The network for 'substrate adhesion dependent cell spreading' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

substrate adhesion dependent cell spreading

The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.

NameDescriptionProbabilityFunc Analog Organism
LamCLamin C0.632
lqfliquid facets0.213
Cg25CCollagen type IV0.208
Rac2CG8556 gene product from transcript CG8556-RA0.153
LanALaminin A0.114
mewmultiple edematous wings0.084
rheaCG6831 gene product from transcript CG6831-RA0.081
Arp66BActin-related protein 66B0.080
PvrPDGF- and VEGF-receptor related0.080
Vrp1Verprolin 10.077
TER94CG2331 gene product from transcript CG2331-RA0.061
Rho1CG8416 gene product from transcript CG8416-RB0.058
rtrotated abdomen0.054
TimpTissue inhibitor of metalloproteases0.049
Mpk2CG5475 gene product from transcript CG5475-RB0.046
Cdc42CG12530 gene product from transcript CG12530-RA0.041
CG31352CG31352 gene product from transcript CG31352-RA0.041
shotshort stop0.039
LanB2Laminin B20.036
DuoxDual oxidase0.035
stumpsCG31317 gene product from transcript CG31317-RC0.034
jimCG11352 gene product from transcript CG11352-RB0.032
Fer1HCHFerritin 1 heavy chain homologue0.032
unc-13CG2999 gene product from transcript CG2999-RA0.031
drongoCG3365 gene product from transcript CG3365-RH0.030
Fkbp13CG9847 gene product from transcript CG9847-RC0.029
Rab5Rab-protein 50.029
blowblown fuse0.028
sharkSrc homology 2, ankyrin repeat, tyrosine kinase0.028
NFATNFAT homolog0.028
solsmall optic lobes0.027
Xrp1CG17836 gene product from transcript CG17836-RB0.027
CG1600CG1600 gene product from transcript CG1600-RA0.026
Pk61CProtein kinase 61C0.026
NUCB1CG32190 gene product from transcript CG32190-RA0.025
Rab7Rab-protein 70.025
l(3)L1231lethal (3) L12310.024
Nc73EFNeural conserved at 73EF0.024
CG10627CG10627 gene product from transcript CG10627-RA0.024
p130CASCG1212 gene product from transcript CG1212-RA0.024
CG14625CG14625 gene product from transcript CG14625-RB0.023
alpha-Specalpha Spectrin0.023
cindrCIN85 and CD2AP orthologue0.022
PgkPhosphoglycerate kinase0.022
CG8121CG8121 gene product from transcript CG8121-RA0.022
Smg1CG32743 gene product from transcript CG32743-RA0.022
Rab11Rab-protein 110.021
howheld out wings0.021
GluRIIAGlutamate receptor IIA0.021
DlicDynein light intermediate chain0.021
Rac1CG2248 gene product from transcript CG2248-RA0.021
l(2)05510lethal (2) 055100.020
CG9990CG9990 gene product from transcript CG9990-RA0.020
Reg-5Rhythmically expressed gene 50.020
sar1CG7073 gene product from transcript CG7073-RB0.020
mbcmyoblast city0.020
RpS16Ribosomal protein S160.020
CG6038CG6038 gene product from transcript CG6038-RA0.020
Cnx99ACalnexin 99A0.019
CG8449CG8449 gene product from transcript CG8449-RA0.019
CG30159CG30159 gene product from transcript CG30159-RC0.019
CG16947CG16947 gene product from transcript CG16947-RA0.019
CG8709CG8709 gene product from transcript CG8709-RK0.018
RpLP2Ribosomal protein LP20.018
CG5798CG5798 gene product from transcript CG5798-RA0.018
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)1.000
FHL2four and a half LIM domains 20.998
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.985
PDIA3protein disulfide isomerase family A, member 30.982
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.964
FN1fibronectin 10.961
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.941
LAMC1laminin, gamma 1 (formerly LAMB2)0.928
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.864
S100A9S100 calcium binding protein A90.810
PTK2PTK2 protein tyrosine kinase 20.792
FLNAfilamin A, alpha0.785
ILKintegrin-linked kinase0.783
ITGA3integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)0.710
LGALS1lectin, galactoside-binding, soluble, 10.612
S100A6S100 calcium binding protein A60.590
S100A8S100 calcium binding protein A80.572
EPHA2EPH receptor A20.497
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.449
BCAR1breast cancer anti-estrogen resistance 10.432
RAC2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.414
PSEN2presenilin 2 (Alzheimer disease 4)0.410
ITGAVintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)0.366
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.346
FYNFYN oncogene related to SRC, FGR, YES0.331
TLN1talin 10.278
CLASP1cytoplasmic linker associated protein 10.275
FLNBfilamin B, beta0.270
S100A4S100 calcium binding protein A40.270
LAMB1laminin, beta 10.238
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.221
COL7A1collagen, type VII, alpha 10.216
LIMS1LIM and senescent cell antigen-like domains 10.209
GAS6growth arrest-specific 60.196
PARVAparvin, alpha0.193
S100A2S100 calcium binding protein A20.192
ANGPT2angiopoietin 20.181
CALD1caldesmon 10.168
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.159
ANXA2annexin A20.152
LMNAlamin A/C0.125
THBS1thrombospondin 10.120
APOC1apolipoprotein C-I0.110
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.108
ITGA6integrin, alpha 60.105
VCAM1vascular cell adhesion molecule 10.104
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.098
MDM4Mdm4 p53 binding protein homolog (mouse)0.094
NCK2NCK adaptor protein 20.090
ITGA2integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)0.090
LTBP2latent transforming growth factor beta binding protein 20.085
ANGPT1angiopoietin 10.078
GRB7growth factor receptor-bound protein 70.075
ANXA1annexin A10.070
TCF4transcription factor 40.068
LAMB3laminin, beta 30.066
STX4syntaxin 40.066
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.066
EPHA7EPH receptor A70.065
LAMC2laminin, gamma 20.065
ZNF746zinc finger protein 7460.062
CD63CD63 molecule0.058
AHNAKAHNAK nucleoprotein0.057
TENC1tensin like C1 domain containing phosphatase (tensin 2)0.056
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.055
TRIP6thyroid hormone receptor interactor 60.054
RHOCras homolog gene family, member C0.051
ITGA4integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)0.050
ANXA5annexin A50.050
CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b0.050
EPHA3EPH receptor A30.048
RRASrelated RAS viral (r-ras) oncogene homolog0.046
APPamyloid beta (A4) precursor protein0.045
EPS8epidermal growth factor receptor pathway substrate 80.045
ITGB4integrin, beta 40.045
ITGA7integrin, alpha 70.045
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.043
KRT17keratin 170.043
SORBS3sorbin and SH3 domain containing 30.042
TGFBR1transforming growth factor, beta receptor 10.042
TGFB2transforming growth factor, beta 20.041
CLDN1claudin 10.041
COL17A1collagen, type XVII, alpha 10.040
CTGFconnective tissue growth factor0.040
ITGB5integrin, beta 50.039
FAF1Fas (TNFRSF6) associated factor 10.038
PLP2proteolipid protein 2 (colonic epithelium-enriched)0.038
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Itgb1integrin beta 1 (fibronectin receptor beta)0.989
Ptk2PTK2 protein tyrosine kinase 20.976
AxlAXL receptor tyrosine kinase0.943
Parvaparvin, alpha0.900
Ilkintegrin linked kinase0.832
Gab1growth factor receptor bound protein 2-associated protein 10.793
Lamc1laminin, gamma 10.776
WasWiskott-Aldrich syndrome homolog (human)0.723
Nid1nidogen 10.597
Dok1docking protein 10.552
Inpp5dinositol polyphosphate-5-phosphatase D0.453
Gopcgolgi associated PDZ and coiled-coil motif containing0.341
Psen1presenilin 10.319
Itga3integrin alpha 30.294
Ctnnb1catenin (cadherin associated protein), beta 10.293
Notch2Notch gene homolog 2 (Drosophila)0.268
Dlg4discs, large homolog 4 (Drosophila)0.265
Wnt5awingless-related MMTV integration site 5A0.253
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.216
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.209
Ikzf1IKAROS family zinc finger 10.208
Lama5laminin, alpha 50.207
Rac2RAS-related C3 botulinum substrate 20.203
Cd151CD151 antigen0.191
Tyro3TYRO3 protein tyrosine kinase 30.190
Hif1ahypoxia inducible factor 1, alpha subunit0.183
Vegfavascular endothelial growth factor A0.180
Epb4.1l2erythrocyte protein band 4.1-like 20.175
Ephb2Eph receptor B20.174
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.170
Efnb2ephrin B20.170
Hcls1hematopoietic cell specific Lyn substrate 10.162
Bcar1breast cancer anti-estrogen resistance 10.162
Lims1LIM and senescent cell antigen-like domains 10.162
Grb2growth factor receptor bound protein 20.161
Appamyloid beta (A4) precursor protein0.155
CblCasitas B-lineage lymphoma0.153
Fzd8frizzled homolog 8 (Drosophila)0.147
Wwtr1WW domain containing transcription regulator 10.146
Actn4actinin alpha 40.137
Wnt7bwingless-related MMTV integration site 7B0.133
Fn1fibronectin 10.133
Cpdcarboxypeptidase D0.127
Gpc3glypican 30.127
Capn2calpain 20.122
Arhgap9Rho GTPase activating protein 90.121
SrcRous sarcoma oncogene0.117
S100a11S100 calcium binding protein A11 (calgizzarin)0.116
Col4a2collagen, type IV, alpha 20.116
Pdgfbplatelet derived growth factor, B polypeptide0.115
Retret proto-oncogene0.115
Cald1caldesmon 10.114
Mertkc-mer proto-oncogene tyrosine kinase0.110
Cd19CD19 antigen0.107
Plcg2phospholipase C, gamma 20.107
FynFyn proto-oncogene0.104
Map4k1mitogen-activated protein kinase kinase kinase kinase 10.101
Magi1membrane associated guanylate kinase, WW and PDZ domain containing 10.101
Cnn2calponin 20.101
Ptpreprotein tyrosine phosphatase, receptor type, E0.100
Ednrbendothelin receptor type B0.099
Cd22CD22 antigen0.097
Fermt2fermitin family homolog 2 (Drosophila)0.097
Abcd1ATP-binding cassette, sub-family D (ALD), member 10.097
S1pr4sphingosine-1-phosphate receptor 40.094
Prkcdprotein kinase C, delta0.093
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.089
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.089
Crklv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.087
Plod3procollagen-lysine, 2-oxoglutarate 5-dioxygenase 30.086
S1pr3sphingosine-1-phosphate receptor 30.085
Igfbp2insulin-like growth factor binding protein 20.085
Tead2TEA domain family member 20.084
Dlg1discs, large homolog 1 (Drosophila)0.081
SpibSpi-B transcription factor (Spi-1/PU.1 related)0.081
Lama4laminin, alpha 40.079
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.078
Rac1RAS-related C3 botulinum substrate 10.078
F2rcoagulation factor II (thrombin) receptor0.077
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.077
Rbms1RNA binding motif, single stranded interacting protein 10.077
Emp2epithelial membrane protein 20.074
Grb7growth factor receptor bound protein 70.074
Rnd3Rho family GTPase 30.074
Ddr2discoidin domain receptor family, member 20.071
ArhgdiaRho GDP dissociation inhibitor (GDI) alpha0.070
Snap25synaptosomal-associated protein 250.070
Stx1asyntaxin 1A (brain)0.069
Myo1fmyosin IF0.069
Mfap2microfibrillar-associated protein 20.068
Git1G protein-coupled receptor kinase-interactor 10.068
Prkciprotein kinase C, iota0.068
Hs3st3a1heparan sulfate (glucosamine) 3-O-sulfotransferase 3A10.067
Fstl1follistatin-like 10.067
Cd37CD37 antigen0.066
Cd97CD97 antigen0.064
Lamb1laminin B10.062
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism