The network for 'negative regulation of neuron apoptotic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of neuron apoptotic process

Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.

NameDescriptionProbabilityFunc Analog Organism
p53CG33336 gene product from transcript CG33336-RB0.155
Ube3aUbiquitin protein ligase E3A0.102
RpL5Ribosomal protein L50.088
Ced-12CG5336 gene product from transcript CG5336-RA0.072
argosCG4531 gene product from transcript CG4531-RA0.072
e(y)3enhancer of yellow 30.065
Sod2Superoxide dismutase 2 (Mn)0.064
crolcrooked legs0.052
mib1mind bomb 10.048
Hnf4Hepatocyte nuclear factor 40.046
oho23Bovergrown hematopoietic organs at 23B0.046
svpseven up0.043
eyaeyes absent0.038
aopanterior open0.037
RhebCG1081 gene product from transcript CG1081-RA0.034
Vap-33-1CG5014 gene product from transcript CG5014-RB0.034
LamCLamin C0.034
AP-2CG7807 gene product from transcript CG7807-RB0.033
wbwing blister0.032
cindrCIN85 and CD2AP orthologue0.031
Atg1Autophagy-specific gene 10.030
bab2CG9102 gene product from transcript CG9102-RA0.029
eastenhanced adult sensory threshold0.029
drkdownstream of receptor kinase0.029
tefutelomere fusion0.026
Su(H)Suppressor of Hairless0.024
PTP-ERProtein tyrosine phosphatase-ERK/Enhancer of Ras10.023
Pi3K92ECG4141 gene product from transcript CG4141-RB0.023
RhoGEF2CG9635 gene product from transcript CG9635-RF0.021
EcREcdysone receptor0.019
Arp66BActin-related protein 66B0.019
ThorCG8846 gene product from transcript CG8846-RA0.018
Sema-1aCG18405 gene product from transcript CG18405-RD0.018
RASSF8CG5053 gene product from transcript CG5053-RA0.018
Klp68DKinesin-like protein at 68D0.018
nabCG33545 gene product from transcript CG33545-RC0.018
Ppt1Palmitoyl-protein thioesterase 10.017
Act5CActin 5C0.017
Snap25Synapse protein 250.017
lkb1CG9374 gene product from transcript CG9374-RJ0.016
RpS3Ribosomal protein S30.015
Akt1CG4006 gene product from transcript CG4006-RA0.015
msl-2male-specific lethal 20.015
CG5720CG5720 gene product from transcript CG5720-RA0.015
reporeversed polarity0.015
Syx1ASyntaxin 1A0.014
CG32528CG32528 gene product from transcript CG32528-RA0.014
PpcsPhosphopantothenoylcysteine synthetase0.014
CG8155CG8155 gene product from transcript CG8155-RA0.014
CG4030CG4030 gene product from transcript CG4030-RA0.014
dandistal antenna0.013
AdarAdenosine deaminase acting on RNA0.013
PtenCG5671 gene product from transcript CG5671-RB0.013
Mob4CG3403 gene product from transcript CG3403-RA0.013
C15CG7937 gene product from transcript CG7937-RA0.013
CG5568CG5568 gene product from transcript CG5568-RA0.013
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
dlx5adistal-less homeobox gene 5a0.013
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BCL2B-cell CLL/lymphoma 20.998
VEGFAvascular endothelial growth factor A0.959
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.839
EP300E1A binding protein p3000.814
BCL2L1BCL2-like 10.793
ESR1estrogen receptor 10.782
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.711
EGFRepidermal growth factor receptor0.663
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.623
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.598
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.566
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.555
HSPA8heat shock 70kDa protein 80.521
SOCS3suppressor of cytokine signaling 30.470
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.466
NR4A1nuclear receptor subfamily 4, group A, member 10.433
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.433
BADBCL2-associated agonist of cell death0.382
MAPTmicrotubule-associated protein tau0.372
CCL4chemokine (C-C motif) ligand 40.337
BCL2L11BCL2-like 11 (apoptosis facilitator)0.337
NONOnon-POU domain containing, octamer-binding0.318
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.317
CBX5chromobox homolog 50.294
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.275
CCR5chemokine (C-C motif) receptor 50.271
APLFaprataxin and PNKP like factor0.248
TP53BP2tumor protein p53 binding protein, 20.242
RPL18Aribosomal protein L18a0.232
PTPN1protein tyrosine phosphatase, non-receptor type 10.180
SOS1son of sevenless homolog 1 (Drosophila)0.168
XRCC4X-ray repair complementing defective repair in Chinese hamster cells 40.168
NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)0.162
KHDRBS1KH domain containing, RNA binding, signal transduction associated 10.156
VHLvon Hippel-Lindau tumor suppressor0.143
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.136
NOXA1NADPH oxidase activator 10.136
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.132
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.131
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.129
CCL5chemokine (C-C motif) ligand 50.124
FYNFYN oncogene related to SRC, FGR, YES0.121
RUNX1runt-related transcription factor 10.118
HSPD1heat shock 60kDa protein 1 (chaperonin)0.112
BIDBH3 interacting domain death agonist0.111
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.110
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.107
STAT5Asignal transducer and activator of transcription 5A0.102
CCL2chemokine (C-C motif) ligand 20.100
HDAC4histone deacetylase 40.096
NTRK1neurotrophic tyrosine kinase, receptor, type 10.096
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.094
NGFnerve growth factor (beta polypeptide)0.093
HSPA1Bheat shock 70kDa protein 1B0.091
IL8interleukin 80.090
GAS6growth arrest-specific 60.085
TEKTEK tyrosine kinase, endothelial0.078
BCORBCL6 corepressor0.076
NR4A3nuclear receptor subfamily 4, group A, member 30.076
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.075
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.074
PDZD11PDZ domain containing 110.074
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.073
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.072
PPIDpeptidylprolyl isomerase D0.072
CBX3chromobox homolog 30.072
FOSFBJ murine osteosarcoma viral oncogene homolog0.071
HDAC2histone deacetylase 20.071
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.070
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.070
BAXBCL2-associated X protein0.070
NRP1neuropilin 10.067
STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase0.066
CBX1chromobox homolog 10.063
CCL8chemokine (C-C motif) ligand 80.062
NFIL3nuclear factor, interleukin 3 regulated0.060
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.059
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.058
RPS6ribosomal protein S60.058
EPAS1endothelial PAS domain protein 10.058
HSPH1heat shock 105kDa/110kDa protein 10.058
PTGES3prostaglandin E synthase 3 (cytosolic)0.056
IDEinsulin-degrading enzyme0.056
NR4A2nuclear receptor subfamily 4, group A, member 20.055
IL6interleukin 6 (interferon, beta 2)0.055
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.054
SP1Sp1 transcription factor0.054
CREB1cAMP responsive element binding protein 10.053
CEBPDCCAAT/enhancer binding protein (C/EBP), delta0.053
NFKBIZnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta0.052
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.052
GRB2growth factor receptor-bound protein 20.051
MATKmegakaryocyte-associated tyrosine kinase0.051
ZNF746zinc finger protein 7460.050
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.050
RBBP4retinoblastoma binding protein 40.049
CXCL2chemokine (C-X-C motif) ligand 20.048
CASP3caspase 3, apoptosis-related cysteine peptidase0.048
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.997
Ptenphosphatase and tensin homolog0.939
Ntf3neurotrophin 30.938
Gria2glutamate receptor, ionotropic, AMPA2 (alpha 2)0.910
Pax3paired box gene 30.910
Retret proto-oncogene0.906
Bdnfbrain derived neurotrophic factor0.900
Ptgs2prostaglandin-endoperoxide synthase 20.869
Trp53transformation related protein 530.857
Emx1empty spiracles homolog 1 (Drosophila)0.856
Eya1eyes absent 1 homolog (Drosophila)0.850
Tgfbr1transforming growth factor, beta receptor I0.846
Vegfavascular endothelial growth factor A0.792
AxlAXL receptor tyrosine kinase0.779
Pax6paired box gene 60.720
Sox2SRY-box containing gene 20.700
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.659
Gabrb3gamma-aminobutyric acid (GABA) A receptor, subunit beta 30.658
Mt2metallothionein 20.621
Otx2orthodenticle homolog 2 (Drosophila)0.607
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.604
Mt1metallothionein 10.594
Isl1ISL1 transcription factor, LIM/homeodomain0.591
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.575
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.573
Nos3nitric oxide synthase 3, endothelial cell0.543
Pax2paired box gene 20.540
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.525
Gabrb2gamma-aminobutyric acid (GABA) A receptor, subunit beta 20.520
Ptpn11protein tyrosine phosphatase, non-receptor type 110.509
Nf1neurofibromatosis 10.499
FosFBJ osteosarcoma oncogene0.486
Sox10SRY-box containing gene 100.471
Plcg1phospholipase C, gamma 10.468
Foxf1aforkhead box F1a0.463
Vhlvon Hippel-Lindau tumor suppressor0.448
Grid1glutamate receptor, ionotropic, delta 10.446
Epas1endothelial PAS domain protein 10.443
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.437
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.421
Phox2apaired-like homeobox 2a0.413
Apoeapolipoprotein E0.408
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.408
Gdnfglial cell line derived neurotrophic factor0.405
Stx1asyntaxin 1A (brain)0.392
Cdk5r2cyclin-dependent kinase 5, regulatory subunit 2 (p39)0.391
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.390
Wt1Wilms tumor 1 homolog0.377
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.376
Dusp1dual specificity phosphatase 10.374
Rb1retinoblastoma 10.370
BaxBCL2-associated X protein0.363
Mdm2transformed mouse 3T3 cell double minute 20.354
Kcnj3potassium inwardly-rectifying channel, subfamily J, member 30.352
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.349
Tcfap2atranscription factor AP-2, alpha0.336
Chd7chromodomain helicase DNA binding protein 70.333
Nr3c1nuclear receptor subfamily 3, group C, member 10.322
Nrg1neuregulin 10.315
Nfe2l2nuclear factor, erythroid derived 2, like 20.307
Wdr26WD repeat domain 260.303
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.302
Fgfr1fibroblast growth factor receptor 10.301
Fgfr2fibroblast growth factor receptor 20.295
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.294
Klf6Kruppel-like factor 60.284
Lhx3LIM homeobox protein 30.283
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.283
Gria4glutamate receptor, ionotropic, AMPA4 (alpha 4)0.275
Adam12a disintegrin and metallopeptidase domain 12 (meltrin alpha)0.259
CblCasitas B-lineage lymphoma0.256
Phox2bpaired-like homeobox 2b0.254
Hif1ahypoxia inducible factor 1, alpha subunit0.254
Egr1early growth response 10.252
Lama5laminin, alpha 50.249
Tgfbr2transforming growth factor, beta receptor II0.247
Itgb1integrin beta 1 (fibronectin receptor beta)0.245
Rxraretinoid X receptor alpha0.244
Ror1receptor tyrosine kinase-like orphan receptor 10.243
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.243
Slc32a1solute carrier family 32 (GABA vesicular transporter), member 10.240
JunbJun-B oncogene0.240
Hand2heart and neural crest derivatives expressed transcript 20.237
Armcx3armadillo repeat containing, X-linked 30.231
Gad2glutamic acid decarboxylase 20.223
Adcyap1adenylate cyclase activating polypeptide 10.222
Kif5bkinesin family member 5B0.221
Pnpla2patatin-like phospholipase domain containing 20.214
Hoxd4homeobox D40.207
Hoxd13homeobox D130.204
Htr75-hydroxytryptamine (serotonin) receptor 70.202
Zfp36zinc finger protein 360.201
Acvr1activin A receptor, type 10.200
Adam17a disintegrin and metallopeptidase domain 170.200
Armcx2armadillo repeat containing, X-linked 20.199
Sim1single-minded homolog 1 (Drosophila)0.197
Rassf5Ras association (RalGDS/AF-6) domain family member 50.194
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Dusp1dual specificity phosphatase 10.851
Nr4a1nuclear receptor subfamily 4, group A, member 10.791
FosFBJ osteosarcoma oncogene0.763
Zfp36zinc finger protein 360.688
Nr4a3nuclear receptor subfamily 4, group A, member 30.461
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.433
Egr1early growth response 10.425
Hspa8heat shock protein 80.417
Ptafrplatelet-activating factor receptor0.366
St13suppression of tumorigenicity 130.354
Junbjun B proto-oncogene0.336
Errfi1ERBB receptor feedback inhibitor 10.278
Hsph1heat shock 105/110 protein 10.268
Stip1stress-induced phosphoprotein 10.265
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.260
Slc14a2solute carrier family 14 (urea transporter), member 20.244
Pebp1phosphatidylethanolamine binding protein 10.229
Socs3suppressor of cytokine signaling 30.182
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.177
Inpp5dinositol polyphosphate-5-phosphatase D0.171
Tbxas1thromboxane A synthase 1, platelet0.170
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.163
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.155
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.152
Eef2eukaryotic translation elongation factor 20.150
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.146
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.133
Prkcgprotein kinase C, gamma0.122
Nr4a2nuclear receptor subfamily 4, group A, member 20.118
Dnajb1DnaJ (Hsp40) homolog, subfamily B, member 10.116
Eno1enolase 1, (alpha)0.114
Gna12guanine nucleotide binding protein (G protein) alpha 120.111
Ddr1discoidin domain receptor tyrosine kinase 10.105
Fmnl1formin-like 10.100
Uhmk1U2AF homology motif (UHM) kinase 10.099
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.099
Insrinsulin receptor0.098
Klf4Kruppel-like factor 4 (gut)0.097
Hk1hexokinase 10.097
Ednrbendothelin receptor type B0.095
Pcm1pericentriolar material 10.094
Itgamintegrin, alpha M0.092
Pctk1PCTAIRE protein kinase 10.092
Ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.091
Nefmneurofilament, medium polypeptide0.090
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.085
Prkar2aprotein kinase, cAMP dependent regulatory, type II alpha0.078
Aldoaaldolase A, fructose-bisphosphate0.077
Gng7guanine nucleotide binding protein (G protein), gamma 70.077
Txnrd1thioredoxin reductase 10.076
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.072
Prkcdprotein kinase C, delta0.072
Unc5bunc-5 homolog B (C. elegans)0.071
Sirpasignal-regulatory protein alpha0.071
Atf2activating transcription factor 20.069
Hspa1aheat shock 70kD protein 1A0.069
Arl5aADP-ribosylation factor-like 5A0.068
Egr2early growth response 20.065
LOC681996similar to AHA1, activator of heat shock 90kDa protein ATPase homolog 10.065
Rhobras homolog gene family, member B0.064
Klf6Kruppel-like factor 60.064
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.063
Grm6glutamate receptor, metabotropic 60.062
Ccdc124coiled-coil domain containing 1240.061
Robo1roundabout homolog 1 (Drosophila)0.060
Cnga1cyclic nucleotide gated channel alpha 10.060
Dusp6dual specificity phosphatase 60.059
Pctk2PCTAIRE protein kinase 20.059
Cd38CD38 molecule0.056
Tpi1triosephosphate isomerase 10.056
Dusp5dual specificity phosphatase 50.056
Hckhemopoietic cell kinase0.055
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.053
Adrbk1adrenergic, beta, receptor kinase 10.053
Il1binterleukin 1 beta0.053
Homer2homer homolog 2 (Drosophila)0.052
Gclcglutamate-cysteine ligase, catalytic subunit0.052
Smad7SMAD family member 70.051
Casp3caspase 30.051
Impactimprinted and ancient0.051
Ptpn12protein tyrosine phosphatase, non-receptor type 120.050
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.050
Cishcytokine inducible SH2-containing protein0.049
Notch3Notch homolog 3 (Drosophila)0.049
Ptproprotein tyrosine phosphatase, receptor type, O0.048
Klf9Kruppel-like factor 90.048
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.047
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.046
Flt1FMS-related tyrosine kinase 10.046
Vav1vav 1 guanine nucleotide exchange factor0.045
Arcactivity-regulated cytoskeleton-associated protein0.045
Tcf4transcription factor 40.045
Ptgs2prostaglandin-endoperoxide synthase 20.044
Tmem69transmembrane protein 690.044
Syt7synaptotagmin VII0.044
Gria2glutamate receptor, ionotropic, AMPA 20.044
UgdhUDP-glucose dehydrogenase0.044
Marcksmyristoylated alanine rich protein kinase C substrate0.043
Mapk4mitogen-activated protein kinase 40.043
Bcl2l1Bcl2-like 10.043
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism