 1 | 0.037 | |
| rin | rasputin | 0.036 | |
| Lis-1 | Lissencephaly-1 | 0.036 | |
| jing | CG9397 gene product from transcript CG9397-RI | 0.035 | |
| Rfabg | Retinoid- and fatty acid-binding glycoprotein | 0.034 | |
| Thor | CG8846 gene product from transcript CG8846-RA | 0.034 | |
| Tip60 | CG6121 gene product from transcript CG6121-RA | 0.033 | |
| Ric | Ras which interacts with Calmodulin | 0.032 | |
| Dfd | Deformed | 0.032 | |
| CG1021 | CG1021 gene product from transcript CG1021-RE | 0.032 | |
| Rpn6 | Proteasome p44.5 subunit | 0.031 | |
| CG12081 | CG12081 gene product from transcript CG12081-RA | 0.030 | |
| Rab7 | Rab-protein 7 | 0.030 | |
| lqfR | liquid facets-Related | 0.030 | |
| CG3589 | CG3589 gene product from transcript CG3589-RA | 0.030 | |
| sim | single-minded | 0.029 | |
| RhoGAP68F | CG6811 gene product from transcript CG6811-RA | 0.028 | |
| sra | sarah | 0.026 | |
| Parg | Poly(ADP-ribose) glycohydrolase | 0.026 | |
| CG18754 | CG18754 gene product from transcript CG18754-RB | 0.026 | |
| TORC | CG6064 gene product from transcript CG6064-RA | 0.025 | |
| CG11534 | CG11534 gene product from transcript CG11534-RA | 0.025 | |
| Eip93F | CG18389 gene product from transcript CG18389-RB | 0.025 | |
| Rac1 | CG2248 gene product from transcript CG2248-RA | 0.025 | |
| trio | CG18214 gene product from transcript CG18214-RA | 0.024 | |
| Syx17 | Syntaxin 17 | 0.024 |
Loading network...
Homo sapiens| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.997 | |
| SQSTM1 | sequestosome 1 | 0.992 | |
| GABARAP | GABA(A) receptor-associated protein | 0.987 | |
| ATG3 | ATG3 autophagy related 3 homolog (S. cerevisiae) | 0.985 | |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.981 | |
| CREBBP | CREB binding protein | 0.971 | |
| TSC2 | tuberous sclerosis 2 | 0.929 | |
| ATG13 | ATG13 autophagy related 13 homolog (S. cerevisiae) | 0.841 | |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit | 0.837 | |
| ATG5 | ATG5 autophagy related 5 homolog (S. cerevisiae) | 0.672 | |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.642 | |
| ATG4B | ATG4 autophagy related 4 homolog B (S. cerevisiae) | 0.566 | |
| AR | androgen receptor | 0.490 | |
| TRIM63 | tripartite motif containing 63 | 0.465 | |
| KAT2B | K(lysine) acetyltransferase 2B | 0.381 | |
| JUN | jun proto-oncogene | 0.365 | |
| GFM1 | G elongation factor, mitochondrial 1 | 0.322 | |
| ULK1 | unc-51-like kinase 1 (C. elegans) | 0.313 | |
| ATG12 | ATG12 autophagy related 12 homolog (S. cerevisiae) | 0.272 | |
| NBR1 | neighbor of BRCA1 gene 1 | 0.234 | |
| SCHIP1 | schwannomin interacting protein 1 | 0.224 | |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.212 | |
| FOXO3 | forkhead box O3 | 0.201 | |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.185 | |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.182 | |
| MAPK8 | mitogen-activated protein kinase 8 | 0.173 | |
| TSC1 | tuberous sclerosis 1 | 0.170 | |
| BAD | BCL2-associated agonist of cell death | 0.167 | |
| NCOA1 | nuclear receptor coactivator 1 | 0.167 | |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.160 | |
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.155 | |
| S100B | S100 calcium binding protein B | 0.140 | |
| NCOA2 | nuclear receptor coactivator 2 | 0.136 | |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.115 | |
| TFRC | transferrin receptor (p90, CD71) | 0.111 | |
| ARNT | aryl hydrocarbon receptor nuclear translocator | 0.110 | |
| MAP1LC3A | microtubule-associated protein 1 light chain 3 alpha | 0.109 | |
| ACACA | acetyl-CoA carboxylase alpha | 0.107 | |
| ATG16L1 | ATG16 autophagy related 16-like 1 (S. cerevisiae) | 0.104 | |
| ARRB1 | arrestin, beta 1 | 0.093 | |
| MRPL41 | mitochondrial ribosomal protein L41 | 0.086 | |
| EP300 | E1A binding protein p300 | 0.081 | |
| OTUD6B | OTU domain containing 6B | 0.080 | |
| FOXO1 | forkhead box O1 | 0.078 | |
| TTN | titin | 0.075 | |
| EGLN1 | egl nine homolog 1 (C. elegans) | 0.070 | |
| SESN2 | sestrin 2 | 0.068 | |
| COASY | CoA synthase | 0.064 | |
| PINK1 | PTEN induced putative kinase 1 | 0.064 | |
| NCOA6 | nuclear receptor coactivator 6 | 0.064 | |
| DAPK1 | death-associated protein kinase 1 | 0.063 | |
| ATG7 | ATG7 autophagy related 7 homolog (S. cerevisiae) | 0.060 | |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.053 | |
| VHL | von Hippel-Lindau tumor suppressor | 0.049 | |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.049 | |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 0.048 | |
| SIRT1 | sirtuin 1 | 0.047 | |
| ATG14 | ATG14 autophagy related 14 homolog (S. cerevisiae) | 0.045 | |
| NEB | nebulin | 0.045 | |
| EGLN3 | egl nine homolog 3 (C. elegans) | 0.044 | |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.044 | |
| RUNX1 | runt-related transcription factor 1 | 0.039 | |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.038 | |
| HDAC5 | histone deacetylase 5 | 0.038 | |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.036 | |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | 0.035 | |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.035 | |
| CIZ1 | CDKN1A interacting zinc finger protein 1 | 0.035 | |
| PIK3C3 | phosphoinositide-3-kinase, class 3 | 0.035 | |
| PRKAB1 | protein kinase, AMP-activated, beta 1 non-catalytic subunit | 0.035 | |
| NFE2L2 | nuclear factor (erythroid-derived 2)-like 2 | 0.033 | |
| TP53BP2 | tumor protein p53 binding protein, 2 | 0.033 | |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.032 | |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.031 | |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.031 | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.030 | |
| SMAD3 | SMAD family member 3 | 0.030 | |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.030 | |
| BCL2L1 | BCL2-like 1 | 0.029 | |
| BCL2 | B-cell CLL/lymphoma 2 | 0.028 | |
| IRS2 | insulin receptor substrate 2 | 0.026 | |
| HDAC4 | histone deacetylase 4 | 0.026 | |
| KDM2A | lysine (K)-specific demethylase 2A | 0.026 | |
| STBD1 | starch binding domain 1 | 0.025 | |
| CRTC2 | CREB regulated transcription coactivator 2 | 0.024 | |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 | 0.024 | |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.024 | |
| FAM190B | family with sequence similarity 190, member B | 0.024 | |
| MYOZ1 | myozenin 1 | 0.023 | |
| GET4 | golgi to ER traffic protein 4 homolog (S. cerevisiae) | 0.023 | |
| EXOC8 | exocyst complex component 8 | 0.023 | |
| OPTN | optineurin | 0.023 | |
| IRF3 | interferon regulatory factor 3 | 0.023 | |
| TCAP | titin-cap (telethonin) | 0.022 | |
| ZFYVE1 | zinc finger, FYVE domain containing 1 | 0.021 | |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.021 | |
| FNIP1 | folliculin interacting protein 1 | 0.021 | |
| UVRAG | UV radiation resistance associated gene | 0.021 | |
| NF2 | neurofibromin 2 (merlin) | 0.020 | |
| DAZAP2 | DAZ associated protein 2 | 0.020 |
Loading network...
Mus musculus| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Pten | phosphatase and tensin homolog | 0.987 | |
| Mapk8ip3 | mitogen-activated protein kinase 8 interacting protein 3 | 0.763 | |
| Tsc2 | tuberous sclerosis 2 | 0.664 | |
| Tsc1 | tuberous sclerosis 1 | 0.505 | |
| Rb1 | retinoblastoma 1 | 0.338 | |
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.320 | |
| Nf2 | neurofibromatosis 2 | 0.280 | |
| Atf2 | activating transcription factor 2 | 0.269 | |
| Mapk14 | mitogen-activated protein kinase 14 | 0.239 | |
| Mapk8 | mitogen-activated protein kinase 8 | 0.228 | |
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.207 | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.201 | |
| Sesn2 | sestrin 2 | 0.187 | |
| Cftr | cystic fibrosis transmembrane conductance regulator homolog | 0.175 | |
| Foxa2 | forkhead box A2 | 0.166 | |
| Vhl | von Hippel-Lindau tumor suppressor | 0.138 | |
| Pim2 | proviral integration site 2 | 0.133 | |
| Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.128 | |
| Egln1 | EGL nine homolog 1 (C. elegans) | 0.125 | |
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.119 | |
| Sqstm1 | sequestosome 1 | 0.099 | |
| Atg13 | ATG13 autophagy related 13 homolog (S. cerevisiae) | 0.093 | |
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.087 | |
| Lepr | leptin receptor | 0.074 | |
| Prkag1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 0.068 | |
| Socs1 | suppressor of cytokine signaling 1 | 0.066 | |
| Ywhag | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.066 | |
| Gsk3b | glycogen synthase kinase 3 beta | 0.051 | |
| Rint1 | RAD50 interactor 1 | 0.048 | |
| Prkab1 | protein kinase, AMP-activated, beta 1 non-catalytic subunit | 0.048 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.047 | |
| Apc | adenomatosis polyposis coli | 0.047 | |
| Ulk1 | Unc-51 like kinase 1 (C. elegans) | 0.046 | |
| Cdc42 | cell division cycle 42 homolog (S. cerevisiae) | 0.045 | |
| Igbp1 | immunoglobulin (CD79A) binding protein 1 | 0.045 | |
| Pim1 | proviral integration site 1 | 0.042 | |
| Keap1 | kelch-like ECH-associated protein 1 | 0.041 | |
| Dmap1 | DNA methyltransferase 1-associated protein 1 | 0.041 | |
| Mark4 | MAP/microtubule affinity-regulating kinase 4 | 0.039 | |
| Gopc | golgi associated PDZ and coiled-coil motif containing | 0.038 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.038 | |
| Ikbkg | inhibitor of kappaB kinase gamma | 0.037 | |
| Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | 0.037 | |
| Pik3c3 | phosphoinositide-3-kinase, class 3 | 0.035 | |
| Rora | RAR-related orphan receptor alpha | 0.032 | |
| Zbtb24 | zinc finger and BTB domain containing 24 | 0.032 | |
| Arid1b | AT rich interactive domain 1B (SWI-like) | 0.030 | |
| Sav1 | salvador homolog 1 (Drosophila) | 0.029 | |
| Hbb-b1 | hemoglobin, beta adult major chain | 0.029 | |
| Epor | erythropoietin receptor | 0.029 | |
| Foxa1 | forkhead box A1 | 0.028 | |
| Rxra | retinoid X receptor alpha | 0.028 | |
| Atg12 | autophagy-related 12 (yeast) | 0.028 | |
| Errfi1 | ERBB receptor feedback inhibitor 1 | 0.028 | |
| Foxo1 | forkhead box O1 | 0.026 | |
| Prkce | protein kinase C, epsilon | 0.024 | |
| Atxn1 | ataxin 1 | 0.024 | |
| Ticam1 | toll-like receptor adaptor molecule 1 | 0.023 | |
| Clock | circadian locomotor output cycles kaput | 0.023 | |
| Arntl | aryl hydrocarbon receptor nuclear translocator-like | 0.023 | |
| Klc1 | kinesin light chain 1 | 0.022 | |
| Cdx2 | caudal type homeobox 2 | 0.021 | |
| Grb2 | growth factor receptor bound protein 2 | 0.021 | |
| Hbb-b2 | hemoglobin, beta adult minor chain | 0.020 | |
| Nkx2-1 | NK2 homeobox 1 | 0.019 | |
| Xpa | xeroderma pigmentosum, complementation group A | 0.019 | |
| Mapkbp1 | mitogen-activated protein kinase binding protein 1 | 0.018 | |
| Mecp2 | methyl CpG binding protein 2 | 0.018 | |
| Axin1 | axin 1 | 0.018 | |
| Bsdc1 | BSD domain containing 1 | 0.017 | |
| Mapk1 | mitogen-activated protein kinase 1 | 0.017 | |
| P4htm | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 0.016 | |
| Ppp3ca | protein phosphatase 3, catalytic subunit, alpha isoform | 0.016 | |
| Dmtf1 | cyclin D binding myb-like transcription factor 1 | 0.015 | |
| Chmp1b | chromatin modifying protein 1B | 0.015 | |
| Pdpk1 | 3-phosphoinositide dependent protein kinase 1 | 0.015 | |
| Msh2 | mutS homolog 2 (E. coli) | 0.015 | |
| Htatip2 | HIV-1 tat interactive protein 2, homolog (human) | 0.015 | |
| Pim3 | proviral integration site 3 | 0.014 | |
| Mib1 | mindbomb homolog 1 (Drosophila) | 0.014 | |
| Rfwd2 | ring finger and WD repeat domain 2 | 0.014 | |
| Gabarapl1 | gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1 | 0.013 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.013 | |
| Egln3 | EGL nine homolog 3 (C. elegans) | 0.012 | |
| Sox9 | SRY-box containing gene 9 | 0.012 | |
| Nbr1 | neighbor of Brca1 gene 1 | 0.012 | |
| E2f1 | E2F transcription factor 1 | 0.012 | |
| Ep300 | E1A binding protein p300 | 0.012 | |
| Rbl1 | retinoblastoma-like 1 (p107) | 0.011 | |
| Stat6 | signal transducer and activator of transcription 6 | 0.011 | |
| Ep400 | E1A binding protein p400 | 0.011 | |
| Ubc | ubiquitin C | 0.011 | |
| Dnm1l | dynamin 1-like | 0.011 | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.011 | |
| Cdh1 | cadherin 1 | 0.011 | |
| Rbl2 | retinoblastoma-like 2 | 0.011 | |
| Yap1 | yes-associated protein 1 | 0.010 | |
| Rb1cc1 | RB1-inducible coiled-coil 1 | 0.010 | |
| Ptp4a2 | protein tyrosine phosphatase 4a2 | 0.010 | |
| Braf | Braf transforming gene | 0.010 |