The network for 'dsrna fragmentation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

dsrna fragmentation

Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function.

NameDescriptionProbabilityFunc Analog Organism
pashapartner of drosha0.986
droshaCG8730 gene product from transcript CG8730-RA0.809
AGO1Argonaute-10.128
spn-Espindle E0.096
Su(var)2-HP2CG12864 gene product from transcript CG12864-RB0.041
CTCFCG8591 gene product from transcript CG8591-RA0.038
piwiCG6122 gene product from transcript CG6122-RA0.028
aubaubergine0.028
Ge-1CG6181 gene product from transcript CG6181-RA0.027
ird5immune response deficient 50.027
tho2CG31671 gene product from transcript CG31671-RA0.026
Rbsn-5Rabenosyn-50.026
dltdiscs lost0.026
vasvasa0.025
bambag of marbles0.024
PcPolycomb0.024
Tango6Transport and Golgi organization 60.022
larkCG8597 gene product from transcript CG8597-RD0.021
stetstem cell tumor0.020
Su(var)3-3Suppressor of variegation 3-30.019
zpgzero population growth0.018
krimpkrimper0.017
CG10107CG10107 gene product from transcript CG10107-RA0.016
CG8443CG8443 gene product from transcript CG8443-RA0.016
RbfRetinoblastoma-family protein0.016
maelmaelstrom0.015
MtorMegator0.014
Tsc1CG6147 gene product from transcript CG6147-RA0.014
CG32185CG32185 gene product from transcript CG32185-RA0.013
tatltat-like0.013
magomago nashi0.013
SRPKCG8174 gene product from transcript CG8174-RA0.012
nctnicastrin0.012
Prosbeta1Proteasome beta1 subunit0.012
nudECG8104 gene product from transcript CG8104-RB0.011
Hrb98DEHeterogeneous nuclear ribonucleoprotein at 98DE0.011
chinmoChronologically inappropriate morphogenesis0.011
pgant3polypeptide GalNAc transferase 30.011
Nup160Nucleoporin 1600.011
Dcr-1Dicer-10.011
Vps25Vacuolar protein sorting 250.010
Cul-4Cullin-40.010
PargPoly(ADP-ribose) glycohydrolase0.010
CG4973CG4973 gene product from transcript CG4973-RA0.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
ulp-1Protein ULP-10.086
drh-1Protein DRH-10.048
prg-2Protein PRG-20.040
rfp-1Protein RFP-10.034
mus-101Protein MUS-1010.033
F31C3.3Protein F31C3.30.026
sacy-1Protein SACY-10.025
K02B12.5Protein K02B12.50.025
npp-12Protein NPP-120.023
gld-3Protein GLD-30.021
brc-1Protein BRC-10.021
mcm-2Protein MCM-20.021
Y37B11A.2Protein Y37B11A.20.020
lin-66Protein LIN-660.020
T05E8.3Protein T05E8.30.020
nkcc-1Protein NKCC-10.020
let-502Protein LET-5020.020
cgh-1Protein CGH-10.018
drh-3Protein DRH-30.018
ocrl-1Protein OCRL-10.018
F25H5.5Protein F25H5.50.018
CELE_Y57A10A.13Protein Y57A10A.130.018
sax-3Protein SAX-30.017
daf-15Protein DAF-150.016
ran-2Protein RAN-20.016
tag-232Protein TAG-2320.016
fli-1Protein FLI-10.015
hmp-1Protein HMP-10.015
ztf-4Protein ZTF-40.015
ztf-15Protein ZTF-150.015
CELE_C04E6.11Protein C04E6.110.014
C18D11.3Protein C18D11.30.014
Y76G2A.1Protein Y76G2A.10.013
CELE_T26A8.1Protein T26A8.10.013
rbr-2Protein RBR-20.012
klp-10Protein KLP-100.012
imb-2Protein IMB-20.012
CELE_W05H9.4Protein W05H9.40.012
ntp-1Protein NTP-10.012
C13B4.1Protein C13B4.10.012
CELE_T07C12.12Protein T07C12.120.012
mbtr-1Protein MBTR-10.012
spr-1Protein SPR-10.012
Y50D4A.4Protein Y50D4A.40.011
K06A5.1Protein K06A5.10.011
Y34D9A.3Protein Y34D9A.30.011
apc-2Protein APC-20.011
T22C1.5Protein T22C1.50.011
F13H8.2Protein F13H8.20.011
M02B1.3Protein M02B1.30.011
npp-22Protein NPP-220.011
CELE_Y57G11C.9Protein Y57G11C.90.011
lars-2Protein LARS-20.011
swsn-7Protein SWSN-70.011
lin-36Protein LIN-360.010
C30G12.6Protein C30G12.60.010
sut-2Protein SUT-20.010
ptc-1Protein PTC-10.010
pqn-85Protein PQN-850.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
nanos3nanos homolog 30.318
khdrbs1aKH domain containing, RNA binding, signal transduction associated 1a0.280
vasavasa homolog0.142
dazldaz-like gene0.116
e2f5E2F transcription factor 50.085
birc5bbaculoviral IAP repeat-containing 5B0.044
srsf2serine/arginine-rich splicing factor 20.043
tbpl2TATA box binding protein like 20.041
eif2c4eukaryotic translation initiation factor 2C, 40.039
srsf11serine/arginine-rich splicing factor 110.035
sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.035
hnrnpmheterogeneous nuclear ribonucleoprotein M0.034
hnrnpa0heterogeneous nuclear ribonucleoprotein A00.034
hnrnpkheterogeneous nuclear ribonucleoprotein K0.033
ewsr1bEwing sarcoma breakpoint region 1b0.030
LOC561889granulito0.028
tardbpTAR DNA binding protein0.027
hnrnpa0lheterogeneous nuclear ribonucleoprotein A0, like0.027
zc3h13zinc finger CCCH-type containing 130.024
lppr3blipid phosphate phosphatase-related protein type 3b0.023
pou5f1POU domain, class 5, transcription factor 10.022
cyp19a1bcytochrome P450, family 19, subfamily A, polypeptide 1b0.022
sf1splicing factor 10.021
tardbplTAR DNA binding protein, like0.021
rtf1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.020
hnrnpl2heterogeneous nuclear ribonucleoprotein L20.020
sfrs3bsplicing factor, arginine/serine-rich 3b0.020
sf3a1splicing factor 3a, subunit 10.018
ctr9Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.018
med4mediator complex subunit 40.018
prpf40aPRP40 pre-mRNA processing factor 40 homolog A (yeast)0.017
prmt1protein arginine methyltransferase 10.017
setbSET translocation (myeloid leukemia-associated) B0.017
trim71tripartite motif-containing 710.017
LOC402838hypothetical protein LOC4028380.017
syncriplsynaptotagmin binding, cytoplasmic RNA interacting protein, like0.016
gtf2h2general transcription factor IIH, polypeptide 20.016
senp3aSUMO1/sentrin/SMT3 specific peptidase 3a0.016
ap1g1adaptor-related protein complex 1, gamma 1 subunit0.016
bonbonnie and clyde0.016
ilf3binterleukin enhancer binding factor 3b0.015
nclnucleolin0.015
LOC570775protein argonaute-1-like0.014
si:ch211-59d15.5si:ch211-59d15.50.014
cnot1CCR4-NOT transcription complex, subunit 10.014
xrn25'-3' exoribonuclease 20.014
rspo1R-spondin homolog (Xenopus laevis)0.013
ef1aelongation factor 1-alpha0.013
igf3insulin-like growth factor 30.013
cyp11a1cytochrome P450, subfamily XIA, polypeptide 10.013
lgals2blectin, galactoside-binding, soluble, 2b0.013
pl10pl100.013
atp2b1aATPase, Ca++ transporting, plasma membrane 1a0.012
smarce1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.012
ext1aexostoses (multiple) 1a0.012
bucbucky ball0.012
itfg2integrin alpha FG-GAP repeat containing 20.012
hnrprheterogeneous nuclear ribonucleoprotein R0.012
cfl2lcofilin 2, like0.012
dnddead end0.012
ilf3ainterleukin enhancer binding factor 3a0.012
hnrnph1lheterogeneous nuclear ribonucleoprotein H1, like0.012
ppm1dprotein phosphatase 1D magnesium-dependent, delta isoform0.012
eif4enif1eukaryotic translation initiation factor 4E nuclear import factor 10.012
cdk7cyclin-dependent kinase 70.012
kdm1alysine (K)-specific demethylase 1a0.012
zgc:64105zgc:641050.012
ints3integrator complex subunit 30.012
prpf8pre-mRNA processing factor 80.011
arid4aAT rich interactive domain 4A (RBP1-like)0.011
luc7lLUC7-like (S. cerevisiae)0.011
med19bmediator complex subunit 19b0.011
zgc:85716zgc:857160.011
map3k4mitogen activated protein kinase kinase kinase 40.011
bmp15bone morphogenetic protein 150.011
safbscaffold attachment factor B0.011
LOC100003640cyclin-dependent kinase 2-interacting protein-like0.011
gmpsguanine monphosphate synthetase0.011
im:6907928im:69079280.010
eif3s10eukaryotic translation initiation factor 3, subunit 10 (theta)0.010
ubr5ubiquitin protein ligase E3 component n-recognin 50.010
snrnp70small nuclear ribonucleoprotein 70 (U1)0.010
tfip11tuftelin interacting protein 110.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EIF2C2eukaryotic translation initiation factor 2C, 21.000
EIF2C1eukaryotic translation initiation factor 2C, 11.000
EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 20.999
PRKRAprotein kinase, interferon-inducible double stranded RNA dependent activator0.991
DICER1dicer 1, ribonuclease type III0.983
EIF2C3eukaryotic translation initiation factor 2C, 30.922
PABPC1poly(A) binding protein, cytoplasmic 10.541
EIF2C4eukaryotic translation initiation factor 2C, 40.465
DGCR8DiGeorge syndrome critical region gene 80.437
C17orf85chromosome 17 open reading frame 850.282
CYLDcylindromatosis (turban tumor syndrome)0.238
TARBP2TAR (HIV-1) RNA binding protein 20.219
TNRC6Btrinucleotide repeat containing 6B0.188
NCBP1nuclear cap binding protein subunit 1, 80kDa0.144
DROSHAdrosha, ribonuclease type III0.130
TNRC6Atrinucleotide repeat containing 6A0.115
STAT1signal transducer and activator of transcription 1, 91kDa0.088
IPO8importin 80.065
TRIM25tripartite motif containing 250.062
DDX20DEAD (Asp-Glu-Ala-Asp) box polypeptide 200.050
PARP12poly (ADP-ribose) polymerase family, member 120.047
MFAP1microfibrillar-associated protein 10.046
TRIM71tripartite motif containing 710.040
FUSfused in sarcoma0.028
MYSM1Myb-like, SWIRM and MPN domains 10.027
DTX3Ldeltex 3-like (Drosophila)0.026
ZC3HAV1zinc finger CCCH-type, antiviral 10.024
WWP2WW domain containing E3 ubiquitin protein ligase 20.023
SAMD9sterile alpha motif domain containing 90.023
PARP9poly (ADP-ribose) polymerase family, member 90.023
PARNpoly(A)-specific ribonuclease (deadenylation nuclease)0.020
XPO1exportin 1 (CRM1 homolog, yeast)0.020
ZMAT3zinc finger, matrin-type 30.019
ZFP28zinc finger protein 28 homolog (mouse)0.017
RBM39RNA binding motif protein 390.017
USP18ubiquitin specific peptidase 180.015
SF3A2splicing factor 3a, subunit 2, 66kDa0.014
FTSJD2FtsJ methyltransferase domain containing 20.013
PARP14poly (ADP-ribose) polymerase family, member 140.012
PIWIL1piwi-like 1 (Drosophila)0.011
FRA10AC1fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 10.011
MOV10Mov10, Moloney leukemia virus 10, homolog (mouse)0.011
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.011
PIN1peptidylprolyl cis/trans isomerase, NIMA-interacting 10.010
DDX39BDEAD (Asp-Glu-Ala-Asp) box polypeptide 39B0.010
NCBP2nuclear cap binding protein subunit 2, 20kDa0.010
HERC5hect domain and RLD 50.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ddx60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.829
Rtp4receptor transporter protein 40.069
Usp18ubiquitin specific peptidase 180.059
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.050
Safbscaffold attachment factor B0.048
Stat1signal transducer and activator of transcription 10.036
Irf7interferon regulatory factor 70.031
Hsf2heat shock factor 20.029
Droshadrosha, ribonuclease type III0.022
Atrataxia telangiectasia and Rad3 related0.020
Ddx6DEAD (Asp-Glu-Ala-Asp) box polypeptide 60.019
Trim25tripartite motif-containing 250.018
Trim32tripartite motif-containing 320.017
U2af2U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 20.016
Lin28alin-28 homolog A (C. elegans)0.015
Ifit1interferon-induced protein with tetratricopeptide repeats 10.013
Irgm1immunity-related GTPase family M member 10.012
Trim21tripartite motif-containing 210.011
Lin28blin-28 homolog B (C. elegans)0.011
Irf9interferon regulatory factor 90.011
Oasl22'-5' oligoadenylate synthetase-like 20.010
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Wdfy1WD repeat and FYVE domain containing 10.034
Prpf38aPRP38 pre-mRNA processing factor 38 (yeast) domain containing A0.018
Synrgsynergin, gamma0.016
Rab5bRAB5B, member RAS oncogene family0.016
Lsm5LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.015
Pnrc2proline-rich nuclear receptor coactivator 20.014
Nfixnuclear factor I/X (CCAAT-binding transcription factor)0.012
Clcn7chloride channel 70.012
Rcn2reticulocalbin 2, EF-hand calcium binding domain0.012
Sbf1SET binding factor 10.011
RGD1306404similar to mKIAA1402 protein0.011
Rab14RAB14, member RAS oncogene family0.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism