The network for 'spermine metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

spermine metabolic process

The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
INO80CINO80 complex subunit C0.187
SAT1spermidine/spermine N1-acetyltransferase 10.042
BZW1basic leucine zipper and W2 domains 10.031
TMEM66transmembrane protein 660.022
FUNDC2FUN14 domain containing 20.017
LNX1ligand of numb-protein X 10.012
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Phtf2putative homeodomain transcription factor 20.078
Syncripsynaptotagmin binding, cytoplasmic RNA interacting protein0.040
Serbp1serpine1 mRNA binding protein 10.034
Otud6bOTU domain containing 6B0.024
Zc3h15zinc finger CCCH-type containing 150.023
Eif4eeukaryotic translation initiation factor 4E0.021
Cse1lchromosome segregation 1-like (S. cerevisiae)0.019
Kpna1karyopherin (importin) alpha 10.018
Prps1phosphoribosyl pyrophosphate synthetase 10.017
Xpo1exportin 1, CRM1 homolog (yeast)0.014
Kpna3karyopherin (importin) alpha 30.013
Rwdd4aRWD domain containing 4A0.013
Ppp4r2protein phosphatase 4, regulatory subunit 20.011
Hsph1heat shock 105kDa/110kDa protein 10.011
Chordc1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 10.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.039
Zh16ZH16 protein0.019
Suclg2succinate-CoA ligase, GDP-forming, beta subunit0.014
Ndrg2N-myc downstream regulated gene 20.013
Pdpk13-phosphoinositide dependent protein kinase-10.011
Usp10ubiquitin specific peptidase 100.010
Clcn3chloride channel 30.010
Slc38a2solute carrier family 38, member 20.010
Abhd14babhydrolase domain containing 14b0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism