The network for 'centriole replication' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

centriole replication

The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type.

NameDescriptionProbabilityFunc Analog Organism
Cep135CG17081 gene product from transcript CG17081-RB0.961
ana3anastral spindle 30.905
Poc1Proteome of centrioles 10.853
CG5690CG5690 gene product from transcript CG5690-RA0.809
sas-6spindle assembly abnormal 60.749
Cp110CG14617 gene product from transcript CG14617-RB0.673
ana2anastral spindle 20.648
Sas-4CG10061 gene product from transcript CG10061-RA0.588
marsCG17064 gene product from transcript CG17064-RB0.355
l(1)dd4lethal (1) discs degenerate 40.309
aspabnormal spindle0.228
spd-2spindle defective 20.210
SAKSak kinase0.210
rodrough deal0.176
lkb1CG9374 gene product from transcript CG9374-RJ0.169
Cp190Centrosomal protein 190kD0.137
Klp61FKinesin-like protein at 61F0.108
sinaseven in absentia0.102
Rae1CG9862 gene product from transcript CG9862-RA0.092
BubR1Bub1-related kinase0.088
CG6954CG6954 gene product from transcript CG6954-RB0.082
Hsp83Heat shock protein 830.079
Dlc90FDynein light chain 90F0.070
MybMyb oncogene-like0.064
Klp10ACG1453 gene product from transcript CG1453-RA0.058
Kap-alpha3karyopherin alpha30.056
MioMlx interactor0.052
Klp67AKinesin-like protein at 67A0.048
TrfTBP-related factor0.046
hydhyperplastic discs0.046
Pp1-87BProtein phosphatase 1 at 87B0.045
Nup44ANucleoporin 44A0.043
cp309CG33957 gene product from transcript CG33957-RB0.043
ctpcut up0.037
Trxr-1Thioredoxin reductase-10.036
chbchromosome bows0.035
mei-S332meiotic from via Salaria 3320.032
ncdnon-claret disjunctional0.031
PPP4R2rProtein phosphatase 4 regulatory subunit 2-related protein0.030
tacctransforming acidic coiled-coil protein0.030
Sgt1CG9617 gene product from transcript CG9617-RA0.028
Klp3AKinesin-like protein at 3A0.023
CspCysteine string protein0.023
CkIalphaCasein kinase Ialpha0.023
Cks30ACyclin-dependent kinase subunit 30A0.022
Fs(2)KetFemale sterile (2) Ketel0.022
Df31Decondensation factor 310.020
MED31Mediator complex subunit 310.020
Rab2Rab-protein 20.019
CG5525CG5525 gene product from transcript CG5525-RA0.019
CycB3Cyclin B30.019
Traf-likeTNF-receptor-associated factor-like0.018
Taf2TBP-associated factor 20.018
nmdno mitochondrial derivative0.018
larpLa related protein0.018
ChcClathrin heavy chain0.017
Karybeta3Karyopherin beta 30.017
dgt1dim gamma-tubulin 10.016
poloCG12306 gene product from transcript CG12306-RA0.016
alpha-AdaptinCG4260 gene product from transcript CG4260-RA0.016
Mcm2Minichromosome maintenance 20.016
Vap-33-1CG5014 gene product from transcript CG5014-RB0.015
Nsf2NEM-sensitive fusion protein 20.015
CG7338CG7338 gene product from transcript CG7338-RA0.015
nmdyn-D7CG8362 gene product from transcript CG8362-RA0.015
CG7795CG7795 gene product from transcript CG7795-RD0.014
Taf4TBP-associated factor 40.014
l(1)G0148lethal (1) G01480.014
eIF4Geukaryotic translation initiation factor 4G0.014
CG14712CG14712 gene product from transcript CG14712-RA0.014
tilBtouch insensitive larva B0.014
CG10418CG10418 gene product from transcript CG10418-RA0.013
mei-217CG33935 gene product from transcript CG33935-RC0.013
ToporsTopoisomerase I-interacting protein0.013
CG10638CG10638 gene product from transcript CG10638-RA0.013
poepurity of essence0.013
InvadolysinCG3953 gene product from transcript CG3953-RA0.013
CG1868CG1868 gene product from transcript CG1868-RB0.013
easeasily shocked0.013
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CENPJcentromere protein J0.905
SASS6spindle assembly 6 homolog (C. elegans)0.424
CEP135centrosomal protein 135kDa0.402
NEURL4neuralized homolog 4 (Drosophila)0.292
STILSCL/TAL1 interrupting locus0.284
BTRCbeta-transducin repeat containing0.224
LIN9lin-9 homolog (C. elegans)0.193
WEE1WEE1 homolog (S. pombe)0.124
RB1retinoblastoma 10.120
CDC25Acell division cycle 25 homolog A (S. pombe)0.109
LIN54lin-54 homolog (C. elegans)0.100
TCP1t-complex 10.091
SKA1spindle and kinetochore associated complex subunit 10.063
FBXW11F-box and WD repeat domain containing 110.054
CCT8chaperonin containing TCP1, subunit 8 (theta)0.050
SKA3spindle and kinetochore associated complex subunit 30.047
CUL1cullin 10.045
CCNE1cyclin E10.034
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.034
STRN3striatin, calmodulin binding protein 30.034
NLKnemo-like kinase0.034
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.030
STARD9StAR-related lipid transfer (START) domain containing 90.029
PRNPprion protein0.027
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma0.026
CEP97centrosomal protein 97kDa0.023
SKP1S-phase kinase-associated protein 10.021
CHEK2CHK2 checkpoint homolog (S. pombe)0.019
PPME1protein phosphatase methylesterase 10.017
PPP2R1Bprotein phosphatase 2, regulatory subunit A, beta0.016
RBL1retinoblastoma-like 1 (p107)0.014
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.014
YAP1Yes-associated protein 10.013
CHEK1CHK1 checkpoint homolog (S. pombe)0.012
PDE6Dphosphodiesterase 6D, cGMP-specific, rod, delta0.012
SERTAD4SERTA domain containing 40.012
XRCC1X-ray repair complementing defective repair in Chinese hamster cells 10.012
CDK2cyclin-dependent kinase 20.011
ORC1origin recognition complex, subunit 10.011
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.011
CCNB2cyclin B20.011
MDM2Mdm2 p53 binding protein homolog (mouse)0.010
CDC25Ccell division cycle 25 homolog C (S. pombe)0.010
TNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase0.010
GTSE1G-2 and S-phase expressed 10.010
CDT1chromatin licensing and DNA replication factor 10.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Cdc25bcell division cycle 25 homolog B (S. pombe)0.023
Sgol1shugoshin-like 1 (S. pombe)0.016
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.014
Rad51ap1RAD51 associated protein 10.012
Igbp1immunoglobulin (CD79A) binding protein 10.010
Skp1aS-phase kinase-associated protein 1A0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism