The network for 'protein hydroxylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

protein hydroxylation

The addition of a hydroxy group to a protein amino acid.

NameDescriptionProbabilityFunc Analog Organism
PH4alphaNE2prolyl-4-hydroxylase-alpha NE20.388
lectin-46CbCG1652 gene product from transcript CG1652-RA0.340
CG12828CG12828 gene product from transcript CG12828-RA0.304
Spn7Serine protease inhibitor 70.299
CG18231CG18231 gene product from transcript CG18231-RB0.298
CG3004CG3004 gene product from transcript CG3004-RA0.266
CG31659CG31659 gene product from transcript CG31659-RA0.259
CG11608CG11608 gene product from transcript CG11608-RB0.212
BG642163CG34102 gene product from transcript CG34102-RA0.208
CG9522CG9522 gene product from transcript CG9522-RA0.180
PH4alphaNE3prolyl-4-hydroxylase-alpha NE30.161
CG10586CG10586 gene product from transcript CG10586-RA0.151
CG10041CG10041 gene product from transcript CG10041-RA0.143
CG12970CG12970 gene product from transcript CG12970-RA0.138
CG9168CG9168 gene product from transcript CG9168-RA0.136
CG10651CG10651 gene product from transcript CG10651-RA0.136
CG31419CG31419 gene product from transcript CG31419-RA0.134
CG9525CG9525 gene product from transcript CG9525-RA0.116
CG6168CG6168 gene product from transcript CG6168-RB0.114
CG11664CG11664 gene product from transcript CG11664-RA0.111
CG6690CG6690 gene product from transcript CG6690-RA0.104
CG6149CG6149 gene product from transcript CG6149-RB0.100
CG18281CG18281 gene product from transcript CG18281-RA0.096
CG42481CG42481 gene product from transcript CG42481-RA0.091
CG18234CG18234 gene product from transcript CG18234-RC0.091
lectin-21CaCG2826 gene product from transcript CG2826-RA0.089
CG15635CG15635 gene product from transcript CG15635-RB0.088
Acp29ABAccessory gland-specific peptide 29AB0.086
PdhPhotoreceptor dehydrogenase0.083
CG7304CG7304 gene product from transcript CG7304-RA0.075
scfsupercoiling factor0.075
neroCG2245 gene product from transcript CG2245-RA0.074
Acp76AAccessory gland-specific peptide 76A0.073
Acp70AAccessory gland peptide 70A0.073
CG18672CG18672 gene product from transcript CG18672-RA0.072
CG11977CG11977 gene product from transcript CG11977-RB0.072
CG11637CG11637 gene product from transcript CG11637-RA0.070
CG11112CG11112 gene product from transcript CG11112-RC0.069
CG11828CG11828 gene product from transcript CG11828-RC0.069
Prp38pre-mRNA processing factor 380.068
CG15539CG15539 gene product from transcript CG15539-RA0.066
CG32833CG32833 gene product from transcript CG32833-RA0.066
CG1701CG1701 gene product from transcript CG1701-RB0.065
lectin-30ACG17011 gene product from transcript CG17011-RA0.064
CG33259CG33259 gene product from transcript CG33259-RA0.061
CG9194CG9194 gene product from transcript CG9194-RA0.061
CG31016CG31016 gene product from transcript CG31016-RB0.059
CG18581CG18581 gene product from transcript CG18581-RA0.057
CG15864CG15864 gene product from transcript CG15864-RB0.056
CG11037CG11037 gene product from transcript CG11037-RA0.054
CG14034CG14034 gene product from transcript CG14034-RB0.052
CG18233CG18233 gene product from transcript CG18233-RA0.051
CG2111CG2111 gene product from transcript CG2111-RA0.049
CG5267CG5267 gene product from transcript CG5267-RA0.048
CG13622CG13622 gene product from transcript CG13622-RB0.047
Spn77BcSerpin 77Bc0.046
CG9948CG9948 gene product from transcript CG9948-RA0.046
nimC1nimrod C10.045
CG12522CG12522 gene product from transcript CG12522-RA0.044
CG18258CG18258 gene product from transcript CG18258-RA0.043
CG31976CG31976 gene product from transcript CG31976-RB0.043
CG14193CG14193 gene product from transcript CG14193-RA0.042
Ugt58FaCG4414 gene product from transcript CG4414-RA0.042
CG17472CG17472 gene product from transcript CG17472-RA0.041
CG6071CG6071 gene product from transcript CG6071-RA0.040
CG13557CG13557 gene product from transcript CG13557-RA0.040
CG4822CG4822 gene product from transcript CG4822-RB0.039
CG2983CG2983 gene product from transcript CG2983-RA0.039
CG4271CG4271 gene product from transcript CG4271-RA0.039
Acp53EaAccessory gland-specific peptide 53Ea0.038
CG30259CG30259 gene product from transcript CG30259-RA0.038
Acp32CDAccessory gland-specific peptide 32CD0.037
CG17780CG17780 gene product from transcript CG17780-RC0.037
Spn2Serine protease inhibitor 20.036
Ets65AEts at 65A0.036
CG8021CG8021 gene product from transcript CG8021-RA0.036
CG10853CG10853 gene product from transcript CG10853-RA0.035
Ctr1BCopper transporter 1B0.034
Acp62FAccessory gland peptide 62F0.034
CG16800CG16800 gene product from transcript CG16800-RB0.033
Cad88CCG3389 gene product from transcript CG3389-RA0.033
CG7579CG7579 gene product from transcript CG7579-RA0.033
CG31515CG31515 gene product from transcript CG31515-RA0.033
msopamale-specific opa containing gene0.033
CG14216CG14216 gene product from transcript CG14216-RA0.032
CG32199CG32199 gene product from transcript CG32199-RA0.032
CG32379CG32379 gene product from transcript CG32379-RB0.032
CG31883CG31883 gene product from transcript CG31883-RA0.031
CG34256CG34256 gene product from transcript CG34256-RB0.031
CG8036CG8036 gene product from transcript CG8036-RB0.029
CG34171CG34171 gene product from transcript CG34171-RA0.029
CG3457CG3457 gene product from transcript CG3457-RA0.029
Acp36DEAccessory gland peptide 36DE0.028
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
eef-1A.2Protein EEF-1A.20.174
hsp-3Protein HSP-30.131
tag-320Protein TAG-3200.092
phy-2Protein PHY-20.081
epi-1Protein EPI-10.063
dpy-18Protein DPY-180.046
aagr-4Protein AAGR-40.040
uggt-1Protein UGGT-10.039
nucb-1Protein NUCB-10.038
fasn-1Protein FASN-10.030
trap-3Protein TRAP-30.027
F47B7.2Protein F47B7.20.027
Y71G12B.6Protein Y71G12B.60.027
F49H12.5Protein F49H12.50.020
cut-2Protein CUT-20.016
T14G8.3Protein T14G8.30.016
alh-13Protein ALH-130.014
noah-1Protein NOAH-10.014
nra-4Protein NRA-40.013
hke-4.2Protein HKE-4.20.013
pdi-3Protein PDI-30.012
pcca-1Protein PCCA-10.011
let-268Protein LET-2680.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.996
SSX4synovial sarcoma, X breakpoint 40.802
PDIA3protein disulfide isomerase family A, member 30.728
ERO1LERO1-like (S. cerevisiae)0.689
EGLN1egl nine homolog 1 (C. elegans)0.541
PDIA4protein disulfide isomerase family A, member 40.256
EPAS1endothelial PAS domain protein 10.254
VHLvon Hippel-Lindau tumor suppressor0.197
EGLN3egl nine homolog 3 (C. elegans)0.118
PLOD1procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 10.085
HM13histocompatibility (minor) 130.079
U2AF1U2 small nuclear RNA auxiliary factor 10.074
ZCCHC17zinc finger, CCHC domain containing 170.057
ARNTaryl hydrocarbon receptor nuclear translocator0.036
GBE1glucan (1,4-alpha-), branching enzyme 10.033
PKM2pyruvate kinase, muscle0.023
PLOD2procollagen-lysine, 2-oxoglutarate 5-dioxygenase 20.023
OS9osteosarcoma amplified 9, endoplasmic reticulum lectin0.021
SERPINH1serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)0.020
PLOD3procollagen-lysine, 2-oxoglutarate 5-dioxygenase 30.019
GLT25D1glycosyltransferase 25 domain containing 10.019
ERO1LBERO1-like beta (S. cerevisiae)0.017
PPIBpeptidylprolyl isomerase B (cyclophilin B)0.016
TNKS2tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 20.014
LEPRE1leucine proline-enriched proteoglycan (leprecan) 10.013
P4HA2prolyl 4-hydroxylase, alpha polypeptide II0.013
ASB13ankyrin repeat and SOCS box containing 130.012
TNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase0.011
DCBLD1discoidin, CUB and LCCL domain containing 10.011
BRD4bromodomain containing 40.011
HIF1ANhypoxia inducible factor 1, alpha subunit inhibitor0.011
SEPT9septin 90.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.991
Kdelr3KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 30.619
Lepre1leprecan 10.560
Leprel4leprecan-like 40.541
Fkbp10FK506 binding protein 100.436
Col4a2collagen, type IV, alpha 20.433
Emilin1elastin microfibril interfacer 10.427
P4ha1procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide0.417
Sepn1selenoprotein N, 10.402
Fkbp9FK506 binding protein 90.397
P4ha2procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide0.397
Surf4surfeit gene 40.390
Col4a1collagen, type IV, alpha 10.335
Lama4laminin, alpha 40.285
Pcolceprocollagen C-endopeptidase enhancer protein0.280
Plod3procollagen-lysine, 2-oxoglutarate 5-dioxygenase 30.250
Sparcsecreted acidic cysteine rich glycoprotein0.235
Rcn3reticulocalbin 3, EF-hand calcium binding domain0.222
Sec31aSec31 homolog A (S. cerevisiae)0.221
Maged1melanoma antigen, family D, 10.206
Rpn2ribophorin II0.195
Hif1ahypoxia inducible factor 1, alpha subunit0.165
Ckap4cytoskeleton-associated protein 40.152
Mmp2matrix metallopeptidase 20.150
Creb3l2cAMP responsive element binding protein 3-like 20.145
Col6a1collagen, type VI, alpha 10.143
Col6a3collagen, type VI, alpha 30.134
Ppicpeptidylprolyl isomerase C0.132
Copz2coatomer protein complex, subunit zeta 20.129
Chst14carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 140.127
Glt25d1glycosyltransferase 25 domain containing 10.127
Col5a1collagen, type V, alpha 10.119
Fam114a1family with sequence similarity 114, member A10.116
Txndc5thioredoxin domain containing 50.109
Fbn1fibrillin 10.103
Lamc1laminin, gamma 10.101
Olfml3olfactomedin-like 30.100
Prnpprion protein0.094
Col1a2collagen, type I, alpha 20.092
Vegfavascular endothelial growth factor A0.091
Bmp1bone morphogenetic protein 10.090
Col6a2collagen, type VI, alpha 20.089
Efemp2epidermal growth factor-containing fibulin-like extracellular matrix protein 20.088
Lamb2laminin, beta 20.087
Mxra8matrix-remodelling associated 80.082
Col1a1collagen, type I, alpha 10.077
Angptl2angiopoietin-like 20.075
Nucb1nucleobindin 10.074
Ddah2dimethylarginine dimethylaminohydrolase 20.074
Col5a2collagen, type V, alpha 20.073
Pdia5protein disulfide isomerase associated 50.071
B3gnt9-psUDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9, pseudogene0.070
Rab34RAB34, member of RAS oncogene family0.069
Bag3BCL2-associated athanogene 30.062
Leprel2leprecan-like 20.062
Kdelr2KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 20.061
Slc39a7solute carrier family 39 (zinc transporter), member 70.061
Plod2procollagen lysine, 2-oxoglutarate 5-dioxygenase 20.060
Sec61a1Sec61 alpha 1 subunit (S. cerevisiae)0.060
C1qtnf6C1q and tumor necrosis factor related protein 60.059
Pofut2protein O-fucosyltransferase 20.058
Bhlhe40basic helix-loop-helix family, member e400.058
Itgb5integrin beta 50.058
Crtapcartilage associated protein0.057
Vkorc1vitamin K epoxide reductase complex, subunit 10.057
Prkcshprotein kinase C substrate 80K-H0.057
Col3a1collagen, type III, alpha 10.050
Prkcdbpprotein kinase C, delta binding protein0.050
Hsph1heat shock 105kDa/110kDa protein 10.049
Dnajb1DnaJ (Hsp40) homolog, subfamily B, member 10.048
Dpagt1dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)0.044
Frmd6FERM domain containing 60.043
Cd248CD248 antigen, endosialin0.043
Epas1endothelial PAS domain protein 10.043
Igfbp4insulin-like growth factor binding protein 40.043
Loxl2lysyl oxidase-like 20.042
Serpinf1serine (or cysteine) peptidase inhibitor, clade F, member 10.041
Tmem119transmembrane protein 1190.039
Lamb1laminin B10.039
Slc39a13solute carrier family 39 (metal ion transporter), member 130.038
Fstl1follistatin-like 10.037
Cul7cullin 70.037
Cpxm1carboxypeptidase X 1 (M14 family)0.036
Gpr124G protein-coupled receptor 1240.036
Loxl1lysyl oxidase-like 10.036
Npr2natriuretic peptide receptor 20.036
Cspg4chondroitin sulfate proteoglycan 40.036
Dag1dystroglycan 10.035
Gpx7glutathione peroxidase 70.033
Lman1lectin, mannose-binding, 10.033
Pmp22peripheral myelin protein 220.033
P4hbprolyl 4-hydroxylase, beta polypeptide0.032
Capns1calpain, small subunit 10.032
Bicc1bicaudal C homolog 1 (Drosophila)0.031
P4htmprolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)0.030
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism