The network for 'cellular response to inorganic substance' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to inorganic substance

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.

NameDescriptionProbabilityFunc Analog Organism
G-oalpha47AG protein oalpha 47A0.080
PHGPxCG12013 gene product from transcript CG12013-RC0.069
cicubitus interruptus0.037
CG5362CG5362 gene product from transcript CG5362-RA0.037
Rac1CG2248 gene product from transcript CG2248-RA0.033
Rho1CG8416 gene product from transcript CG8416-RB0.033
CG8446CG8446 gene product from transcript CG8446-RC0.030
Eaat1Excitatory amino acid transporter 10.025
ThorCG8846 gene product from transcript CG8846-RA0.021
faffat facets0.017
AldhAldehyde dehydrogenase0.015
CG2118CG2118 gene product from transcript CG2118-RB0.013
E(var)3-9Enhancer of variegation 3-90.011
Myd88CG2078 gene product from transcript CG2078-RA0.011
p120ctnAdherens junction protein p1200.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
cyp-35C1Protein CYP-35C10.650
cyp-35A2Protein CYP-35A20.499
cyp-35A3Protein CYP-35A30.498
cyp-35A5Protein CYP-35A50.307
pry-1Protein PRY-10.216
F13H6.3Protein F13H6.30.201
pkg-1Protein PKG-10.173
cyp-35A4Protein CYP-35A40.155
cdc-48.1Protein CDC-48.10.155
F48E8.6Protein F48E8.60.148
cwn-2Protein CWN-20.138
ugt-22Protein UGT-220.128
flt-1Protein FLT-10.098
acs-4Protein ACS-40.088
egl-18Protein EGL-180.084
rpn-1Protein RPN-10.084
cdf-1Protein CDF-10.082
grd-1Protein GRD-10.081
eat-6Protein EAT-60.075
kcc-2Protein KCC-20.075
F13B6.1Protein F13B6.10.074
F01G4.4Protein F01G4.40.072
CELE_ZK1025.3Protein ZK1025.30.072
scl-2Protein SCL-20.069
CELE_C29F7.2Protein C29F7.20.066
cutl-28Protein CUTL-280.061
T08G11.1Protein T08G11.10.060
dhc-1Protein DHC-10.057
mek-2Protein MEK-20.057
chc-1Protein CHC-10.057
acly-2Protein ACLY-20.056
cki-2Protein CKI-20.055
Y65A5A.1Protein Y65A5A.10.054
K03B8.6Protein K03B8.60.052
pmk-3Protein PMK-30.050
gpb-1Protein GPB-10.049
gpb-2Protein GPB-20.049
bli-1Protein BLI-10.047
CELE_T04A8.7Protein T04A8.70.046
lin-17Protein LIN-170.045
col-79Protein COL-790.044
axl-1Protein AXL-10.044
cec-1Protein CEC-10.043
ccz-1Protein CCZ-10.043
smp-1Protein SMP-10.042
dhs-16Protein DHS-160.041
C37H5.2Protein C37H5.20.041
grd-2Protein GRD-20.041
elt-6Protein ELT-60.040
CELE_Y11D7A.5Protein Y11D7A.50.040
cgef-2Protein CGEF-20.040
sdha-1Protein SDHA-10.039
eor-2Protein EOR-20.038
nhr-170Protein NHR-1700.038
R10E4.1Protein R10E4.10.038
dhs-21Protein DHS-210.038
CELE_C17H1.7Protein C17H1.70.038
B0035.12Protein B0035.120.038
C34D10.2Protein C34D10.20.038
par-5Protein PAR-50.038
CELE_T23F6.5Protein T23F6.50.038
C11E4.1Protein C11E4.10.037
wip-1Protein WIP-10.037
smf-1Protein SMF-10.037
lin-13Protein LIN-130.036
daf-12Protein DAF-120.036
F18A1.6Protein F18A1.60.036
T05A12.4Protein T05A12.40.036
ttm-2Protein TTM-20.036
T22F3.3Protein T22F3.30.035
rrc-1Protein RRC-10.035
madf-5Protein MADF-50.035
mig-17Protein MIG-170.034
R11A8.7Protein R11A8.70.034
lbp-7Protein LBP-70.034
dab-1Protein DAB-10.034
ilys-4Protein ILYS-40.033
sur-2Protein SUR-20.033
sago-2Protein SAGO-20.033
R07E4.5Protein R07E4.50.033
unc-41Protein UNC-410.033
C03A3.2Protein C03A3.20.033
vab-23Protein VAB-230.033
R07B1.7Protein R07B1.70.032
ima-3Protein IMA-30.032
C33G3.6Protein C33G3.60.032
egl-23Protein EGL-230.032
mth-1Protein MTH-10.032
fkh-2Protein FKH-20.031
F56A8.3Protein F56A8.30.031
W01A11.1Protein W01A11.10.031
trr-1Protein TRR-10.031
hlh-14Protein HLH-140.031
eea-1Protein EEA-10.031
ogt-1Protein OGT-10.031
CELE_C17F4.2Protein C17F4.20.030
sulp-2Protein SULP-20.030
nkcc-1Protein NKCC-10.030
npp-9Protein NPP-90.030
Y37A1A.3Protein Y37A1A.30.030
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
MT1Fmetallothionein 1F0.967
MT1Hmetallothionein 1H0.966
MT1Emetallothionein 1E0.950
MT1Xmetallothionein 1X0.933
ARRB1arrestin, beta 10.896
MT2Ametallothionein 2A0.883
JUNjun proto-oncogene0.737
HDAC4histone deacetylase 40.670
MT1Gmetallothionein 1G0.577
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.531
ATF2activating transcription factor 20.498
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.426
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 10.358
CDK2cyclin-dependent kinase 20.304
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.299
