The network for 'macromolecular complex assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

macromolecular complex assembly

The aggregation, arrangement and bonding together of a set of macromolecules to form a complex.

NameDescriptionProbabilityFunc Analog Organism
cpbcapping protein beta0.976
hydhyperplastic discs0.975
KhcKinesin heavy chain0.927
aspabnormal spindle0.899
CaMKIICalcium/calmodulin-dependent protein kinase II0.869
SosSon of sevenless0.835
Cp190Centrosomal protein 190kD0.833
Klp10ACG1453 gene product from transcript CG1453-RA0.831
JIL-1CG6297 gene product from transcript CG6297-RA0.827
SNF1ASNF1A/AMP-activated protein kinase0.827
eIF-4EEukaryotic initiation factor 4E0.817
Cip4CG15015 gene product from transcript CG15015-RA0.809
par-6CG5884 gene product from transcript CG5884-RA0.806
ncdnon-claret disjunctional0.805
CycBCyclin B0.792
BicDBicaudal D0.782
dlg1discs large 10.776
IncenpInner centromere protein0.775
Ras85DRas oncogene at 85D0.749
Arp66BActin-related protein 66B0.730
shotshort stop0.722
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.718
MadMothers against dpp0.711
MicalMolecule interacting with CasL0.674
Fs(2)KetFemale sterile (2) Ketel0.668
Hsp27Heat shock protein 270.657
par-1CG8201 gene product from transcript CG8201-RA0.649
CG4680CG4680 gene product from transcript CG4680-RA0.642
CycACyclin A0.642
MRG15CG6363 gene product from transcript CG6363-RA0.639
CycECyclin E0.637
mspsmini spindles0.636
Snr1Snf5-related 10.635
Pink1PTEN-induced putative kinase 10.633
Cdc42CG12530 gene product from transcript CG12530-RA0.623
Arc-p34CG10954 gene product from transcript CG10954-RA0.619
G-oalpha47AG protein oalpha 47A0.614
CtBPC-terminal Binding Protein0.608
Pros26.4Proteasome 26S subunit subunit 4 ATPase0.599
CG10267CG10267 gene product from transcript CG10267-RB0.598
Nup154Nucleoporin 1540.592
BRWD3CG31132 gene product from transcript CG31132-RA0.592
Vps35Vacuolar protein sorting 350.579
marsCG17064 gene product from transcript CG17064-RB0.563
tacctransforming acidic coiled-coil protein0.554
larpLa related protein0.554
wacwee Augmin0.551
wupAwings up A0.534
Mcm5Minichromosome maintenance 50.508
AblAbl tyrosine kinase0.503
CctgammaCG8977 gene product from transcript CG8977-RC0.501
Fas2Fasciclin 20.496
htshu li tai shao0.479
HLHm7E(spl) region transcript m70.477
S6kRPS6-p70-protein kinase0.476
E(spl)Enhancer of split0.475
Taf1TBP-associated factor 10.473
Rpt1CG1341 gene product from transcript CG1341-RA0.454
Su(var)205Suppressor of variegation 2050.449
MarfMitochondrial assembly regulatory factor0.446
RhoGEF2CG9635 gene product from transcript CG9635-RF0.440
Mov34CG3416 gene product from transcript CG3416-RA0.435
HmgDHigh mobility group protein D0.434
sleslender lobes0.433
ovoCG6824 gene product from transcript CG6824-RE0.424
BubR1Bub1-related kinase0.422
His2AvHistone H2A variant0.421
Pp2A-29BProtein phosphatase 2A at 29B0.414
ftz-f1ftz transcription factor 10.413
Klp3AKinesin-like protein at 3A0.406
betaTub56Dbeta-Tubulin at 56D0.400
spd-2spindle defective 20.399
CG5174CG5174 gene product from transcript CG5174-RM0.398
EphrinCG1862 gene product from transcript CG1862-RA0.382
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
atn-1Protein ATN-10.419
rpt-5Protein RPT-50.351
lmn-1Protein LMN-10.292
pqn-59Protein PQN-590.289
hcp-3Protein HCP-30.263
acs-4Protein ACS-40.244
lin-36Protein LIN-360.244
deb-1Protein DEB-10.241
mat-3Protein MAT-30.228
ret-1Protein RET-10.214
pkg-1Protein PKG-10.210
mrt-2Protein MRT-20.209
cks-1Protein CKS-10.196
snr-5Protein SNR-50.195
F11D5.1Protein F11D5.10.191
plp-1Protein PLP-10.191
C53B4.4Protein C53B4.40.190
ubc-12Protein UBC-120.190
tag-232Protein TAG-2320.188
lin-24Protein LIN-240.188
let-858Protein LET-8580.181
act-4Protein ACT-40.180
aap-1Protein AAP-10.178
dpf-3Protein DPF-30.177
ulp-1Protein ULP-10.175
tag-260Protein TAG-2600.174
rpn-12Protein RPN-120.173
CELE_C39E9.12Protein C39E9.120.173
hlh-2Protein HLH-20.170
unc-40Protein UNC-400.168
D1081.8Protein D1081.80.168
ZC395.10Protein ZC395.100.167
his-1Protein HIS-10.163
eat-6Protein EAT-60.162
mig-2Protein MIG-20.162
unc-54Protein UNC-540.160
nud-1Protein NUD-10.159
R90.1Protein R90.10.159
lin-53Protein LIN-530.155
C56G2.7Protein C56G2.70.155
pha-4Protein PHA-40.154
tag-163Protein TAG-1630.153
CELE_C24H12.4Protein C24H12.40.151
T02H6.1Protein T02H6.10.149
mcm-2Protein MCM-20.149
F39G3.5Protein F39G3.50.149
dpy-30Protein DPY-300.148
mpk-1Protein MPK-10.148
unc-112Protein UNC-1120.147
spd-5Protein SPD-50.147
lst-1Protein LST-10.147
mag-1Protein MAG-10.146
kle-2Protein KLE-20.146
rpb-2Protein RPB-20.145
otub-1Protein OTUB-10.145
dlc-1Protein DLC-10.142
mcm-6Protein MCM-60.141
CELE_Y75B8A.25Protein Y75B8A.250.141
hsp-1Protein HSP-10.141
cct-1Protein CCT-10.141
pas-4Protein PAS-40.139
npp-9Protein NPP-90.139
nmy-2Protein NMY-20.139
nol-5Protein NOL-50.139
prx-5Protein PRX-50.138
prp-8Protein PRP-80.138
gsy-1Protein GSY-10.137
smc-3Protein SMC-30.136
dsh-2Protein DSH-20.136
uba-1Protein UBA-10.136
npl-4.2Protein NPL-4.20.135
CELE_B0334.4Protein B0334.40.135
K01G5.5Protein K01G5.50.133
nhr-2Protein NHR-20.133
zyg-9Protein ZYG-90.132
T24H10.1Protein T24H10.10.132
deps-1Protein DEPS-10.131
rpn-8Protein RPN-80.131
spc-1Protein SPC-10.130
twk-18Protein TWK-180.128
unc-53Protein UNC-530.128
F56D2.6Protein F56D2.60.124
spd-2Protein SPD-20.123
klp-16Protein KLP-160.123
his-64Protein HIS-640.123
fbxa-108Protein FBXA-1080.122
egl-44Protein EGL-440.122
T24F1.2Protein T24F1.20.121
W02B12.10Protein W02B12.100.121
vab-8Protein VAB-80.121
let-418Protein LET-4180.120
pas-1Protein PAS-10.120
xpo-2Protein XPO-20.120
tars-1Protein TARS-10.120
sun-1Protein SUN-10.119
klp-7Protein KLP-70.119
zyg-1Protein ZYG-10.118
vab-3Protein VAB-30.118
cap-2Protein CAP-20.117
unc-9Protein UNC-90.117
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
lama4laminin, alpha 40.370
mef2dmyocyte enhancer factor 2d0.348
tjp1tight junction protein 1 (zona occludens 1)0.305
gpiaglucose phosphate isomerase a0.301
setbSET translocation (myeloid leukemia-associated) B0.289
pabpc1apoly A binding protein, cytoplasmic 1 a0.247
rpa1replication protein A10.227
arpc5aactin related protein 2/3 complex, subunit 5A0.211
ccm2cerebral cavernous malformation 20.210
srfserum response factor0.209
nup107nucleoporin 1070.204
psma8proteasome (prosome, macropain) subunit, alpha type, 80.197
ranras-related nuclear protein0.192
nsfaN-ethylmaleimide-sensitive factor a0.189
tnni2a.4troponin I, skeletal, fast 2a.40.189
bmp4bone morphogenetic protein 40.188
alas2aminolevulinate, delta-, synthetase 20.187
nop58NOP58 ribonucleoprotein homolog (yeast)0.173
msh6mutS homolog 6 (E. coli)0.173
cdh2cadherin 2, neuronal0.168
robo2roundabout homolog 20.162
prpf8pre-mRNA processing factor 80.161
cct7chaperonin containing TCP1, subunit 7 (eta)0.159
sass6spindle assembly 6 homolog (C. elegans)0.152
aldocbaldolase C, fructose-bisphosphate, b0.150
cotl1coactosin-like 1 (Dictyostelium)0.146
snrnp70small nuclear ribonucleoprotein 70 (U1)0.138
ikzf1IKAROS family zinc finger 1 (Ikaros)0.137
nusap1nucleolar and spindle associated protein 10.132
tnnt3btroponin T3b, skeletal, fast0.126
myf6myogenic factor 60.125
sptbspectrin, beta, erythrocytic0.124
plxnb2aplexin b2a0.124
atp1a3aATPase, Na+/K+ transporting, alpha 3a polypeptide0.124
psma1proteasome (prosome, macropain) subunit, alpha type, 10.122
dusp6dual specificity phosphatase 60.121
slc39a7solute carrier family 39 (zinc transporter), member 70.119
caspacaspase a0.116
rplp0ribosomal protein, large, P00.114
tnnt2atroponin T2a, cardiac0.112
cx43connexin 430.112
tp53tumor protein p530.111
pkd2polycystic kidney disease 20.109
hsp90a.2heat shock protein 90-alpha 20.108
vegfcvascular endothelial growth factor c0.105
capza1bcapping protein (actin filament) muscle Z-line, alpha 1b0.100
ttnatitin a0.099
pwp2hPWP2 periodic tryptophan protein homolog (yeast)0.096
hnf4ahepatocyte nuclear factor 4, alpha0.095
ddx18DEAD (Asp-Glu-Ala-Asp) box polypeptide 180.095
mgaMAX gene associated0.095
slc4a1asolute carrier family 4, anion exchanger, member 1a0.094
hnrplheterogeneous nuclear ribonucleoprotein L0.093
cdc42cell division cycle 420.093
eif4a1beukaryotic translation initiation factor 4A, isoform 1B0.092
plk1polo-like kinase 1 (Drosophila)0.092
atp1a3bATPase, Na+/K+ transporting, alpha 3b polypeptide0.091
psmb3proteasome (prosome, macropain) subunit, beta type, 30.089
fabp3fatty acid binding protein 3, muscle and heart0.088
vcpvalosin containing protein0.088
ncor1nuclear receptor co-repressor 10.085
anxa2aannexin A2a0.084
nup88nucleoporin 880.083
esco2establishment of cohesion 1 homolog 20.082
sgcdsarcoglycan, delta (dystrophin-associated glycoprotein)0.082
nxph1neurexophilin 10.081
mllt11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 110.081
dnmt1DNA (cytosine-5-)-methyltransferase 10.080
ahctf1AT hook containing transcription factor 10.080
hsp90a.1heat shock protein 90-alpha 10.078
myhz1.2myosin, heavy polypeptide 1.2, skeletal muscle0.078
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.078
eomesaeomesodermin homolog a0.078
igfbp1binsulin-like growth factor binding protein 1b0.076
eif5a2eukaryotic translation initiation factor 5A20.075
ddx46DEAD (Asp-Glu-Ala-Asp) box polypeptide 460.075
ptch2patched 20.074
gro1groucho 10.074
cct3chaperonin containing TCP1, subunit 3 (gamma)0.074
eno3enolase 3, (beta, muscle)0.074
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.074
brd4bromodomain containing 40.073
naspnuclear autoantigenic sperm protein (histone-binding)0.073
rbl1retinoblastoma-like 1 (p107)0.072
fbxw4F-box and WD-40 domain protein 40.072
sulf2sulfatase 20.071
nup93nucleoporin 930.070
eml2echinoderm microtubule associated protein like 20.069
anp32aacidic (leucine-rich) nuclear phosphoprotein 32 family, member A0.069
nap1l1nucleosome assembly protein 1, like 10.069
sod1superoxide dismutase 1, soluble0.068
dtldenticleless homolog (Drosophila)0.068
pbx4pre-B-cell leukemia transcription factor 40.067
chd7chromodomain helicase DNA binding protein 70.067
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.741
Mmp7matrix metallopeptidase 70.712
Olfm1olfactomedin 10.659
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.632
Sirpasignal-regulatory protein alpha0.621
Avpr1barginine vasopressin receptor 1B0.609
Alas2aminolevulinate, delta-, synthase 20.562
Hsp90b1heat shock protein 90, beta, member 10.561
Vamp1vesicle-associated membrane protein 10.555
Rhoaras homolog gene family, member A0.547
Hbbhemoglobin, beta0.530
Actr3ARP3 actin-related protein 3 homolog (yeast)0.528
Mapre1microtubule-associated protein, RP/EB family, member 10.518
Ap2b1adaptor-related protein complex 2, beta 1 subunit0.513
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.511
Cd74Cd74 molecule, major histocompatibility complex, class II invariant chain0.510
Exoc5exocyst complex component 50.486
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.471
St13suppression of tumorigenicity 130.468
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.463
Tmed2transmembrane emp24 domain trafficking protein 20.429
Anxa2annexin A20.418
Neflneurofilament, light polypeptide0.407
Leprleptin receptor0.405
Col1a1collagen, type I, alpha 10.404
Pygmphosphorylase, glycogen, muscle0.404
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.401
Trim23tripartite motif-containing 230.390
Col3a1collagen, type III, alpha 10.388
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.386
RT1-Db1RT1 class II, locus Db10.384
Arpc2actin related protein 2/3 complex, subunit 20.377
RT1-BbRT1 class II, locus Bb0.376
Myh3myosin, heavy chain 3, skeletal muscle, embryonic0.372
Metmet proto-oncogene0.359
Efhd2EF-hand domain family, member D20.357
Dlg4discs, large homolog 4 (Drosophila)0.356
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.354
Vav1vav 1 guanine nucleotide exchange factor0.352
Jak1Janus kinase 10.351
Jak2Janus kinase 20.350
Map1amicrotubule-associated protein 1A0.348
Gad2glutamate decarboxylase 20.344
Snap25synaptosomal-associated protein 250.344
Acadlacyl-Coenzyme A dehydrogenase, long-chain0.342
Casp2caspase 20.339
Rab7aRAB7A, member RAS oncogene family0.339
Cd80Cd80 molecule0.339
Gnb2l1guanine nucleotide binding protein (G protein), beta polypeptide 2 like 10.338
Pak3p21 protein (Cdc42/Rac)-activated kinase 30.338
Pak2p21 protein (Cdc42/Rac)-activated kinase 20.336
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.334
St8sia3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 30.332
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.332
Camk2bcalcium/calmodulin-dependent protein kinase II beta0.322
Atp7bATPase, Cu++ transporting, beta polypeptide0.322
Gng7guanine nucleotide binding protein (G protein), gamma 70.318
Rpl4ribosomal protein L40.318
Hnrnpfheterogeneous nuclear ribonucleoprotein F0.317
Mylk2myosin light chain kinase 20.316
Scamp2secretory carrier membrane protein 20.316
LOC100134871beta globin minor gene0.313
Anxa5annexin A50.313
Chrnecholinergic receptor, nicotinic, epsilon0.311
Taok1TAO kinase 10.310
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.310
Plrg1pleiotropic regulator 1, PRL1 homolog (Arabidopsis)0.309
Cdc42cell division cycle 42 (GTP binding protein)0.308
Gipgastric inhibitory polypeptide0.307
Stip1stress-induced phosphoprotein 10.307
Reg3gregenerating islet-derived 3 gamma0.307
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.307
S1pr2sphingosine-1-phosphate receptor 20.306
Mapk1mitogen activated protein kinase 10.304
LOC287167globin, alpha0.303
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.300
Gnao1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.298
Hba-a2hemoglobin alpha, adult chain 20.297
Grin1glutamate receptor, ionotropic, N-methyl D-aspartate 10.294
Lbplipopolysaccharide binding protein0.294
Rab20RAB20, member RAS oncogene family0.293
Apba3amyloid beta (A4) precursor protein-binding, family A, member 30.293
Smad7SMAD family member 70.292
Pttg1pituitary tumor-transforming 10.292
Cfl1cofilin 1, non-muscle0.286
Hspd1heat shock protein 1 (chaperonin)0.282
Tagln2transgelin 20.280
Wbp11WW domain binding protein 110.278
RT1-BaRT1 class II, locus Ba0.273
Cxcl10chemokine (C-X-C motif) ligand 100.272
Pdk4pyruvate dehydrogenase kinase, isozyme 40.272
Scn5asodium channel, voltage-gated, type V, alpha subunit0.272
Psmb4proteasome (prosome, macropain) subunit, beta type 40.271
Trhr2thyrotropin releasing hormone receptor 20.269
Lig3ligase III, DNA, ATP-dependent0.269
Casp3caspase 30.268
Lyz2lysozyme 20.268
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism