The network for 'reactive nitrogen species metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

reactive nitrogen species metabolic process

The chemical reactions and pathways involving a reactive nitrogen species.

NameDescriptionProbabilityFunc Analog Organism
gemininCG3183 gene product from transcript CG3183-RA0.016
d4CG2682 gene product from transcript CG2682-RB0.012
ctpcut up0.011
SetCG4299 gene product from transcript CG4299-RA0.011
BEAF-32Boundary element-associated factor of 32kD0.011
IncenpInner centromere protein0.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
chrna1cholinergic receptor, nicotinic, alpha polypeptide 10.756
myhz2myosin, heavy polypeptide 2, fast muscle specific0.625
stc1lstanniocalcin 1, like0.608
tnnc1btroponin C type 1b (slow)0.525
hsp90a.1heat shock protein 90-alpha 10.484
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.463
tnnt3atroponin T3a, skeletal, fast0.461
vangl2vang-like 2 (van gogh, Drosophila)0.396
gcm2glial cells missing homolog 2 (Drosophila)0.393
smyhc1lslow myosin heavy chain 1, like0.383
acta1aactin, alpha 1a, skeletal muscle0.378
LOC799612prolactin 20.348
tlr18toll-like receptor 180.302
scribscribbled homolog (Drosophila)0.265
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.257
hspa4aheat shock protein 4a0.247
tnnc2troponin C type 2 (fast)0.233
tnnt3btroponin T3b, skeletal, fast0.223
nos2bnitric oxide synthase 2b, inducible0.213
ifnphi1interferon phi 10.200
ryr1bryanodine receptor 1b (skeletal)0.183
tlr3toll-like receptor 30.162
cav1caveolin 10.158
insrbinsulin receptor b0.157
relv-rel reticuloendotheliosis viral oncogene homolog0.154
sod1superoxide dismutase 1, soluble0.152
myl1myosin, light chain 1, alkali; skeletal, fast0.145
lamb2laminin, beta 2 (laminin S)0.145
furinbfurin (paired basic amino acid cleaving enzyme) b0.140
bonbonnie and clyde0.136
mylz2myosin, light polypeptide 2, skeletal muscle0.130
atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.129
elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast)0.122
plxnb2aplexin b2a0.118
myhc4myosin heavy chain 40.115
shmt2serine hydroxymethyltransferase 2 (mitochondrial)0.114
abcc1ATP-binding cassette, sub-family C, member 10.113
insrainsulin receptor a0.113
ckmacreatine kinase, muscle a0.113
nos2anitric oxide synthase 2a, inducible0.109
pgm1phosphoglucomutase 10.109
rbfox1lRNA binding protein, fox-1 homolog (C. elegans) 1-like0.107
ca8carbonic anhydrase VIII0.105
cx39.9connexin 39.90.104
tnfatumor necrosis factor a (TNF superfamily, member 2)0.104
plcg1phospholipase C, gamma 10.103
fabp11afatty acid binding protein 11a0.103
myhz1.2myosin, heavy polypeptide 1.2, skeletal muscle0.103
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.101
tnnt1troponin T1, skeletal, slow0.101
tp53bp2tumor protein p53 binding protein, 20.100
pth1aparathyroid hormone 1a0.096
trpv6transient receptor potential cation channel, subfamily V, member 60.093
il8interleukin 80.093
s100a10bS100 calcium binding protein A10b0.092
ptger4bprostaglandin E receptor 4 (subtype EP4) b0.091
tpm3tropomyosin 30.088
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.084
rag1recombination activating gene 10.081
slc25a14solute carrier family 25 (mitochondrial carrier, brain), member 140.080
pdcd4bprogrammed cell death 4b0.079
ckmbcreatine kinase, muscle b0.079
col10a1collagen, type X, alpha 10.078
nrg1neuregulin 10.078
hcrthypocretin (orexin) neuropeptide precursor0.078
s100bS100 calcium binding protein, beta (neural)0.078
elovl2elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 20.076
xirp1xin actin-binding repeat containing 10.076
mef2camyocyte enhancer factor 2ca0.076
unc45bunc-45 homolog B (C. elegans)0.075
jam2ajunctional adhesion molecule 2a0.073
LOC560602novel protein similar to vertebrate solute carrier family 2 (facilitated glucose transporter), member 6 (SLC2A6)0.072
hspb1heat shock protein, alpha-crystallin-related, 10.071
il6rinterleukin 6 receptor0.067
tnni2a.4troponin I, skeletal, fast 2a.40.066
smyhc1slow myosin heavy chain 10.065
pink1PTEN induced putative kinase 10.065
park7parkinson disease (autosomal recessive, early onset) 70.065
slc2a1asolute carrier family 2 (facilitated glucose transporter), member 1a0.065
tph2tryptophan hydroxylase 2 (tryptophan 5-monooxygenase)0.064
pou1f1POU domain, class 1, transcription factor 10.063
acvr1bactivin A receptor, type IB0.062
stac3SH3 and cysteine rich domain 30.062
flncbfilamin C, gamma b (actin binding protein 280)0.061
LOC100149148novel protein similar to myosin heavy chain 4 (myhc4)0.060
ripk2receptor-interacting serine-threonine kinase 20.060
adora2abadenosine A2a receptor b0.060
tecrbtrans-2,3-enoyl-CoA reductase b0.058
kcnh2potassium voltage-gated channel, subfamily H (eag-related), member 20.058
ptgs2aprostaglandin-endoperoxide synthase 2a0.057
myod1myogenic differentiation 10.057
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor1.000
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.999
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.995
TNFAIP3tumor necrosis factor, alpha-induced protein 30.992
IL1R1interleukin 1 receptor, type I0.955
IL8interleukin 80.914
NOSTRINnitric oxide synthase trafficker0.888
ESR1estrogen receptor 10.880
MYD88myeloid differentiation primary response gene (88)0.865
PTPN1protein tyrosine phosphatase, non-receptor type 10.834
IRAK2interleukin-1 receptor-associated kinase 20.816
INSRinsulin receptor0.756
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.738
KLF6Kruppel-like factor 60.721
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.716
NFKBIZnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta0.686
STAT5Asignal transducer and activator of transcription 5A0.683
KLF4Kruppel-like factor 4 (gut)0.660
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.642
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.629
BCAR1breast cancer anti-estrogen resistance 10.629
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.624
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.623
DERL1Der1-like domain family, member 10.560
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.528
TICAM2toll-like receptor adaptor molecule 20.515
VAC14Vac14 homolog (S. cerevisiae)0.499
DLG2discs, large homolog 2 (Drosophila)0.480
ZC3H12Azinc finger CCCH-type containing 12A0.453
NOXA1NADPH oxidase activator 10.452
SH2D1ASH2 domain containing 1A0.449
BCL3B-cell CLL/lymphoma 30.427
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.421
IL10RAinterleukin 10 receptor, alpha0.418
IGF1Rinsulin-like growth factor 1 receptor0.412
JUNBjun B proto-oncogene0.408
HERPUD1homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 10.388
GRB10growth factor receptor-bound protein 100.375
LCKlymphocyte-specific protein tyrosine kinase0.372
TNIP2TNFAIP3 interacting protein 20.368
DUSP1dual specificity phosphatase 10.338
ANKS1Bankyrin repeat and sterile alpha motif domain containing 1B0.337
GAB1GRB2-associated binding protein 10.326
CCL20chemokine (C-C motif) ligand 200.316
FYNFYN oncogene related to SRC, FGR, YES0.313
PKD1polycystic kidney disease 1 (autosomal dominant)0.309
FOSL2FOS-like antigen 20.305
DDR2discoidin domain receptor tyrosine kinase 20.295
CALCAcalcitonin-related polypeptide alpha0.293
JUNjun proto-oncogene0.275
SOCS3suppressor of cytokine signaling 30.274
IRF1interferon regulatory factor 10.265
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.262
PPP5Cprotein phosphatase 5, catalytic subunit0.258
FOSFBJ murine osteosarcoma viral oncogene homolog0.255
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.247
PECAM1platelet/endothelial cell adhesion molecule0.247
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.244
MAPTmicrotubule-associated protein tau0.244
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.242
TRPC1transient receptor potential cation channel, subfamily C, member 10.239
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.237
MPDZmultiple PDZ domain protein0.236
PRKCDprotein kinase C, delta0.235
IER3immediate early response 30.235
MATKmegakaryocyte-associated tyrosine kinase0.233
SMAD3SMAD family member 30.232
TNIP1TNFAIP3 interacting protein 10.213
MYLK2myosin light chain kinase 20.212
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.210
PTPN6protein tyrosine phosphatase, non-receptor type 60.210
ALDOBaldolase B, fructose-bisphosphate0.207
NTRK1neurotrophic tyrosine kinase, receptor, type 10.207
RHOBras homolog gene family, member B0.205
SMURF1SMAD specific E3 ubiquitin protein ligase 10.203
LATlinker for activation of T cells0.196
GHRgrowth hormone receptor0.195
IRS1insulin receptor substrate 10.195
CDCP1CUB domain containing protein 10.189
CSF2RBcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.181
PTPRZ1protein tyrosine phosphatase, receptor-type, Z polypeptide 10.175
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.174
MAP2K4mitogen-activated protein kinase kinase 40.173
PPP1R15Aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.167
MAP3K8mitogen-activated protein kinase kinase kinase 80.159
CDC37cell division cycle 37 homolog (S. cerevisiae)0.155
DLG1discs, large homolog 1 (Drosophila)0.155
JAK3Janus kinase 30.154
IL1R2interleukin 1 receptor, type II0.149
ZNF71zinc finger protein 710.149
LY96lymphocyte antigen 960.149
BIRC3baculoviral IAP repeat containing 30.144
EPORerythropoietin receptor0.142
MAFFv-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)0.140
PRKCZprotein kinase C, zeta0.139
NR0B2nuclear receptor subfamily 0, group B, member 20.138
SSTR2somatostatin receptor 20.137
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.136
SRCIN1SRC kinase signaling inhibitor 10.134
IL1Binterleukin 1, beta0.124
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Tlr4toll-like receptor 40.997
Mmp9matrix metallopeptidase 90.991
Tnftumor necrosis factor0.978
Leprleptin receptor0.968
Lyz2lysozyme 20.960
Ppargperoxisome proliferator activated receptor gamma0.942
Nos2nitric oxide synthase 2, inducible0.942
Ccl2chemokine (C-C motif) ligand 20.930
H2-K1histocompatibility 2, K1, K region0.924
H2-D1histocompatibility 2, D region locus 10.924
Il10interleukin 100.908
B2mbeta-2 microglobulin0.901
Klra9killer cell lectin-like receptor subfamily A, member 90.898
Tlr2toll-like receptor 20.863
Vdrvitamin D receptor0.860
Ccr2chemokine (C-C motif) receptor 20.822
Cav1caveolin 1, caveolae protein0.806
Myd88myeloid differentiation primary response gene 880.794
Apoeapolipoprotein E0.783
Tgfb1transforming growth factor, beta 10.781
Ptgs2prostaglandin-endoperoxide synthase 20.720
Nos3nitric oxide synthase 3, endothelial cell0.693
Nos1nitric oxide synthase 1, neuronal0.687
Ren1renin 1 structural0.680
Il1ainterleukin 1 alpha0.654
Ptenphosphatase and tensin homolog0.642
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.630
Atxn1ataxin 10.602
H2-Q7histocompatibility 2, Q region locus 70.582
Stat3signal transducer and activator of transcription 30.569
Casp4caspase 4, apoptosis-related cysteine peptidase0.533
Dmddystrophin, muscular dystrophy0.524
Il6interleukin 60.511
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.474
Ncr1natural cytotoxicity triggering receptor 10.450
Ghrgrowth hormone receptor0.443
Smad3MAD homolog 3 (Drosophila)0.439
Cd44CD44 antigen0.390
Chordc1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 10.376
Cd14CD14 antigen0.375
Il7rinterleukin 7 receptor0.367
Klrb1bkiller cell lectin-like receptor subfamily B member 1B0.333
Rag1recombination activating gene 10.330
Col1a1collagen, type I, alpha 10.318
Insrinsulin receptor0.314
H2-Aahistocompatibility 2, class II antigen A, alpha0.310
Ccr6chemokine (C-C motif) receptor 60.309
Klrk1killer cell lectin-like receptor subfamily K, member 10.307
Gzmagranzyme A0.307
Asap1ArfGAP with SH# domain, ankyrin repeat and PH domain10.277
Adora3adenosine A3 receptor0.277
Il2rginterleukin 2 receptor, gamma chain0.271
Gzmkgranzyme K0.261
FaslFas ligand (TNF superfamily, member 6)0.255
Casp1caspase 10.252
Arandrogen receptor0.241
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.239
Nr3c1nuclear receptor subfamily 3, group C, member 10.235
Ptrfpolymerase I and transcript release factor0.234
Gcet2germinal center expressed transcript 20.233
Map3k8mitogen-activated protein kinase kinase kinase 80.231
Prnpprion protein0.227
Emr1EGF-like module containing, mucin-like, hormone receptor-like sequence 10.226
F9coagulation factor IX0.226
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.223
Bcar1breast cancer anti-estrogen resistance 10.221
Ptprcprotein tyrosine phosphatase, receptor type, C0.220
H2-Q6histocompatibility 2, Q region locus 60.219
Esr1estrogen receptor 1 (alpha)0.215
Pilrb1paired immunoglobin-like type 2 receptor beta 10.215
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.199
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.199
Itgb3integrin beta 30.193
Vhlvon Hippel-Lindau tumor suppressor0.189
Csf1colony stimulating factor 1 (macrophage)0.184
Itgb1integrin beta 1 (fibronectin receptor beta)0.181
Ccr3chemokine (C-C motif) receptor 30.180
Fpr3formyl peptide receptor 30.179
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.172
Socs1suppressor of cytokine signaling 10.172
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.170
Fpr1formyl peptide receptor 10.170
Meox2mesenchyme homeobox 20.169
FasFas (TNF receptor superfamily member 6)0.167
Spp1secreted phosphoprotein 10.167
Lair1leukocyte-associated Ig-like receptor 10.165
Clec4nC-type lectin domain family 4, member n0.165
Il1r1interleukin 1 receptor, type I0.163
Agtr1aangiotensin II receptor, type 1a0.162
P2rx2purinergic receptor P2X, ligand-gated ion channel, 20.159
F7coagulation factor VII0.159
Adam23a disintegrin and metallopeptidase domain 230.156
Aoahacyloxyacyl hydrolase0.155
SrcRous sarcoma oncogene0.155
Mapk14mitogen-activated protein kinase 140.154
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ccl2chemokine (C-C motif) ligand 20.111
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.105
Rup2urinary protein 20.099
Procprotein C0.073
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.070
Cxcl2chemokine (C-X-C motif) ligand 20.070
Abcc6ATP-binding cassette, subfamily C (CFTR/MRP), member 60.070
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.069
Mbl1mannose-binding lectin (protein A) 10.069
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.068
Il1rl1interleukin 1 receptor-like 10.066
Fgafibrinogen alpha chain0.066
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.064
Eef2eukaryotic translation elongation factor 20.064
Slco2a1solute carrier organic anion transporter family, member 2a10.063
Mmp12matrix metallopeptidase 120.063
Pfkfb16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 10.061
Hist1h1ahistone cluster 1, H1a0.060
Orm1orosomucoid 10.060
Aqp9aquaporin 90.059
Hspb1heat shock protein 10.058
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.056
Srd5a1steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)0.056
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.054
TifaTRAF-interacting protein with forkhead-associated domain0.054
Nr4a3nuclear receptor subfamily 4, group A, member 30.054
S100a6S100 calcium binding protein A60.054
Cd151CD151 molecule (Raph blood group)0.054
Il1rninterleukin 1 receptor antagonist0.053
Sdc3syndecan 30.053
Hk1hexokinase 10.052
Cxcl16chemokine (C-X-C motif) ligand 160.052
Edn1endothelin 10.051
Scn8asodium channel, voltage gated, type VIII, alpha subunit0.051
C8bcomplement component 8, beta polypeptide0.051
Grm7glutamate receptor, metabotropic 70.051
Tpbpatrophoblast specific protein alpha0.051
Mst1Macrophage stimulating 1 (hepatocyte growth factor-like)0.050
Rab1bRAB1B, member RAS oncogene family0.050
Cpb1carboxypeptidase B1 (tissue)0.050
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.050
Htr1f5-hydroxytryptamine (serotonin) receptor 1F0.049
Dccdeleted in colorectal carcinoma0.048
Prss1protease, serine, 1 (trypsin 1)0.046
Zfp36l1zinc finger protein 36, C3H type-like 10.046
Cpb2carboxypeptidase B2 (plasma)0.046
Prl2a1Prolactin family 2, subfamily a, member 10.046
Ccl4chemokine (C-C motif) ligand 40.045
Il1binterleukin 1 beta0.045
Tgfb1transforming growth factor, beta 10.045
Il18interleukin 180.044
Cx3cl1chemokine (C-X3-C motif) ligand 10.044
Prkcdprotein kinase C, delta0.043
Cd3gCD3 molecule, gamma0.043
LOC100360019hypothetical protein LOC1003600190.043
Cyp2a2cytochrome P450, family 2, subfamily a, polypeptide 20.043
Cd14CD14 molecule0.043
Arl5cADP-ribosylation factor-like 5C0.043
Tff3trefoil factor 3, intestinal0.042
Syt4synaptotagmin IV0.042
Agtr1aangiotensin II receptor, type 1a0.042
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.042
LOC687856similar to Myeloid cell surface antigen CD33 precursor (Siglec-3)0.041
Itgalintegrin, alpha L0.041
Acsm5acyl-CoA synthetase medium-chain family member 50.041
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.040
Serpina3mserine (or cysteine) proteinase inhibitor, clade A, member 3M0.040
Il2rginterleukin 2 receptor, gamma0.040
Spp2secreted phosphoprotein 20.040
Il4rainterleukin 4 receptor, alpha0.039
Pkiaprotein kinase (cAMP-dependent, catalytic) inhibitor alpha0.039
JunJun oncogene0.039
Cd52CD52 antigen0.039
Anxa5annexin A50.039
Grm8glutamate receptor, metabotropic 80.039
Srd5a2steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)0.038
Gna12guanine nucleotide binding protein (G protein) alpha 120.038
Tnfrsf11aTumor necrosis factor receptor superfamily, member 11a0.038
Slco1b3solute carrier organic anion transporter family, member 1b30.037
Rasgrp1RAS guanyl releasing protein 1 (calcium and DAG-regulated)0.037
Lgals3lectin, galactoside-binding, soluble, 30.037
Odf3bouter dense fiber of sperm tails 3B0.037
Pahphenylalanine hydroxylase0.037
Fam38afamily with sequence similarity 38, member A0.037
Cyp2c7cytochrome P450, family 2, subfamily c, polypeptide 70.037
Dlgap1discs, large (Drosophila) homolog-associated protein 10.037
Gifgastric intrinsic factor0.037
Gpr1G protein-coupled receptor 10.036
Nek9NIMA (never in mitosis gene a)- related kinase 90.036
Apoa2apolipoprotein A-II0.036
C3complement component 30.036
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.036
Gulogulonolactone (L-) oxidase0.036
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism