The network for 'mitochondrial fusion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mitochondrial fusion

Merging of two or more mitochondria within a cell to form a single compartment.

NameDescriptionProbabilityFunc Analog Organism
Pink1PTEN-induced putative kinase 10.998
parkparkin0.820
MarfMitochondrial assembly regulatory factor0.798
rho-7rhomboid-70.327
porinCG6647 gene product from transcript CG6647-RA0.321
opa1-likeoptic atrophy 1-like0.256
Sod2Superoxide dismutase 2 (Mn)0.219
TazTafazzin0.179
Letm1CG4589 gene product from transcript CG4589-RB0.160
molmoladietz0.106
Roc1bCG16988 gene product from transcript CG16988-RA0.087
CG7051CG7051 gene product from transcript CG7051-RA0.075
HtrA2CG8464 gene product from transcript CG8464-RA0.074
CG10630CG10630 gene product from transcript CG10630-RA0.060
trpmltransient receptor potential mucolipin0.058
comtcomatose0.057
PpcsPhosphopantothenoylcysteine synthetase0.056
Dcr-2Dicer-20.053
HLH106Helix loop helix protein 1060.051
eIF4E-3CG8023 gene product from transcript CG8023-RA0.049
Hsc70-5Heat shock protein cognate 50.040
p53CG33336 gene product from transcript CG33336-RB0.038
bdgbedraggled0.032
CG8709CG8709 gene product from transcript CG8709-RK0.030
betaTub85Dbeta-Tubulin at 85D0.030
Cdc37CG12019 gene product from transcript CG12019-RA0.029
stmAstambha A0.027
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.027
ref(2)Prefractory to sigma P0.025
mrnmarionette0.024
Nrx-1Neurexin 10.024
CG8443CG8443 gene product from transcript CG8443-RA0.024
ninaEneither inactivation nor afterpotential E0.023
dj-1betaCG1349 gene product from transcript CG1349-RA0.023
Act88FActin 88F0.022
AconAconitase0.022
mib2mind bomb 20.022
ruxroughex0.022
Vps28Vacuolar protein sorting 280.021
Ppat-DpckBifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase0.020
Drp1Dynamin related protein 10.019
Aats-serSeryl-tRNA synthetase0.019
SdhBSuccinate dehydrogenase B0.018
Sac1CG9128 gene product from transcript CG9128-RB0.018
DJ-1alphaCG6646 gene product from transcript CG6646-RA0.017
CbyChibby0.017
kermitCG11546 gene product from transcript CG11546-RB0.016
Ube3aUbiquitin protein ligase E3A0.016
MiroMitochondrial Rho0.016
CG4774CG4774 gene product from transcript CG4774-RB0.015
fblfumble0.015
CatCatalase0.014
Surf1Surfeit 10.014
miltmilton0.014
blwbellwether0.014
CG11876CG11876 gene product from transcript CG11876-RA0.013
jarjaguar0.013
Fer2LCHFerritin 2 light chain homologue0.013
CG32627CG32627 gene product from transcript CG32627-RA0.012
srasarah0.012
CG8728CG8728 gene product from transcript CG8728-RA0.012
SNF1ASNF1A/AMP-activated protein kinase0.012
CG8818CG8818 gene product from transcript CG8818-RA0.012
pex1peroxin 10.011
tefutelomere fusion0.011
RicRas which interacts with Calmodulin0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BCL2B-cell CLL/lymphoma 21.000
BCL2L1BCL2-like 10.999
BNIP3BCL2/adenovirus E1B 19kDa interacting protein 30.924
BCL2L11BCL2-like 11 (apoptosis facilitator)0.683
BAXBCL2-associated X protein0.428
MARCH5membrane-associated ring finger (C3HC4) 50.382
BNIP3LBCL2/adenovirus E1B 19kDa interacting protein 3-like0.286
BADBCL2-associated agonist of cell death0.281
RNR2l-rRNA0.151
FBXO7F-box protein 70.148
PMAIP1phorbol-12-myristate-13-acetate-induced protein 10.132
DNM2dynamin 20.094
WASLWiskott-Aldrich syndrome-like0.079
ZNF746zinc finger protein 7460.079
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.077
BIDBH3 interacting domain death agonist0.062
BCAP31B-cell receptor-associated protein 310.060
DNM1dynamin 10.060
BAK1BCL2-antagonist/killer 10.058
VDAC1voltage-dependent anion channel 10.050
AMPHamphiphysin0.038
RNF144Bring finger protein 144B0.032
TMEM11transmembrane protein 110.024
SNX33sorting nexin 330.024
NUDT3nudix (nucleoside diphosphate linked moiety X)-type motif 30.024
DBN1drebrin 10.022
PINK1PTEN induced putative kinase 10.022
BCL2L2BCL2-like 20.021
C4orf14chromosome 4 open reading frame 140.020
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.017
BIKBCL2-interacting killer (apoptosis-inducing)0.017
SNX9sorting nexin 90.016
UBASH3Aubiquitin associated and SH3 domain containing A0.015
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.014
ADAM15ADAM metallopeptidase domain 150.012
AIFM1apoptosis-inducing factor, mitochondrion-associated, 10.012
BBC3BCL2 binding component 30.012
DAP3death associated protein 30.011
BABAM1BRISC and BRCA1 A complex member 10.011
CCDC85Bcoiled-coil domain containing 85B0.011
MAP1LC3Bmicrotubule-associated protein 1 light chain 3 beta0.011
NBR1neighbor of BRCA1 gene 10.011
PACSIN2protein kinase C and casein kinase substrate in neurons 20.011
PDHXpyruvate dehydrogenase complex, component X0.011
CHPFchondroitin polymerizing factor0.010
UBASH3Bubiquitin associated and SH3 domain containing B0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
BaxBCL2-associated X protein1.000
Bcl2l11BCL2-like 11 (apoptosis facilitator)1.000
Bak1BCL2-antagonist/killer 11.000
Bcl2B-cell leukemia/lymphoma 20.996
Mfn2mitofusin 20.963
Trp53transformation related protein 530.468
Psma4proteasome (prosome, macropain) subunit, alpha type 40.386
Pmaip1phorbol-12-myristate-13-acetate-induced protein 10.361
Parlpresenilin associated, rhomboid-like0.192
Ighimmunoglobulin heavy chain complex0.115
Psmb2proteasome (prosome, macropain) subunit, beta type 20.106
Opa1optic atrophy 1 homolog (human)0.075
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.061
Kitkit oncogene0.052
Lrpprcleucine-rich PPR-motif containing0.051
Mrpl16mitochondrial ribosomal protein L160.043
Snrnp70small nuclear ribonucleoprotein 70 (U1)0.041
Sec13SEC13 homolog (S. cerevisiae)0.040
Mtormechanistic target of rapamycin (serine/threonine kinase)0.038
Hspa9heat shock protein 90.038
Ppm1bprotein phosphatase 1B, magnesium dependent, beta isoform0.037
Dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.035
Hmbshydroxymethylbilane synthase0.034
Eif2b1eukaryotic translation initiation factor 2B, subunit 1 (alpha)0.031
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.029
Immtinner membrane protein, mitochondrial0.029
Ikzf3IKAROS family zinc finger 30.028
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.027
U2af1U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 10.027
Nubp1nucleotide binding protein 10.026
NansN-acetylneuraminic acid synthase (sialic acid synthase)0.025
Psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.025
Park2Parkinson disease (autosomal recessive, juvenile) 2, parkin0.024
Psma7proteasome (prosome, macropain) subunit, alpha type 70.024
BidBH3 interacting domain death agonist0.023
Prmt1protein arginine N-methyltransferase 10.023
Arpc4actin related protein 2/3 complex, subunit 40.020
Fblfibrillarin0.019
Pdha1pyruvate dehydrogenase E1 alpha 10.019
Vaspvasodilator-stimulated phosphoprotein0.018
Pick1protein interacting with C kinase 10.018
Mrps23mitochondrial ribosomal protein S230.018
Pfdn2prefoldin 20.017
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.016
Cdk4cyclin-dependent kinase 40.015
Banf1barrier to autointegration factor 10.014
Idh3aisocitrate dehydrogenase 3 (NAD+) alpha0.014
Mrpl9mitochondrial ribosomal protein L90.014
Eif6eukaryotic translation initiation factor 60.012
Ewsr1Ewing sarcoma breakpoint region 10.012
Uqccubiquinol-cytochrome c reductase complex chaperone, CBP3 homolog (yeast)0.012
Iars2isoleucine-tRNA synthetase 2, mitochondrial0.012
Nit2nitrilase family, member 20.011
Huwe1HECT, UBA and WWE domain containing 10.011
Psmb6proteasome (prosome, macropain) subunit, beta type 60.011
Gfm1G elongation factor, mitochondrial 10.011
Srsf9serine/arginine-rich splicing factor 90.011
Coq7demethyl-Q 70.011
Srrtserrate RNA effector molecule homolog (Arabidopsis)0.010
Acin1apoptotic chromatin condensation inducer 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ltbrlymphotoxin beta receptor (TNFR superfamily, member 3)0.020
Grngranulin0.015
Dlstdihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)0.014
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism