The network for 'glial cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

glial cell proliferation

The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.

NameDescriptionProbabilityFunc Analog Organism
E(spl)Enhancer of split0.399
HLHmgammaE(spl) region transcript mgamma0.172
malphaE(spl) region transcript malpha0.156
HLHm7E(spl) region transcript m70.132
ppanpeter pan0.103
jebjelly belly0.080
CG4554CG4554 gene product from transcript CG4554-RA0.079
CG8064CG8064 gene product from transcript CG8064-RA0.074
cicubitus interruptus0.063
rapretina aberrant in pattern0.062
CG7246CG7246 gene product from transcript CG7246-RA0.061
HLHm5E(spl) region transcript m50.060
CG12499CG12499 gene product from transcript CG12499-RA0.059
HLHmdeltaE(spl) region transcript mdelta0.056
CG8326CG8326 gene product from transcript CG8326-RA0.056
emcextra macrochaetae0.054
Mat89BaMaternal transcript 89Ba0.053
HLHmbetaE(spl) region transcript mbeta0.052
Su(H)Suppressor of Hairless0.050
CG14230CG14230 gene product from transcript CG14230-RA0.040
amosabsent MD neurons and olfactory sensilla0.039
RpI135RNA polymerase I 135kD subunit0.039
HLHm3E(spl) region transcript m30.034
Sas10CG4202 gene product from transcript CG4202-RA0.033
slp1sloppy paired 10.030
CG11555CG11555 gene product from transcript CG11555-RA0.029
shotshort stop0.024
Gnf1Germ line transcription factor 10.022
Hsc70-3Heat shock protein cognate 30.022
CG6724CG6724 gene product from transcript CG6724-RA0.022
CG10630CG10630 gene product from transcript CG10630-RA0.021
NotumCG13076 gene product from transcript CG13076-RB0.021
CG8461CG8461 gene product from transcript CG8461-RA0.021
bysby S60.021
CG18273CG18273 gene product from transcript CG18273-RA0.019
SmoxSmad on X0.018
stumpsCG31317 gene product from transcript CG31317-RC0.018
Tsc1CG6147 gene product from transcript CG6147-RA0.018
ponpartner of numb0.018
Apc10Anaphase promoting complex subunit 100.017
Pi3K92ECG4141 gene product from transcript CG4141-RB0.017
Nmd3Nonsense-mediated mRNA 30.017
m4E(spl) region transcript m40.017
l(1)G0020lethal (1) G00200.017
Dhc64CDynein heavy chain 64C0.016
CG31223CG31223 gene product from transcript CG31223-RA0.016
gfzfGST-containing FLYWCH zinc-finger protein0.016
CG11660CG11660 gene product from transcript CG11660-RA0.015
Nop60BNucleolar protein at 60B0.015
aopanterior open0.015
AlkCG8250 gene product from transcript CG8250-RA0.015
NAT1CG3845 gene product from transcript CG3845-RA0.014
CG11859CG11859 gene product from transcript CG11859-RA0.014
CG7275CG7275 gene product from transcript CG7275-RA0.014
CG30007CG30007 gene product from transcript CG30007-RB0.014
NacalphaNascent polypeptide associated complex protein alpha subunit0.014
CG3735CG3735 gene product from transcript CG3735-RA0.014
S6kRPS6-p70-protein kinase0.014
Lrr47Leucine-rich repeat 470.014
DadDaughters against dpp0.014
CG12325CG12325 gene product from transcript CG12325-RA0.013
Mys45AMystery 45A0.013
Dbp73DDead box protein 73D0.013
CG10741CG10741 gene product from transcript CG10741-RB0.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
notch3notch homolog 30.800
neo1neogenin 10.330
jag1bjagged 1b0.285
epb41l5erythrocyte membrane protein band 4.1 like 50.158
ptprsaprotein tyrosine phosphatase, receptor type, s, a0.147
nf1aneurofibromin 1a0.144
ahr2aryl hydrocarbon receptor 20.135
rad21RAD21 homolog (S. pombe)0.135
cldn5aclaudin 5a0.124
copebcore promoter element binding protein0.118
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.113
appbamyloid beta (A4) precursor protein b0.103
crb2acrumbs homolog 2a0.092
nr2f1anuclear receptor subfamily 2, group F, member 1a0.092
mibmind bomb0.089
notch2notch homolog 20.088
tmem2transmembrane protein 20.086
nr2f2nuclear receptor subfamily 2, group F, member 20.083
nf1bneurofibromin 1b0.079
tshz1teashirt family zinc finger 10.078
cdoncell adhesion molecule-related/down-regulated by oncogenes0.073
actn1actinin, alpha 10.072
supt6hsuppressor of Ty 6 homolog0.071
lmx1b.1LIM homeobox transcription factor 1, beta 10.071
sox10SRY-box containing gene 100.069
mdkamidkine-related growth factor0.067
flot1bflotillin 1b0.065
gapdhsglyceraldehyde-3-phosphate dehydrogenase, spermatogenic0.063
col12a1collagen, type XII, alpha 10.061
apcadenomatosis polyposis coli0.058
il1binterleukin 1, beta and interleukin 1, beta0.057
cftrcystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)0.055
alcamaactivated leukocyte cell adhesion molecule a0.053
jag1ajagged 1a0.053
plagxpleiomorphic adenoma gene X0.050
sulf2lsulfatase 2, like0.050
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.050
tsc2tuberous sclerosis 20.050
nppanatriuretic peptide precursor A0.049
tcf12transcription factor 120.045
tcf7l1btranscription factor 7-like 1b (T-cell specific, HMG-box)0.045
LOC799612prolactin 20.044
emx2empty spiracles homeobox 20.044
auts2autism susceptibility candidate 20.043
kdrlkinase insert domain receptor like0.042
igf2binsulin-like growth factor 2b0.041
prnprs3prion protein, related sequence 30.039
sox11aSRY-box containing gene 11a0.039
pikfyvephosphoinositide kinase, FYVE finger containing0.039
nrp1aneuropilin 1a0.038
rab11fip4aRAB11 family interacting protein 4 (class II) a0.038
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.038
s1pr1sphingosine-1-phosphate receptor 10.038
plcb3phospholipase C, beta 3 (phosphatidylinositol-specific)0.037
plxna3plexin A30.037
kal1bKallmann syndrome 1b sequence0.037
mapkapk2amitogen-activated protein kinase-activated protein kinase 2a0.037
msi1musashi homolog 1 (Drosophila)0.036
rtf1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.036
crb1crumbs homolog 1 (Drosophila)0.036
mycamyelocytomatosis oncogene a0.036
tmsbthymosin, beta0.036
hnf1bbHNF1 homeobox Bb0.035
extl3exostoses (multiple)-like 30.035
LOC565254protein kinase domain-containing protein, cytoplasmic-like0.035
ctgfconnective tissue growth factor0.035
ascl1aachaete-scute complex-like 1a (Drosophila)0.035
mmp2matrix metalloproteinase 20.034
fstafollistatin a0.034
dbhdopamine beta hydroxylase0.034
ptpraprotein tyrosine phosphatase, receptor type, A0.033
insm1ainsulinoma-associated 1a0.033
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.033
chatcholine acetyltransferase0.032
robo2roundabout homolog 20.032
kif3bkinesin family member 3B0.032
gli2aGLI-Kruppel family member GLI2a0.032
vegfabvascular endothelial growth factor Ab0.031
tnfsf10ltumor necrosis factor (ligand) superfamily, member 10 like0.031
gpm6baglycoprotein M6Ba0.031
pcdh18aprotocadherin 18a0.031
mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.031
macf1microtubule-actin crosslinking factor 10.031
dao.2D-amino-acid oxidase 20.030
ptp4a1protein tyrosine phosphatase type IVA, member 10.030
hey1hairy/enhancer-of-split related with YRPW motif 10.029
hcrthypocretin (orexin) neuropeptide precursor0.029
vsx2visual system homeobox 20.029
thraathyroid hormone receptor alpha a0.029
tlk2tousled-like kinase 20.029
LOC100000934hypothetical protein LOC1000009340.029
pcdh19protocadherin 190.029
prkcqprotein kinase C, theta0.028
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
NOTCH1notch 10.234
NOTCH3notch 30.189
PAX3paired box 30.093
POU3F2POU class 3 homeobox 20.067
CD44CD44 molecule (Indian blood group)0.056
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.049
WEE1WEE1 homolog (S. pombe)0.046
NOXA1NADPH oxidase activator 10.045
AMOTL1angiomotin like 10.043
SMAD7SMAD family member 70.041
POU5F1POU class 5 homeobox 10.037
SCHIP1schwannomin interacting protein 10.034
GFI1Bgrowth factor independent 1B transcription repressor0.034
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.033
NCF1neutrophil cytosolic factor 10.032
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.031
SMAD3SMAD family member 30.028
MAPTmicrotubule-associated protein tau0.026
SMAD4SMAD family member 40.025
TRIM9tripartite motif containing 90.024
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.024
PRKCAprotein kinase C, alpha0.019
SMAD1SMAD family member 10.015
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.015
TSC22D1TSC22 domain family, member 10.014
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.012
PRKCBprotein kinase C, beta0.011
S100A4S100 calcium binding protein A40.011
TJP1tight junction protein 1 (zona occludens 1)0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Itgb1integrin beta 1 (fibronectin receptor beta)0.823
Notch1Notch gene homolog 1 (Drosophila)0.816
Hes1hairy and enhancer of split 1 (Drosophila)0.779
Nf1neurofibromatosis 10.712
Apcadenomatosis polyposis coli0.707
Fgfr2fibroblast growth factor receptor 20.544
Fgfr1fibroblast growth factor receptor 10.544
Gli3GLI-Kruppel family member GLI30.538
Ptenphosphatase and tensin homolog0.499
Chd7chromodomain helicase DNA binding protein 70.442
Sox2SRY-box containing gene 20.332
Ptpn11protein tyrosine phosphatase, non-receptor type 110.315
Dll1delta-like 1 (Drosophila)0.296
Shhsonic hedgehog0.276
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.273
Trp53transformation related protein 530.246
Bmp4bone morphogenetic protein 40.237
Yap1yes-associated protein 10.219
Pax3paired box gene 30.205
Otx2orthodenticle homolog 2 (Drosophila)0.200
Kitkit oncogene0.199
Ctnnb1catenin (cadherin associated protein), beta 10.192
Vegfavascular endothelial growth factor A0.180
Ddx60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.179
Pitx2paired-like homeodomain transcription factor 20.152
Meox2mesenchyme homeobox 20.151
Psen1presenilin 10.145
Emx1empty spiracles homolog 1 (Drosophila)0.144
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.107
Isl1ISL1 transcription factor, LIM/homeodomain0.104
Bmpr1abone morphogenetic protein receptor, type 1A0.096
Pax6paired box gene 60.091
Efnb2ephrin B20.089
Sox11SRY-box containing gene 110.084
Notch2Notch gene homolog 2 (Drosophila)0.081
Gli2GLI-Kruppel family member GLI20.079
Rb1retinoblastoma 10.076
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.067
Foxc1forkhead box C10.066
Wwtr1WW domain containing transcription regulator 10.060
Gata4GATA binding protein 40.048
Bcl2B-cell leukemia/lymphoma 20.044
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.043
Pbx1pre B-cell leukemia transcription factor 10.042
Smad4MAD homolog 4 (Drosophila)0.042
Eya1eyes absent 1 homolog (Drosophila)0.040
Tcfap2atranscription factor AP-2, alpha0.038
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.037
Neflneurofilament, light polypeptide0.035
Fgf8fibroblast growth factor 80.035
Insm1insulinoma-associated 10.035
Retret proto-oncogene0.035
Smad3MAD homolog 3 (Drosophila)0.033
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.032
Sox4SRY-box containing gene 40.031
Cdkn1bcyclin-dependent kinase inhibitor 1B0.030
Prkceprotein kinase C, epsilon0.030
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.029
Hesx1homeobox gene expressed in ES cells0.029
Gata3GATA binding protein 30.027
Pkd1polycystic kidney disease 1 homolog0.026
Foxg1forkhead box G10.026
Smosmoothened homolog (Drosophila)0.025
Notch3Notch gene homolog 3 (Drosophila)0.025
Tead1TEA domain family member 10.024
Rxraretinoid X receptor alpha0.024
Ptch1patched homolog 10.023
Lhx3LIM homeobox protein 30.023
Dll4delta-like 4 (Drosophila)0.022
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.022
Nkx2-3NK2 transcription factor related, locus 3 (Drosophila)0.021
Tgfb2transforming growth factor, beta 20.020
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.020
Ctnnd1catenin (cadherin associated protein), delta 10.020
Fgf4fibroblast growth factor 40.019
Shesrc homology 2 domain-containing transforming protein E0.019
Kdrkinase insert domain protein receptor0.018
Jag2jagged 20.018
Hand1heart and neural crest derivatives expressed transcript 10.017
Tcf15transcription factor 150.017
Shank3SH3/ankyrin domain gene 30.017
Gsk3bglycogen synthase kinase 3 beta0.016
SrcRous sarcoma oncogene0.016
Prkar1aprotein kinase, cAMP dependent regulatory, type I, alpha0.016
Vangl2vang-like 2 (van gogh, Drosophila)0.016
Alx4aristaless-like homeobox 40.016
Ramp2receptor (calcitonin) activity modifying protein 20.016
Prnpprion protein0.016
Nkx2-2NK2 transcription factor related, locus 2 (Drosophila)0.016
Bcl6bB-cell CLL/lymphoma 6, member B0.015
Rasip1Ras interacting protein 10.015
Hes5hairy and enhancer of split 5 (Drosophila)0.015
Smad2MAD homolog 2 (Drosophila)0.014
Per2period homolog 2 (Drosophila)0.014
Hhexhematopoietically expressed homeobox0.014
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Rnf4ring finger protein 40.024
Eif3ieukaryotic translation initiation factor 3, subunit I0.023
Mrpl22mitochondrial ribosomal protein L220.020
RGD1564058similar to cDNA sequence BC0564740.020
Mrpl27mitochondrial ribosomal protein L270.018
Spcs1signal peptidase complex subunit 1 homolog (S. cerevisiae)0.017
Tceb2transcription elongation factor B (SIII), polypeptide 20.017
Sparcsecreted protein, acidic, cysteine-rich (osteonectin)0.017
Rpl22ribosomal protein L220.017
Rpl18ribosomal protein L180.017
Krtcap2keratinocyte associated protein 20.016
Rpl8ribosomal protein L80.016
RGD1309710similar to RIKEN cDNA 0610038D110.015
Hnrnpa3heterogeneous nuclear ribonucleoprotein A30.014
Arf1ADP-ribosylation factor 10.014
CutacutA divalent cation tolerance homolog (E. coli)0.014
Rpl15ribosomal protein L150.014
Seltselenoprotein T0.014
LOC10036049160S ribosomal protein L13-like0.013
Sec13SEC13 homolog (S. cerevisiae)0.013
Tomm6translocase of outer mitochondrial membrane 6 homolog (yeast)0.013
Arl1ADP-ribosylation factor-like 10.013
RGD1304704similar to Hypothetical protein CGI-990.013
Arl5aADP-ribosylation factor-like 5A0.012
Ube2l3ubiquitin-conjugating enzyme E2L 30.012
Snrpd2small nuclear ribonucleoprotein D2 polypeptide0.012
Nhp2NHP2 ribonucleoprotein homolog (yeast)0.012
Mrp63mitochondrial ribosomal protein 630.012
Mrps16mitochondrial ribosomal protein S160.012
Elof1elongation factor 1 homolog (S. cerevisiae)0.012
Rpl35ribosomal protein L350.011
MypopMyb-related transcription factor, partner of profilin0.011
Wdr61WD repeat domain 610.011
Rps10ribosomal protein S100.011
Rps3ribosomal protein S30.011
LOC100188932dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 40.011
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.011
Ssr4signal sequence receptor, delta0.011
Tmem208transmembrane protein 2080.010
Rplp0ribosomal protein, large, P00.010
Uba52ubiquitin A-52 residue ribosomal protein fusion product 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism