The network for 'regulation of ph' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of ph

Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.

NameDescriptionProbabilityFunc Analog Organism
Vha68-2CG3762 gene product from transcript CG3762-RA0.993
VhaAC39Vacuolar H[+]-ATPase C39 subunit0.963
Rab2Rab-protein 20.940
Vha26Vacuolar H[+]-ATPase 26kD E subunit0.805
VhaSFDVacuolar H[+]-ATPase SFD subunit0.709
Rbcn-3ARabconnectin-3A0.593
Rab7Rab-protein 70.584
Rab6Rab-protein 60.431
Vha100-2CG18617 gene product from transcript CG18617-RB0.248
Vha55Vacuolar H[+]-ATPase 55kD B subunit0.244
CG12004CG12004 gene product from transcript CG12004-RC0.180
Rbcn-3BRabconnectin-3B0.136
galectinCG11372 gene product from transcript CG11372-RA0.127
14-3-3zetaCG17870 gene product from transcript CG17870-RB0.112
Rab14Rab-protein 140.073
Gs2Glutamine synthetase 20.048
CG3961CG3961 gene product from transcript CG3961-RC0.042
UBL3CG9038 gene product from transcript CG9038-RC0.042
CG9003CG9003 gene product from transcript CG9003-RD0.041
kstkarst0.036
CG8029CG8029 gene product from transcript CG8029-RB0.034
CG9990CG9990 gene product from transcript CG9990-RA0.023
endoAendophilin A0.022
karkarmoisin0.021
LmptLimpet0.019
skapskpA associated protein0.016
CG4306CG4306 gene product from transcript CG4306-RA0.016
OatOrnithine aminotransferase precursor0.016
PisPhosphatidylinositol synthase0.016
CG15771CG15771 gene product from transcript CG15771-RA0.016
rogdiCG7725 gene product from transcript CG7725-RB0.014
CG3061CG3061 gene product from transcript CG3061-RA0.014
CanB2Calcineurin B20.014
Mct1Monocarboxylate transporter 10.014
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.013
Lsd-1Lipid storage droplet-10.013
Spn1Serine protease inhibitor 10.013
VhaPPA1-1CG7007 gene product from transcript CG7007-RA0.013
Vha16Vacuolar H[+] ATPase 16kD subunit0.012
CG31076CG31076 gene product from transcript CG31076-RA0.012
CG42863CG42863 gene product from transcript CG42863-RB0.011
CG3164CG3164 gene product from transcript CG3164-RA0.011
VhaM9.7-2CG7625 gene product from transcript CG7625-RA0.011
deltaCOPdelta-coatomer protein0.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
vha-15Protein VHA-150.399
CELE_B0513.5Protein B0513.50.154
pept-1Protein PEPT-10.134
nep-17Protein NEP-170.094
vha-19Protein VHA-190.088
unc-108Protein UNC-1080.087
T25C12.3Protein T25C12.30.085
F14B8.2Protein F14B8.20.076
nkb-3Protein NKB-30.074
hpo-32Protein HPO-320.043
T27A3.1Protein T27A3.10.032
Y39D8A.1Protein Y39D8A.10.032
vha-16Protein VHA-160.031
erm-1Protein ERM-10.030
vha-5Protein VHA-50.028
K10C2.1Protein K10C2.10.027
F33H2.3Protein F33H2.30.026
C48B4.1Protein C48B4.10.025
Y71H10A.1Protein Y71H10A.10.024
mpz-2Protein MPZ-20.024
W03F8.4Protein W03F8.40.024
cts-1Protein CTS-10.023
skr-1Protein SKR-10.023
elo-1Protein ELO-10.021
pmp-1Protein PMP-10.020
F32A5.3Protein F32A5.30.020
T08B1.1Protein T08B1.10.019
C52E4.5Protein C52E4.50.019
nduf-2.2Protein NDUF-2.20.018
abt-4Protein ABT-40.018
ugt-48Protein UGT-480.017
vha-11Protein VHA-110.017
pcp-2Protein PCP-20.016
immt-1Protein IMMT-10.016
del-6Protein DEL-60.016
CELE_Y57A10A.2Protein Y57A10A.20.016
mboa-3Protein MBOA-30.015
vha-8Protein VHA-80.015
alh-4Protein ALH-40.013
vha-10Protein VHA-100.013
haao-1Protein HAAO-10.013
C13C4.5Protein C13C4.50.013
C14B1.3Protein C14B1.30.013
mlt-7Protein MLT-70.013
cln-3.3Protein CLN-3.30.013
cdc-42Protein CDC-420.012
prx-12Protein PRX-120.012
dsc-4Protein DSC-40.012
CELE_R02D3.1Protein R02D3.10.011
F28B4.3Protein F28B4.30.011
sft-4Protein SFT-40.011
F48F7.6Protein F48F7.60.011
T16G12.1Protein T16G12.10.011
CELE_F31E8.4Protein F31E8.40.011
F52A8.1Protein F52A8.10.011
pbo-4Protein PBO-40.010
Y40C5A.1Protein Y40C5A.10.010
srv-1Protein SRV-10.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ca2carbonic anhydrase II0.976
slc9a3.2solute carrier family 9 (sodium/hydrogen exchanger), member 3.20.679
ca15acarbonic anhydrase XV a0.648
atp6v1hATPase, H+ transporting, lysosomal, V1 subunit H0.647
trpv6transient receptor potential cation channel, subfamily V, member 60.519
slc4a1bsolute carrier family 4, anion exchanger, member 1b0.481
slc26a3solute carrier family 26, member 30.369
slc26a4solute carrier family 26, member 40.326
atp6v1baATPase, H+ transporting, lysosomal, V1 subunit B, member a0.324
cnga5cyclic nucleotide gated channel alpha 50.238
atp6v1dATPase, H+ transporting, V1 subunit D and ATPase, H+ transporting, V1 subunit D0.238
rhcgl1Rhesus blood group, C glycoprotein, like 10.214
rhagRhesus blood group-associated glycoprotein0.213
th2tyrosine hydroxylase 20.192
slc4a4bsolute carrier family 4, sodium bicarbonate cotransporter, member 4b0.168
stc1lstanniocalcin 1, like0.168
rhcgbRhesus blood group, C glycoprotein b0.160
atp1b1bATPase, Na+/K+ transporting, beta 1b polypeptide0.147
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.138
slc12a10.2solute carrier family 12 (sodium/potassium/chloride transporters), member 10.20.133
fabp6fatty acid binding protein 6, ileal (gastrotropin)0.125
LOC100005108novel protein similar to solute carrier family 26, member 5 (slc26a5)0.123
prkceaprotein kinase C, epsilon a0.120
LOC566020Gig2-like protein DreO0.118
atp6v1g1ATPase, H+ transporting, V1 subunit G isoform 10.118
tal1T-cell acute lymphocytic leukemia 10.115
tacc2transforming, acidic coiled-coil containing protein 20.113
atp6v1fATPase, H+ transporting, V1 subunit F0.109
atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.105
mgpmatrix Gla protein0.104
neurog3neurogenin 30.102
atp6ap2ATPase, H+ transporting, lysosomal accessory protein 20.100
LOC790901glucose-dependent insulinotropic polypeptide0.095
mt2metallothionein 20.092
atp6v1e1bATPase, H+ transporting, lysosomal, V1 subunit E isoform 1b0.086
atp1a1a.2ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide0.085
egr2bearly growth response 2b0.085
snf8SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)0.084
gcm2glial cells missing homolog 2 (Drosophila)0.084
orgoogenesis-related gene0.084
sh3gl2SH3-domain GRB2-like 20.083
midnmidnolin0.081
si:ch211-209p5.2si:ch211-209p5.20.079
qkquaking0.078
calcacalcitonin/calcitonin-related polypeptide, alpha0.077
pth1aparathyroid hormone 1a0.075
rtcd1RNA terminal phosphate cyclase domain 10.074
cyp3c1cytochrome P450, family 3, subfamily c, polypeptide 10.074
cldn15aclaudin 15a0.071
vasavasa homolog0.071
acsl4aacyl-CoA synthetase long-chain family member 4a0.069
si:dkey-228g21.4si:dkey-228g21.40.068
dmrt2adoublesex and mab-3 related transcription factor 2a0.067
a2mlalpha-2-macroglobulin-like0.066
pglyrp6peptidoglycan recognition protein 60.066
zgc:123177zgc:1231770.065
ldhalactate dehydrogenase A40.063
kdm5bblysine (K)-specific demethylase 5Bb0.063
fabp11afatty acid binding protein 11a0.063
atp6v0d1ATPase, H+ transporting, V0 subunit D isoform 10.063
sb:cb101sb:cb1010.063
insm1ainsulinoma-associated 1a0.063
ndfip1Nedd4 family interacting protein 10.062
fcer1glFc receptor, IgE, high affinity I, gamma polypeptide like0.062
LOC569232UPF0672 protein CXorf36 homolog0.062
aldocbaldolase C, fructose-bisphosphate, b0.060
bdnfbrain-derived neurotrophic factor0.059
adra2badrenergic, alpha-2B-, receptor0.059
zeb1zinc finger E-box binding homeobox 10.058
sb:cb166sb:cb1660.058
hk1hexokinase 10.057
sdf4stromal cell derived factor 40.056
nt5e5'-nucleotidase, ecto (CD73)0.056
col7a1lcollagen type VII alpha 1-like0.056
aqp7aquaporin 70.056
snx4sorting nexin 40.055
sst3somatostatin 30.055
calm2acalmodulin 2a (phosphorylase kinase, delta)0.054
zgc:158605zgc:1586050.053
pyyapeptide YYa0.051
atp1a3bATPase, Na+/K+ transporting, alpha 3b polypeptide0.050
ints6integrator complex subunit 60.049
zgc:66433zgc:664330.049
lhbluteinizing hormone, beta polypeptide0.049
atp6v1alATPase, H+ transporting, lysosomal V1 subunit A, like0.049
march5lmembrane-associated ring finger (C3HC4) 5, like0.049
mtormechanistic target of rapamycin (serine/threonine kinase)0.048
eno1enolase 1, (alpha)0.048
scn1asodium channel, voltage-gated, type I, alpha0.047
esrraestrogen-related receptor alpha0.046
trim2atripartite motif-containing 2a0.046
pbxip1bpre-B-cell leukemia homeobox interacting protein 1b0.046
ca4acarbonic anhydrase IV a0.046
pkm2apyruvate kinase, muscle, a0.044
ndrg1N-myc downstream regulated gene 10.044
si:ch211-288h2.6si:ch211-288h2.60.044
otpaorthopedia homolog a0.043
chrm2acholinergic receptor, muscarinic 2a0.041
oxtloxytocin-like0.041
LOC796298isotocin receptor-like 10.041
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BCL2B-cell CLL/lymphoma 20.906
ATP6V1AATPase, H+ transporting, lysosomal 70kDa, V1 subunit A0.441
BCL2L1BCL2-like 10.159
BCL2L11BCL2-like 11 (apoptosis facilitator)0.119
ATP6V1E1ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E10.095
RAB5ARAB5A, member RAS oncogene family0.089
ATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b0.089
ATP6V1B2ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B20.086
ATP6V1DATPase, H+ transporting, lysosomal 34kDa, V1 subunit D0.075
GOLGA2golgin A20.066
ATP6V0CATPase, H+ transporting, lysosomal 16kDa, V0 subunit c0.053
BAK1BCL2-antagonist/killer 10.052
ATP6V0D1ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d10.048
ATF2activating transcription factor 20.045
BADBCL2-associated agonist of cell death0.042
GDI2GDP dissociation inhibitor 20.042
OCRLoculocerebrorenal syndrome of Lowe0.037
CANXcalnexin0.028
ATP6V0A1ATPase, H+ transporting, lysosomal V0 subunit a10.026
NAPAN-ethylmaleimide-sensitive factor attachment protein, alpha0.025
CUL1cullin 10.024
AP1G1adaptor-related protein complex 1, gamma 1 subunit0.022
NAGKN-acetylglucosamine kinase0.019
BIDBH3 interacting domain death agonist0.019
DNM2dynamin 20.018
PLD3phospholipase D family, member 30.017
RNF144Bring finger protein 144B0.017
HMG20Ahigh mobility group 20A0.016
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.016
RNR2l-rRNA0.015
PDZK1PDZ domain containing 10.015
SPHARS-phase response (cyclin related)0.014
ATP6V1C1ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C10.014
PLEKHB2pleckstrin homology domain containing, family B (evectins) member 20.014
ATP6AP1ATPase, H+ transporting, lysosomal accessory protein 10.014
PMAIP1phorbol-12-myristate-13-acetate-induced protein 10.013
RAB1ARAB1A, member RAS oncogene family0.013
BTRCbeta-transducin repeat containing0.012
ARF3ADP-ribosylation factor 30.012
CTSAcathepsin A0.012
CHP2calcineurin B homologous protein 20.012
WSB2WD repeat and SOCS box containing 20.012
CLCN3chloride channel 30.011
SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.011
ATP6V1G1ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G10.011
MAPK14mitogen-activated protein kinase 140.010
WBP2WW domain binding protein 20.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Slc4a1solute carrier family 4 (anion exchanger), member 10.805
Cftrcystic fibrosis transmembrane conductance regulator homolog0.799
Slc4a4solute carrier family 4 (anion exchanger), member 40.689
Tyrp1tyrosinase-related protein 10.651
Umoduromodulin0.588
Kitkit oncogene0.575
Slc9a3solute carrier family 9 (sodium/hydrogen exchanger), member 30.552
Hbb-b1hemoglobin, beta adult major chain0.535
Thrbthyroid hormone receptor beta0.500
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.427
Sox10SRY-box containing gene 100.408
Pax8paired box gene 80.363
Spna1spectrin alpha 10.340
Ece1endothelin converting enzyme 10.323
Mitfmicrophthalmia-associated transcription factor0.282
LOC100503041PDZ domain-containing protein 7-like0.262
Hbb-b2hemoglobin, beta adult minor chain0.254
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.206
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.202
Ank1ankyrin 1, erythroid0.168
Agtrapangiotensin II, type I receptor-associated protein0.149
Eya1eyes absent 1 homolog (Drosophila)0.140
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.134
Kitlkit ligand0.121
Ednrbendothelin receptor type B0.117
Hsd3b4hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 40.102
Tmprss6transmembrane serine protease 60.097
Krt86keratin 860.095
Clstn1calsyntenin 10.095
Fgfr1fibroblast growth factor receptor 10.092
Atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.090
Atp6v0a4ATPase, H+ transporting, lysosomal V0 subunit A40.089
Espnespin0.088
Gypaglycophorin A0.087
Hba-a1hemoglobin alpha, adult chain 10.087
Tyrtyrosinase0.085
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 10.078
Ahspalpha hemoglobin stabilizing protein0.077
Trpv4transient receptor potential cation channel, subfamily V, member 40.075
Slc12a6solute carrier family 12, member 60.074
Krt36keratin 360.074
Vamp2vesicle-associated membrane protein 20.062
St14suppression of tumorigenicity 14 (colon carcinoma)0.060
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.057
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.057
Foxi1forkhead box I10.057
Cckbrcholecystokinin B receptor0.057
Hoxa1homeobox A10.057
Klf1Kruppel-like factor 1 (erythroid)0.056
Slc13a1solute carrier family 13 (sodium/sulfate symporters), member 10.056
Slc12a1solute carrier family 12, member 10.056
Oca2oculocutaneous albinism II0.055
Dlx6distal-less homeobox 60.055
Foxi3forkhead box I30.055
Lystlysosomal trafficking regulator0.053
Pcsk4proprotein convertase subtilisin/kexin type 40.050
Gjb6gap junction protein, beta 60.050
Itgb1integrin beta 1 (fibronectin receptor beta)0.050
Edn1endothelin 10.049
Esr1estrogen receptor 1 (alpha)0.048
Ush1gUsher syndrome 1G homolog (human)0.048
Pspnpersephin0.048
NdpNorrie disease (pseudoglioma) (human)0.048
BaxBCL2-associated X protein0.047
Cdh23cadherin 23 (otocadherin)0.047
Ppp1r1bprotein phosphatase 1, regulatory (inhibitor) subunit 1B0.047
Gfapglial fibrillary acidic protein0.047
Vegfavascular endothelial growth factor A0.046
Ceacam16carcinoembryonic antigen-related cell adhesion molecule 160.046
Eporerythropoietin receptor0.046
Slc9a3r1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.046
Slc5a2solute carrier family 5 (sodium/glucose cotransporter), member 20.045
Alas2aminolevulinic acid synthase 2, erythroid0.044
Fa2hfatty acid 2-hydroxylase0.044
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.043
Slc13a2solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 20.043
Hba-a2hemoglobin alpha, adult chain 20.043
Zfp92zinc finger protein 920.041
Nrp1neuropilin 10.039
Kcnj10potassium inwardly-rectifying channel, subfamily J, member 100.039
Oprk1opioid receptor, kappa 10.039
BsndBartter syndrome, infantile, with sensorineural deafness (Barttin)0.038
KelKell blood group0.038
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.038
Hmx3H6 homeobox 30.037
Malmyelin and lymphocyte protein, T-cell differentiation protein0.037
Exoc6exocyst complex component 60.036
Slc26a7solute carrier family 26, member 70.035
Ovol1OVO homolog-like 1 (Drosophila)0.035
Ehfets homologous factor0.034
Kcne1potassium voltage-gated channel, Isk-related subfamily, member 10.034
Prrx1paired related homeobox 10.034
Tspo2translocator protein 20.033
Slc12a2solute carrier family 12, member 20.033
Car2carbonic anhydrase 20.033
Fcgr2bFc receptor, IgG, low affinity IIb0.033
Fxyd4FXYD domain-containing ion transport regulator 40.032
Ace2angiotensin I converting enzyme (peptidyl-dipeptidase A) 20.032
Marveld3MARVEL (membrane-associating) domain containing 30.032
Slc40a1solute carrier family 40 (iron-regulated transporter), member 10.031
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
VMA1Vma1p0.065
VMA13Vma13p0.058
VMA4Vma4p0.030
VPS8Vps8p0.027
NHX1Nhx1p0.024
CNB1Cnb1p0.022
COT1Cot1p0.022
GTR1Gtr1p0.021
TLG2Tlg2p0.020
CCW12Ccw12p0.019
VMA5Vma5p0.018
IML1Iml1p0.018
SYS1Sys1p0.018
INP52Inp52p0.018
VAM6Vam6p0.018
CTF13Ctf13p0.017
IST2Ist2p0.016
VPH1Vph1p0.016
CDC53Cdc53p0.016
KIC1Kic1p0.015
VAC8Vac8p0.015
PEP3Pep3p0.015
PDR12Pdr12p0.014
AVT1Avt1p0.014
ARR3Arr3p0.014
YDR307Whypothetical protein0.014
VMA6Vma6p0.013
NEO1Neo1p0.013
SRD1Srd1p0.013
IRC19Irc19p0.013
PMR1Pmr1p0.013
ARP10Arp10p0.013
ADH2Adh2p0.013
LEU2Leu2p0.013
VPS51Vps51p0.013
ERS1Ers1p0.013
HUR1Hur1p0.012
VAB2Vab2p0.012
YOL038C-Ahypothetical protein0.012
YLR162Whypothetical protein0.012
VPS28Vps28p0.012
YLR264C-Ahypothetical protein0.012
SGE1Sge1p0.012
UPS3Ups3p0.012
BCK2Bck2p0.012
PPQ1Ppq1p0.012
SMF3Smf3p0.012
MER1Mer1p0.012
MOB1Mob1p0.012
CDC37Cdc37p0.012
BST1Bst1p0.011
CUP1-1Cup1-1p0.011
YHR078Whypothetical protein0.011
HXT3Hxt3p0.011
ZPS1Zps1p0.011
GTR2Gtr2p0.011
SIS1Sis1p0.011
MF(ALPHA)2Mf(alpha)2p0.011
YLR042Chypothetical protein0.011
YAR068Whypothetical protein0.011
ATP6Atp6p0.011
YBR013Chypothetical protein0.011
VPS21Vps21p0.011
MPT5Mpt5p0.011
BNA4Bna4p0.011
YPR157Whypothetical protein0.011
SKP2Skp2p0.011
HAL5Hal5p0.011
SPL2Spl2p0.011
YKR075Chypothetical protein0.011
SPF1Spf1p0.011
OPT2Opt2p0.011
AUA1Aua1p0.011
HPF1Hpf1p0.011
PAR32Par32p0.011
PTR2Ptr2p0.011
APM2Apm2p0.011
CPD1Cpd1p0.011
BSC1Bsc1p0.011
YCH1Ych1p0.011
RRI1Rri1p0.011
YAR066Whypothetical protein0.011
VPS29Vps29p0.010
MSO1Mso1p0.010
YIR035Chypothetical protein0.010
GEF1Gef1p0.010
FMT1Fmt1p0.010
YMR122W-Ahypothetical protein0.010
MF(ALPHA)1Mf(alpha)1p0.010
ENT4Ent4p0.010
YOL013W-Ahypothetical protein0.010
YLR040Chypothetical protein0.010
CHA1Cha1p0.010
SCM4Scm4p0.010
URA3Ura3p0.010
SSU1Ssu1p0.010
TSC3Tsc3p0.010
TIP1Tip1p0.010
OYE3Oye3p0.010