The network for 'asymmetric neuroblast division' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

asymmetric neuroblast division

The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.

NameDescriptionProbabilityFunc Analog Organism
numbCG3779 gene product from transcript CG3779-RB1.000
Ggamma1G protein gamma 10.999
G-ialpha65AG protein alphai subunit 65A0.999
G-oalpha47AG protein oalpha 47A0.999
Rab5Rab-protein 50.984
Sas-4CG10061 gene product from transcript CG10061-RA0.929
CtBPC-terminal Binding Protein0.906
SAKSak kinase0.876
sas-6spindle assembly abnormal 60.868
emcextra macrochaetae0.830
drkdownstream of receptor kinase0.803
CG5690CG5690 gene product from transcript CG5690-RA0.640
Cep135CG17081 gene product from transcript CG17081-RB0.626
Rac1CG2248 gene product from transcript CG2248-RA0.587
CkIalphaCasein kinase Ialpha0.575
Poc1Proteome of centrioles 10.573
CG15436CG15436 gene product from transcript CG15436-RA0.557
CG6954CG6954 gene product from transcript CG6954-RB0.545
CG10267CG10267 gene product from transcript CG10267-RB0.541
bambag of marbles0.509
Grip71CG10346 gene product from transcript CG10346-RA0.479
locolocomotion defects0.444
Cp110CG14617 gene product from transcript CG14617-RB0.441
Gbeta13FG protein beta-subunit 13F0.433
Adf1Adh transcription factor 10.420
ana3anastral spindle 30.411
sleslender lobes0.388
mtsmicrotubule star0.351
stumpsCG31317 gene product from transcript CG31317-RC0.327
par-6CG5884 gene product from transcript CG5884-RA0.310
lkb1CG9374 gene product from transcript CG9374-RJ0.296
EphrinCG1862 gene product from transcript CG1862-RA0.292
rodrough deal0.287
cdicenter divider0.282
PknProtein kinase related to protein kinase N0.253
ShcSHC-adaptor protein0.249
ana2anastral spindle 20.248
Galpha49BG protein alpha49B0.236
Cdc42CG12530 gene product from transcript CG12530-RA0.230
prodproliferation disrupter0.208
BicDBicaudal D0.208
InvadolysinCG3953 gene product from transcript CG3953-RA0.183
norpAno receptor potential A0.163
PPP4R2rProtein phosphatase 4 regulatory subunit 2-related protein0.160
Tre1trapped in endoderm-10.156
14-3-3zetaCG17870 gene product from transcript CG17870-RB0.150
Orc6Origin recognition complex subunit 60.148
par-1CG8201 gene product from transcript CG8201-RA0.141
Pp2A-29BProtein phosphatase 2A at 29B0.131
CG14667CG14667 gene product from transcript CG14667-RA0.130
chbchromosome bows0.123
MaxCG9648 gene product from transcript CG9648-RA0.122
MybMyb oncogene-like0.121
Spc25CG7242 gene product from transcript CG7242-RA0.121
Bj1Bj1 protein0.119
hipkhomeodomain interacting protein kinase0.117
sinaseven in absentia0.112
CG5199CG5199 gene product from transcript CG5199-RA0.111
dlg1discs large 10.110
Cdk4Cyclin-dependent kinase 40.106
zpgzero population growth0.105
mubmushroom-body expressed0.103
CortactinCG3637 gene product from transcript CG3637-RA0.102
alpha-AdaptinCG4260 gene product from transcript CG4260-RA0.093
aPKCatypical protein kinase C0.093
poloCG12306 gene product from transcript CG12306-RA0.092
l(2)gllethal (2) giant larvae0.090
l(2)05714lethal (2) 057140.089
CG6843CG6843 gene product from transcript CG6843-RA0.086
inaDinactivation no afterpotential D0.084
CycDCyclin D0.083
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
goa-1Protein GOA-10.658
dcap-2Protein DCAP-20.582
par-1Protein PAR-10.173
inx-3Protein INX-30.161
cam-1Protein CAM-10.134
patr-1Protein PATR-10.131
lag-1Protein LAG-10.117
tax-6Protein TAX-60.111
K10C3.4Protein K10C3.40.107
sem-5Protein SEM-50.105
T26C12.1Protein T26C12.10.103
sel-10Protein SEL-100.097
skpt-1Protein SKPT-10.086
cnt-2Protein CNT-20.069
sel-12Protein SEL-120.048
bath-43Protein BATH-430.046
mes-4Protein MES-40.043
F39B2.1Protein F39B2.10.041
dhhc-1Protein DHHC-10.039
unc-94Protein UNC-940.037
pig-1Protein PIG-10.035
cit-1.1Protein CIT-1.10.031
anc-1Protein ANC-10.030
ZK507.6Protein ZK507.60.028
egl-30Protein EGL-300.027
sun-1Protein SUN-10.027
CELE_Y39G8B.2Protein Y39G8B.20.026
C05D11.7Protein C05D11.70.026
dcp-66Protein DCP-660.026
let-92Protein LET-920.024
F10B5.2Protein F10B5.20.024
sur-2Protein SUR-20.024
tbc-3Protein TBC-30.024
pptr-2Protein PPTR-20.023
pkg-1Protein PKG-10.023
T12B3.4Protein T12B3.40.023
tat-1Protein TAT-10.021
Y119C1A.1Protein Y119C1A.10.021
nhr-6Protein NHR-60.020
ztf-8Protein ZTF-80.019
gei-4Protein GEI-40.019
T28D9.4Protein T28D9.40.018
egl-18Protein EGL-180.017
ash-2Protein ASH-20.017
sex-1Protein SEX-10.017
F16A11.1Protein F16A11.10.017
pct-1Protein PCT-10.016
daf-5Protein DAF-50.016
fzr-1Protein FZR-10.016
rad-51Protein RAD-510.016
F52D10.2Protein F52D10.20.015
gpb-1Protein GPB-10.015
H14A12.3Protein H14A12.30.014
tpa-1Protein TPA-10.014
Y59E9AL.4Protein Y59E9AL.40.014
cap-1Protein CAP-10.014
unc-32Protein UNC-320.014
hlh-30Protein HLH-300.014
gla-3Protein GLA-30.014
unc-9Protein UNC-90.013
paa-1Protein PAA-10.013
hbl-1Protein HBL-10.013
CELE_C25A1.5Protein C25A1.50.012
T15B7.1Protein T15B7.10.012
sup-17Protein SUP-170.012
F22D3.2Protein F22D3.20.012
let-502Protein LET-5020.012
rab-11.1Protein RAB-11.10.011
ima-3Protein IMA-30.011
dpy-27Protein DPY-270.011
aph-2Protein APH-20.011
gadr-6Protein GADR-60.011
gsp-1Protein GSP-10.011
dnj-5Protein DNJ-50.011
F12F6.1Protein F12F6.10.011
B0024.11Protein B0024.110.011
CELE_C10C6.6Protein C10C6.60.011
nhl-3Protein NHL-30.011
pro-2Protein PRO-20.011
par-4Protein PAR-40.011
C41D11.4Protein C41D11.40.010
ddx-19Protein DDX-190.010
CELE_F02E9.10Protein F02E9.100.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PRKCZprotein kinase C, zeta1.000
CCT8chaperonin containing TCP1, subunit 8 (theta)1.000
STK11serine/threonine kinase 111.000
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)1.000
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)1.000
CCT4chaperonin containing TCP1, subunit 4 (delta)0.999
CDK2cyclin-dependent kinase 20.998
TCP1t-complex 10.996
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.986
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.983
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.982
MAPTmicrotubule-associated protein tau0.978
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.978
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.974
PPP4Cprotein phosphatase 4, catalytic subunit0.972
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.966
CENPJcentromere protein J0.964
STRADASTE20-related kinase adaptor alpha0.946
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.938
ZBED1zinc finger, BED-type containing 10.903
PRKCIprotein kinase C, iota0.883
JUBjub, ajuba homolog (Xenopus laevis)0.837
PPP2R2Cprotein phosphatase 2, regulatory subunit B, gamma0.824
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.772
STRN3striatin, calmodulin binding protein 30.768
MAP3K3mitogen-activated protein kinase kinase kinase 30.712
CCNB1cyclin B10.702
CCT5chaperonin containing TCP1, subunit 5 (epsilon)0.681
PKP2plakophilin 20.672
STRADBSTE20-related kinase adaptor beta0.649
TNIP2TNFAIP3 interacting protein 20.618
LLGL1lethal giant larvae homolog 1 (Drosophila)0.606
MARK2MAP/microtubule affinity-regulating kinase 20.589
NCF2neutrophil cytosolic factor 20.578
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.554
CCDC158coiled-coil domain containing 1580.536
NGFnerve growth factor (beta polypeptide)0.516
PPP2R1Bprotein phosphatase 2, regulatory subunit A, beta0.515
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.451
MARK4MAP/microtubule affinity-regulating kinase 40.432
CAB39calcium binding protein 390.385
AP2A1adaptor-related protein complex 2, alpha 1 subunit0.384
SKA3spindle and kinetochore associated complex subunit 30.358
SKP2S-phase kinase-associated protein 2 (p45)0.327
RBFOX1RNA binding protein, fox-1 homolog (C. elegans) 10.319
PLCG1phospholipase C, gamma 10.316
CCNB2cyclin B20.302
CCNE1cyclin E10.283
SNCAsynuclein, alpha (non A4 component of amyloid precursor)0.266
RFWD2ring finger and WD repeat domain 20.259
MOBKL3MOB1, Mps One Binder kinase activator-like 3 (yeast)0.254
NUMA1nuclear mitotic apparatus protein 10.243
MOBKL1BMOB1, Mps One Binder kinase activator-like 1B (yeast)0.242
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.239
F11RF11 receptor0.236
CCT6Achaperonin containing TCP1, subunit 6A (zeta 1)0.235
ARHGEF2Rho/Rac guanine nucleotide exchange factor (GEF) 20.224
OXSR1oxidative-stress responsive 10.218
STK39serine threonine kinase 390.210
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.210
PKP3plakophilin 30.208
BCAR1breast cancer anti-estrogen resistance 10.196
PAK3p21 protein (Cdc42/Rac)-activated kinase 30.176
ARL6IP1ADP-ribosylation factor-like 6 interacting protein 10.173
GNG2guanine nucleotide binding protein (G protein), gamma 20.169
CAPZBcapping protein (actin filament) muscle Z-line, beta0.168
PLCB3phospholipase C, beta 3 (phosphatidylinositol-specific)0.164
SASS6spindle assembly 6 homolog (C. elegans)0.163
VHLvon Hippel-Lindau tumor suppressor0.161
MAP2K5mitogen-activated protein kinase kinase 50.149
CDH5cadherin 5, type 2 (vascular endothelium)0.148
TRAF5TNF receptor-associated factor 50.148
NTF4neurotrophin 40.147
CKS2CDC28 protein kinase regulatory subunit 20.136
SHC3SHC (Src homology 2 domain containing) transforming protein 30.136
HMGB2high mobility group box 20.136
GNB4guanine nucleotide binding protein (G protein), beta polypeptide 40.122
PAK4p21 protein (Cdc42/Rac)-activated kinase 40.107
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.107
ZNF71zinc finger protein 710.107
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.099
FYNFYN oncogene related to SRC, FGR, YES0.098
AKT1v-akt murine thymoma viral oncogene homolog 10.097
C22orf39chromosome 22 open reading frame 390.095
IQGAP2IQ motif containing GTPase activating protein 20.094
ZC3HAV1zinc finger CCCH-type, antiviral 10.094
PAK7p21 protein (Cdc42/Rac)-activated kinase 70.093
CKS1BCDC28 protein kinase regulatory subunit 1B0.087
KIF23kinesin family member 230.087
MOBKL1AMOB1, Mps One Binder kinase activator-like 1A (yeast)0.087
MARK1MAP/microtubule affinity-regulating kinase 10.085
SQSTM1sequestosome 10.084
NUMBnumb homolog (Drosophila)0.084
PPME1protein phosphatase methylesterase 10.078
TP53tumor protein p530.077
GNAI1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 10.075
ARPC5actin related protein 2/3 complex, subunit 5, 16kDa0.074
STILSCL/TAL1 interrupting locus0.074
GGHgamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)0.072
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ntf3neurotrophin 30.997
Shhsonic hedgehog0.996
Gli3GLI-Kruppel family member GLI30.996
Bdnfbrain derived neurotrophic factor0.991
Gli2GLI-Kruppel family member GLI20.990
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.990
Rac1RAS-related C3 botulinum substrate 10.989
Pax2paired box gene 20.975
Ctnnb1catenin (cadherin associated protein), beta 10.971
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.930
Tbx10T-box 100.927
Hoxa1homeobox A10.917
Fgfr2fibroblast growth factor receptor 20.909
Efnb2ephrin B20.883
Twist2twist homolog 2 (Drosophila)0.881
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.857
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.853
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.843
Fgfr3fibroblast growth factor receptor 30.830
Zfpm2zinc finger protein, multitype 20.828
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.778
Esr1estrogen receptor 1 (alpha)0.774
Sox2SRY-box containing gene 20.773
Isl1ISL1 transcription factor, LIM/homeodomain0.752
Fgf9fibroblast growth factor 90.747
Kitlkit ligand0.719
ArhgdiaRho GDP dissociation inhibitor (GDI) alpha0.711
Pou4f3POU domain, class 4, transcription factor 30.705
Vangl2vang-like 2 (van gogh, Drosophila)0.688
Bmpr1abone morphogenetic protein receptor, type 1A0.684
Foxc1forkhead box C10.666
Jag1jagged 10.660
Eya1eyes absent 1 homolog (Drosophila)0.657
Nr2f1nuclear receptor subfamily 2, group F, member 10.656
Sox9SRY-box containing gene 90.653
Zeb1zinc finger E-box binding homeobox 10.647
Fgf8fibroblast growth factor 80.635
Wnt5awingless-related MMTV integration site 5A0.616
Prrx1paired related homeobox 10.615
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.609
Hoxd13homeobox D130.606
Ror2receptor tyrosine kinase-like orphan receptor 20.590
Hand2heart and neural crest derivatives expressed transcript 20.586
Cdk1cyclin-dependent kinase 10.582
Ccnb2cyclin B20.577
Ccnb1cyclin B10.560
Emx1empty spiracles homolog 1 (Drosophila)0.556
Gabrb3gamma-aminobutyric acid (GABA) A receptor, subunit beta 30.554
Msx2homeobox, msh-like 20.552
Cdk2cyclin-dependent kinase 20.550
Otx2orthodenticle homolog 2 (Drosophila)0.541
Cfl1cofilin 1, non-muscle0.533
Hoxd11homeobox D110.492
Hey2hairy/enhancer-of-split related with YRPW motif 20.492
Tcf21transcription factor 210.491
Tbx3T-box 30.485
Nr2f2nuclear receptor subfamily 2, group F, member 20.466
Syt9synaptotagmin IX0.448
Foxg1forkhead box G10.445
Trp63transformation related protein 630.438
Prkczprotein kinase C, zeta0.437
Pthlhparathyroid hormone-like peptide0.436
Arhgap1Rho GTPase activating protein 10.429
Fgf14fibroblast growth factor 140.428
Ptk7PTK7 protein tyrosine kinase 70.418
Dnajb5DnaJ (Hsp40) homolog, subfamily B, member 50.409
Smad3MAD homolog 3 (Drosophila)0.407
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.402
Wdr1WD repeat domain 10.384
Akt1thymoma viral proto-oncogene 10.381
Bmp5bone morphogenetic protein 50.378
Retret proto-oncogene0.363
Hdac7histone deacetylase 70.361
Fgfr1fibroblast growth factor receptor 10.361
Tbx15T-box 150.351
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.340
Capzbcapping protein (actin filament) muscle Z-line, beta0.334
Meox2mesenchyme homeobox 20.332
Ephb2Eph receptor B20.328
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.325
Shc3src homology 2 domain-containing transforming protein C30.319
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.316
Sult4a1sulfotransferase family 4A, member 10.313
Tgfb2transforming growth factor, beta 20.312
Gata4GATA binding protein 40.311
Col2a1collagen, type II, alpha 10.305
Gli1GLI-Kruppel family member GLI10.301
Plcg1phospholipase C, gamma 10.297
Ptenphosphatase and tensin homolog0.295
Fbn2fibrillin 20.292
Chd7chromodomain helicase DNA binding protein 70.292
Pax3paired box gene 30.290
Ahraryl-hydrocarbon receptor0.284
Gbx2gastrulation brain homeobox 20.283
Rasgrp1RAS guanyl releasing protein 10.274
Cdk5r1cyclin-dependent kinase 5, regulatory subunit 1 (p35)0.272
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism