The network for 'histone h4 k20 methylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

histone h4 k20 methylation

The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone.

Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Su(var)205Suppressor of variegation 2050.578
wocwithout children0.125
Dim1CG3058 gene product from transcript CG3058-RA0.107
skpACG16983 gene product from transcript CG16983-RD0.107
Rpd3CG7471 gene product from transcript CG7471-RA0.093
Snr1Snf5-related 10.091
His2AvHistone H2A variant0.086
Su(var)3-7Suppressor of variegation 3-70.082
Su(var)2-HP2CG12864 gene product from transcript CG12864-RB0.079
barrbarren0.063
dupdouble parked0.062
ash1absent, small, or homeotic discs 10.053
MRG15CG6363 gene product from transcript CG6363-RA0.050
BEAF-32Boundary element-associated factor of 32kD0.050
D1D1 chromosomal protein0.048
Nf-YBNuclear factor Y-box B0.041
Su(var)2-10Suppressor of variegation 2-100.039
pds5CG17509 gene product from transcript CG17509-RA0.030
CTCFCG8591 gene product from transcript CG8591-RA0.026
trrtrithorax-related0.025
snamasomething that sticks like glue0.023
kin17CG5649 gene product from transcript CG5649-RA0.021
IswiImitation SWI0.020
CG10188CG10188 gene product from transcript CG10188-RB0.020
Chd1Chromodomain-helicase-DNA-binding protein 10.018
rad50CG6339 gene product from transcript CG6339-RD0.018
reptreptin0.018
HP1bCG7041 gene product from transcript CG7041-RA0.018
jumujumeau0.018
SuURSuppressor of Under-Replication0.017
Hel25EHelicase at 25E0.017
pzgputzig0.016
Cap-GCG34438 gene product from transcript CG34438-RF0.014
Pp1-87BProtein phosphatase 1 at 87B0.014
PcPolycomb0.014
Caf1-180CG12109 gene product from transcript CG12109-RB0.013
eggeggless0.013
polyCG9829 gene product from transcript CG9829-RB0.013
cavcaravaggio0.013
RgaRegena0.013
Cenp-CCG31258 gene product from transcript CG31258-RA0.013
Spt5CG7626 gene product from transcript CG7626-RA0.012
CG5934CG5934 gene product from transcript CG5934-RA0.012
CG9422CG9422 gene product from transcript CG9422-RA0.012
E(bx)Enhancer of bithorax0.012
SetCG4299 gene product from transcript CG4299-RA0.012
Uch-L3Ubiquitin C-terminal hydrolase0.012
PnnPinin0.012
CG13298CG13298 gene product from transcript CG13298-RA0.011
SRm160CG11274 gene product from transcript CG11274-RA0.011
Df31Decondensation factor 310.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
mll4bmyeloid/lymphoid or mixed-lineage leukemia 4b0.970
ehmt1beuchromatic histone-lysine N-methyltransferase 1b0.889
whsc1l1Wolf-Hirschhorn syndrome candidate 1-like 10.729
mll4amyeloid/lymphoid or mixed-lineage leukemia 4a0.709
prdm11PR domain containing 110.688
ehmt1aeuchromatic histone-lysine N-methyltransferase 1a0.684
prdm2bPR domain containing 2, with ZNF domain b0.656
setd2SET domain containing 20.604
setdb1aSET domain, bifurcated 1a0.553
setdb1bSET domain, bifurcated 1b0.493
mll2myeloid/lymphoid or mixed-lineage leukemia 20.470
ezh2enhancer of zeste homolog 2 (Drosophila)0.464
smyd5SMYD family member 50.423
setd8bSET domain containing (lysine methyltransferase) 8b0.363
whsc1Wolf-Hirschhorn syndrome candidate 10.360
suv420h2suppressor of variegation 4-20 homolog 2 (Drosophila)0.359
prdm8bPR domain containing 8b0.321
LOC567638hypothetical LOC5676380.285
suv39h1bsuppressor of variegation 3-9 homolog 1b0.267
setd8aSET domain containing (lysine methyltransferase) 8a0.263
prdm4PR domain containing 40.244
setd5SET domain containing 50.176
ehmt2euchromatic histone-lysine N-methyltransferase 20.154
prdm9PR domain containing 90.153
usp1ubiquitin specific protease 10.148
smyd3SET and MYND domain containing 30.131
lmnb1lamin B10.130
hcfc1ahost cell factor C1a0.124
wu:fi25h02wu:fi25h020.114
rif1RAP1 interacting factor homolog (yeast)0.107
ilf3ainterleukin enhancer binding factor 3a0.097
prdm1bPR domain containing 1b, with ZNF domain0.095
tra2btransformer 2 beta homolog (Drosophila)0.082
prdm14PR domain containing 140.077
nsd1bnuclear receptor binding SET domain protein 1b0.074
cbx1achromobox homolog 1a (HP1 beta homolog Drosophila)0.068
si:dkey-21n12.1si:dkey-21n12.10.055
tcea1transcription elongation factor A (SII), 10.050
zgc:154063zgc:1540630.044
suv420h1suppressor of variegation 4-20 homolog 1 (Drosophila)0.044
setd6SET domain containing 60.042
si:dkey-181m9.9si:dkey-181m9.90.039
snrpasmall nuclear ribonucleoprotein polypeptide A0.039
znf346zinc finger protein 3460.037
smyd2aSET and MYND domain containing 2a0.029
sephs1selenophosphate synthetase 10.027
nktrnatural killer-tumor recognition sequence0.027
tmf1TATA element modulatory factor 10.027
anp32aacidic (leucine-rich) nuclear phosphoprotein 32 family, member A0.026
slbpstem-loop binding protein0.025
pnnpinin, desmosome associated protein0.024
cnn3bcalponin 3, acidic b0.023
zgc:55701zgc:557010.022
zgc:66100zgc:661000.022
ppm1gprotein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform0.021
rbbp6retinoblastoma binding protein 60.021
cbx2chromobox homolog 2 (Drosophila Pc class)0.020
h3f3aH3 histone, family 3A0.019
rtf1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.018
wdr82WD repeat domain containing 820.017
ankrd12ankyrin repeat domain 120.017
rtkn2rhotekin 20.015
si:ch211-57k11.10si:ch211-57k11.100.015
med25mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)0.015
hp1bp3heterochromatin protein 1, binding protein 30.014
nkd2naked cuticle homolog 2 and naked 2a0.014
upf3bUPF3 regulator of nonsense transcripts homolog B (yeast)0.014
zgc:136346zgc:1363460.014
zgc:55468zgc:554680.014
ints2integrator complex subunit 20.013
churc1churchill domain containing 10.013
krcpkelch repeat-containing protein0.013
arglu1barginine and glutamate rich 1b0.013
si:ch211-198a12.6si:ch211-198a12.60.013
dpf2lD4, zinc and double PHD fingers family 2, like0.013
ppm1aaprotein phosphatase, Mg2+/Mn2+ dependent, 1Aa0.012
letm1leucine zipper-EF-hand containing transmembrane protein 10.011
vps26bvacuolar protein sorting 26 homolog B0.011
papolgpoly(A) polymerase gamma0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CBX5chromobox homolog 50.979
LBRlamin B receptor0.299
NBNnibrin0.211
ADNPactivity-dependent neuroprotector homeobox0.100
FANCD2Fanconi anemia, complementation group D20.097
CHAF1Achromatin assembly factor 1, subunit A (p150)0.084
HIST1H3Bhistone cluster 1, H3b0.054
POGZpogo transposable element with ZNF domain0.045
TP53BP1tumor protein p53 binding protein 10.040
TOP1topoisomerase (DNA) I0.038
ARID4AAT rich interactive domain 4A (RBP1-like)0.037
NSL1NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)0.033
MDC1mediator of DNA-damage checkpoint 10.031
RBBP4retinoblastoma binding protein 40.030
TWIST1twist homolog 1 (Drosophila)0.023
INCENPinner centromere protein antigens 135/155kDa0.021
ANKRD12ankyrin repeat domain 120.020
RFPL1ret finger protein-like 10.018
CBX1chromobox homolog 10.017
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)0.013
HDAC1histone deacetylase 10.013
MBD1methyl-CpG binding domain protein 10.011
ANP32Eacidic (leucine-rich) nuclear phosphoprotein 32 family, member E0.011
H2AFXH2A histone family, member X0.011
ADNP2ADNP homeobox 20.011
SGOL1shugoshin-like 1 (S. pombe)0.011
C5orf41chromosome 5 open reading frame 410.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trim24tripartite motif-containing 240.447
Brca2breast cancer 20.266
Kdm2blysine (K)-specific demethylase 2B0.259
Mll3myeloid/lymphoid or mixed-lineage leukemia 30.221
Trp53transformation related protein 530.124
Klhl24kelch-like 24 (Drosophila)0.104
Mdm2transformed mouse 3T3 cell double minute 20.097
Atrxalpha thalassemia/mental retardation syndrome X-linked homolog (human)0.093
BrafBraf transforming gene0.084
Apcadenomatosis polyposis coli0.082
RictorRPTOR independent companion of MTOR, complex 20.073
Rbm5RNA binding motif protein 50.071
Chd4chromodomain helicase DNA binding protein 40.057
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.057
Atmataxia telangiectasia mutated homolog (human)0.047
Chaf1achromatin assembly factor 1, subunit A (p150)0.046
Ezh2enhancer of zeste homolog 2 (Drosophila)0.044
Zmym5zinc finger, MYM-type 50.040
Rsf1remodeling and spacing factor 10.038
Tnrc6btrinucleotide repeat containing 6b0.037
2810474O19RikRIKEN cDNA 2810474O19 gene0.037
Xrn15'-3' exoribonuclease 10.034
Mll1myeloid/lymphoid or mixed-lineage leukemia 10.031
Trim28tripartite motif-containing 280.031
Dnmt1DNA methyltransferase (cytosine-5) 10.029
Hmgb1high mobility group box 10.029
Ankrd12ankyrin repeat domain 120.028
Phippleckstrin homology domain interacting protein0.027
Akap9A kinase (PRKA) anchor protein (yotiao) 90.027
Chd2chromodomain helicase DNA binding protein 20.026
Thoc2THO complex 20.026
Kdm5alysine (K)-specific demethylase 5A0.025
Rapgef6Rap guanine nucleotide exchange factor (GEF) 60.024
Sfswapsplicing factor, suppressor of white-apricot homolog (Drosophila)0.023
Bbxbobby sox homolog (Drosophila)0.022
Mpp5membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)0.021
Rlfrearranged L-myc fusion sequence0.020
Bod1lbiorientation of chromosomes in cell division 1-like0.020
Jarid2jumonji, AT rich interactive domain 20.019
Tet2tet oncogene family member 20.017
Brd4bromodomain containing 40.017
Fam48afamily with sequence similarity 48, member A0.017
Lats1large tumor suppressor0.016
Scaf4SR-related CTD-associated factor 40.016
Vhlvon Hippel-Lindau tumor suppressor0.016
Sp4trans-acting transcription factor 40.015
Git2G protein-coupled receptor kinase-interactor 20.015
Ddx6DEAD (Asp-Glu-Ala-Asp) box polypeptide 60.015
Suz12suppressor of zeste 12 homolog (Drosophila)0.015
Smc1astructural maintenance of chromosomes 1A0.015
BC005561cDNA sequence BC0055610.015
Itsn2intersectin 20.015
Rev3lREV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)0.015
Fam193afamily with sequence similarity 193, member A0.015
Nfat5nuclear factor of activated T-cells 50.015
Ppp6r3protein phosphatase 6, regulatory subunit 30.015
Pogzpogo transposable element with ZNF domain0.014
Mll5myeloid/lymphoid or mixed-lineage leukemia 50.014
NipblNipped-B homolog (Drosophila)0.014
Ino80dINO80 complex subunit D0.014
Mdm4transformed mouse 3T3 cell double minute 40.014
1700081L11RikRIKEN cDNA 1700081L11 gene0.014
Dtldenticleless homolog (Drosophila)0.013
Ckap5cytoskeleton associated protein 50.013
Rb1retinoblastoma 10.013
Akap13A kinase (PRKA) anchor protein 130.013
Smg1SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)0.013
Sf1splicing factor 10.013
MgaMAX gene associated0.013
Hnrnpdheterogeneous nuclear ribonucleoprotein D0.013
Smad5MAD homolog 5 (Drosophila)0.013
Ncoa2nuclear receptor coactivator 20.013
Nfyanuclear transcription factor-Y alpha0.012
Gsk3bglycogen synthase kinase 3 beta0.012
Pds5aPDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)0.012
Bptfbromodomain PHD finger transcription factor0.012
Rfx7regulatory factor X, 70.012
A230046K03RikRIKEN cDNA A230046K03 gene0.012
Brd3bromodomain containing 30.011
Klhl28kelch-like 28 (Drosophila)0.011
CblCasitas B-lineage lymphoma0.011
Dnmt3aDNA methyltransferase 3A0.011
Ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.011
Atxn7ataxin 70.011
Hdgfhepatoma-derived growth factor0.011
Kdm5blysine (K)-specific demethylase 5B0.011
Pknox1Pbx/knotted 1 homeobox0.011
Arid1aAT rich interactive domain 1A (SWI-like)0.011
Phf21aPHD finger protein 21A0.011
Cbx5chromobox homolog 5 (Drosophila HP1a)0.011
Cep110centrosomal protein 1100.010
Polr2apolymerase (RNA) II (DNA directed) polypeptide A0.010
Mphosph9M-phase phosphoprotein 90.010
XiapX-linked inhibitor of apoptosis0.010
Utrnutrophin0.010
Lime1Lck interacting transmembrane adaptor 10.010
Vezf1vascular endothelial zinc finger 10.010
Sbno1sno, strawberry notch homolog 1 (Drosophila)0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism