The network for 'steroid catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

steroid catabolic process

The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

NameDescriptionProbabilityFunc Analog Organism
Ugt35aUDP-glycosyltransferase 35a0.970
Cyp12a4CG6042 gene product from transcript CG6042-RA0.895
Cyp6a23CG10242 gene product from transcript CG10242-RA0.895
CG13310CG13310 gene product from transcript CG13310-RA0.837
Cyp4ac1CG14032 gene product from transcript CG14032-RA0.830
Cyp6a21CG10247 gene product from transcript CG10247-RA0.745
Cyp12e1CG14680 gene product from transcript CG14680-RC0.711
Cyp6d5CG3050 gene product from transcript CG3050-RA0.694
CG18522CG18522 gene product from transcript CG18522-RA0.677
Cyp9b2Cytochrome P450-9b20.529
Cyp6a9Cytochrome P450-6a90.492
CG6834CG6834 gene product from transcript CG6834-RA0.473
Cyp6d4CG12800 gene product from transcript CG12800-RA0.471
CG6830CG6830 gene product from transcript CG6830-RA0.467
Cyp6a13CG2397 gene product from transcript CG2397-RA0.453
CG10562CG10562 gene product from transcript CG10562-RA0.445
Cyp28d1CG10833 gene product from transcript CG10833-RA0.381
CG9510CG9510 gene product from transcript CG9510-RC0.345
Cyp9f2CG11466 gene product from transcript CG11466-RB0.343
CG3759CG3759 gene product from transcript CG3759-RB0.342
Cyp6a2Cytochrome P450-6a20.335
CG9360CG9360 gene product from transcript CG9360-RA0.334
Cyp12a5CG11821 gene product from transcript CG11821-RA0.331
CG1927CG1927 gene product from transcript CG1927-RA0.331
Ser7CG2045 gene product from transcript CG2045-RA0.328
CG10550CG10550 gene product from transcript CG10550-RB0.318
JhI-26Juvenile hormone-inducible protein 260.317
dibdisembodied0.312
Cyp4e2Cytochrome P450-4e20.287
CG2064CG2064 gene product from transcript CG2064-RA0.275
LvpDLarval visceral protein D0.243
EpacCG34392 gene product from transcript CG34392-RC0.242
Ugt36BcCG17932 gene product from transcript CG17932-RB0.228
CG10560CG10560 gene product from transcript CG10560-RA0.223
CG6908CG6908 gene product from transcript CG6908-RA0.223
Cyp6a22CG10240 gene product from transcript CG10240-RA0.211
CG3902CG3902 gene product from transcript CG3902-RA0.200
CG5335CG5335 gene product from transcript CG5335-RA0.197
TgTransglutaminase0.192
CG14457CG14457 gene product from transcript CG14457-RA0.189
Ugt86DaCG18578 gene product from transcript CG18578-RA0.185
CG6045CG6045 gene product from transcript CG6045-RA0.184
Cyp28a5CG8864 gene product from transcript CG8864-RA0.183
CG10979CG10979 gene product from transcript CG10979-RA0.172
Est-QEsterase Q0.170
CG9331CG9331 gene product from transcript CG9331-RF0.163
alpha-Est7alpha-Esterase-70.160
CG4332CG4332 gene product from transcript CG4332-RA0.155
CG12672CG12672 gene product from transcript CG12672-RA0.151
CG16898CG16898 gene product from transcript CG16898-RA0.144
Cyp6w1CG8345 gene product from transcript CG8345-RA0.142
shdshade0.136
CG5819CG5819 gene product from transcript CG5819-RA0.133
fuslfuseless0.126
Ilp4Insulin-like peptide 40.124
CG9628CG9628 gene product from transcript CG9628-RA0.122
Cyp4ac3CG14031 gene product from transcript CG14031-RA0.122
CG11149CG11149 gene product from transcript CG11149-RD0.120
nimB2nimrod B20.120
CG15408CG15408 gene product from transcript CG15408-RA0.120
Ugt86DhCG4772 gene product from transcript CG4772-RA0.118
TotATurandot A0.117
CG5361CG5361 gene product from transcript CG5361-RA0.114
CG13658CG13658 gene product from transcript CG13658-RB0.113
CG31958CG31958 gene product from transcript CG31958-RA0.113
CG15784CG15784 gene product from transcript CG15784-RA0.111
CG15661CG15661 gene product from transcript CG15661-RA0.110
CG11967CG11967 gene product from transcript CG11967-RA0.109
Jheh1Juvenile hormone epoxide hydrolase 10.107
CG4302CG4302 gene product from transcript CG4302-RA0.106
Cyp4e1Cytochrome P450-4e10.106
CG17664CG17664 gene product from transcript CG17664-RA0.106
Cyp9h1CG17577 gene product from transcript CG17577-RA0.105
CG5999CG5999 gene product from transcript CG5999-RB0.104
Cyp4p1Cytochrome P450-4p10.104
Cyp12d1-pCG30489 gene product from transcript CG30489-RA0.104
CG12746CG12746 gene product from transcript CG12746-RD0.102
Jheh3Juvenile hormone epoxide hydrolase 30.101
CG16965CG16965 gene product from transcript CG16965-RB0.101
CG10226CG10226 gene product from transcript CG10226-RA0.100
CG12140CG12140 gene product from transcript CG12140-RA0.100
CG3301CG3301 gene product from transcript CG3301-RB0.099
glob1globin 10.098
nAcRalpha-96Aanicotinic Acetylcholine Receptor alpha 96Aa0.096
CG15828CG15828 gene product from transcript CG15828-RC0.096
CG4721CG4721 gene product from transcript CG4721-RA0.095
Fkbp13CG9847 gene product from transcript CG9847-RC0.095
CG18507CG18507 gene product from transcript CG18507-RB0.095
aralar1CG2139 gene product from transcript CG2139-RC0.095
CG4653CG4653 gene product from transcript CG4653-RA0.094
CG4630CG4630 gene product from transcript CG4630-RA0.094
CG14528CG14528 gene product from transcript CG14528-RA0.093
Est-6Esterase 60.093
CG15611CG15611 gene product from transcript CG15611-RB0.090
Ugt86DjCG15902 gene product from transcript CG15902-RA0.090
CG11426CG11426 gene product from transcript CG11426-RA0.090
Cyp12d1-dCG33503 gene product from transcript CG33503-RA0.089
Osi6Osiris 60.088
CG6579CG6579 gene product from transcript CG6579-RB0.088
CG3714CG3714 gene product from transcript CG3714-RC0.088
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide1.000
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide1.000
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide1.000
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.938
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.832
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.717
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.676
A2Malpha-2-macroglobulin0.655
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.557
CYP3A7cytochrome P450, family 3, subfamily A, polypeptide 70.418
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.408
APOC1apolipoprotein C-I0.219
SFNstratifin0.071
HPhaptoglobin0.068
CYP3A5cytochrome P450, family 3, subfamily A, polypeptide 50.061
CYP3A43cytochrome P450, family 3, subfamily A, polypeptide 430.060
CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 90.051
CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 40.044
PRMT2protein arginine methyltransferase 20.042
GABRA3gamma-aminobutyric acid (GABA) A receptor, alpha 30.041
NUDT18nudix (nucleoside diphosphate linked moiety X)-type motif 180.037
CDC25Bcell division cycle 25 homolog B (S. pombe)0.033
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.025
HDAC4histone deacetylase 40.024
TSC2tuberous sclerosis 20.020
CYP2B6cytochrome P450, family 2, subfamily B, polypeptide 60.018
F9coagulation factor IX0.017
CYP4A11cytochrome P450, family 4, subfamily A, polypeptide 110.016
PRDX1peroxiredoxin 10.016
CYP4F12cytochrome P450, family 4, subfamily F, polypeptide 120.014
PLTPphospholipid transfer protein0.013
WDYHV1WDYHV motif containing 10.012
C8Acomplement component 8, alpha polypeptide0.011
URODuroporphyrinogen decarboxylase0.011
JUPjunction plakoglobin0.011
MAP3K3mitogen-activated protein kinase kinase kinase 30.011
MAPTmicrotubule-associated protein tau0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Apoeapolipoprotein E0.654
Leprleptin receptor0.447
Otcornithine transcarbamylase0.153
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.136
Cyp3a25cytochrome P450, family 3, subfamily a, polypeptide 250.118
Agtr1aangiotensin II receptor, type 1a0.101
Cyp8b1cytochrome P450, family 8, subfamily b, polypeptide 10.089
Slc12a1solute carrier family 12, member 10.071
Cyp2c38cytochrome P450, family 2, subfamily c, polypeptide 380.051
F12coagulation factor XII (Hageman factor)0.038
Cyp4a14cytochrome P450, family 4, subfamily a, polypeptide 140.038
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.036
Apobapolipoprotein B0.033
G6pcglucose-6-phosphatase, catalytic0.031
F13bcoagulation factor XIII, beta subunit0.025
Apoa2apolipoprotein A-II0.023
Nr1i2nuclear receptor subfamily 1, group I, member 20.021
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.020
Cps1carbamoyl-phosphate synthetase 10.020
Cyp2c50cytochrome P450, family 2, subfamily c, polypeptide 500.019
Cyp2d10cytochrome P450, family 2, subfamily d, polypeptide 100.018
Ldlrlow density lipoprotein receptor0.017
Aldobaldolase B, fructose-bisphosphate0.017
Cyp2d9cytochrome P450, family 2, subfamily d, polypeptide 90.017
Abcc2ATP-binding cassette, sub-family C (CFTR/MRP), member 20.016
Spp2secreted phosphoprotein 20.016
Baatbile acid-Coenzyme A: amino acid N-acyltransferase0.015
Umoduromodulin0.014
Cyp2a12cytochrome P450, family 2, subfamily a, polypeptide 120.014
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.013
Angptl4angiopoietin-like 40.013
Klk1b4kallikrein 1-related pepidase b40.013
Cfhcomplement component factor h0.013
Wnk4WNK lysine deficient protein kinase 40.013
Gcgroup specific component0.012
Scd1stearoyl-Coenzyme A desaturase 10.011
Fbn1fibrillin 10.011
Cyp2b9cytochrome P450, family 2, subfamily b, polypeptide 90.011
Lpllipoprotein lipase0.011
Fabp1fatty acid binding protein 1, liver0.011
Apoa1apolipoprotein A-I0.011
Mt1metallothionein 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.679
Ugt2b5UDP glucuronosyltransferase 2 family, polypeptide B50.658
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.616
Ugt2b37UDP-glucuronosyltransferase 2 family, member 370.486
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.451
Sult2al1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 10.435
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.303
Mgst2microsomal glutathione S-transferase 20.264
LOC100361547Cytochrome P450, family 2, subfamily c, polypeptide 7-like0.261
LOC293989cytochrome P450-like0.203
Ugt1a5UDP glucuronosyltransferase 1 family, polypeptide A50.141
Sult2a1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 10.135
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.126
Cyp2b2cytochrome P450, family 2, subfamily b, polypeptide 20.090
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.084
Ugt1a3UDP glycosyltransferase 1 family, polypeptide A30.080
Cyp2c11cytochrome P450, subfamily 2, polypeptide 110.075
Cyp2b1cytochrome P450, family 2, subfamily b, polypeptide 10.067
Cyp2a2cytochrome P450, family 2, subfamily a, polypeptide 20.061
Akr1d1aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)0.050
Cyp3a9cytochrome P450, family 3, subfamily a, polypeptide 90.050
Slco1a1solute carrier organic anion transporter family, member 1a10.044
LOC494499LOC494499 protein0.040
Ugt1a1UDP glucuronosyltransferase 1 family, polypeptide A10.039
Abcc2ATP-binding cassette, subfamily C (CFTR/MRP), member 20.034
Ugt1a7cUDP glucuronosyltransferase 1 family, polypeptide A7C0.032
Il1ainterleukin 1 alpha0.030
Ugt2b36UDP glucuronosyltransferase 2 family, polypeptide B360.029
Cyp4f4cytochrome P450, family 4, subfamily f, polypeptide 40.028
LOC100365112carboxylesterase-like0.027
Olr1346olfactory receptor 13460.027
Cyp2b15cytochrome P450, family 2, subfamily b, polypeptide 150.026
Mbl2mannose-binding lectin (protein C) 20.024
Crygfcrystallin, gamma F0.021
Abcb11ATP-binding cassette, subfamily B (MDR/TAP), member 110.021
Apobapolipoprotein B0.020
Cyp3a23/3a1cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 10.020
Cyp2c13cytochrome P450, family 2, subfamily c, polypeptide 130.018
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.018
Olr1280olfactory receptor 12800.017
Olr1366olfactory receptor 13660.016
Sdsserine dehydratase0.015
Sult1e1sulfotransferase family 1E, estrogen-preferring, member 10.015
Pigrpolymeric immunoglobulin receptor0.014
Aqp9aquaporin 90.013
Cyp4a2cytochrome P450, family 4, subfamily a, polypeptide 20.013
Olr1356olfactory receptor 13560.012
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.012
Akr1c14aldo-keto reductase family 1, member C140.012
Cyp7a1cytochrome P450, family 7, subfamily a, polypeptide 10.011
Amy2amylase 2, pancreatic0.011
Acsm2acyl-CoA synthetase medium-chain family member 20.011
Pcdhga11protocadherin gamma subfamily A, 110.011
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.011
Mug1murinoglobulin 10.011
Obp1fodorant binding protein I f0.011
LOC100361864UDP-glucuronosyltransferase 2B3-like0.010
L3mbtl3l(3)mbt-like 3 (Drosophila)0.010
Cyp2c12cytochrome P450, family 2, subfamily c, polypeptide 120.010
RGD1559532RGD15595320.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism