IMP: Integrative Multi-species Prediction

The network for 'meiotic dna double strand break formation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

meiotic dna double strand break formation

The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination.

Drosophila melanogaster

Name	Description	Probability
CG7239	CG7239 gene product from transcript CG7239-RA	0.602
CG10107	CG10107 gene product from transcript CG10107-RA	0.388
prod	proliferation disrupter	0.357
CG11560	CG11560 gene product from transcript CG11560-RA	0.282
CG14711	CG14711 gene product from transcript CG14711-RA	0.243
CG7183	CG7183 gene product from transcript CG7183-RA	0.223
CG7928	CG7928 gene product from transcript CG7928-RA	0.222
CG4813	CG4813 gene product from transcript CG4813-RA	0.127
CG4282	CG4282 gene product from transcript CG4282-RA	0.118
CG7357	CG7357 gene product from transcript CG7357-RA	0.088
CG16941	CG16941 gene product from transcript CG16941-RA	0.071
l(1)G0095	lethal (1) G0095	0.069
CG2617	CG2617 gene product from transcript CG2617-RA	0.068
Hlc	Helicase	0.068
CG11403	CG11403 gene product from transcript CG11403-RA	0.063
CG15107	CG15107 gene product from transcript CG15107-RA	0.062
DMAP1	CG11132 gene product from transcript CG11132-RA	0.062
trem	trade embargo	0.060
CG11696	CG11696 gene product from transcript CG11696-RA	0.058
CG4424	CG4424 gene product from transcript CG4424-RA	0.057
CG2662	CG2662 gene product from transcript CG2662-RA	0.052
MBD-like	CG8208 gene product from transcript CG8208-RA	0.052
Adf1	Adh transcription factor 1	0.048
CG14667	CG14667 gene product from transcript CG14667-RA	0.047
CG16812	CG16812 gene product from transcript CG16812-RA	0.040
CG6985	CG6985 gene product from transcript CG6985-RA	0.039
Cdk9	Cyclin-dependent kinase 9	0.038
CG10366	CG10366 gene product from transcript CG10366-RA	0.034
CG10267	CG10267 gene product from transcript CG10267-RB	0.034
CG15601	CG15601 gene product from transcript CG15601-RA	0.033
CG17568	CG17568 gene product from transcript CG17568-RA	0.033
CG15436	CG15436 gene product from transcript CG15436-RA	0.033
l(2)05714	lethal (2) 05714	0.032
CG14814	CG14814 gene product from transcript CG14814-RA	0.030
CG5199	CG5199 gene product from transcript CG5199-RA	0.030
CG6506	CG6506 gene product from transcript CG6506-RA	0.029
DNApol-delta	DNA-polymerase-delta	0.029
CG5180	CG5180 gene product from transcript CG5180-RB	0.028
CG11307	CG11307 gene product from transcript CG11307-RA	0.028
SMC1	CG6057 gene product from transcript CG6057-RA	0.026
CG1024	CG1024 gene product from transcript CG1024-RB	0.024
CG2712	CG2712 gene product from transcript CG2712-RA	0.024
A16	CG9933 gene product from transcript CG9933-RA	0.024
enok	enoki mushroom	0.023
Slu7	CG1420 gene product from transcript CG1420-RA	0.022
CG6418	CG6418 gene product from transcript CG6418-RB	0.022
Taf7	TBP-associated factor 7	0.022
RhoGEF4	CG8606 gene product from transcript CG8606-RA	0.021
atms	antimeros	0.020
az2	CG1605 gene product from transcript CG1605-RA	0.020
CG3995	CG3995 gene product from transcript CG3995-RA	0.020
CG5872	CG5872 gene product from transcript CG5872-RA	0.020
CG17361	CG17361 gene product from transcript CG17361-RA	0.020
CG7609	CG7609 gene product from transcript CG7609-RB	0.019
CG13367	CG13367 gene product from transcript CG13367-RA	0.019
CG11504	CG11504 gene product from transcript CG11504-RB	0.019
Gem2	Gemin2	0.019
YL-1	CG4621 gene product from transcript CG4621-RA	0.019
CG14074	CG14074 gene product from transcript CG14074-RA	0.018
Tfb1	CG8151 gene product from transcript CG8151-RB	0.018
Actr13E	Actin-related protein 13E	0.018
Orc6	Origin recognition complex subunit 6	0.018
Ripalpha	RPA-interacting protein alpha	0.018
Taf8	TBP-associated factor 8	0.018
CG9996	CG9996 gene product from transcript CG9996-RB	0.018
CG8319	CG8319 gene product from transcript CG8319-RA	0.018
jigr1	jing interacting gene regulatory 1	0.018
CG1792	CG1792 gene product from transcript CG1792-RA	0.017
CG9797	CG9797 gene product from transcript CG9797-RA	0.017
CG9839	CG9839 gene product from transcript CG9839-RA	0.017
CG4709	CG4709 gene product from transcript CG4709-RA	0.017
fs(2)ltoPP43	female sterile (2) ltoPP43	0.017
Git	CG16728 gene product from transcript CG16728-RA	0.016
Gsc	Goosecoid	0.016
Sgf29	CG30390 gene product from transcript CG30390-RA	0.016
RfC4	Replication factor C subunit 4	0.015
CG12972	CG12972 gene product from transcript CG12972-RA	0.015
CG17806	CG17806 gene product from transcript CG17806-RA	0.015
Bub3	CG7581 gene product from transcript CG7581-RA	0.015
Pp4-19C	Protein phosphatase 19C	0.015
CG13344	CG13344 gene product from transcript CG13344-RA	0.015
Rab4	Rab-protein 4	0.015
CG8478	CG8478 gene product from transcript CG8478-RD	0.015
bl	bancal	0.014
CG14220	CG14220 gene product from transcript CG14220-RA	0.014
MED31	Mediator complex subunit 31	0.014
Mfap1	Microfibril-associated protein 1	0.014
Ptp61F	Protein tyrosine phosphatase 61F	0.014
CG9775	CG9775 gene product from transcript CG9775-RA	0.014
CG5491	CG5491 gene product from transcript CG5491-RA	0.014
CG1621	CG1621 gene product from transcript CG1621-RA	0.013
CG2129	CG2129 gene product from transcript CG2129-RA	0.013
ari-2	ariadne 2	0.013
CG4730	CG4730 gene product from transcript CG4730-RA	0.013
CG4854	CG4854 gene product from transcript CG4854-RA	0.013
CG17802	CG17802 gene product from transcript CG17802-RA	0.012
CG8301	CG8301 gene product from transcript CG8301-RA	0.012
CG17446	CG17446 gene product from transcript CG17446-RB	0.012
CG3032	CG3032 gene product from transcript CG3032-RA	0.012
CG7745	CG7745 gene product from transcript CG7745-RA	0.012

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Caenorhabditis elegans

Name	Description	Probability
F30A10.3	Protein F30A10.3	0.023
B0205.1	Protein B0205.1	0.021
F10E7.11	Protein F10E7.11	0.020
T05F1.2	Protein T05F1.2	0.020
C13G5.2	Protein C13G5.2	0.018
Y5F2A.4	Protein Y5F2A.4	0.016
clec-87	Protein CLEC-87	0.014
tag-342	Protein TAG-342	0.014
hmg-12	Protein HMG-12	0.014
C02B10.4	Protein C02B10.4	0.013
CELE_F01D4.5	Protein F01D4.5	0.013
lin-61	Protein LIN-61	0.013
cpg-4	Protein CPG-4	0.013
F30F8.1	Protein F30F8.1	0.012
tbp-1	Protein TBP-1	0.012
ima-2	Protein IMA-2	0.011
F26H11.4	Protein F26H11.4	0.011
npp-18	Protein NPP-18	0.011
F37A4.1	Protein F37A4.1	0.010
hcf-1	Protein HCF-1	0.010
F08G5.1	Protein F08G5.1	0.010
CELE_Y57G11C.9	Protein Y57G11C.9	0.010

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Danio rerio

Name	Description	Probability	Func Analog Organism

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Homo sapiens

Name	Description	Probability	Func Analog Organism

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Mus musculus

Name	Description	Probability
Hells	helicase, lymphoid specific	0.031
Plk4	polo-like kinase 4 (Drosophila)	0.027
Trim59	tripartite motif-containing 59	0.013
Smc4	structural maintenance of chromosomes 4	0.011

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Rattus norvegicus

Name	Description	Probability	Func Analog Organism

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Saccharomyces cerevisiae

Name	Description	Probability
SMC4	Smc4p	0.091
YCG1	Ycg1p	0.062
RAD9	Rad9p	0.058
BRN1	Brn1p	0.045
HDA2	Hda2p	0.028
PEX12	Pex12p	0.028
RAD50	Rad50p	0.022
SMC2	Smc2p	0.021
MSH4	Msh4p	0.021
RAD53	Rad53p	0.020
MAM1	Mam1p	0.020
REV1	Rev1p	0.020
RAT1	Rat1p	0.018
SRD1	Srd1p	0.018
ECM11	Ecm11p	0.018
PDS1	Pds1p	0.017
MMS1	Mms1p	0.017
PEX22	Pex22p	0.016
YLR264C-A	hypothetical protein	0.016
VIK1	Vik1p	0.016
HO	Hop	0.016
SHU1	Shu1p	0.016
HXT3	Hxt3p	0.016
PRI1	Pri1p	0.016
YOL038C-A	hypothetical protein	0.016
RED1	Red1p	0.015
TOF2	Tof2p	0.015
MER1	Mer1p	0.015
REC114	Rec114p	0.015
LEU2	Leu2p	0.015
YCS4	Ycs4p	0.015
GYL1	Gyl1p	0.014
ZPS1	Zps1p	0.014
CHA1	Cha1p	0.014
YLR162W	hypothetical protein	0.014
SAE2	Sae2p	0.014
MSH5	Msh5p	0.014
URA3	Ura3p	0.013
LRS4	Lrs4p	0.013
YPR157W	hypothetical protein	0.013
YAR068W	hypothetical protein	0.013
SPL2	Spl2p	0.013
YBL044W	hypothetical protein	0.013
YLR042C	hypothetical protein	0.013
YIL151C	hypothetical protein	0.013
YBR013C	hypothetical protein	0.013
ADH2	Adh2p	0.013
IZH4	Izh4p	0.012
ATP6	Atp6p	0.012
ZIP1	Zip1p	0.012
ALT2	Alt2p	0.012
HPF1	Hpf1p	0.012
ARP10	Arp10p	0.012
DBF4	Dbf4p	0.012
YOL013W-A	hypothetical protein	0.012
COS12	Cos12p	0.012
FMT1	Fmt1p	0.012
AUA1	Aua1p	0.012
OPT2	Opt2p	0.012
MYO4	Myo4p	0.011
SWM2	Swm2p	0.011
GEA2	Gea2p	0.011
YIR035C	hypothetical protein	0.011
YPR096C	hypothetical protein	0.011
MF(ALPHA)2	Mf(alpha)2p	0.011
YKR075C	hypothetical protein	0.011
VPS9	Vps9p	0.011
NRG2	Nrg2p	0.011
SCM4	Scm4p	0.011
CRP1	Crp1p	0.011
ARG8	Arg8p	0.011
YOR365C	hypothetical protein	0.011
UPS3	Ups3p	0.011
REC104	Rec104p	0.011
RAD24	Rad24p	0.011
MFA2	Mfa2p	0.011
YCR050C	hypothetical protein	0.011
UBA2	Uba2p	0.011
DIC1	Dic1p	0.011
SAE3	Sae3p	0.011
BSC1	Bsc1p	0.011
MCX1	Mcx1p	0.011
BNA4	Bna4p	0.011
MMS4	Mms4p	0.011
CPD1	Cpd1p	0.010
SWC7	Swc7p	0.010
PRS2	Prs2p	0.010
HOP2	Hop2p	0.010
NUP157	Nup157p	0.010
GPX2	Gpx2p	0.010
MUM3	Mum3p	0.010
CUP1-1	Cup1-1p	0.010
MEK1	Mek1p	0.010
BDS1	Bds1p	0.010
CST9	Cst9p	0.010
YAL037C-A	hypothetical protein	0.010
NUT2	Nut2p	0.010
YAR066W	hypothetical protein	0.010
YGR035C	hypothetical protein	0.010
MRC1	Mrc1p	0.010