The network for 'regulation of myeloid leukocyte differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of myeloid leukocyte differentiation

Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
mpxmyeloid-specific peroxidase0.991
junbljun B proto-oncogene, like0.648
nf1aneurofibromin 1a0.614
lcp1lymphocyte cytosolic plastin 10.559
tal1T-cell acute lymphocytic leukemia 10.528
cmybtranscription factor cmyb0.449
rag1recombination activating gene 10.322
csf1racolony stimulating factor 1 receptor, a0.322
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.285
lyzlysozyme0.272
spi1lspleen focus forming virus (SFFV) proviral integration oncogene spi1 like0.239
drldraculin0.221
LOC100331484hypothetical protein LOC1003314840.172
ltkleukocyte tyrosine kinase0.155
kitakit receptor a0.124
sc:d812sc:d8120.121
foxi3aforkhead box I3a0.094
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.090
runx1runt-related transcription factor 10.061
smyhc1slow myosin heavy chain 10.061
gata1aGATA binding protein 1a0.061
wnt8awingless-type MMTV integration site family, member 8a0.058
trim71tripartite motif-containing 710.050
csf3rcolony stimulating factor 3 receptor (granulocyte)0.046
tfap2etranscription factor AP-2 epsilon0.045
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.044
LOC560602novel protein similar to vertebrate solute carrier family 2 (facilitated glucose transporter), member 6 (SLC2A6)0.043
mychmyelocytomatosis oncogene homolog0.039
atp6v0d1ATPase, H+ transporting, V0 subunit D isoform 10.039
rargaretinoic acid receptor gamma a0.038
mmp13amatrix metalloproteinase 13a0.037
lmo2LIM domain only 2 (rhombotin-like 1)0.035
slc24a5solute carrier family 24, member 50.034
col12a1collagen, type XII, alpha 10.033
gadd45bagrowth arrest and DNA-damage-inducible, beta a0.032
lmo4aLIM domain only 4a0.028
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.028
irf8interferon regulatory factor 80.028
kcnj13potassium inwardly-rectifying channel, subfamily J, member 130.027
rarabretinoic acid receptor, alpha b0.026
atf3activating transcription factor 30.024
nf1bneurofibromin 1b0.024
etv2ets variant gene 20.024
mcoln1mucolipin 10.023
egfl7EGF-like-domain, multiple 70.023
mmp14amatrix metalloproteinase 14a (membrane-inserted)0.022
socs3asuppressor of cytokine signaling 3a0.022
efnb2aephrin B2a0.021
bcl2l10BCL2-like 10 (apoptosis facilitator)0.019
vps39vacuolar protein sorting 39 homolog (S. cerevisiae)0.019
clic2chloride intracellular channel 20.018
mlphbmelanophilin b0.018
f2rcoagulation factor II (thrombin) receptor0.018
si:rp71-39b20.7si:rp71-39b20.70.017
btg1B-cell translocation gene 10.017
trpm7transient receptor potential cation channel, subfamily M, member 70.017
junbjun B proto-oncogene0.017
cpoxcoproporphyrinogen oxidase0.016
anxa11aannexin A11a0.016
bnc2basonuclin 20.016
mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.016
zgc:112329zgc:1123290.015
tyrp1tyrosinase-related protein 10.015
ednrb1endothelin receptor B0.015
tgfbitransforming growth factor, beta-induced0.014
mmp9matrix metalloproteinase 90.014
zgc:162329zgc:1623290.013
tob1atransducer of ERBB2, 1a0.013
celf1cugbp, Elav-like family member 10.013
mef2cbmyocyte enhancer factor 2cb0.013
tlr3toll-like receptor 30.012
pdcd2programmed cell death 20.012
comtacatechol-O-methyltransferase a0.012
cd247lCD247 antigen like0.012
jazf1bJAZF zinc finger 1b0.012
ca15acarbonic anhydrase XV a0.012
wu:fb80a07wu:fb80a070.012
bcl2B-cell leukemia/lymphoma 20.012
tgfb3transforming growth factor, beta 30.011
LOC100151531zinc finger protein Gfi-1b-like0.011
adora2aaadenosine A2a receptor a0.011
atp6v1hATPase, H+ transporting, lysosomal, V1 subunit H0.011
fgf17fibroblast growth factor 170.010
cdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)0.010
slc2a13solute carrier family 2 (facilitated glucose transporter), member 130.010
safbscaffold attachment factor B0.010
rykreceptor-like tyrosine kinase0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CASP8caspase 8, apoptosis-related cysteine peptidase0.991
C1QAcomplement component 1, q subcomponent, A chain0.980
CCR5chemokine (C-C motif) receptor 50.978
ZNF43zinc finger protein 430.938
BIRC3baculoviral IAP repeat containing 30.894
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.876
IL4Rinterleukin 4 receptor0.871
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.868
CCL5chemokine (C-C motif) ligand 50.831
RIPK2receptor-interacting serine-threonine kinase 20.808
CXCL9chemokine (C-X-C motif) ligand 90.799
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.779
CFLARCASP8 and FADD-like apoptosis regulator0.777
CXCL10chemokine (C-X-C motif) ligand 100.764
PTPN6protein tyrosine phosphatase, non-receptor type 60.744
HOXB5homeobox B50.695
CXCL2chemokine (C-X-C motif) ligand 20.675
CCL4chemokine (C-C motif) ligand 40.671
LILRB3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.646
ZNF253zinc finger protein 2530.644
CD40CD40 molecule, TNF receptor superfamily member 50.625
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.608
IFNGinterferon, gamma0.594
SH2D4ASH2 domain containing 4A0.564
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.546
IL8interleukin 80.526
FASLGFas ligand (TNF superfamily, member 6)0.498
CCR1chemokine (C-C motif) receptor 10.493
FASFas (TNF receptor superfamily, member 6)0.481
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.474
JUNDjun D proto-oncogene0.470
TRAF1TNF receptor-associated factor 10.453
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.435
JUNjun proto-oncogene0.432
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.417
CXCL11chemokine (C-X-C motif) ligand 110.412
ZNF273zinc finger protein 2730.397
CREBBPCREB binding protein0.380
IRF4interferon regulatory factor 40.376
CCL22chemokine (C-C motif) ligand 220.376
ZNF430zinc finger protein 4300.375
RXRAretinoid X receptor, alpha0.340
CCL8chemokine (C-C motif) ligand 80.340
IL1Binterleukin 1, beta0.339
HOXA10homeobox A100.339
IL2RBinterleukin 2 receptor, beta0.330
PILRApaired immunoglobin-like type 2 receptor alpha0.319
ZNF675zinc finger protein 6750.317
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.313
HOXA5homeobox A50.306
MDM2Mdm2 p53 binding protein homolog (mouse)0.302
CCR7chemokine (C-C motif) receptor 70.291
BIRC2baculoviral IAP repeat containing 20.288
CXCL5chemokine (C-X-C motif) ligand 50.278
CCR4chemokine (C-C motif) receptor 40.277
ZNF708zinc finger protein 7080.276
CCR2chemokine (C-C motif) receptor 20.272
SH3BP2SH3-domain binding protein 20.268
ZNF93zinc finger protein 930.244
HCKhemopoietic cell kinase0.242
JUPjunction plakoglobin0.229
ZNF91zinc finger protein 910.228
SOCS3suppressor of cytokine signaling 30.227
CASP3caspase 3, apoptosis-related cysteine peptidase0.212
EPORerythropoietin receptor0.209
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.207
IL10interleukin 100.203
PTPN1protein tyrosine phosphatase, non-receptor type 10.199
CCL7chemokine (C-C motif) ligand 70.196
TNFRSF1Atumor necrosis factor receptor superfamily, member 1A0.194
IL23Ainterleukin 23, alpha subunit p190.187
TNFRSF6Btumor necrosis factor receptor superfamily, member 6b, decoy0.185
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.179
MESTmesoderm specific transcript homolog (mouse)0.176
CXCL3chemokine (C-X-C motif) ligand 30.174
CXCL13chemokine (C-X-C motif) ligand 130.168
ZNF680zinc finger protein 6800.167
CCL2chemokine (C-C motif) ligand 20.163
CCL13chemokine (C-C motif) ligand 130.154
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.151
CXCR6chemokine (C-X-C motif) receptor 60.149
NOTCH1notch 10.146
FADDFas (TNFRSF6)-associated via death domain0.145
TRAF3TNF receptor-associated factor 30.144
CCL11chemokine (C-C motif) ligand 110.140
CASP7caspase 7, apoptosis-related cysteine peptidase0.139
CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.139
IL16interleukin 16 (lymphocyte chemoattractant factor)0.136
CXCR3chemokine (C-X-C motif) receptor 30.136
GSK3Bglycogen synthase kinase 3 beta0.136
HTThuntingtin0.129
ZNF117zinc finger protein 1170.127
DIP2ADIP2 disco-interacting protein 2 homolog A (Drosophila)0.126
SIRPB1signal-regulatory protein beta 10.123
LRDDleucine-rich repeats and death domain containing0.122
GHRgrowth hormone receptor0.119
C1QCcomplement component 1, q subcomponent, C chain0.115
CASP10caspase 10, apoptosis-related cysteine peptidase0.115
APAF1apoptotic peptidase activating factor 10.109
ATF2activating transcription factor 20.109
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ptenphosphatase and tensin homolog1.000
Ikzf1IKAROS family zinc finger 10.998
Pax8paired box gene 80.996
Csf1colony stimulating factor 1 (macrophage)0.996
Trp53transformation related protein 530.993
Gata1GATA binding protein 10.981
Kitkit oncogene0.967
Robo1roundabout homolog 1 (Drosophila)0.964
Ctnnb1catenin (cadherin associated protein), beta 10.964
Kiss1KiSS-1 metastasis-suppressor0.940
Esr1estrogen receptor 1 (alpha)0.933
Ptpn11protein tyrosine phosphatase, non-receptor type 110.932
Tgfb1transforming growth factor, beta 10.927
Lyz2lysozyme 20.926
Stat3signal transducer and activator of transcription 30.914
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.895
Thrathyroid hormone receptor alpha0.837
Arandrogen receptor0.813
Rxraretinoid X receptor alpha0.789
Mdm2transformed mouse 3T3 cell double minute 20.787
Notch1Notch gene homolog 1 (Drosophila)0.783
Foxc2forkhead box C20.757
Gata4GATA binding protein 40.746
JunJun oncogene0.744
Id1inhibitor of DNA binding 10.738
Id3inhibitor of DNA binding 30.727
Sfrp2secreted frizzled-related protein 20.687
Lhx3LIM homeobox protein 30.680
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.676
Csf2colony stimulating factor 2 (granulocyte-macrophage)0.673
Inpp5dinositol polyphosphate-5-phosphatase D0.664
Tnftumor necrosis factor0.658
Leprleptin receptor0.656
Ighimmunoglobulin heavy chain complex0.644
Rararetinoic acid receptor, alpha0.640
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.629
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.609
CblCasitas B-lineage lymphoma0.607
Rargretinoic acid receptor, gamma0.602
Nr3c1nuclear receptor subfamily 3, group C, member 10.601
Stat5bsignal transducer and activator of transcription 5B0.589
Neurod1neurogenic differentiation 10.588
Plcg2phospholipase C, gamma 20.585
Ascl1achaete-scute complex homolog 1 (Drosophila)0.578
Smad3MAD homolog 3 (Drosophila)0.572
Il2rginterleukin 2 receptor, gamma chain0.564
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.563
Duox2dual oxidase 20.551
Vdrvitamin D receptor0.539
Ppargperoxisome proliferator activated receptor gamma0.537
Pitx2paired-like homeodomain transcription factor 20.524
FosFBJ osteosarcoma oncogene0.519
Otx2orthodenticle homolog 2 (Drosophila)0.518
Stat5asignal transducer and activator of transcription 5A0.518
Pax6paired box gene 60.513
Ghrgrowth hormone receptor0.512
Ltblymphotoxin B0.510
Rbl2retinoblastoma-like 20.504
Notch2Notch gene homolog 2 (Drosophila)0.496
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.493
Rarbretinoic acid receptor, beta0.481
Fcgr2bFc receptor, IgG, low affinity IIb0.475
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.474
WasWiskott-Aldrich syndrome homolog (human)0.470
Prlrprolactin receptor0.463
Inhbainhibin beta-A0.462
Slit3slit homolog 3 (Drosophila)0.459
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.454
Hes1hairy and enhancer of split 1 (Drosophila)0.444
Clockcircadian locomotor output cycles kaput0.443
Fgfr2fibroblast growth factor receptor 20.438
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.430
Irs2insulin receptor substrate 20.428
Gli2GLI-Kruppel family member GLI20.426
FasFas (TNF receptor superfamily member 6)0.413
Adam17a disintegrin and metallopeptidase domain 170.412
Nos3nitric oxide synthase 3, endothelial cell0.393
Neurog2neurogenin 20.380
Snai1snail homolog 1 (Drosophila)0.369
Sox11SRY-box containing gene 110.364
Runx1runt related transcription factor 10.362
MecomMDS1 and EVI1 complex locus0.356
Gnrh1gonadotropin releasing hormone 10.349
Slit2slit homolog 2 (Drosophila)0.348
Cav1caveolin 1, caveolae protein0.348
Il2interleukin 20.348
Il6stinterleukin 6 signal transducer0.347
Nr5a1nuclear receptor subfamily 5, group A, member 10.345
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.341
Csf1rcolony stimulating factor 1 receptor0.341
Fgd1FYVE, RhoGEF and PH domain containing 10.338
Rb1retinoblastoma 10.335
Lhcgrluteinizing hormone/choriogonadotropin receptor0.334
Klklotho0.323
Bmpr1abone morphogenetic protein receptor, type 1A0.313
Stat6signal transducer and activator of transcription 60.312
Dll1delta-like 1 (Drosophila)0.308
Ptpn6protein tyrosine phosphatase, non-receptor type 60.307
Eporerythropoietin receptor0.303
Bglapbone gamma carboxyglutamate protein0.302
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Atf3activating transcription factor 30.208
Ctsscathepsin S0.081
Dusp1dual specificity phosphatase 10.079
Il2rbinterleukin 2 receptor, beta0.073
Klf4Kruppel-like factor 4 (gut)0.071
Junbjun B proto-oncogene0.054
Egr2early growth response 20.049
Plauplasminogen activator, urokinase0.045
Fcn1ficolin (collagen/fibrinogen domain containing) 10.041
CblCas-Br-M (murine) ecotropic retroviral transforming sequence0.039
Il1binterleukin 1 beta0.038
Cfpcomplement factor properdin0.035
Cd86CD86 molecule0.028
Ccl4chemokine (C-C motif) ligand 40.027
Btg2BTG family, member 20.023
JunJun oncogene0.023
Ccl3chemokine (C-C motif) ligand 30.023
Zfp36zinc finger protein 360.020
Egr1early growth response 10.018
Reg3bregenerating islet-derived 3 beta0.018
Ier2immediate early response 20.017
Errfi1ERBB receptor feedback inhibitor 10.017
Galnt5UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)0.015
Chrnecholinergic receptor, nicotinic, epsilon0.015
Myl6lmyosin, light polypeptide 6, alkali, smooth muscle and non-muscle-like0.015
Il8rbinterleukin 8 receptor, beta0.014
Nckap1lNCK associated protein 1 like0.014
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.013
Itpr2inositol 1,4,5-triphosphate receptor, type 20.013
RGD1359529similar to chromosome 1 open reading frame 630.013
Nr4a3nuclear receptor subfamily 4, group A, member 30.013
Nhp2NHP2 ribonucleoprotein homolog (yeast)0.012
Klf6Kruppel-like factor 60.012
Prrx1paired related homeobox 10.012
Rassf5Ras association (RalGDS/AF-6) domain family member 50.012
Laptm5lysosomal protein transmembrane 50.012
Hspa1aheat shock 70kD protein 1A0.012
Rgs1regulator of G-protein signaling 10.011
Arhgap4Rho GTPase activating protein 40.011
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.011
Il1ainterleukin 1 alpha0.011
Notch2Notch homolog 2 (Drosophila)0.011
Cd247Cd247 molecule0.011
Cd83CD83 molecule0.011
Acacbacetyl-Coenzyme A carboxylase beta0.011
Tcf12transcription factor 120.011
Ccl2chemokine (C-C motif) ligand 20.010
Eif5aeukaryotic translation initiation factor 5A0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism