The network for 'response to oxidative stress' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to oxidative stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

NameDescriptionProbabilityFunc Analog Organism
SodSuperoxide dismutase1.000
Trx-2thioredoxin-20.998
CatCatalase0.997
Sod2Superoxide dismutase 2 (Mn)0.987
MTF-1Metal response element-binding Transcription Factor-10.980
Mpk2CG5475 gene product from transcript CG5475-RB0.977
Pink1PTEN-induced putative kinase 10.975
p38bCG7393 gene product from transcript CG7393-RA0.959
shishibire0.946
NLazNeural Lazarillo0.933
PHGPxCG12013 gene product from transcript CG12013-RC0.910
SdhBSuccinate dehydrogenase B0.906
l(3)82FdCG32464 gene product from transcript CG32464-RR0.905
Jafrac1thioredoxin peroxidase 10.885
mthmethuselah0.881
drkdownstream of receptor kinase0.857
CG6783CG6783 gene product from transcript CG6783-RC0.846
InRInsulin-like receptor0.825
dj-1betaCG1349 gene product from transcript CG1349-RA0.747
TpiTriose phosphate isomerase0.731
Prx5Peroxiredoxin 50.723
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.721
dcodiscs overgrown0.695
p120ctnAdherens junction protein p1200.661
benbendless0.642
chicoCG5686 gene product from transcript CG5686-RB0.607
MerMerlin0.601
Gyc-89DaGuanylyl cyclase at 89Da0.599
C3GCG42328 gene product from transcript CG42328-RC0.578
ThorCG8846 gene product from transcript CG8846-RA0.568
staistathmin0.567
lokloki0.566
Atf-2Activating transcription factor-20.547
Pi3K68DPhosphotidylinositol 3 kinase 68D0.517
mei-41meiotic 410.513
Dcr-2Dicer-20.498
tefutelomere fusion0.495
certceramide transfer protein0.487
MAN1CG3167 gene product from transcript CG3167-RA0.483
CG5362CG5362 gene product from transcript CG5362-RA0.473
GLazGlial Lazarillo0.464
wtswarts0.449
Trxr-1Thioredoxin reductase-10.447
AldhAldehyde dehydrogenase0.442
Atg13Autophagy-specific gene 130.410
panpangolin0.407
kermitCG11546 gene product from transcript CG11546-RB0.389
shgshotgun0.385
Hsp27Heat shock protein 270.380
ttan0.373
Mekk1CG7717 gene product from transcript CG7717-RB0.366
Vps4Vacuolar protein sorting 40.346
keykenny0.344
rdgBretinal degeneration B0.341
ImpL2Ecdysone-inducible gene L20.331
LnkCG17367 gene product from transcript CG17367-RC0.327
SnooSno oncogene0.327
Hsp22Heat shock protein 220.326
awdabnormal wing discs0.323
Akt1CG4006 gene product from transcript CG4006-RA0.315
mus201mutagen-sensitive 2010.311
fzyfizzy0.304
Gyc-89DbGuanylyl cyclase at 89Db0.302
hephemipterous0.300
DreddDeath related ced-3/Nedd2-like protein0.289
EcREcdysone receptor0.283
Ca-P60ACalcium ATPase at 60A0.282
Trap1CG3152 gene product from transcript CG3152-RA0.272
sevsevenless0.268
eagether a go-go0.267
CG8036CG8036 gene product from transcript CG8036-RB0.266
DabDisabled0.257
p53CG33336 gene product from transcript CG33336-RB0.249
CG13604CG13604 gene product from transcript CG13604-RD0.246
CG8993CG8993 gene product from transcript CG8993-RA0.246
CngCyclic-nucleotide-gated ion channel protein0.243
RicRas which interacts with Calmodulin0.242
IndyI'm not dead yet0.241
Rac1CG2248 gene product from transcript CG2248-RA0.241
CG3683CG3683 gene product from transcript CG3683-RC0.239
Eip71CDEcdysone-induced protein 28/29kD0.227
mus209mutagen-sensitive 2090.227
foxoforkhead box, sub-group O0.222
Act57BActin 57B0.216
maf-SCG9954 gene product from transcript CG9954-RA0.216
Hsp68Heat shock protein 680.215
CrebB-17ACyclic-AMP response element binding protein B at 17A0.215
bvesCG32513 gene product from transcript CG32513-RA0.214
AnnXAnnexin X0.213
Lectin-galC1Galactose-specific C-type lectin0.212
G-salpha60AG protein salpha 60A0.212
Tsp42EfTetraspanin 42Ef0.210
Ras85DRas oncogene at 85D0.201
CG42630CG42630 gene product from transcript CG42630-RA0.197
rheaCG6831 gene product from transcript CG6831-RA0.197
cln3CG5582 gene product from transcript CG5582-RA0.196
giggigas0.195
l(3)L1231lethal (3) L12310.191
SosSon of sevenless0.187
dncdunce0.179
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
itr-1Protein ITR-10.038
acdh-3Protein ACDH-30.035
mat-3Protein MAT-30.035
K11H12.8Protein K11H12.80.029
ppk-3Protein PPK-30.029
hlh-2Protein HLH-20.025
nhr-67Protein NHR-670.024
bath-42Protein BATH-420.022
lpin-1Protein LPIN-10.022
gsr-1Protein GSR-10.021
zyg-8Protein ZYG-80.021
sem-5Protein SEM-50.021
cye-1Protein CYE-10.021
cri-3Protein CRI-30.021
F35G2.2Protein F35G2.20.020
cat-1Protein CAT-10.020
tomm-20Protein TOMM-200.019
pek-1Protein PEK-10.019
nhr-34Protein NHR-340.019
gst-7Protein GST-70.019
gei-4Protein GEI-40.018
Y22D7AL.10Protein Y22D7AL.100.018
CELE_C27D8.2Protein C27D8.20.018
prdx-2Protein PRDX-20.018
egl-18Protein EGL-180.018
cam-1Protein CAM-10.018
vav-1Protein VAV-10.018
K07C11.4Protein K07C11.40.018
W01A11.1Protein W01A11.10.017
prdx-3Protein PRDX-30.017
let-60Protein LET-600.017
nhr-120Protein NHR-1200.017
C18B2.5Protein C18B2.50.017
vps-16Protein VPS-160.017
pdfr-1Protein PDFR-10.017
pes-1Protein PES-10.017
smf-3Protein SMF-30.016
vrk-1Protein VRK-10.016
ubr-1Protein UBR-10.016
egl-8Protein EGL-80.016
har-1Protein HAR-10.016
F48E8.3Protein F48E8.30.016
pmk-1Protein PMK-10.016
mrp-1Protein MRP-10.016
F43H9.4Protein F43H9.40.016
T23F4.2Protein T23F4.20.015
smf-2Protein SMF-20.015
mpz-2Protein MPZ-20.015
F33H2.3Protein F33H2.30.015
npp-13Protein NPP-130.015
bli-4Protein BLI-40.015
gei-8Protein GEI-80.015
C34F6.10Protein C34F6.100.015
E04A4.5Protein E04A4.50.015
cin-4Protein CIN-40.015
ZC449.5Protein ZC449.50.015
eat-16Protein EAT-160.015
hlh-1Protein HLH-10.015
apa-2Protein APA-20.015
eif-3.KProtein EIF-3.K0.014
rpia-1Protein RPIA-10.014
hlh-14Protein HLH-140.014
lpd-9Protein LPD-90.014
F21A10.2Protein F21A10.20.014
sym-4Protein SYM-40.014
T08G11.1Protein T08G11.10.014
nuo-2Protein NUO-20.014
R05F9.6Protein R05F9.60.014
CELE_F20D1.3Protein F20D1.30.014
fln-2Protein FLN-20.014
nipi-3Protein NIPI-30.014
C24A1.3Protein C24A1.30.014
acs-19Protein ACS-190.014
btbd-10Protein BTBD-100.014
tct-1Protein TCT-10.014
glit-1Protein GLIT-10.014
mig-5Protein MIG-50.014
scc-1Protein SCC-10.014
sax-7Protein SAX-70.014
T05F1.2Protein T05F1.20.013
nhr-49Protein NHR-490.013
plc-3Protein PLC-30.013
syd-9Protein SYD-90.013
plc-1Protein PLC-10.013
Y51H1A.3Protein Y51H1A.30.013
T19D12.5Protein T19D12.50.013
soc-2Protein SOC-20.013
ced-3Protein CED-30.013
lag-1Protein LAG-10.013
alh-3Protein ALH-30.013
C30H6.7Protein C30H6.70.013
F21F3.6Protein F21F3.60.013
C23H3.3Protein C23H3.30.013
mcm-3Protein MCM-30.013
aldo-2Protein ALDO-20.013
D1043.1Protein D1043.10.013
let-23Protein LET-230.013
C50F2.5Protein C50F2.50.013
M57.2Protein M57.20.013
ant-1.1Protein ANT-1.10.013
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
mapk1mitogen-activated protein kinase 10.773
bcl2l1bcl2-like 10.712
per2period homolog 2 (Drosophila)0.426
pitx3paired-like homeodomain transcription factor 30.339
junjun proto-oncogene0.305
per3period homolog 3 (Drosophila)0.295
tp53tumor protein p530.287
copebcore promoter element binding protein0.268
igf1rbinsulin-like growth factor 1b receptor0.263
adipor2adiponectin receptor 20.259
cry1acryptochrome 1a0.251
cry2bcryptochrome 2b0.227
pafah1b1aplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a0.186
stmn2bstathmin-like 2b0.181
mapk3mitogen-activated protein kinase 30.176
sgk1serum/glucocorticoid regulated kinase 10.172
ptf1apancreas specific transcription factor, 1a0.167
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.140
ef1aelongation factor 1-alpha0.132
cyp3c1cytochrome P450, family 3, subfamily c, polypeptide 10.129
trim13tripartite motif-containing 130.128
idh1isocitrate dehydrogenase 1 (NADP+), soluble0.125
tardbpTAR DNA binding protein0.124
ddb2damage-specific DNA binding protein 20.114
sod1superoxide dismutase 1, soluble0.111
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.110
odc1ornithine decarboxylase 10.105
tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.103
qkquaking0.102
elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast)0.097
ctsbacathepsin B, a0.096
gadd45bagrowth arrest and DNA-damage-inducible, beta a0.095
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.093
pcsk1proprotein convertase subtilisin/kexin type 10.092
cry3cryptochrome 30.088
pgdphosphogluconate hydrogenase0.087
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.084
bmp4bone morphogenetic protein 40.079
gstp1glutathione S-transferase pi0.077
cdh23cadherin-like 230.075
prdx2peroxiredoxin 20.072
aplp2amyloid beta (A4) precursor-like protein 20.071
prdx3peroxiredoxin 30.069
smad2MAD homolog 2 (Drosophila)0.069
slc5a5solute carrier family 5 (sodium iodide symporter), member 50.068
abcc5ATP-binding cassette, sub-family C (CFTR/MRP), member 50.068
hspd1heat shock 60kD protein 1 (chaperonin)0.066
trpv6transient receptor potential cation channel, subfamily V, member 60.065
sepw1selenoprotein W, 10.064
junbljun B proto-oncogene, like0.062
runx1runt-related transcription factor 10.060
cdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)0.057
bbc3BCL2 binding component 30.056
gclcglutamate-cysteine ligase, catalytic subunit0.056
chatcholine acetyltransferase0.054
adipoqladiponectin, C1Q and collagen domain containing, like0.054
pcsk2proprotein convertase subtilisin/kexin type 20.053
nr1h3nuclear receptor subfamily 1, group H, member 30.053
fosv-fos FBJ murine osteosarcoma viral oncogene homolog0.051
sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.050
bactin1bactin10.050
stac3SH3 and cysteine rich domain 30.049
ndufb8NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 80.047
igfbp1ainsulin-like growth factor binding protein 1a0.046
pdlim1PDZ and LIM domain 1 (elfin)0.045
zbtb4zinc finger and BTB domain containing 40.044
evx1even-skipped homeobox 10.044
myhc4myosin heavy chain 40.044
pikfyvephosphoinositide kinase, FYVE finger containing0.044
prox1prospero-related homeobox gene 10.044
zgc:101071zgc:1010710.043
cdh1cadherin 1, epithelial0.043
grb10agrowth factor receptor-bound protein 10a0.042
zgc:64133zgc:641330.042
gpx4bglutathione peroxidase 4b0.041
tnni1altroponin I, skeletal, slow like0.041
col4a5collagen, type IV, alpha 5 (Alport syndrome)0.041
fam60alfamily with sequence similarity 60, member A, like0.040
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.039
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.038
rpsaribosomal protein SA0.038
appaamyloid beta (A4) precursor protein a0.037
hsd3b7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase0.037
rpzrapunzel0.037
col12a1collagen, type XII, alpha 10.037
tpmaalpha-tropomyosin0.037
ikzf1IKAROS family zinc finger 1 (Ikaros)0.036
mdm2transformed 3T3 cell double minute 2 homolog (mouse)0.035
btg1B-cell translocation gene 10.035
arl6ADP-ribosylation factor-like 60.034
hbaa1hemoglobin alpha adult-10.033
dvl3dishevelled, dsh homolog 3 (Drosophila)0.033
tbx20T-box 200.032
mapk7mitogen-activated protein kinase 70.031
smc1alstructural maintenance of chromosomes 1A, like0.031
gapdhsglyceraldehyde-3-phosphate dehydrogenase, spermatogenic0.030
cyp1acytochrome P450, family 1, subfamily A0.030
trpm7transient receptor potential cation channel, subfamily M, member 70.030
tkttransketolase0.030
mstnbmyostatin b0.029
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
JUNjun proto-oncogene0.997
TP53tumor protein p530.997
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.994
DUSP1dual specificity phosphatase 10.988
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.984
EGFRepidermal growth factor receptor0.979
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.973
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.934
BCL2B-cell CLL/lymphoma 20.928
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.891
BCL2L1BCL2-like 10.872
PMLpromyelocytic leukemia0.855
CREBBPCREB binding protein0.831
EPAS1endothelial PAS domain protein 10.823
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.819
FYNFYN oncogene related to SRC, FGR, YES0.780
SOCS3suppressor of cytokine signaling 30.775
MAPK14mitogen-activated protein kinase 140.761
HSPB1heat shock 27kDa protein 10.735
PRDX1peroxiredoxin 10.735
ATF4activating transcription factor 4 (tax-responsive enhancer element B67)0.719
IL1R1interleukin 1 receptor, type I0.715
CRYABcrystallin, alpha B0.684
FHL1four and a half LIM domains 10.666
INSRinsulin receptor0.652
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.649
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.645
MAPK8mitogen-activated protein kinase 80.643
UBCubiquitin C0.642
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.637
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.634
SMAD3SMAD family member 30.631
NDUFA2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa0.618
FHL2four and a half LIM domains 20.602
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.601
RING1ring finger protein 10.583
SOD1superoxide dismutase 1, soluble0.581
ESR1estrogen receptor 10.557
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.547
TTRtransthyretin0.535
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.534
IL1Binterleukin 1, beta0.524
GCLMglutamate-cysteine ligase, modifier subunit0.523
ATF2activating transcription factor 20.521
PLAURplasminogen activator, urokinase receptor0.518
CAV1caveolin 1, caveolae protein, 22kDa0.501
HDAC6histone deacetylase 60.497
GAB1GRB2-associated binding protein 10.488
ZNF746zinc finger protein 7460.480
LATlinker for activation of T cells0.474
ARRB1arrestin, beta 10.455
BBS10Bardet-Biedl syndrome 100.450
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.438
AKT1v-akt murine thymoma viral oncogene homolog 10.432
GRB2growth factor receptor-bound protein 20.427
ARRB2arrestin, beta 20.421
PDCD6IPprogrammed cell death 6 interacting protein0.415
PTK2PTK2 protein tyrosine kinase 20.410
MYD88myeloid differentiation primary response gene (88)0.410
TIMP2TIMP metallopeptidase inhibitor 20.408
BIDBH3 interacting domain death agonist0.405
MAP3K7mitogen-activated protein kinase kinase kinase 70.395
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.390
STRN4striatin, calmodulin binding protein 40.385
NCOR2nuclear receptor corepressor 20.377
ABI2abl-interactor 20.376
NDUFV2NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa0.372
LTBP2latent transforming growth factor beta binding protein 20.369
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.368
CCR5chemokine (C-C motif) receptor 50.366
TKTtransketolase0.362
RHOAras homolog gene family, member A0.362
PRDX2peroxiredoxin 20.358
HDAC2histone deacetylase 20.354
XRCC1X-ray repair complementing defective repair in Chinese hamster cells 10.350
APPamyloid beta (A4) precursor protein0.344
TRIB3tribbles homolog 3 (Drosophila)0.342
NFE2L2nuclear factor (erythroid-derived 2)-like 20.339
DAXXdeath-domain associated protein0.338
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.338
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.337
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.333
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.329
SP1Sp1 transcription factor0.329
FOSFBJ murine osteosarcoma viral oncogene homolog0.325
MPDZmultiple PDZ domain protein0.323
H2AFXH2A histone family, member X0.316
JUNBjun B proto-oncogene0.314
IDEinsulin-degrading enzyme0.304
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.293
MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)0.293
UBQLN4ubiquilin 40.285
NR4A1nuclear receptor subfamily 4, group A, member 10.282
MAP3K8mitogen-activated protein kinase kinase kinase 80.281
TSC22D3TSC22 domain family, member 30.274
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.272
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.263
HBG2hemoglobin, gamma G0.263
TXNthioredoxin0.259
CFL1cofilin 1 (non-muscle)0.256
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.995
Ptenphosphatase and tensin homolog0.992
Mapk14mitogen-activated protein kinase 140.957
Shc1src homology 2 domain-containing transforming protein C10.947
Hbb-b1hemoglobin, beta adult major chain0.942
Rnf2ring finger protein 20.921
Kitkit oncogene0.891
Fbn1fibrillin 10.886
RybpRING1 and YY1 binding protein0.864
Tgfbr1transforming growth factor, beta receptor I0.847
Ptgs2prostaglandin-endoperoxide synthase 20.846
Ctnnb1catenin (cadherin associated protein), beta 10.821
Map3k7mitogen-activated protein kinase kinase kinase 70.799
Prkceprotein kinase C, epsilon0.789
Ltbp2latent transforming growth factor beta binding protein 20.783
Ighimmunoglobulin heavy chain complex0.776
Grb2growth factor receptor bound protein 20.765
Tgfbr2transforming growth factor, beta receptor II0.748
Dusp1dual specificity phosphatase 10.745
JunJun oncogene0.744
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.722
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.706
FosFBJ osteosarcoma oncogene0.692
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.686
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.682
Tlr4toll-like receptor 40.676
Thbs1thrombospondin 10.668
Insrinsulin receptor0.665
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.660
Mapk8mitogen-activated protein kinase 80.656
Clockcircadian locomotor output cycles kaput0.650
SkilSKI-like0.649
Atf2activating transcription factor 20.643
C1qacomplement component 1, q subcomponent, alpha polypeptide0.641
Loxlysyl oxidase0.638
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.631
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.623
Msh2mutS homolog 2 (E. coli)0.586
Klf4Kruppel-like factor 4 (gut)0.581
Gclmglutamate-cysteine ligase, modifier subunit0.578
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.569
Atp5bATP synthase, H+ transporting mitochondrial F1 complex, beta subunit0.556
Prnpprion protein0.549
BaxBCL2-associated X protein0.537
Mapkapk2MAP kinase-activated protein kinase 20.524
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.520
Slc40a1solute carrier family 40 (iron-regulated transporter), member 10.519
Nf1neurofibromatosis 10.519
Slc4a1solute carrier family 4 (anion exchanger), member 10.515
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.505
Ep300E1A binding protein p3000.497
Mapk1mitogen-activated protein kinase 10.496
SrcRous sarcoma oncogene0.479
Ccl2chemokine (C-C motif) ligand 20.470
Rhobras homolog gene family, member B0.467
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.465
C1qccomplement component 1, q subcomponent, C chain0.464
Nos1nitric oxide synthase 1, neuronal0.460
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.440
Mcl1myeloid cell leukemia sequence 10.436
Col1a2collagen, type I, alpha 20.430
Tenc1tensin like C1 domain-containing phosphatase0.428
Ikbkginhibitor of kappaB kinase gamma0.415
Apoeapolipoprotein E0.414
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.407
E2f1E2F transcription factor 10.398
Btg2B-cell translocation gene 2, anti-proliferative0.395
Stat3signal transducer and activator of transcription 30.392
Gclcglutamate-cysteine ligase, catalytic subunit0.389
Fbxl5F-box and leucine-rich repeat protein 50.380
Mknk2MAP kinase-interacting serine/threonine kinase 20.377
Latlinker for activation of T cells0.366
Nr3c1nuclear receptor subfamily 3, group C, member 10.363
C1qbcomplement component 1, q subcomponent, beta polypeptide0.358
Metmet proto-oncogene0.358
Vcpvalosin containing protein0.342
Cyldcylindromatosis (turban tumor syndrome)0.341
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.335
Fgfr1fibroblast growth factor receptor 10.332
Eef1a1eukaryotic translation elongation factor 1 alpha 10.323
Bicc1bicaudal C homolog 1 (Drosophila)0.319
Sgpl1sphingosine phosphate lyase 10.318
C3ar1complement component 3a receptor 10.309
Duox2dual oxidase 20.309
Ppiapeptidylprolyl isomerase A0.304
Mmp2matrix metallopeptidase 20.297
Rac1RAS-related C3 botulinum substrate 10.296
TiparpTCDD-inducible poly(ADP-ribose) polymerase0.293
Ptk2PTK2 protein tyrosine kinase 20.291
Zfp36l1zinc finger protein 36, C3H type-like 10.291
Thbs2thrombospondin 20.284
Col3a1collagen, type III, alpha 10.282
Ahraryl-hydrocarbon receptor0.281
Pkd1polycystic kidney disease 1 homolog0.279
Dsg4desmoglein 40.276
Kpna1karyopherin (importin) alpha 10.276
Suz12suppressor of zeste 12 homolog (Drosophila)0.273
Htra3HtrA serine peptidase 30.270
Cav1caveolin 1, caveolae protein0.269
Psen1presenilin 10.263
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Errfi1ERBB receptor feedback inhibitor 10.849
Col3a1collagen, type III, alpha 10.740
COX2COXII0.661
Nr4a3nuclear receptor subfamily 4, group A, member 30.634
Il6interleukin 60.611
Hbbhemoglobin, beta0.570
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.547
Flt1FMS-related tyrosine kinase 10.541
Junbjun B proto-oncogene0.517
Hoxa2homeo box A20.509
Gadd45agrowth arrest and DNA-damage-inducible, alpha0.495
Gpx4glutathione peroxidase 40.485
Ftlferritin, light polypeptide0.484
Vimvimentin0.470
CYTBcytochrome b0.469
Pebp1phosphatidylethanolamine binding protein 10.459
LOC100134871beta globin minor gene0.450
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.431
Bgnbiglycan0.415
Gzmbgranzyme B0.404
Ccl3chemokine (C-C motif) ligand 30.400
Prlhrprolactin releasing hormone receptor0.384
Mgst2microsomal glutathione S-transferase 20.380
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.375
Col1a1collagen, type I, alpha 10.360
Pgam1phosphoglycerate mutase 1 (brain)0.356
Abcb11ATP-binding cassette, subfamily B (MDR/TAP), member 110.342
Il13ra1interleukin 13 receptor, alpha 10.338
ND2NADH dehydrogenase subunit 20.334
Cryabcrystallin, alpha B0.333
Alas2aminolevulinate, delta-, synthase 20.330
Hes2hairy and enhancer of split 2 (Drosophila)0.329
Htr5b5-hydroxytryptamine (serotonin) receptor 5B0.320
Il18interleukin 180.320
Shc3SHC (Src homology 2 domain containing) transforming protein 30.318
Jak1Janus kinase 10.314
LOC689064beta-globin0.314
Cd46CD46 molecule, complement regulatory protein0.313
Cyp2b2cytochrome P450, family 2, subfamily b, polypeptide 20.311
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.304
Scamp2secretory carrier membrane protein 20.295
Prdx1peroxiredoxin 10.294
Sellselectin L0.290
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.289
Gja1gap junction protein, alpha 10.288
Il1rapinterleukin 1 receptor accessory protein0.284
Elf1E74-like factor 10.282
Pgk1phosphoglycerate kinase 10.275
Gpr182G protein-coupled receptor 1820.273
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.272
Il2rbinterleukin 2 receptor, beta0.265
Casp3caspase 30.260
Dusp1dual specificity phosphatase 10.260
Tnftumor necrosis factor (TNF superfamily, member 2)0.256
Zyxzyxin0.255
Mosc2MOCO sulphurase C-terminal domain containing 20.252
RGD1564664similar to LOC387763 protein0.251
Tpm3tropomyosin 3, gamma0.249
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.242
Nme2non-metastatic cells 2, protein (NM23B) expressed in0.241
Apoa2apolipoprotein A-II0.240
Chrm1cholinergic receptor, muscarinic 10.238
St13suppression of tumorigenicity 130.238
Clic4chloride intracellular channel 40.236
Plauplasminogen activator, urokinase0.234
Klk8kallikrein related-peptidase 80.232
Gstp1glutathione S-transferase pi 10.230
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.230
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.217
Col1a2collagen, type I, alpha 20.217
Cyp2d3cytochrome P450, family 2, subfamily d, polypeptide 30.217
Pla2g4aphospholipase A2, group IVA (cytosolic, calcium-dependent)0.216
Homer3homer homolog 3 (Drosophila)0.215
JunJun oncogene0.215
Il1ainterleukin 1 alpha0.215
Ccnl1cyclin L10.215
Gclmglutamate cysteine ligase, modifier subunit0.215
Cyp4b1cytochrome P450, family 4, subfamily b, polypeptide 10.212
Slc6a4solute carrier family 6 (neurotransmitter transporter, serotonin), member 40.211
Smad1SMAD family member 10.210
Col5a2collagen, type V, alpha 20.208
Pkm2pyruvate kinase, muscle0.207
Lamp2lysosomal-associated membrane protein 20.206
Rararetinoic acid receptor, alpha0.204
Foxd3forkhead box D30.202
Ptgs2prostaglandin-endoperoxide synthase 20.201
Egfrepidermal growth factor receptor0.198
Epas1endothelial PAS domain protein 10.198
Crygdcrystallin, gamma D0.197
Egr2early growth response 20.197
Socs3suppressor of cytokine signaling 30.196
Clec4fC-type lectin domain family 4, member f0.196
Hspe1heat shock protein 1 (chaperonin 10)0.195
Nr4a1nuclear receptor subfamily 4, group A, member 10.195
Klf4Kruppel-like factor 4 (gut)0.192
Ces2ccarboxylesterase 2C0.191
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.190
Txnrd1thioredoxin reductase 10.190
Fabp5fatty acid binding protein 5, epidermal0.189
Grm7glutamate receptor, metabotropic 70.186
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
PRX1Prx1p0.814
PHO85Pho85p0.742
TRX2Trx2p0.595
SOD1Sod1p0.571
TRR1Trr1p0.509
AFT1Aft1p0.500
CTT1Ctt1p0.471
YAP1Yap1p0.440
AHP1Ahp1p0.415
SNF1Snf1p0.387
AIM17Aim17p0.384
TSA1Tsa1p0.346
HOG1Hog1p0.328
SLT2Slt2p0.307
CUP1-1Cup1-1p0.289
RFS1Rfs1p0.286
ACS2Acs2p0.264
ZWF1Zwf1p0.255
CUP1-2Cup1-2p0.243
KSS1Kss1p0.229
CRM1Crm1p0.221
HMX1Hmx1p0.220
SSL2Ssl2p0.220
GLR1Glr1p0.216
YCF1Ycf1p0.209
MOB1Mob1p0.202
GLN3Gln3p0.197
DDR48Ddr48p0.187
APN2Apn2p0.183
ALD4Ald4p0.181
POG1Pog1p0.179
GRX2Grx2p0.176
HOP1Hop1p0.174
GCY1Gcy1p0.171
YSA1Ysa1p0.170
RHO1Rho1p0.169
NDE1Nde1p0.168
TSA2Tsa2p0.165
SKO1Sko1p0.161
VMA5Vma5p0.161
SIR2Sir2p0.160
IDP2Idp2p0.154
HST3Hst3p0.153
ALD6Ald6p0.153
TSL1Tsl1p0.153
CRZ1Crz1p0.148
NTH2Nth2p0.145
RAD16Rad16p0.144
GRE2Gre2p0.143
GRE3Gre3p0.143
HYR1Hyr1p0.141
DBF20Dbf20p0.141
YOL087Chypothetical protein0.140
CNB1Cnb1p0.139
YNL134Chypothetical protein0.138
STR3Str3p0.138
TRX3Trx3p0.137
RAD51Rad51p0.136
STE11Ste11p0.135
HSF1Hsf1p0.135
MIG2Mig2p0.135
GFA1Gfa1p0.133
HRP1Hrp1p0.133
XBP1Xbp1p0.133
STI1Sti1p0.131
FAR11Far11p0.130
SAC7Sac7p0.129
CAT2Cat2p0.128
GAT2Gat2p0.127
CYC8Cyc8p0.126
FPK1Fpk1p0.125
RBK1Rbk1p0.125
SCH9Sch9p0.119
CBK1Cbk1p0.119
ARE1Are1p0.119
RSC6Rsc6p0.118
SOD2Sod2p0.118
VAC7Vac7p0.117
ROM2Rom2p0.116
RED1Red1p0.116
TPS1Tps1p0.116
ITC1Itc1p0.113
KAP122Kap122p0.112
ECM38Ecm38p0.112
YAK1Yak1p0.111
CCS1Ccs1p0.107
MIG3Mig3p0.107
PPH3Pph3p0.107
PET10Pet10p0.106
GPA2Gpa2p0.105
YPL150Whypothetical protein0.104
HYP2Hyp2p0.104
GSH1Gsh1p0.104
OM45Om45p0.103
PPG1Ppg1p0.103
SLM1Slm1p0.102
RPN4Rpn4p0.102
RGS2Rgs2p0.101
MSN2Msn2p0.101
GSP2Gsp2p0.100