The network for 'chondroitin sulfate proteoglycan metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

chondroitin sulfate proteoglycan metabolic process

The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.

NameDescriptionProbabilityFunc Analog Organism
Ext2CG8433 gene product from transcript CG8433-RA0.988
botvbrother of tout-velu0.913
O-fut1O-fucosyltransferase 10.119
Bre1CG10542 gene product from transcript CG10542-RA0.048
Mo25CG4083 gene product from transcript CG4083-RA0.032
EloAElongin A0.031
raspCG11495 gene product from transcript CG11495-RA0.029
CG5390CG5390 gene product from transcript CG5390-RA0.025
frcfringe connection0.022
CG7536CG7536 gene product from transcript CG7536-RB0.022
CG9870CG9870 gene product from transcript CG9870-RA0.018
CG31140CG31140 gene product from transcript CG31140-RF0.017
CG10277CG10277 gene product from transcript CG10277-RB0.017
CG9139CG9139 gene product from transcript CG9139-RA0.014
Cyp18a1Cytochrome P450-18a10.014
CG31915CG31915 gene product from transcript CG31915-RA0.013
Jon65AivJonah 65Aiv0.013
CG32372CG32372 gene product from transcript CG32372-RA0.013
rtettetracycline resistance0.012
GrafCG8948 gene product from transcript CG8948-RB0.012
CG16857CG16857 gene product from transcript CG16857-RA0.012
CG13928CG13928 gene product from transcript CG13928-RA0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
F25H2.7Protein F25H2.70.088
CELE_C25A1.5Protein C25A1.50.020
acl-11Protein ACL-110.014
tpk-1Protein TPK-10.014
rde-1Protein RDE-10.013
W01D2.5Protein W01D2.50.011
C13B4.1Protein C13B4.10.011
Y53C12A.3Protein Y53C12A.30.011
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
extl3exostoses (multiple)-like 30.950
sec24dSEC24 family, member D (S. cerevisiae)0.816
uxs1UDP-glucuronic acid decarboxylase 10.316
plcb3phospholipase C, beta 3 (phosphatidylinositol-specific)0.281
slc35b2solute carrier family 35, member B20.173
fibinfin bud initiation factor0.113
arl4caADP-ribosylation factor-like 4Ca0.096
col12a1collagen, type XII, alpha 10.089
disp1dispatched homolog 1 (Drosophila)0.064
gle1GLE1 RNA export mediator homolog (yeast)0.061
sec13SEC13 homolog (S. cerevisiae)0.055
col27a1acollagen, type XXVII, alpha 1a0.050
lhfplipoma HMGIC fusion partner0.042
marcksl1MARCKS-like 10.040
rcn1reticulocalbin 1, EF-hand calcium binding domain0.037
scxascleraxis homolog A (mouse)0.037
b3gat3beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) and beta3-glucuronyltransferase0.036
postnperiostin, osteoblast specific factor0.034
s1pr2sphingosine-1-phosphate receptor 20.032
sufusuppressor of fused homolog (Drosophila)0.031
st3gal2lST3 beta-galactoside alpha-2,3-sialyltransferase 2, like0.031
olfml3bolfactomedin-like 3b0.030
vaspvasodilator-stimulated phosphoprotein0.028
csnk1a1casein kinase 1, alpha 10.028
ugdhUDP-glucose dehydrogenase0.027
col11a1acollagen, type XI, alpha 1a0.025
inppl1ainositol polyphosphate phosphatase-like 1a0.024
xylt1xylosyltransferase 10.021
col5a2lcollagen, type V, alpha 2-like0.020
c8acomplement component 8, alpha polypeptide0.019
ecm2extracellular matrix protein 2, female organ and adipocyte specific0.019
mxra8bmatrix-remodelling associated 8b0.018
inhainhibin, alpha0.018
ltkleukocyte tyrosine kinase0.016
plod2procollagen-lysine, 2-oxoglutarate 5-dioxygenase 20.016
lamc1laminin, gamma 10.015
pid1phosphotyrosine interaction domain containing 10.014
pmp22aperipheral myelin protein 22a0.014
col1a1bcollagen, type I, alpha 1b0.014
hgdhomogentisate 1,2-dioxygenase0.014
efemp2EGF-containing fibulin-like extracellular matrix protein 20.013
bmpr1aabone morphogenetic protein receptor, type 1aa0.013
thbs1thrombospondin 10.013
acin1bapoptotic chromatin condensation inducer 1b0.013
serpinf1serine (or cysteine) peptidase inhibitor, clade F, member 10.012
fam20bfamily with sequence similarity 20, member B (H. sapiens)0.012
angptl7angiopoietin-like 70.012
gdf9growth differentiation factor 90.012
pdia5protein disulfide isomerase family A, member 50.011
emilin1belastin microfibril interfacer 1b0.011
col5a1procollagen, type V, alpha 10.011
inhbabinhibin, beta Ab0.011
piguphosphatidylinositol glycan anchor biosynthesis, class U0.011
ext2exostoses (multiple) 20.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
COL6A1collagen, type VI, alpha 10.354
COL1A1collagen, type I, alpha 10.132
BNIP2BCL2/adenovirus E1B 19kDa interacting protein 20.111
PCOLCEprocollagen C-endopeptidase enhancer0.103
COL14A1collagen, type XIV, alpha 10.092
COL1A2collagen, type I, alpha 20.066
ARFGAP3ADP-ribosylation factor GTPase activating protein 30.065
LAMA2laminin, alpha 20.053
MXRA5matrix-remodelling associated 50.050
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.049
MFAP2microfibrillar-associated protein 20.043
ISLRimmunoglobulin superfamily containing leucine-rich repeat0.042
OLFML3olfactomedin-like 30.040
MRC2mannose receptor, C type 20.038
COL6A2collagen, type VI, alpha 20.037
KLF10Kruppel-like factor 100.037
CXCL12chemokine (C-X-C motif) ligand 120.032
LTBP2latent transforming growth factor beta binding protein 20.032
CHSY1chondroitin sulfate synthase 10.031
GLT8D2glycosyltransferase 8 domain containing 20.030
FBN1fibrillin 10.030
ECM2extracellular matrix protein 2, female organ and adipocyte specific0.025
MAN1B1mannosidase, alpha, class 1B, member 10.025
LOXlysyl oxidase0.025
MGPmatrix Gla protein0.023
FBLN2fibulin 20.021
C1Scomplement component 1, s subcomponent0.021
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.021
ZNF267zinc finger protein 2670.020
SEC24ASEC24 family, member A (S. cerevisiae)0.020
PTGDSprostaglandin D2 synthase 21kDa (brain)0.020
FNDC3Bfibronectin type III domain containing 3B0.018
CSGALNACT2chondroitin sulfate N-acetylgalactosaminyltransferase 20.018
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)0.017
ADH1Balcohol dehydrogenase 1B (class I), beta polypeptide0.017
MFAP5microfibrillar associated protein 50.017
MFAP4microfibrillar-associated protein 40.017
FAPfibroblast activation protein, alpha0.017
GPC1glypican 10.016
C1Rcomplement component 1, r subcomponent0.016
COL6A3collagen, type VI, alpha 30.016
OLFML2Bolfactomedin-like 2B0.015
B4GALT7xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)0.015
ZEB2zinc finger E-box binding homeobox 20.015
PRRX1paired related homeobox 10.014
RCN3reticulocalbin 3, EF-hand calcium binding domain0.014
CTSKcathepsin K0.013
PLXDC1plexin domain containing 10.013
IGFBP4insulin-like growth factor binding protein 40.013
COL4A2collagen, type IV, alpha 20.013
SULF1sulfatase 10.013
YIPF2Yip1 domain family, member 20.012
CILPcartilage intermediate layer protein, nucleotide pyrophosphohydrolase0.012
PTGISprostaglandin I2 (prostacyclin) synthase0.012
GJA4gap junction protein, alpha 4, 37kDa0.011
AEBP1AE binding protein 10.011
FAM3Afamily with sequence similarity 3, member A0.011
ITGBL1integrin, beta-like 1 (with EGF-like repeat domains)0.011
THBS2thrombospondin 20.011
EDNRAendothelin receptor type A0.011
FBLN5fibulin 50.011
C7complement component 70.011
LOXL1lysyl oxidase-like 10.011
COMPcartilage oligomeric matrix protein0.010
ACSL4acyl-CoA synthetase long-chain family member 40.010
IGFBP3insulin-like growth factor binding protein 30.010
FBLN1fibulin 10.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
H2-Aahistocompatibility 2, class II antigen A, alpha0.933
Ghrgrowth hormone receptor0.150
H2-DMahistocompatibility 2, class II, locus DMa0.141
Ins1insulin I0.134
Serping1serine (or cysteine) peptidase inhibitor, clade G, member 10.129
Dag1dystroglycan 10.128
H2-Eb1histocompatibility 2, class II antigen E beta0.120
Islrimmunoglobulin superfamily containing leucine-rich repeat0.108
Col1a1collagen, type I, alpha 10.097
Ctrb1chymotrypsinogen B10.090
Pkd1polycystic kidney disease 1 homolog0.086
Cdkn1ccyclin-dependent kinase inhibitor 1C (P57)0.070
H2-Ab1histocompatibility 2, class II antigen A, beta 10.062
Postnperiostin, osteoblast specific factor0.056
Colec12collectin sub-family member 120.052
Krt4keratin 40.050
Angpt4angiopoietin 40.049
Lrrc58leucine rich repeat containing 580.047
Col1a2collagen, type I, alpha 20.046
Cfhcomplement component factor h0.045
Igf1rinsulin-like growth factor I receptor0.045
Igf2rinsulin-like growth factor 2 receptor0.044
C1scomplement component 1, s subcomponent0.044
Ins2insulin II0.043
Mrc1mannose receptor, C type 10.038
Abi3bpABI gene family, member 3 (NESH) binding protein0.035
Amhr2anti-Mullerian hormone type 2 receptor0.033
Col3a1collagen, type III, alpha 10.032
Krtap5-1keratin associated protein 5-10.030
Naalad2N-acetylated alpha-linked acidic dipeptidase 20.030
Ltbp4latent transforming growth factor beta binding protein 40.029
Kiss1KiSS-1 metastasis-suppressor0.026
2210010C04RikRIKEN cDNA 2210010C04 gene0.026
Prelpproline arginine-rich end leucine-rich repeat0.025
Col2a1collagen, type II, alpha 10.025
Serpinf1serine (or cysteine) peptidase inhibitor, clade F, member 10.025
Abca2ATP-binding cassette, sub-family A (ABC1), member 20.024
Htr5b5-hydroxytryptamine (serotonin) receptor 5B0.024
Npc1Niemann Pick type C10.024
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.023
Dlx4distal-less homeobox 40.023
Reg4regenerating islet-derived family, member 40.023
Insrinsulin receptor0.022
Kdelc2KDEL (Lys-Asp-Glu-Leu) containing 20.020
Tubb4tubulin, beta 40.019
Treml1triggering receptor expressed on myeloid cells-like 10.019
Tnxbtenascin XB0.019
Sod3superoxide dismutase 3, extracellular0.018
Skiski sarcoma viral oncogene homolog (avian)0.018
Gpa33glycoprotein A33 (transmembrane)0.018
Pbp2phosphatidylethanolamine binding protein 20.018
Akt1thymoma viral proto-oncogene 10.018
Cacna1fcalcium channel, voltage-dependent, alpha 1F subunit0.018
Col14a1collagen, type XIV, alpha 10.018
Aebp1AE binding protein 10.018
Cacng4calcium channel, voltage-dependent, gamma subunit 40.018
2010003K11RikRIKEN cDNA 2010003K11 gene0.017
Tff1trefoil factor 10.017
Igfbp6insulin-like growth factor binding protein 60.017
Mfap5microfibrillar associated protein 50.017
Matn2matrilin 20.017
Dab2ipdisabled homolog 2 (Drosophila) interacting protein0.017
Celcarboxyl ester lipase0.017
Cfc1cripto, FRL-1, cryptic family 10.017
Galnt2UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 20.017
Foxo3forkhead box O30.016
Muc5acmucin 5, subtypes A and C, tracheobronchial/gastric0.016
Msh4mutS homolog 4 (E. coli)0.016
Efemp1epidermal growth factor-containing fibulin-like extracellular matrix protein 10.016
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.016
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.016
Slc14a2solute carrier family 14 (urea transporter), member 20.016
Vdrvitamin D receptor0.016
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.016
Slc45a2solute carrier family 45, member 20.016
Col6a1collagen, type VI, alpha 10.016
1700080E11RikRIKEN cDNA 1700080E11 gene0.016
Cryaacrystallin, alpha A0.015
Ptprsprotein tyrosine phosphatase, receptor type, S0.015
Thbs2thrombospondin 20.015
Prkar1bprotein kinase, cAMP dependent regulatory, type I beta0.015
Zeb2zinc finger E-box binding homeobox 20.015
Meis3Meis homeobox 30.015
Ptpruprotein tyrosine phosphatase, receptor type, U0.015
Clec14aC-type lectin domain family 14, member a0.015
Ncor2nuclear receptor co-repressor 20.015
Igfbp5insulin-like growth factor binding protein 50.014
Pkd2polycystic kidney disease 20.014
Foxn4forkhead box N40.014
Zg16zymogen granule protein 160.014
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism