The network for 'regulation of immune system process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

NameDescriptionProbabilityFunc Analog Organism
InRInsulin-like receptor0.963
Pi3K92ECG4141 gene product from transcript CG4141-RB0.933
Spn27ASerpin 27A0.905
aopanterior open0.898
mbcmyoblast city0.895
Atg1Autophagy-specific gene 10.882
dcodiscs overgrown0.879
EgfrEpidermal growth factor receptor0.876
DptBDiptericin B0.764
Mpk2CG5475 gene product from transcript CG5475-RB0.725
Ras85DRas oncogene at 85D0.699
bratbrain tumor0.698
PGRP-SAPeptidoglycan recognition protein SA0.689
PGRP-LCPeptidoglycan recognition protein LC0.684
Akt1CG4006 gene product from transcript CG4006-RA0.678
CG11347CG11347 gene product from transcript CG11347-RE0.666
grassGram-positive Specific Serine protease0.657
emcextra macrochaetae0.635
PvrPDGF- and VEGF-receptor related0.613
cicubitus interruptus0.591
LamCLamin C0.567
phlpole hole0.556
stcksteamer duck0.551
Rho1CG8416 gene product from transcript CG8416-RB0.536
Tak1TGF-beta activated kinase 10.524
SPESpatzle-Processing Enzyme0.512
TimpTissue inhibitor of metalloproteases0.504
foxoforkhead box, sub-group O0.500
p38bCG7393 gene product from transcript CG7393-RA0.484
Ced-12CG5336 gene product from transcript CG5336-RA0.481
HsfHeat shock factor0.460
cortoCG2530 gene product from transcript CG2530-RA0.459
ird1immune response deficient 10.457
trolterribly reduced optic lobes0.438
Myd88CG2078 gene product from transcript CG2078-RA0.429
ik2IkappaB kinase-like 20.420
rapretina aberrant in pattern0.414
Cp190Centrosomal protein 190kD0.409
ThorCG8846 gene product from transcript CG8846-RA0.405
PGRP-SDCG7496 gene product from transcript CG7496-RA0.397
S6kRPS6-p70-protein kinase0.389
drkdownstream of receptor kinase0.387
MadMothers against dpp0.381
Spn1Serine protease inhibitor 10.379
Mmp1Matrix metalloproteinase 10.372
Tab2TAK1-associated binding protein 20.332
numbCG3779 gene product from transcript CG3779-RB0.322
psidinphagocyte signaling impaired0.321
zfh1Zn finger homeodomain 10.321
LysDLysozyme D0.319
Uba1Ubiquitin activating enzyme 10.315
JIL-1CG6297 gene product from transcript CG6297-RA0.310
Hr39Hormone receptor-like in 390.308
CaMKIICalcium/calmodulin-dependent protein kinase II0.303
fogfolded gastrulation0.300
Atg7Autophagy-specific gene 70.299
HLHmgammaE(spl) region transcript mgamma0.299
Zfrp8Zinc finger protein RP-80.297
CG9014CG9014 gene product from transcript CG9014-RA0.296
chicoCG5686 gene product from transcript CG5686-RB0.294
E(spl)Enhancer of split0.293
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.991
tal1T-cell acute lymphocytic leukemia 10.971
mpxmyeloid-specific peroxidase0.932
bmp2bbone morphogenetic protein 2b0.756
cdx4caudal type homeo box transcription factor 40.684
tp63tumor protein p630.535
mmp9matrix metalloproteinase 90.530
osr1odd-skipped related 1 (Drosophila)0.472
socs1suppressor of cytokine signaling 10.445
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.443
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.433
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.418
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.371
csf1racolony stimulating factor 1 receptor, a0.352
cdh1cadherin 1, epithelial0.348
c3bcomplement component c3b0.348
fn1fibronectin 10.345
fgf3fibroblast growth factor 30.341
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.339
mycamyelocytomatosis oncogene a0.339
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.321
sh3gl1bSH3-domain GRB2-like 1b0.303
tgfb3transforming growth factor, beta 30.278
cyp26b1cytochrome P450, family 26, subfamily b, polypeptide 10.278
dnmt4DNA (cytosine-5-)-methyltransferase 40.273
shhasonic hedgehog a0.266
mmp13amatrix metalloproteinase 13a0.263
ip6k2inositol hexaphosphate kinase 20.257
etv2ets variant gene 20.253
arl4abADP-ribosylation factor-like 4ab0.249
fli1bfriend leukemia integration 1b0.248
junbjun B proto-oncogene0.244
lfnglunatic fringe homolog0.240
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.236
ergv-ets erythroblastosis virus E26 oncogene like (avian)0.235
mapk3mitogen-activated protein kinase 30.217
adora2aaadenosine A2a receptor a0.209
fgf17fibroblast growth factor 170.206
sox7SRY-box containing gene 70.202
tgfb1atransforming growth factor, beta 1a0.197
notum3notum 30.197
fstafollistatin a0.180
polmpolymerase (DNA directed), mu0.178
ifnphi1interferon phi 10.174
furinbfurin (paired basic amino acid cleaving enzyme) b0.171
otpaorthopedia homolog a0.169
tlr21toll-like receptor 210.165
msnamoesin a0.164
runx2arunt-related transcription factor 2a0.161
fstl1bfollistatin-like 1b0.160
mtpmicrosomal triglyceride transfer protein0.156
lta4hleukotriene A4 hydrolase0.155
her1hairy-related 10.151
spns2spinster homolog 2 (Drosophila)0.151
notch3notch homolog 30.147
tlr2toll-like receptor 20.146
timp2btissue inhibitor of metalloproteinase 2b0.144
axin2axin 2 (conductin, axil)0.144
fn1bfibronectin 1b0.143
stab2stabilin 20.142
ighmimmunoglobulin heavy constant mu and immunoglobulin heavy constant mu0.140
ptprcprotein tyrosine phosphatase, receptor type, C0.140
edn1endothelin 10.138
tie1endothelium-specific receptor tyrosine kinase 10.136
tnfatumor necrosis factor a (TNF superfamily, member 2)0.129
lhx1aLIM homeobox 1a0.127
rhbgRhesus blood group, B glycoprotein0.127
npy4rneuropeptide Y receptor Y40.126
tnfsf18tumor necrosis factor (ligand) superfamily, member 180.125
gata6GATA-binding protein 60.124
nr2f5nuclear receptor subfamily 2, group F, member 50.121
meis1myeloid ecotropic viral integration 10.120
gdnfglial cell derived neurotrophic factor0.120
grnagranulin a0.119
hoxc8ahomeo box C8a0.118
apoebapolipoprotein Eb0.116
socs3asuppressor of cytokine signaling 3a0.116
slc30a7solute carrier family 30 (zinc transporter), member 70.114
ptpn6protein tyrosine phosphatase, non-receptor type 60.112
fabp6fatty acid binding protein 6, ileal (gastrotropin)0.111
rag1recombination activating gene 10.110
fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.105
epas1bendothelial PAS domain protein 1b0.102
smoc2secreted modular calcium binding protein 20.101
nipblbnovel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)0.101
f2rcoagulation factor II (thrombin) receptor0.099
tlr9toll-like receptor 90.099
tlr3toll-like receptor 30.097
fcho2FCH domain only 20.096
pkd2polycystic kidney disease 20.095
rhogbras homolog gene family, member Gb0.094
shbgsex hormone binding globulin0.093
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.093
hoxd4ahomeo box D4a0.093
ikzf1IKAROS family zinc finger 1 (Ikaros)0.090
piwil1piwi-like 1 (Drosophila)0.090
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Sellselectin L0.867
Cd4Cd4 molecule0.822
Hckhemopoietic cell kinase0.753
Cd53Cd53 molecule0.752
Klrd1killer cell lectin-like receptor, subfamily D, member 10.597
Ccr5chemokine (C-C motif) receptor 50.596
Mmp12matrix metallopeptidase 120.578
Cxcl10chemokine (C-X-C motif) ligand 100.574
Csf1colony stimulating factor 1 (macrophage)0.560
Cd86CD86 molecule0.485
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.484
Il1binterleukin 1 beta0.471
Gzmkgranzyme K0.467
Socs3suppressor of cytokine signaling 30.466
Cd5Cd5 molecule0.462
Ccl4chemokine (C-C motif) ligand 40.454
Cd37CD37 molecule0.449
Fcgr2aFc fragment of IgG, low affinity IIa, receptor (CD32)0.448
RT1-BaRT1 class II, locus Ba0.440
Atf3activating transcription factor 30.434
Calcrlcalcitonin receptor-like0.426
RT1-DaRT1 class II, locus Da0.417
Aif1allograft inflammatory factor 10.416
Sirpasignal-regulatory protein alpha0.415
Icam1intercellular adhesion molecule 10.411
P2ry14purinergic receptor P2Y, G-protein coupled, 140.408
Ctsscathepsin S0.396
Cd38CD38 molecule0.392
Cd14CD14 molecule0.382
Flt1FMS-related tyrosine kinase 10.379
Ly86lymphocyte antigen 860.376
C3complement component 30.361
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.347
Il6interleukin 60.347
Casp1caspase 10.344
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.326
Kcnh7potassium voltage-gated channel, subfamily H (eag-related), member 70.319
RT1-CE12RT1 class I, locus CE120.318
Npr1natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)0.318
Cd68Cd68 molecule0.313
Ccl2chemokine (C-C motif) ligand 20.313
Mrgprx3MAS-related GPR, member X30.310
Vav1vav 1 guanine nucleotide exchange factor0.303
Ctsjcathepsin J0.299
Dnase1l3deoxyribonuclease 1-like 30.296
Ccl3chemokine (C-C motif) ligand 30.291
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.289
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.281
Iappislet amyloid polypeptide0.281
Cxcr4chemokine (C-X-C motif) receptor 40.278
Vom2r27vomeronasal 2 receptor, 270.277
Neurl3neuralized homolog 3 (Drosophila)0.276
Cfbcomplement factor B0.275
Cficomplement factor I0.271
Olr1078olfactory receptor 10780.269
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.268
Prf1perforin 1 (pore forming protein)0.268
Jak1Janus kinase 10.267
Ptprcprotein tyrosine phosphatase, receptor type, C0.264
Tnftumor necrosis factor (TNF superfamily, member 2)0.264
RT1-BbRT1 class II, locus Bb0.263
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.259
Arl11ADP-ribosylation factor-like 110.254
Vcam1vascular cell adhesion molecule 10.249
Prrx1paired related homeobox 10.248
Cd247Cd247 molecule0.246
Slc6a12solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 120.242
LOC100360403ATP-binding cassette, sub-family C, member 9-like0.242
Pla2g2aphospholipase A2, group IIA (platelets, synovial fluid)0.240
Rac2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.240
Nos2nitric oxide synthase 2, inducible0.238
Fgd2FYVE, RhoGEF and PH domain containing 20.234
Ccl22chemokine (C-C motif) ligand 220.232
Grm5glutamate receptor, metabotropic 50.232
Plauplasminogen activator, urokinase0.221
Folr2folate receptor 2 (fetal)0.220
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.218
Tmem37transmembrane protein 370.213
Gpnmbglycoprotein (transmembrane) nmb0.213
Fcnbficolin B0.212
Nek9NIMA (never in mitosis gene a)- related kinase 90.207
Casp8caspase 80.206
Ripk3receptor-interacting serine-threonine kinase 30.201
Dusp4dual specificity phosphatase 40.200
Adcy10adenylate cyclase 10 (soluble)0.199
Cybbcytochrome b-245, beta polypeptide0.199
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.199
Tlr7toll-like receptor 70.196
Gdf10growth differentiation factor 100.195
Reg3bregenerating islet-derived 3 beta0.193
Cfpcomplement factor properdin0.193
Mrc1mannose receptor, C type 10.192
Ncf4neutrophil cytosolic factor 40.189
C2complement component 20.189
Cd40lgCD40 ligand0.189
Slco2b1solute carrier organic anion transporter family, member 2b10.187
Adora2aadenosine A2a receptor0.185
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism