The network for 'cullin deneddylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cullin deneddylation

The modification of cullins by removal of ubiquitin-like protein NEDD8 (RUB1).

NameDescriptionProbabilityFunc Analog Organism
CSN4COP9 complex homolog subunit 41.000
CSN5COP9 complex homolog subunit 50.995
CSN7COP9 complex homolog subunit 70.978
pontpontin0.677
alienCG9556 gene product from transcript CG9556-RB0.475
sds22CG5851 gene product from transcript CG5851-RA0.419
MED6Mediator complex subunit 60.368
CSN3COP9 complex homolog subunit 30.350
Pp2A-29BProtein phosphatase 2A at 29B0.327
Rpn6Proteasome p44.5 subunit0.178
Rpn11CG18174 gene product from transcript CG18174-RA0.167
Nedd8CG10679 gene product from transcript CG10679-RA0.105
Rpt4CG3455 gene product from transcript CG3455-RA0.099
Tbp-1Tat-binding protein-10.074
Uch-L3Ubiquitin C-terminal hydrolase0.070
TfIIA-LTranscription factor IIA L0.066
Rpn9CG10230 gene product from transcript CG10230-RB0.061
wcdwicked0.052
AlyCG1101 gene product from transcript CG1101-RA0.051
CG5384CG5384 gene product from transcript CG5384-RA0.042
captcapulet0.037
CG17282CG17282 gene product from transcript CG17282-RA0.034
FppsFarnesyl pyrophosphate synthase0.032
Nup50Nucleoporin 500.030
CSN8COP9 complex homolog subunit 80.030
Bap55Brahma associated protein 55kD0.029
CG8223CG8223 gene product from transcript CG8223-RA0.028
pashapartner of drosha0.028
CG5355CG5355 gene product from transcript CG5355-RA0.026
CG5222CG5222 gene product from transcript CG5222-RA0.025
CSN1bCOP9 complex homolog subunit 1 b0.024
CSN6COP9 complex homolog subunit 60.024
tsutsunagi0.022
Vps36Vacuolar protein sorting 360.022
CG5857CG5857 gene product from transcript CG5857-RA0.020
effeffete0.020
noinoisette0.018
SceSex combs extra0.017
CG7747CG7747 gene product from transcript CG7747-RA0.017
p115CG1422 gene product from transcript CG1422-RA0.016
NitFhitNitrilase and fragile histidine triad fusion protein0.016
Trc8CG2304 gene product from transcript CG2304-RB0.016
Prp19CG5519 gene product from transcript CG5519-RA0.015
ATPCLATP citrate lyase0.015
Prosbeta3Proteasome beta3 subunit0.014
CG5585CG5585 gene product from transcript CG5585-RA0.013
CG10979CG10979 gene product from transcript CG10979-RA0.013
UchUbiquitin carboxy-terminal hydrolase0.013
Rpn3Regulatory particle non-ATPase 30.013
CG7265CG7265 gene product from transcript CG7265-RA0.012
CG9705CG9705 gene product from transcript CG9705-RA0.012
CG5676CG5676 gene product from transcript CG5676-RA0.012
CG8735CG8735 gene product from transcript CG8735-RA0.010
CG5198CG5198 gene product from transcript CG5198-RA0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)1.000
COPS6COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)0.998
COPS4COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)0.997
COPS2COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)0.993
COPS3COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)0.947
COPS8COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)0.880
GFERgrowth factor, augmenter of liver regeneration0.595
GPS1G protein pathway suppressor 10.531
CUL1cullin 10.478
COPS7ACOP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)0.119
CUL2cullin 20.089
TCEB1transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)0.080
RBX1ring-box 1, E3 ubiquitin protein ligase0.050
DDB1damage-specific DNA binding protein 1, 127kDa0.041
NEDD8neural precursor cell expressed, developmentally down-regulated 80.035
RFWD2ring finger and WD repeat domain 20.022
CUL4Acullin 4A0.019
LRR1leucine rich repeat protein 10.018
MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor)0.012
CUL4Bcullin 4B0.012
CUL3cullin 30.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
RRI1Rri1p0.989
CSI1Csi1p0.419
PCI8Pci8p0.292
CSN9Csn9p0.175
RPN2Rpn2p0.043
SKP1Skp1p0.035
YJR084Whypothetical protein0.030
SRD1Srd1p0.023
LEU2Leu2p0.020
ARP10Arp10p0.019
YOL038C-Ahypothetical protein0.019
YLR264C-Ahypothetical protein0.018
YLR162Whypothetical protein0.017
SPL2Spl2p0.017
MER1Mer1p0.016
YAR068Whypothetical protein0.015
CUP1-1Cup1-1p0.015
ATP6Atp6p0.014
YBR013Chypothetical protein0.014
HXT3Hxt3p0.014
YPR157Whypothetical protein0.014
ZPS1Zps1p0.013
HPF1Hpf1p0.013
AUA1Aua1p0.013
YLR042Chypothetical protein0.012
CPD1Cpd1p0.012
YOL013W-Ahypothetical protein0.012
FMT1Fmt1p0.012
YML003Whypothetical protein0.012
IZH4Izh4p0.011
UPS3Ups3p0.011
ICS2Ics2p0.011
MF(ALPHA)2Mf(alpha)2p0.011
OPT2Opt2p0.010
RRI2Rri2p0.010