NOSTRINnitric oxide synthase trafficker0.282
MAPK1mitogen-activated protein kinase 10.253
SH3KBP1SH3-domain kinase binding protein 10.214
BNIP3BCL2/adenovirus E1B 19kDa interacting protein 30.211
DUSP1dual specificity phosphatase 10.210
PTPRJprotein tyrosine phosphatase, receptor type, J0.205
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.192
CREBBPCREB binding protein0.172
COTL1coactosin-like 1 (Dictyostelium)0.171
FOSFBJ murine osteosarcoma viral oncogene homolog0.167
KAT2BK(lysine) acetyltransferase 2B0.154
MAPK14mitogen-activated protein kinase 140.150
MAP2K4mitogen-activated protein kinase kinase 40.147
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.146
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.141
APPamyloid beta (A4) precursor protein0.138
GPR50G protein-coupled receptor 500.135
BNIP3LBCL2/adenovirus E1B 19kDa interacting protein 3-like0.128
CITED2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.125
DLG4discs, large homolog 4 (Drosophila)0.123
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.114
ATF3activating transcription factor 30.113
HNF4Ahepatocyte nuclear factor 4, alpha0.108
PPARGperoxisome proliferator-activated receptor gamma0.091
HSPA1Bheat shock 70kDa protein 1B0.090
MAPTmicrotubule-associated protein tau0.089
PLAUplasminogen activator, urokinase0.089
DSG2desmoglein 20.087
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.084
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.083
SNTA1syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)0.081
MAPK15mitogen-activated protein kinase 150.081
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.078
NCOA3nuclear receptor coactivator 30.077
EP300E1A binding protein p3000.075
NCOA1nuclear receptor coactivator 10.070
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.067
PPP1R15Aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.063
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.059
SNTG2syntrophin, gamma 20.057
MT1Mmetallothionein 1M0.057
CCNA2cyclin A20.057
YY1YY1 transcription factor0.056
GADD45Bgrowth arrest and DNA-damage-inducible, beta0.055
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta0.055
AKT1v-akt murine thymoma viral oncogene homolog 10.054
TP53tumor protein p530.054
JUNDjun D proto-oncogene0.052
MAP2K1mitogen-activated protein kinase kinase 10.051
MT1Bmetallothionein 1B0.051
RB1retinoblastoma 10.049
GRIN2Cglutamate receptor, ionotropic, N-methyl D-aspartate 2C0.049
PMLpromyelocytic leukemia0.048
PTCHD2patched domain containing 20.048
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.048
NCOA2nuclear receptor coactivator 20.047
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.047
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.047
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma0.047
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.047
LRP6low density lipoprotein receptor-related protein 60.046
IER2immediate early response 20.046
FOXO3forkhead box O30.045
EGR1early growth response 10.045
SPTBN1spectrin, beta, non-erythrocytic 10.044
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.044
SKP2S-phase kinase-associated protein 2 (p45)0.043
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 50.042
HGFhepatocyte growth factor (hepapoietin A; scatter factor)0.040
RARAretinoic acid receptor, alpha0.039
TRAF1TNF receptor-associated factor 10.038
CYR61cysteine-rich, angiogenic inducer, 610.038
ESRRGestrogen-related receptor gamma0.038
EFEMP2EGF containing fibulin-like extracellular matrix protein 20.038
KRT5keratin 50.038
P4HBprolyl 4-hydroxylase, beta polypeptide0.037
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.037
CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 60.036
CD80CD80 molecule0.035
MAP2K6mitogen-activated protein kinase kinase 60.035
BRCA1breast cancer 1, early onset0.035
CHAF1Achromatin assembly factor 1, subunit A (p150)0.034
SOCS3suppressor of cytokine signaling 30.034
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Mapk14mitogen-activated protein kinase 140.841
Vdrvitamin D receptor0.774
Tgfb1transforming growth factor, beta 10.770
Mt2metallothionein 20.765
Csf1colony stimulating factor 1 (macrophage)0.752
JunJun oncogene0.752
Mt1metallothionein 10.744
Nfe2l2nuclear factor, erythroid derived 2, like 20.710
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.703
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.697
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.640
Ptpn11protein tyrosine phosphatase, non-receptor type 110.631
Ppargperoxisome proliferator activated receptor gamma0.606
Cyp2c29cytochrome P450, family 2, subfamily c, polypeptide 290.590
Stat3signal transducer and activator of transcription 30.590
Cps1carbamoyl-phosphate synthetase 10.570
Ascl1achaete-scute complex homolog 1 (Drosophila)0.563
Myf5myogenic factor 50.555
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.553
Cyp2c38cytochrome P450, family 2, subfamily c, polypeptide 380.550
Gsk3bglycogen synthase kinase 3 beta0.549
Col1a1collagen, type I, alpha 10.539
Mapk8mitogen-activated protein kinase 80.506
FosFBJ osteosarcoma oncogene0.497
Ptgs2prostaglandin-endoperoxide synthase 20.493
Aadacarylacetamide deacetylase (esterase)0.492
Hif1ahypoxia inducible factor 1, alpha subunit0.488
Egr1early growth response 10.485
Arandrogen receptor0.473
Nhlh1nescient helix loop helix 10.467
Thbs1thrombospondin 10.466
Myod1myogenic differentiation 10.457
Tcf3transcription factor 30.454
Smad3MAD homolog 3 (Drosophila)0.453
MecomMDS1 and EVI1 complex locus0.441
Nos1nitric oxide synthase 1, neuronal0.439
Rdh7retinol dehydrogenase 70.436
Runx2runt related transcription factor 20.435
Ctnnb1catenin (cadherin associated protein), beta 10.423
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.418
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.414
Atf2activating transcription factor 20.413
Thrathyroid hormone receptor alpha0.405
Ighimmunoglobulin heavy chain complex0.403
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.401
Ptenphosphatase and tensin homolog0.385
Hrghistidine-rich glycoprotein0.376
Lyz2lysozyme 20.371
Hnf4ahepatic nuclear factor 4, alpha0.363
Krt8keratin 80.360
Chordc1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 10.358
Ror2receptor tyrosine kinase-like orphan receptor 20.358
Cyp3a11cytochrome P450, family 3, subfamily a, polypeptide 110.344
Krt72-pskeratin 72, pseudogene0.342
Trp53transformation related protein 530.336
Mecp2methyl CpG binding protein 20.325
Mdm2transformed mouse 3T3 cell double minute 20.320
Rb1retinoblastoma 10.306
Krt7keratin 70.303
Notch2Notch gene homolog 2 (Drosophila)0.292
Myd88myeloid differentiation primary response gene 880.278
Cd44CD44 antigen0.273
Nr5a2nuclear receptor subfamily 5, group A, member 20.270
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.265
Cav1caveolin 1, caveolae protein0.259
Cyp2b9cytochrome P450, family 2, subfamily b, polypeptide 90.256
Hdac4histone deacetylase 40.250
Hsd3b3hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 30.246
Prph2peripherin 20.246
Dctdopachrome tautomerase0.242
Neurod1neurogenic differentiation 10.241
Cyp4a14cytochrome P450, family 4, subfamily a, polypeptide 140.236
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.236
Apohapolipoprotein H0.235
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.235
Lect2leukocyte cell-derived chemotaxin 20.234
Mknk2MAP kinase-interacting serine/threonine kinase 20.231
Axin1axin 10.230
Krt5keratin 50.227
Serpina6serine (or cysteine) peptidase inhibitor, clade A, member 60.225
Glipr2GLI pathogenesis-related 20.223
Akr1c6aldo-keto reductase family 1, member C60.219
Egfrepidermal growth factor receptor0.216
Krt14keratin 140.214
Pitx1paired-like homeodomain transcription factor 10.208
Lmnalamin A0.206
Siglec5sialic acid binding Ig-like lectin 50.206
Cyp2d10cytochrome P450, family 2, subfamily d, polypeptide 100.205
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.201
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.200
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.197
Nr1i3nuclear receptor subfamily 1, group I, member 30.193
Atf3activating transcription factor 30.193
Elovl3elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 30.188
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.180
Maffv-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)0.178
Elf3E74-like factor 30.177
Uoxurate oxidase0.173
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Akr1c18aldo-keto reductase family 1, member C180.036
Mgst1microsomal glutathione S-transferase 10.031
LOC100364265ribosomal protein L19-like0.031
Plaurplasminogen activator, urokinase receptor0.029
Defb4defensin beta 40.029
Atxn1ataxin 10.029
Fut1fucosyltransferase 10.027
Clcnkachloride channel Ka0.027
Clcn5chloride channel 50.026
Pipprolactin induced protein0.026
Dusp1dual specificity phosphatase 10.025
Cdkn3cyclin-dependent kinase inhibitor 30.025
Cd80Cd80 molecule0.024
Timp1TIMP metallopeptidase inhibitor 10.023
Vipvasoactive intestinal peptide0.023
Gstm1glutathione S-transferase mu 10.022
Tsxtestis specific X-linked gene0.022
Sisucrase-isomaltase (alpha-glucosidase)0.021
Vtcn1V-set domain containing T cell activation inhibitor 10.021
Aqp8aquaporin 80.021
Atf3activating transcription factor 30.021
Olfml2bolfactomedin-like 2B0.021
Vom1r101vomeronasal 1 receptor 1010.021
Klk8kallikrein related-peptidase 80.020
Strapserine/threonine kinase receptor associated protein0.020
Slc6a17solute carrier family 6 (neurotransmitter transporter), member 170.020
Ucp1uncoupling protein 1 (mitochondrial, proton carrier)0.020
Ceacam11carcinoembryonic antigen-related cell adhesion molecule 110.020
Cd46CD46 molecule, complement regulatory protein0.020
Starsteroidogenic acute regulatory protein0.020
St18suppression of tumorigenicity 180.020
Ece1endothelin converting enzyme 10.020
Cd14CD14 molecule0.020
Pgrprogesterone receptor0.020
C1rcomplement component 1, r subcomponent0.020
Ftlferritin, light polypeptide0.020
Prl3d4prolactin family 3, subfamily d, member 40.020
Nr1h4nuclear receptor subfamily 1, group H, member 40.019
Hspb1heat shock protein 10.019
Timp2TIMP metallopeptidase inhibitor 20.019
Klf6Kruppel-like factor 60.019
Scn8asodium channel, voltage gated, type VIII, alpha subunit0.019
Gjb3gap junction protein, beta 30.019
Cyp2d2cytochrome P450, family 2, subfamily d, polypeptide 20.019
Olr1496olfactory receptor 14960.019
Npffr2neuropeptide FF receptor 20.019
Fkbp4FK506 binding protein 40.019
Serpina5serine (or cysteine) peptidase inhibitor, clade A, member 50.018
Rup2urinary protein 20.018
Fgf16fibroblast growth factor 160.018
Shox2short stature homeobox 20.018
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.018
Coro1bcoronin, actin-binding protein, 1B0.018
Gpr6G protein-coupled receptor 60.018
Pfkfb36-phosphofructo-2-kinase/fructose-2,6-biphosphatase 30.018
Foxi2forkhead box I20.018
Gpihbp1glycosylphosphatidylinositol anchored high density lipoprotein binding protein 10.018
Ephx1epoxide hydrolase 1, microsomal0.017
Mmp12matrix metallopeptidase 120.017
Adrb1adrenergic, beta-1-, receptor0.017
Prkacbprotein kinase, cAMP dependent, catalytic, beta0.017
Morf4l2mortality factor 4 like 20.017
Cxcl3chemokine (C-X-C motif) ligand 30.017
Htr1f5-hydroxytryptamine (serotonin) receptor 1F0.017
Apoc4apolipoprotein C-IV0.017
Egr2early growth response 20.017
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.017
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.017
Acvr1cactivin A receptor, type IC0.017
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.017
MosMoloney sarcoma oncogene0.017
JunJun oncogene0.017
Inhbainhibin beta-A0.017
Hoxd9homeo box D90.017
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.017
Ptgs2prostaglandin-endoperoxide synthase 20.017
Dhdpsldihydrodipicolinate synthase-like, mitochondrial0.016
Phexphosphate regulating endopeptidase homolog, X-linked0.016
Slc30a2solute carrier family 30 (zinc transporter), member 20.016
Sftpdsurfactant protein D0.016
Adrb3adrenergic, beta-3-, receptor0.016
Stip1stress-induced phosphoprotein 10.016
Exoc5exocyst complex component 50.016
Egr1early growth response 10.016
Mmp8matrix metallopeptidase 80.016
Atp2c2ATPase, Ca++ transporting, type 2C, member 20.016
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.016
Ube2d4ubiquitin-conjugating enzyme E2D 40.016
Muskmuscle, skeletal, receptor tyrosine kinase0.016
Slc8a1solute carrier family 8 (sodium/calcium exchanger), member 10.016
Fosl1fos-like antigen 10.016
Lbplipopolysaccharide binding protein0.016
Mgst2microsomal glutathione S-transferase 20.016
C1qbcomplement component 1, q subcomponent, B chain0.016
Ppp2r2aprotein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform0.016
Megf6multiple EGF-like-domains 60.016
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
YPL014Whypothetical protein0.013
YKR075Chypothetical protein0.010