The network for 'xenobiotic catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

xenobiotic catabolic process

The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.

NameDescriptionProbabilityFunc Analog Organism
Ugt35aUDP-glycosyltransferase 35a0.985
Cyp6a21CG10247 gene product from transcript CG10247-RA0.893
CG13310CG13310 gene product from transcript CG13310-RA0.874
JhI-26Juvenile hormone-inducible protein 260.823
Cyp12a4CG6042 gene product from transcript CG6042-RA0.789
Cyp4e2Cytochrome P450-4e20.764
Cyp6d5CG3050 gene product from transcript CG3050-RA0.758
CG9360CG9360 gene product from transcript CG9360-RA0.636
CG10562CG10562 gene product from transcript CG10562-RA0.603
Cyp6a9Cytochrome P450-6a90.589
Cyp9b2Cytochrome P450-9b20.503
Cyp12e1CG14680 gene product from transcript CG14680-RC0.498
CG4880CG4880 gene product from transcript CG4880-RA0.489
GstE6Glutathione S transferase E60.484
CG6830CG6830 gene product from transcript CG6830-RA0.465
Cyp6d4CG12800 gene product from transcript CG12800-RA0.461
Cyp4ac1CG14032 gene product from transcript CG14032-RA0.408
Cyp6a2Cytochrome P450-6a20.395
Ugt86DaCG18578 gene product from transcript CG18578-RA0.367
Cyp6a23CG10242 gene product from transcript CG10242-RA0.346
CG12672CG12672 gene product from transcript CG12672-RA0.341
CG6834CG6834 gene product from transcript CG6834-RA0.328
LvpDLarval visceral protein D0.305
Cyp28d1CG10833 gene product from transcript CG10833-RA0.296
CG2064CG2064 gene product from transcript CG2064-RA0.292
CG7272CG7272 gene product from transcript CG7272-RA0.290
homerCG11324 gene product from transcript CG11324-RC0.269
Ugt36BcCG17932 gene product from transcript CG17932-RB0.268
Cyp4p1Cytochrome P450-4p10.252
Cyp6a13CG2397 gene product from transcript CG2397-RA0.218
Cyp12a5CG11821 gene product from transcript CG11821-RA0.194
EpacCG34392 gene product from transcript CG34392-RC0.192
CG10560CG10560 gene product from transcript CG10560-RA0.192
CG10550CG10550 gene product from transcript CG10550-RB0.188
CG3759CG3759 gene product from transcript CG3759-RB0.188
CG7730CG7730 gene product from transcript CG7730-RC0.183
Cyp9f2CG11466 gene product from transcript CG11466-RB0.182
Acph-1Acid phosphatase 10.181
Jheh3Juvenile hormone epoxide hydrolase 30.176
CG4723CG4723 gene product from transcript CG4723-RA0.175
TotATurandot A0.170
Jheh1Juvenile hormone epoxide hydrolase 10.160
CG16898CG16898 gene product from transcript CG16898-RA0.159
Est-QEsterase Q0.159
CG14457CG14457 gene product from transcript CG14457-RA0.158
CG4630CG4630 gene product from transcript CG4630-RA0.152
Ilp4Insulin-like peptide 40.147
CG11149CG11149 gene product from transcript CG11149-RD0.143
CG7979CG7979 gene product from transcript CG7979-RA0.141
CG6908CG6908 gene product from transcript CG6908-RA0.134
Rh50CG7499 gene product from transcript CG7499-RA0.129
CG6465CG6465 gene product from transcript CG6465-RA0.128
CG9512CG9512 gene product from transcript CG9512-RA0.127
Vha68-1CG12403 gene product from transcript CG12403-RA0.126
Ugt86DdCG6633 gene product from transcript CG6633-RB0.125
mus81CG3026 gene product from transcript CG3026-RA0.123
Ugt86DhCG4772 gene product from transcript CG4772-RA0.119
CG13407CG13407 gene product from transcript CG13407-RA0.117
CG30494CG30494 gene product from transcript CG30494-RA0.116
CG15408CG15408 gene product from transcript CG15408-RA0.113
Syx4Syntaxin 40.112
Cyp6a8Cytochrome P450-6a80.111
CG15784CG15784 gene product from transcript CG15784-RA0.111
Ugt86DjCG15902 gene product from transcript CG15902-RA0.108
CG5361CG5361 gene product from transcript CG5361-RA0.105
CG4653CG4653 gene product from transcript CG4653-RA0.105
Ugt86DcCG4739 gene product from transcript CG4739-RA0.103
GstE3Glutathione S transferase E30.102
CG13658CG13658 gene product from transcript CG13658-RB0.100
CG4302CG4302 gene product from transcript CG4302-RA0.097
CG8679CG8679 gene product from transcript CG8679-RA0.095
CG5999CG5999 gene product from transcript CG5999-RB0.094
Ilp2Insulin-like peptide 20.094
CG11967CG11967 gene product from transcript CG11967-RA0.093
CG16732CG16732 gene product from transcript CG16732-RB0.091
Cyp4ac3CG14031 gene product from transcript CG14031-RA0.091
Fkbp13CG9847 gene product from transcript CG9847-RC0.088
CG17109CG17109 gene product from transcript CG17109-RA0.087
Cyp9b1Cytochrome P450-9b10.087
CG15661CG15661 gene product from transcript CG15661-RA0.087
Cyp9h1CG17577 gene product from transcript CG17577-RA0.087
nAcRalpha-96Aanicotinic Acetylcholine Receptor alpha 96Aa0.086
CG3301CG3301 gene product from transcript CG3301-RB0.085
CG5724CG5724 gene product from transcript CG5724-RA0.084
GstE5Glutathione S transferase E50.083
Tsp42EdTetraspanin 42Ed0.082
CG14856CG14856 gene product from transcript CG14856-RA0.081
CG17028CG17028 gene product from transcript CG17028-RA0.079
nimB2nimrod B20.079
CG5819CG5819 gene product from transcript CG5819-RA0.076
NaCP60ENa channel protein 60E0.075
CG31104CG31104 gene product from transcript CG31104-RA0.075
CG6656CG6656 gene product from transcript CG6656-RA0.074
CG5527CG5527 gene product from transcript CG5527-RA0.073
CG17739CG17739 gene product from transcript CG17739-RA0.073
CG1387CG1387 gene product from transcript CG1387-RA0.073
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
GSTM2glutathione S-transferase mu 2 (muscle)0.999
GSTM4glutathione S-transferase mu 40.948
GSTM1glutathione S-transferase mu 10.933
GSTM3glutathione S-transferase mu 3 (brain)0.050
PSMA1proteasome (prosome, macropain) subunit, alpha type, 10.028
CYP3A7cytochrome P450, family 3, subfamily A, polypeptide 70.013
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gstm1glutathione S-transferase, mu 10.996
Gsta2glutathione S-transferase, alpha 2 (Yc2)0.991
Fmo5flavin containing monooxygenase 50.980
Gstm3glutathione S-transferase, mu 30.977
Cyp2a12cytochrome P450, family 2, subfamily a, polypeptide 120.965
Otcornithine transcarbamylase0.965
Cyp2b10cytochrome P450, family 2, subfamily b, polypeptide 100.963
Gsta3glutathione S-transferase, alpha 30.959
Cyp2c29cytochrome P450, family 2, subfamily c, polypeptide 290.897
Gstm6glutathione S-transferase, mu 60.833
Gm3776predicted gene 37760.830
Gsta4glutathione S-transferase, alpha 40.826
Sult1d1sulfotransferase family 1D, member 10.825
Ces1dcarboxylesterase 1D0.744
Aldh1a7aldehyde dehydrogenase family 1, subfamily A70.660
Ces1gcarboxylesterase 1G0.630
Cyp2c50cytochrome P450, family 2, subfamily c, polypeptide 500.620
Cyp3a13cytochrome P450, family 3, subfamily a, polypeptide 130.608
Cps1carbamoyl-phosphate synthetase 10.588
Cyp2b9cytochrome P450, family 2, subfamily b, polypeptide 90.555
Ephx1epoxide hydrolase 1, microsomal0.551
Cyp3a44cytochrome P450, family 3, subfamily a, polypeptide 440.503
Hsd3b7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 70.487
Cyp3a11cytochrome P450, family 3, subfamily a, polypeptide 110.462
Ugt2b34UDP glucuronosyltransferase 2 family, polypeptide B340.457
Gstt1glutathione S-transferase, theta 10.442
Cyp2c38cytochrome P450, family 2, subfamily c, polypeptide 380.399
Gstm4glutathione S-transferase, mu 40.386
Cyp3a41bcytochrome P450, family 3, subfamily a, polypeptide 41B0.353
Cyp2c39cytochrome P450, family 2, subfamily c, polypeptide 390.290
Cyp4a14cytochrome P450, family 4, subfamily a, polypeptide 140.289
Cyp3a25cytochrome P450, family 3, subfamily a, polypeptide 250.287
Aassaminoadipate-semialdehyde synthase0.279
Tmem205transmembrane protein 2050.262
Ugt2b5UDP glucuronosyltransferase 2 family, polypeptide B50.231
Adh7alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide0.226
Defb1defensin beta 10.215
Iydiodotyrosine deiodinase0.214
Adh1alcohol dehydrogenase 1 (class I)0.213
Gstm2glutathione S-transferase, mu 20.202
Sult1b1sulfotransferase family 1B, member 10.192
Nr1i2nuclear receptor subfamily 1, group I, member 20.188
Baatbile acid-Coenzyme A: amino acid N-acyltransferase0.182
Cyp2c55cytochrome P450, family 2, subfamily c, polypeptide 550.167
Ugt2a3UDP glucuronosyltransferase 2 family, polypeptide A30.156
Galmgalactose mutarotase0.139
Ces2gcarboxylesterase 2G0.138
G6pcglucose-6-phosphatase, catalytic0.136
Pik3c2gphosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide0.133
Cyp2f2cytochrome P450, family 2, subfamily f, polypeptide 20.132
Cfhr1complement factor H-related 10.130
S100a1S100 calcium binding protein A10.124
Nqo1NAD(P)H dehydrogenase, quinone 10.122
Dpyddihydropyrimidine dehydrogenase0.121
Vsig4V-set and immunoglobulin domain containing 40.118
Cyp4a31cytochrome P450, family 4, subfamily a, polypeptide 310.118
Akr1d1aldo-keto reductase family 1, member D10.116
Acox2acyl-Coenzyme A oxidase 2, branched chain0.114
Akr1c6aldo-keto reductase family 1, member C60.107
Mgst1microsomal glutathione S-transferase 10.105
Inmtindolethylamine N-methyltransferase0.101
Tdo2tryptophan 2,3-dioxygenase0.099
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.099
Abcc2ATP-binding cassette, sub-family C (CFTR/MRP), member 20.097
Pon1paraoxonase 10.094
Aldh1a1aldehyde dehydrogenase family 1, subfamily A10.092
Selenbp1selenium binding protein 10.092
Cyp3a16cytochrome P450, family 3, subfamily a, polypeptide 160.092
Rdh7retinol dehydrogenase 70.091
Cmblcarboxymethylenebutenolidase-like (Pseudomonas)0.084
Ugt2b36UDP glucuronosyltransferase 2 family, polypeptide B360.083
Ces1ecarboxylesterase 1E0.081
Pxmp2peroxisomal membrane protein 20.080
Cyp3a41acytochrome P450, family 3, subfamily a, polypeptide 41A0.079
Cyp4b1cytochrome P450, family 4, subfamily b, polypeptide 10.075
Gstk1glutathione S-transferase kappa 10.074
CrpC-reactive protein, pentraxin-related0.070
Slco1b2solute carrier organic anion transporter family, member 1b20.068
Slc22a1solute carrier family 22 (organic cation transporter), member 10.067
Ces2ecarboxylesterase 2E0.066
Mpzl2myelin protein zero-like 20.063
Bbox1butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)0.062
Cyp7a1cytochrome P450, family 7, subfamily a, polypeptide 10.055
Slc2a2solute carrier family 2 (facilitated glucose transporter), member 20.054
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.053
Ugt2b35UDP glucuronosyltransferase 2 family, polypeptide B350.051
Pm20d1peptidase M20 domain containing 10.050
Cyp4a12acytochrome P450, family 4, subfamily a, polypeptide 12a0.050
Slc23a1solute carrier family 23 (nucleobase transporters), member 10.048
Ugt1a1UDP glucuronosyltransferase 1 family, polypeptide A10.048
Aldobaldolase B, fructose-bisphosphate0.047
Cyp2c37cytochrome P450, family 2. subfamily c, polypeptide 370.046
Retsatretinol saturase (all trans retinol 13,14 reductase)0.046
Cyp2c54cytochrome P450, family 2, subfamily c, polypeptide 540.046
Copz2coatomer protein complex, subunit zeta 20.045
Slc22a18solute carrier family 22 (organic cation transporter), member 180.044
Nat1N-acetyl transferase 10.044
Bhmtbetaine-homocysteine methyltransferase0.044
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Gstm1glutathione S-transferase mu 11.000
Ugt2b5UDP glucuronosyltransferase 2 family, polypeptide B50.975
Ephx1epoxide hydrolase 1, microsomal0.938
Mgst1microsomal glutathione S-transferase 10.827
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.753
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.614
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.562
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.552
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.545
Mgst2microsomal glutathione S-transferase 20.515
Gsta5glutathione S-transferase Yc2 subunit0.432
Sult2al1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 10.364
Cyp2b1cytochrome P450, family 2, subfamily b, polypeptide 10.267
LOC100361547Cytochrome P450, family 2, subfamily c, polypeptide 7-like0.234
Abcc2ATP-binding cassette, subfamily C (CFTR/MRP), member 20.219
Cyp2c12cytochrome P450, family 2, subfamily c, polypeptide 120.207
Gstp1glutathione S-transferase pi 10.205
Gsta2glutathione S-transferase A20.174
Gsta3glutathione S-transferase A30.163
Ugt2b36UDP glucuronosyltransferase 2 family, polypeptide B360.157
Cyp3a2cytochrome P450, family 3, subfamily a, polypeptide 20.153
Otcornithine carbamoyltransferase0.115
LOC494499LOC494499 protein0.108
Acsm2acyl-CoA synthetase medium-chain family member 20.108
Ces1ccarboxylesterase 1C0.105
Ces1ecarboxylesterase 1E0.099
Akr7a3aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)0.098
Ugt2b37UDP-glucuronosyltransferase 2 family, member 370.089
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.089
LOC293989cytochrome P450-like0.078
Apobapolipoprotein B0.077
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.076
Ugt1a3UDP glycosyltransferase 1 family, polypeptide A30.073
Gstm2glutathione S-transferase mu 20.070
Cyb5acytochrome b5 type A (microsomal)0.068
Abcb11ATP-binding cassette, subfamily B (MDR/TAP), member 110.057
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.051
Ugt1a5UDP glucuronosyltransferase 1 family, polypeptide A50.048
Akr1c14aldo-keto reductase family 1, member C140.048
Sult1e1sulfotransferase family 1E, estrogen-preferring, member 10.048
Cyp1a1cytochrome P450, family 1, subfamily a, polypeptide 10.048
LOC100361864UDP-glucuronosyltransferase 2B3-like0.047
Cyp4a2cytochrome P450, family 4, subfamily a, polypeptide 20.047
Pctpphosphatidylcholine transfer protein0.046
Ugt1a7cUDP glucuronosyltransferase 1 family, polypeptide A7C0.043
Ces1fcarboxylesterase 1F0.042
Cyp3a9cytochrome P450, family 3, subfamily a, polypeptide 90.042
Il1ainterleukin 1 alpha0.038
Ugt1a1UDP glucuronosyltransferase 1 family, polypeptide A10.033
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.033
Cyb5r3cytochrome b5 reductase 30.032
Selenbp1selenium binding protein 10.031
Fabp1fatty acid binding protein 1, liver0.030
Fabp2fatty acid binding protein 2, intestinal0.030
Nat2N-acetyltransferase 20.030
Dhfrdihydrofolate reductase0.026
Cyp2c11cytochrome P450, subfamily 2, polypeptide 110.026
Cyp2a2cytochrome P450, family 2, subfamily a, polypeptide 20.026
Slco1a5solute carrier organic anion transporter family, member 1a50.025
Sult2a1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 10.024
Clca4chloride channel accessory 40.024
Cyp2b2cytochrome P450, family 2, subfamily b, polypeptide 20.023
Cyp2c13cytochrome P450, family 2, subfamily c, polypeptide 130.022
Znf394zinc finger protein 3940.021
Pigrpolymeric immunoglobulin receptor0.021
Hpd4-hydroxyphenylpyruvate dioxygenase0.019
Gstm7glutathione S-transferase, mu 70.019
Nqo1NAD(P)H dehydrogenase, quinone 10.019
Vom1r102vomeronasal 1 receptor 1020.018
Mbl2mannose-binding lectin (protein C) 20.018
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.018
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.018
Sult1c3sulfotransferase family, cytosolic, 1C, member 30.017
Aldh1a7aldehyde dehydrogenase family 1, subfamily A70.016
Acaa1bacetyl-Coenzyme A acyltransferase 1B0.016
Dnah1dynein, axonemal, heavy chain 10.016
Haao3-hydroxyanthranilate 3,4-dioxygenase0.016
Nr1h4nuclear receptor subfamily 1, group H, member 40.015
Sult2a2sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 20.015
Klkb1kallikrein B, plasma 10.014
Aadacarylacetamide deacetylase (esterase)0.014
Sisucrase-isomaltase (alpha-glucosidase)0.014
Gstt1glutathione S-transferase theta 10.014
Klrc2killer cell lectin-like receptor subfamily C, member 20.013
Galnt5UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)0.013
Ugt1a2UDP glucuronosyltransferase 1 family, polypeptide A20.013
Ugt1a8UDP glycosyltransferase 1 family, polypeptide A80.012
Akr1c18aldo-keto reductase family 1, member C180.012
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.012
S100a1S100 calcium binding protein A10.011
Gstm5glutathione S-transferase, mu 50.011
Aqp9aquaporin 90.011
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.011
Dpyddihydropyrimidine dehydrogenase0.011
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.011
Cyp2d3cytochrome P450, family 2, subfamily d, polypeptide 30.011
Cd46CD46 molecule, complement regulatory protein0.011
Qdprquinoid dihydropteridine reductase0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism