The network for 'positive regulation of locomotion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of locomotion

Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.

NameDescriptionProbabilityFunc Analog Organism
Rac1CG2248 gene product from transcript CG2248-RA0.842
Fas2Fasciclin 20.474
LanALaminin A0.281
DscamDown syndrome cell adhesion molecule0.261
Rho1CG8416 gene product from transcript CG8416-RB0.170
elavembryonic lethal abnormal vision0.124
Cdc42CG12530 gene product from transcript CG12530-RA0.101
EgfrEpidermal growth factor receptor0.084
Pi3K92ECG4141 gene product from transcript CG4141-RB0.074
Syx1ASyntaxin 1A0.074
par-1CG8201 gene product from transcript CG8201-RA0.074
AblAbl tyrosine kinase0.069
hipkhomeodomain interacting protein kinase0.069
EcREcdysone receptor0.059
Ptp69DProtein tyrosine phosphatase 69D0.049
Vap-33-1CG5014 gene product from transcript CG5014-RB0.047
norpAno receptor potential A0.046
Pk61CProtein kinase 61C0.044
Wnt5Wnt oncogene analog 50.044
foxoforkhead box, sub-group O0.042
plexBplexin B0.041
CapsCalcium activated protein for secretion0.040
G-oalpha47AG protein oalpha 47A0.040
Akt1CG4006 gene product from transcript CG4006-RA0.039
CdsACDP diglyceride synthetase0.039
mewmultiple edematous wings0.037
trioCG18214 gene product from transcript CG18214-RA0.036
rdgBretinal degeneration B0.034
aopanterior open0.034
unc-13CG2999 gene product from transcript CG2999-RA0.032
gcmglial cells missing0.032
p130CASCG1212 gene product from transcript CG1212-RA0.029
reporeversed polarity0.029
Trxr-1Thioredoxin reductase-10.027
Mob2CG11711 gene product from transcript CG11711-RC0.027
easeasily shocked0.027
AcslAcyl-CoA synthetase long-chain0.026
CG4168CG4168 gene product from transcript CG4168-RA0.026
l(2)k16918lethal (2) k169180.024
BicDBicaudal D0.023
Rab5Rab-protein 50.022
S6kRPS6-p70-protein kinase0.021
Sema-1aCG18405 gene product from transcript CG18405-RD0.021
zfh1Zn finger homeodomain 10.020
Rac2CG8556 gene product from transcript CG8556-RA0.019
fasfaint sausage0.017
Fak56DFocal Adhesion Kinase0.017
RhoGAPp190CG32555 gene product from transcript CG32555-RB0.017
Ef2bElongation factor 2b0.016
Stat92ESignal-transducer and activator of transcription protein at 92E0.016
drkdownstream of receptor kinase0.015
ChcClathrin heavy chain0.014
Plc21CPhospholipase C at 21C0.014
Gyc76CGuanylyl cyclase at 76C0.014
eagether a go-go0.014
dallydivision abnormally delayed0.014
Rab7Rab-protein 70.013
CG31999CG31999 gene product from transcript CG31999-RA0.013
InRInsulin-like receptor0.013
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
dys-1Protein DYS-10.966
let-60Protein LET-600.958
slo-1Protein SLO-10.881
bar-1Protein BAR-10.871
epi-1Protein EPI-10.789
goa-1Protein GOA-10.738
egl-30Protein EGL-300.734
cam-1Protein CAM-10.610
dyb-1Protein DYB-10.595
lin-45Protein LIN-450.583
egl-18Protein EGL-180.573
daf-12Protein DAF-120.548
lam-2Protein LAM-20.531
plc-1Protein PLC-10.531
sem-5Protein SEM-50.510
egl-15Protein EGL-150.493
myo-3Protein MYO-30.488
unc-112Protein UNC-1120.486
acy-1Protein ACY-10.461
mel-11Protein MEL-110.444
lin-29Protein LIN-290.440
let-756Protein LET-7560.435
unc-73Protein UNC-730.421
pat-3Protein PAT-30.413
syg-1Protein SYG-10.405
dig-1Protein DIG-10.404
unc-52Protein UNC-520.403
gpb-1Protein GPB-10.381
bam-2Protein BAM-20.378
mig-6Protein MIG-60.372
cwn-1Protein CWN-10.359
rig-6Protein RIG-60.356
sma-6Protein SMA-60.355
unc-53Protein UNC-530.349
T21B6.3Protein T21B6.30.336
sur-2Protein SUR-20.334
unc-116Protein UNC-1160.309
vav-1Protein VAV-10.289
zyg-8Protein ZYG-80.282
mig-15Protein MIG-150.274
inx-1Protein INX-10.266
trim-9Protein TRIM-90.264
etr-1Protein ETR-10.256
let-19Protein LET-190.254
F52G3.1Protein F52G3.10.254
unc-68Protein UNC-680.238
plc-3Protein PLC-30.221
ina-1Protein INA-10.218
K08E3.5Protein K08E3.50.217
sax-3Protein SAX-30.217
lag-1Protein LAG-10.212
cnd-1Protein CND-10.207
spc-1Protein SPC-10.204
unc-83Protein UNC-830.197
unc-25Protein UNC-250.195
soc-2Protein SOC-20.192
F28E10.1Protein F28E10.10.191
stn-1Protein STN-10.182
pry-1Protein PRY-10.180
dyc-1Protein DYC-10.178
T16G1.9Protein T16G1.90.169
egl-27Protein EGL-270.165
emb-9Protein EMB-90.162
W08E3.2Protein W08E3.20.160
unc-70Protein UNC-700.159
lir-1Protein LIR-10.147
egl-13Protein EGL-130.146
fasn-1Protein FASN-10.142
unc-115Protein UNC-1150.141
itr-1Protein ITR-10.136
nhr-67Protein NHR-670.135
pde-4Protein PDE-40.133
mys-1Protein MYS-10.133
tag-232Protein TAG-2320.132
unc-9Protein UNC-90.129
eat-4Protein EAT-40.128
ZC247.2Protein ZC247.20.127
F54G2.1Protein F54G2.10.124
egl-5Protein EGL-50.124
pha-4Protein PHA-40.123
flh-2Protein FLH-20.118
lst-4Protein LST-40.115
vab-1Protein VAB-10.111
sel-8Protein SEL-80.109
ptb-1Protein PTB-10.109
R148.5Protein R148.50.107
CELE_C06B8.7Protein C06B8.70.106
hsp-3Protein HSP-30.103
unc-79Protein UNC-790.102
dlg-1Protein DLG-10.100
pqn-55Protein PQN-550.097
unc-6Protein UNC-60.096
calu-1Protein CALU-10.096
hlh-2Protein HLH-20.095
flt-1Protein FLT-10.094
R90.1Protein R90.10.093
unc-41Protein UNC-410.093
smp-1Protein SMP-10.091
ape-1Protein APE-10.088
R07E3.1Protein R07E3.10.088
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
kdrlkinase insert domain receptor like0.471
col14a1collagen, type XIV, alpha 10.441
pitx3paired-like homeodomain transcription factor 30.347
fras1Fraser syndrome 10.326
tll1tolloid-like 10.292
aldh1a2aldehyde dehydrogenase 1 family, member A20.280
tie1endothelium-specific receptor tyrosine kinase 10.185
bmp4bone morphogenetic protein 40.178
flt4fms-related tyrosine kinase 40.172
ascl1aachaete-scute complex-like 1a (Drosophila)0.171
apoebapolipoprotein Eb0.165
lamc1laminin, gamma 10.142
tal1T-cell acute lymphocytic leukemia 10.134
ikzf1IKAROS family zinc finger 1 (Ikaros)0.119
ptgs1prostaglandin-endoperoxide synthase 10.113
alcambactivated leukocyte cell adhesion molecule b0.107
ptprfprotein tyrosine phosphatase, receptor type, F0.101
LOC569128hypothetical protein LOC5691280.093
myf5myogenic factor 50.091
itgb1bintegrin, beta 1b0.090
efnb2aephrin B2a0.086
lcp1lymphocyte cytosolic plastin 10.085
cdh2cadherin 2, neuronal0.083
ptmaaprothymosin, alpha a0.079
mpxmyeloid-specific peroxidase0.076
efnb3bephrin B3b0.073
cmybtranscription factor cmyb0.071
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.070
tbx1T-box 10.066
lpar1lysophosphatidic acid receptor 10.062
slit3slit (Drosophila) homolog 30.061
ergv-ets erythroblastosis virus E26 oncogene like (avian)0.061
spns2spinster homolog 2 (Drosophila)0.058
lamb1alaminin, beta 1a0.052
rx3retinal homeobox gene 30.051
aplnraapelin receptor a0.051
itgb1b.2integrin, beta 1b.20.050
itgb1aintegrin, beta 1a0.049
prox1prospero-related homeobox gene 10.049
shhasonic hedgehog a0.048
jag1ajagged 1a0.048
gap43growth associated protein 430.047
gdf6agrowth differentiation factor 6a0.046
bnc2basonuclin 20.046
igf1insulin-like growth factor 10.045
sulf1sulfatase 10.044
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.044
col12a1collagen, type XII, alpha 10.043
nkx2.1aNK2 homeobox 1a0.043
postnperiostin, osteoblast specific factor0.042
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.042
trpm7transient receptor potential cation channel, subfamily M, member 70.040
igf1rbinsulin-like growth factor 1b receptor0.040
ptger2aprostaglandin E receptor 2a (subtype EP2)0.039
crabp2acellular retinoic acid binding protein 2, a0.039
nrp2bneuropilin 2b0.039
gata6GATA-binding protein 60.037
esr2bestrogen receptor 2b0.036
tp63tumor protein p630.036
bmp2abone morphogenetic protein 2a0.036
esrraestrogen-related receptor alpha0.035
runx1runt-related transcription factor 10.035
atoh7atonal homolog 70.035
atp6v1alATPase, H+ transporting, lysosomal V1 subunit A, like0.035
egr1early growth response 10.035
ptprkprotein tyrosine phosphatase, receptor type, K0.035
tbx20T-box 200.035
ptrfbpolymerase I and transcript release factor b0.034
ephb4aeph receptor B4a0.033
kitakit receptor a0.033
foxn4forkhead box N40.033
cntn2contactin 20.032
ventventral expressed homeobox0.032
col1a2collagen, type I, alpha 20.032
grhl2bgrainyhead-like 2b (Drosophila)0.031
fn1fibronectin 10.031
has2hyaluronan synthase 20.031
srfserum response factor0.031
atp1b1bATPase, Na+/K+ transporting, beta 1b polypeptide0.031
ptgesprostaglandin E synthase0.031
gpr126G protein-coupled receptor 1260.030
gata4GATA-binding protein 40.030
tnctenascin C0.030
trpv6transient receptor potential cation channel, subfamily V, member 60.029
wnt10awingless-type MMTV integration site family, member 10a0.029
lmnalamin A0.029
tie2endothelium-specific receptor tyrosine kinase 20.029
eno2enolase 20.029
lppLIM domain containing preferred translocation partner in lipoma0.029
itga3bintegrin, alpha 3b0.028
lama4laminin, alpha 40.028
cyp1acytochrome P450, family 1, subfamily A0.028
cyt1type I cytokeratin, enveloping layer0.028
frem3Fras1 related extracellular matrix 30.028
rhogbras homolog gene family, member Gb0.028
igfbp5ainsulin-like growth factor binding protein 5a0.028
f2rcoagulation factor II (thrombin) receptor0.027
cdh5cadherin 50.027
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor1.000
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)1.000
FN1fibronectin 11.000
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)1.000
CDC42cell division cycle 42 (GTP binding protein, 25kDa)1.000
PTPN1protein tyrosine phosphatase, non-receptor type 11.000
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.999
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.998
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.997
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.995
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.993
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.990
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.989
SHC1SHC (Src homology 2 domain containing) transforming protein 10.988
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.987
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.987
FGFR2fibroblast growth factor receptor 20.983
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.982
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.981
INSRinsulin receptor0.978
COL4A1collagen, type IV, alpha 10.972
IL1Binterleukin 1, beta0.971
LATlinker for activation of T cells0.971
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.966
ITGB5integrin, beta 50.965
METmet proto-oncogene (hepatocyte growth factor receptor)0.964
TEKTEK tyrosine kinase, endothelial0.961
FGFR1fibroblast growth factor receptor 10.957
TAL1T-cell acute lymphocytic leukemia 10.956
THBS1thrombospondin 10.955
CTGFconnective tissue growth factor0.948
COL1A1collagen, type I, alpha 10.944
CCR5chemokine (C-C motif) receptor 50.934
IL8interleukin 80.932
PLAURplasminogen activator, urokinase receptor0.917
PRKCAprotein kinase C, alpha0.916
PLCG1phospholipase C, gamma 10.916
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.907
COL1A2collagen, type I, alpha 20.904
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.901
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.892
SYKspleen tyrosine kinase0.885
FBLN1fibulin 10.884
YAP1Yes-associated protein 10.883
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.877
NCF2neutrophil cytosolic factor 20.862
ITGAVintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)0.854
PLAUplasminogen activator, urokinase0.854
JAG1jagged 10.853
AXLAXL receptor tyrosine kinase0.852
MMP14matrix metallopeptidase 14 (membrane-inserted)0.848
TGFB1transforming growth factor, beta 10.848
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.846
IRS1insulin receptor substrate 10.844
FYBFYN binding protein0.835
FBN1fibrillin 10.834
BMP2bone morphogenetic protein 20.829
CCL2chemokine (C-C motif) ligand 20.827
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.815
IGF1Rinsulin-like growth factor 1 receptor0.809
SNAP23synaptosomal-associated protein, 23kDa0.802
GRB10growth factor receptor-bound protein 100.791
NRP1neuropilin 10.779
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.770
IGFBP3insulin-like growth factor binding protein 30.770
INHBAinhibin, beta A0.730
LAMB1laminin, beta 10.701
FSTL1follistatin-like 10.681
TNCtenascin C0.675
POSTNperiostin, osteoblast specific factor0.673
PDIA3protein disulfide isomerase family A, member 30.673
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.669
CXCL3chemokine (C-X-C motif) ligand 30.669
COL7A1collagen, type VII, alpha 10.669
FYNFYN oncogene related to SRC, FGR, YES0.663
CXCL2chemokine (C-X-C motif) ligand 20.661
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.653
COL5A1collagen, type V, alpha 10.651
FGF1fibroblast growth factor 1 (acidic)0.650
CCL7chemokine (C-C motif) ligand 70.650
CXCL5chemokine (C-X-C motif) ligand 50.648
BAG3BCL2-associated athanogene 30.646
CXCL9chemokine (C-X-C motif) ligand 90.646
PTGISprostaglandin I2 (prostacyclin) synthase0.645
FGAfibrinogen alpha chain0.643
OSMRoncostatin M receptor0.642
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)0.641
LCKlymphocyte-specific protein tyrosine kinase0.636
CD44CD44 molecule (Indian blood group)0.635
DDR2discoidin domain receptor tyrosine kinase 20.627
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.621
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.619
VEGFCvascular endothelial growth factor C0.610
LAMC1laminin, gamma 1 (formerly LAMB2)0.606
LRP1low density lipoprotein receptor-related protein 10.595
PTRFpolymerase I and transcript release factor0.593
NRP2neuropilin 20.574
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Il1binterleukin 1 beta0.940
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.906
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.885
Irs1insulin receptor substrate 10.856
Col12a1collagen, type XII, alpha 10.825
Fgfr2fibroblast growth factor receptor 20.788
Bcl2B-cell CLL/lymphoma 20.756
Ccr5chemokine (C-C motif) receptor 50.740
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.710
Icam1intercellular adhesion molecule 10.680
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.667
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.641
Il8rbinterleukin 8 receptor, beta0.636
Metmet proto-oncogene0.616
Calcrlcalcitonin receptor-like0.571
S1pr2sphingosine-1-phosphate receptor 20.550
Lamc1laminin, gamma 10.541
Ccl2chemokine (C-C motif) ligand 20.541
Cd14CD14 molecule0.511
Jak1Janus kinase 10.497
Ccl4chemokine (C-C motif) ligand 40.463
Scarf2scavenger receptor class F, member 20.461
Cd44Cd44 molecule0.439
Nfianuclear factor I/A0.421
Dab2disabled homolog 2 (Drosophila)0.417
Slc1a1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 10.414
Vipvasoactive intestinal peptide0.407
Hckhemopoietic cell kinase0.402
Fgfr1Fibroblast growth factor receptor 10.401
Ednrbendothelin receptor type B0.397
Plauplasminogen activator, urokinase0.393
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.391
Gucy1b3guanylate cyclase 1, soluble, beta 30.389
Cxcl2chemokine (C-X-C motif) ligand 20.376
Itpr2inositol 1,4,5-triphosphate receptor, type 20.375
Il2rbinterleukin 2 receptor, beta0.366
Socs3suppressor of cytokine signaling 30.345
Flt1FMS-related tyrosine kinase 10.343
Epas1endothelial PAS domain protein 10.338
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.328
Crisp1cysteine-rich secretory protein 10.327
Bmp6bone morphogenetic protein 60.321
Cd38CD38 molecule0.319
Timp3TIMP metallopeptidase inhibitor 30.317
Itpr1inositol 1,4,5-triphosphate receptor, type 10.314
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.308
Kcng3potassium voltage-gated channel, subfamily G, member 30.296
Cpxm2carboxypeptidase X (M14 family), member 20.295
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.294
Ptger4prostaglandin E receptor 4 (subtype EP4)0.292
Nek9NIMA (never in mitosis gene a)- related kinase 90.290
Ednraendothelin receptor type A0.289
Ciitaclass II, major histocompatibility complex, transactivator0.287
Plekhn1pleckstrin homology domain containing, family N member 10.281
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.280
F2rl1coagulation factor II (thrombin) receptor-like 10.276
Cyp7a1cytochrome P450, family 7, subfamily a, polypeptide 10.275
Smad7SMAD family member 70.273
Ptafrplatelet-activating factor receptor0.272
Hoxa2homeo box A20.270
Nfixnuclear factor I/X (CCAAT-binding transcription factor)0.267
Olr1500olfactory receptor 15000.267
Tcf4transcription factor 40.260
Vav1vav 1 guanine nucleotide exchange factor0.259
Il6interleukin 60.256
Cd53Cd53 molecule0.249
Gja1gap junction protein, alpha 10.246
Csf1colony stimulating factor 1 (macrophage)0.246
Kcnj8potassium inwardly-rectifying channel, subfamily J, member 80.242
Gng7guanine nucleotide binding protein (G protein), gamma 70.238
Jak2Janus kinase 20.237
Pde4bphosphodiesterase 4B, cAMP specific0.235
Muc1mucin 1, cell surface associated0.233
Aqp4aquaporin 40.233
Sirpasignal-regulatory protein alpha0.232
Arandrogen receptor0.231
Slc1a3solute carrier family 1 (glial high affinity glutamate transporter), member 30.231
Gna12guanine nucleotide binding protein (G protein) alpha 120.226
Il1r1interleukin 1 receptor, type I0.225
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.224
Pde3aphosphodiesterase 3A, cGMP inhibited0.223
Il2rginterleukin 2 receptor, gamma0.223
Reg3bregenerating islet-derived 3 beta0.223
Adrb1adrenergic, beta-1-, receptor0.220
Ccr2chemokine (C-C motif) receptor 20.220
Il1ainterleukin 1 alpha0.218
F2rl3coagulation factor II (thrombin) receptor-like 30.216
Gzmkgranzyme K0.215
Pfn1profilin 10.215
Madcam1mucosal vascular addressin cell adhesion molecule 10.214
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.212
Sdcbp2syndecan binding protein (syntenin) 20.211
Smad3SMAD family member 30.207
Kif6kinesin family member 60.207
Slco2b1solute carrier organic anion transporter family, member 2b10.202
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.199
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism